Effect of non-surgical periodontal treatment on visfatin and chemerin concentration in the gingival crevicular fluid
AbstractVisfatin, as a novel adipokine, is considered to play a role in periodontal inflammation. Chemerin is another newly identified adipokine that is possible to have a role in periodontitis firstly reported in our previous study. The aim of the current study is to evaluate the gingival crevicular fluid (GCF) levels of visfatin and chemerin in periodontitis and and compare these adipokine levels with before and after non-surgical periodontal treatment. Twenty-nine patients with Stage III Grade B periodontitis and eighteen healthy subjects included in this cross-sectional cohort study. Clinical periodontal parameters and...
Source: Odontology - January 1, 2024 Category: Dentistry Source Type: research

A diet rich in omega-3 fatty acid improves periodontitis and tissue destruction by MMP2- and MMP9-linked inflammation in a murine model
AbstractPeriodontitis is an oral-cavity inflammatory disease and is the principal cause associated with tooth loss. Matrix metalloproteinases 2 and 9 (MMP-2 and MMP-9) are important proteases involved in periodontal tissue destruction. The omega-3 polyunsaturated fatty acids ( ω-3 PUFA) have been demonstrated to possess immunoregulatory properties in periodontitis. The aim of the study was to investigate the effects of ω-3 PUFA on inflammation and on the expression of MMP-2 and -9 in a murine periodontitis model. Twenty-four male C57BL/6 mice were divided into control m ice (Control), control mice treated with ω-3 PUFA ...
Source: Odontology - January 1, 2024 Category: Dentistry Source Type: research

Correction to: Immunoexpression of SIRT1, 6, and 7 in oral leukoplakia and oral squamous cell carcinoma
(Source: Odontology)
Source: Odontology - January 1, 2024 Category: Dentistry Source Type: research

Deleterious effect of chronic high-dose ethanol intake on biomechanical bone properties and periodontal status
AbstractTo evaluate the effect of high-graduation chronic ethanol (EtOH) intake on bone and periodontal tissues of rats. Male Wistar rats (250  g) were divided into two groups ofn = 12 each one. EtOH (5 ml of 3 g/kg) was administered to the experimental group by gastric gavage twice a day for 20 days and the control group received water under the same conditions. The rats were euthanized and used to perform biochemical determination in plasma and gingival tissue, and histological and biomechanical studies in the femur and mandibular tissues. Alcohol increased both TNFα (p <  0.01) and PGE2 (p <  0.05...
Source: Odontology - December 29, 2023 Category: Dentistry Source Type: research

The effect of various surface treatments on the repair bond strength of denture bases produced by digital and conventional methods
This study aims to evaluate various surface treatments on flexural bond strength of repaired dentured base resins produced by digital and conventional methods. A total of 360 samples were prepared from one heat-polymerized, one CAD/CAM milled and one 3D printed denture base materials. All of the test samples were subjected to thermocycling (5 –55 °C, 5000 cycles) before and after repair with auto-polymerizing acrylic resin. The test samples were divided into five subgroups according to the surface treatment: grinding with silicon carbide (SC), sandblasting with Al2O3 (SB), Er:YAG laser (L), plasma (P) and negative cont...
Source: Odontology - December 29, 2023 Category: Dentistry Source Type: research

Effect of incorporation of calcium polyphosphate sub-microparticles in low-concentration bleaching gels on physical properties of dental enamel
ConclusionThe incorporation of CaPPs in low-concentration whitening gels reduces its negative effects on microhardness without interfering with their bleaching efficacy. (Source: Odontology)
Source: Odontology - December 26, 2023 Category: Dentistry Source Type: research

Comparison of the fracture strengths of single-unit metal-ceramic and monolithic zirconium restorations in the molar region: a systematic review and meta-analysis
AbstractDespite the success of monolithic zirconia restorations (MZ), metal-ceramic restorations (MC) are still considered the gold standard for fixed prosthetics in the posterior region. This systematic review and meta-analysis aimed to compare the fracture strengths of single-unit MC and MZ in the molar region. This review was based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA, 2020) statement. All articles were searched from the PubMed and Web of Science databases until November 18, 2022. All in vitro studies evaluating the fracture strengths of MC and MZ were also included. Statisti...
Source: Odontology - December 16, 2023 Category: Dentistry Source Type: research

Screw-in force, torque generation, and performance of glide-path files with three rotation kinetics
AbstractWe aimed to evaluate the screw-in force, torque generation, and performance of three nickel-titanium (NiTi) glide-path files with different rotational kinetics. ProTaper Ultimate Slider (PULS) and HyFlex EDM Glide-path (HEDG) files were used for canal shaping with constant rotation (CON) or the alternative rotation technique (ART). In the ART mode, the NiTi file was periodically rotated at a speed of 1.5 times faster than that in the CON mode. WaveOne Gold Glider was used with reciprocating motion (WOGG_RCP). Sixty J-shaped resin blocks were assigned to five groups: PULS_CON, PULS_ART, HEDG_CON, HEDG_ART, and WOGG_...
Source: Odontology - December 16, 2023 Category: Dentistry Source Type: research

Bulk-fill composite in challenging cavities: conversion rate, solubility, and water absorption analysis
AbstractIn a deep, curved cavity, polymerization of a bulk fill composite can be challenging. The aim of this study was to investigate the solubility, water absorption, and conversion rate of bulk-fill composite samples prepared using molds with various slope angles. Bulk-fill composite resin (Filtek One Bulk Fill) was placed into cylindrical Teflon molds with a depth of 4  mm, angled at varying degrees (90°, 75°, 60°, 45°). Two different LED light-curing units (VALO Cordless, iLed Curing Light) were used to cure the samples. Polymerizations were performed at three different distances (0 mm, 2 mm, and 4 mm). Five s...
Source: Odontology - December 12, 2023 Category: Dentistry Source Type: research

Impact of calcium hydroxide and 2-hydroxyisocaproic acid on the microhardness of root dentine: an in vitro study
AbstractTo evaluate and compare the effect of calcium hydroxide [Ca(OH)2] and 2-hydroxyisocaproic acid (HICA) on the microhardness of root dentine. Fifty-one matured maxillary central incisors with straight root and type I canal configuration were decoronated to a standardized length of 16  mm. The root canals were cleaned and shaped using rotary instruments up to size F5. The tooth samples were then randomly assigned into three groups (n = 17) based on the intracanal medicament placed. Group A: control group with no intracanal medicament, Group B: root canals placed with Ca(OH)2, and Group C: root canals placed with ...
Source: Odontology - December 12, 2023 Category: Dentistry Source Type: research

CXCL14 and miR-4484 serves as potential salivary biomarkers for early detection of peri-implantitis
AbstractPeri-implantitis develops in 43.3% of implant patients, which affects tissues around the implant that may ultimately cause implant loss if not treated properly. Due to difficulties in detecting peri-implantitis in its early phases, implant failures are constantly on the rise. Therefore, new specific molecular markers need to be identified to prevent or limit disease progression in peri-implantitis patients. We investigated levels of CXCL9, CXCL12, and CXCL14 in saliva samples of 45 patients with commercially pure grade 4/5 Titanium –Aluminum–Vanadium implants. We analyzed the correlation of the chemokine levels...
Source: Odontology - December 12, 2023 Category: Dentistry Source Type: research

Effect of heat application on the physicochemical properties of new endodontic sealers: an in vitro and SEM study
This study investigates the effect of heat on the physicochemical properties of new calcium silicate sealers, addressing concerns raised by clinicians seeking to combine their benefits with the gutta-percha obturation technique. Five endodontic sealers (AH Plus Bioceramic ®, Total Fill® BC®, One-fil® Bioceramic, K-Biocer, Any-seal®) were evaluated. Each sealer (n = 16/group) was either kept at 37 °C or subjected to heat at 60 or 200 °C for 30 s. ISO 6876-2012 standards were used to measure setting time, flow, film thickness, and dimensional changes over time. SEM and EDS were utilized for surface and chemical...
Source: Odontology - December 9, 2023 Category: Dentistry Source Type: research

Mechanical properties of simulated dentin caries treated with metal cations and l-ascorbic acid 2-phosphate
AbstractThis pH cycling study aimed to investigate the effects ofl-Ascorbic acid 2-phosphate (AA2P) salts of Mg, Zn, Mn, Sr, and Ba on the surface microhardness, compressive strength, diametral tensile strength (DTS), and solubility of root canal dentin. 186 cylindrical dentin specimens from 93 teeth were fortified with optimal concentrations of AA2P salts of Mg (0.18  mM), Zn (5.3 µM), Mn (2.2 × 10–8 M), Sr (1.8 µM), and Ba (1.9 µM). Saline was used as the control group. These dentin specimens underwent a 3-day cycling process simulating dentin caries formation through repeated sequences of demineralization...
Source: Odontology - November 17, 2023 Category: Dentistry Source Type: research

Characterization of the root and canal anatomy of maxillary premolar teeth in an Iraqi subpopulation: a cone beam computed tomography study
This study aims to evaluate the number of roots and root canal morphology types of maxillary premolars in relation to a patient ’s gender and age in an Iraqi population using two classification systems. Cone beam computed tomography (CBCT) scans of 1116 maxillary premolars from 385 patients were evaluated for the number of roots and root canal morphology types according to Vertucci’s classification and Ahmed et al. class ification systems. Differences in the number of roots and root canal morphology types with regard to tooth type, patients’ gender and age groups were evaluated and the degree of bilateral symmetry wa...
Source: Odontology - November 13, 2023 Category: Dentistry Source Type: research

The effect of bovine trypsin on dental biofilm dispersion: an in vitro study
AbstractTo investigate the degradation effect of bovine trypsin on multispecies biofilm of caries-related bacteria and provide an experimental foundation for the prevention of dental caries. Standard strains ofS.mutans,S. sanguis,S. gordonii, andL. acidophilus were co-cultured to form 24  h, 48 h, and 72 h biofilms. The experimental groups were treated with bovine trypsin for 30 s, 1 min, and 3 min. Morphological observation and quantitative analysis of extracellular polymeric substances (EPS), live bacteria, and dead bacteria were conducted using the confocal laser scanning m icroscope (CLSM). The morphological chan...
Source: Odontology - November 13, 2023 Category: Dentistry Source Type: research