Nuclear Medicine and Molecular Imaging This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Thyroglobulin-Based Risk Factor Repositioning for Determining Radioactive Iodine Activity in Patients with Papillary Thyroid Carcinoma: a Multicenter Retrospective Cohort Study
ConclusionRisk factors for response prediction could be repositioned based on the serum Tg before RAI therapy. RAI activity should be determined while considering the serum Tg-aided remnant thyroid or malignant tissues as well as conventional factors. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - June 18, 2022 Category: Nuclear Medicine Source Type: research

Interval Changes in PSMA PET/CT During Radium-223 Therapy for Metastatic Bone Disease from Castration-Resistant Prostate Cancer
ConclusionPSMA PET was able to assess response in individual lesions during radium-223 therapy in mCRPC patients. PSMA PET responses in previously established disease sites were universal, but most patients also showed overall PSMA PET progression during 6 cycles of radium-223. Given high correlation with changes in PSA, PSMA PET may be of limited value in follow-up during or after radium-223 in bone-predominant mCRPC.Graphical abstract (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - June 8, 2022 Category: Nuclear Medicine Source Type: research

99mTc-PSMA Left Behind: a Call for Collaboration
(Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - June 6, 2022 Category: Nuclear Medicine Source Type: research

68Ga-DOTATOC Embolus Manifestation and Spontaneous Resolution by PET/CT
Abstract68Ga-labeled somatostatin receptor analogs physiologic distribution patterns have become recognizable among nuclear medicine physicians because of the increasing routine clinical use of this modality in the work-up of neuroendocrine tumors. Some pitfalls during68Ga-labeled somatostatin receptor PET/CT have recently been reported as causes of misdiagnoses. Iatrogenic microembolism as a cause of18F-FDG embolus is well-established; however, 68Ga-DOTATOC embolus is not well documented in the literature. In the current case, the presence and the spontaneous resolution of the68Ga-labeled somatostatin receptor  analogs e...
Source: Nuclear Medicine and Molecular Imaging - May 12, 2022 Category: Nuclear Medicine Source Type: research

Automatic Lung Cancer Segmentation in [18F]FDG PET/CT Using a Two-Stage Deep Learning Approach
ConclusionThe proposed method will be useful for reducing the time and effort required for accurate lung cancer segmentation in [18F]FDG PET/CT. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - May 11, 2022 Category: Nuclear Medicine Source Type: research

Pretreatment 18F-FDG PET/CT-Derived Parameters in Predicting Clinical Outcomes of Locally Advanced Upper Third Esophageal Squamous Cell Carcinoma After Definitive Chemoradiation Therapy
ConclusionsOur study suggests that SUVmean of the primary tumor in pretreatment18F-FDG PET/CT may be used as an independent predictor in esophageal squamous cell carcinoma patients treated with definitive chemoradiotherapy. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - May 10, 2022 Category: Nuclear Medicine Source Type: research

Incidentally Found Soft Tissue 99mTc-DPD Uptake on Bone Scintigraphy Was Useful in an Early Diagnosis of Peripheral Arterial Disease
AbstractPeripheral arterial disease (PAD) is a critical disease which is presented by occlusion of peripheral arteries, while it could result in amputation of the involved limbs if it remained untreated before it would progress into tissue necrosis. It is usually diagnosed by CT angiography or conventional angiography, but its early diagnosis is challenging because its symptoms may be absent or like those of other diseases. In this case report, the authors showed that an atypical soft tissue uptake of lower limb incidentally found on a bone scintigraphy resulted in early diagnosis and successful treatment outcome of PAD. (...
Source: Nuclear Medicine and Molecular Imaging - April 25, 2022 Category: Nuclear Medicine Source Type: research

Technetium 99m PSMA Superscan Mimicking a Bone Scan Gone Wrong
We present a case of a 43-year-old male, who was referred to our facility for workup for radioligand PSMA therapy. His Tc-99m PSMA images revealed diffuse bone infiltration in a pattern mimicking a bone scan. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 19, 2022 Category: Nuclear Medicine Source Type: research

Prospective F-18 FDOPA PET Imaging Study in Human PD
ConclusionOur prospective study demonstrates high specificity and moderate sensitivity of F-18 FDOPA PET for PD. We received NDA approval in October 2019. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 12, 2022 Category: Nuclear Medicine Source Type: research

Infected Lower Limb Megaprosthesis on 68Ga-NOTA-Ubiquicidin PET/CT Imaging
We describe a case of a 24-year-old man with right lower limb megaprosthesis which did not show any loosening on computed tomography (CT) but was accurately diagnosed as infected prosthesis with68Ga-NOTA-ubiquicidin(29-41) acetate scan. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 11, 2022 Category: Nuclear Medicine Source Type: research

Experience of 6-l-[18F]FDOPA Production Using Commercial Disposable Cassettes and an Automated Module
ConclusionThe yields obtained are low and hence there is a need to improve synthetic chemistry. In order to understand the efficiency of each step, a detailed analysis using the radioactive traces obtained from the automated module was carried out. The radiolabeling yield of precursor is only about 50% and there is subsequent reduction in activity in the oxidation as well as hydrolysis steps. Despite the low radiochemical yields, the product obtained was suitable for imaging. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 6, 2022 Category: Nuclear Medicine Source Type: research

KSNM60: The History of Radiopharmaceutical Sciences in Korea
AbstractA number of researchers in Korea have tried to set-up the production of radionuclides and develop new radiopharmaceuticals for several decades. Thanks to their 60-year endeavor to advance the field of radiopharmaceutical sciences, now we have a lot of research units and facilities in Korea. Still, there are huge number of issues to be solved in radiopharmaceutical sciences; however, our efforts will be continued to develop new radiopharmaceuticals and to apply the new radiopharmaceuticals into nuclear medicine field. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 5, 2022 Category: Nuclear Medicine Source Type: research

68Ga-DOTA-RGD2 Uptake in Plantar Fasciitis: New Insights into its Pathogenesis
AbstractPlantar fasciitis is chronic degenerative tendinopathy of the plantar fascia. Although it has many treatment modalities, none has been very effective due to the largely unknown pathogenesis of this condition.68Ga-DOTA-RGD2 has an upcoming role in assessing disease activity and treatment response in rheumatoid arthritis. In the present case, we demonstrate the potential role of angiogenesis imaging in understanding the pathogenesis of plantar fasciitis and provide new opportunities for novel imaging options. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 5, 2022 Category: Nuclear Medicine Source Type: research

[64Cu]Cu-Albumin Clearance Imaging to Evaluate Lymphatic Efflux of Cerebrospinal Space Fluid in Mouse Model
ConclusionsWe established molecular imaging to evaluate CSF drainage through mLV using [64Cu]Cu-HSA. This imaging method is expected to be extended in animal models of dysfunctional meningeal lymphatic clearance and translational research for disease-modifying therapeutic approaches. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 2, 2022 Category: Nuclear Medicine Source Type: research

Clinical Use of Radiopharmaceuticals in Boron Neutron Capture Therapy
(Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - March 14, 2022 Category: Nuclear Medicine Source Type: research