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Change of Therapeutic Response Classification According to Recombinant Human Thyrotropin-Stimulated Thyroglobulin Measured at Different Time Points in Papillary Thyroid Carcinoma
ConclusionD1Tg measurement was sufficient to assess the therapeutic response in most patients with low level of D1Tg. Nevertheless, D2-3Tg measurement was still necessary in the patients with D1Tg higher than a certain level as response classification based on D2-3Tg could change. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 29, 2021 Category: Nuclear Medicine Source Type: research

One Versus Up-to-5 Lesion Measurements for Response Assessment by PERCIST in Patients with Lung Cancer
ConclusionAnalyzing 1 lesion and up-to-5 lesions for response assessment by PERCIST showed high concordance in patients with lung cancer. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 27, 2021 Category: Nuclear Medicine Source Type: research

Extended Whole-body Ga-68 DOTATATE PET-CT in evaluating Tumour-Induced Osteomalacia: Case report and review of literature
AbstractTumour-induced osteomalacia is a rare paraneoplastic syndrome that manifests as chronic hypophosphataemia, non-specific bone pain and muscle weakness. It is generally caused by phosphaturic mesenchymal tumour (PMT), which is uncommonly associated with synchronous tumours. However, diagnosis is often delayed for several years due to the rarity, indolent growing nature and non-specific symptoms of the disease, often resulting in an overlook by clinicians during assessments. The patient initially presented with hypophosphataemia and generalised skeletal pain with multiple atraumatic fractures. Blood tests revealed ser...
Source: Nuclear Medicine and Molecular Imaging - April 19, 2021 Category: Nuclear Medicine Source Type: research

The Outcome and Safety of Re-challenge Lutetium-177 PSMA ( 177 Lu-PSMA) Therapy with Low-Dose Docetaxel as a Radiosensitizer —a Promising Combination in Metastatic Castrate-Resistant Prostate Cancer (mCRPC): a Case Report
We report the use of low-dose Taxol-based chemotherapy (modified dose 25  mg/m2 weekly  × 6 weeks) as a radiosensitizer with re-challenge177Lu-PSMA therapy (4 cycles). In a period of 3  years, the patient underwent a total of 8 cycles of177Lu-PSMA with a cumulative dose of 51.8  GBq. All therapies were uneventful and well tolerated. There was a good response to re-challenge177Lu-PSMA therapy and low-dose docetaxel (Taxol-177Lu-PSMA) with no recorded tumour resistance. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 13, 2021 Category: Nuclear Medicine Source Type: research

Correction to: Recent Progress in the Molecular Imaging of Tumor-Treating Bacteria
A Correction to this paper has been published:https://doi.org/10.1007/s13139-021-00694-7 (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 12, 2021 Category: Nuclear Medicine Source Type: research

KSNM 60 years: International Collaboration with Asian Nuclear Medicine Community
(Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - April 2, 2021 Category: Nuclear Medicine Source Type: research

Quantification of Hypoxia in Human Glioblastoma using PET with 18F-FMISO
ConclusionBased on these results, the combination of CM and SA approaches was found more appropriate in generating voxel-based hypoxia images. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - March 25, 2021 Category: Nuclear Medicine Source Type: research

Angiogenesis-Targeted 68 Ga-DOTA-RGD 2 PET/CT Imaging: a Potential Theranostic Application in the Case of Chondrosarcoma
We present a case of a 53-year-old man with grade II chondrosarcoma of the left femur showing only mild avidity on18F-FDG PET/CT but showing moderate to intense tracer avidity on68Ga-DOTA-RGD2 PET/CT. This may enable the use of angiogenesis-targeted positron and beta-emitting radiopharmaceuticals as a potentially new theranostic alternative treatment in cases of refractory metastatic chondrosarcoma. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - March 16, 2021 Category: Nuclear Medicine Source Type: research

A 4-Year Follow-Up of Subjects with Visually Equivocal Amyloid Positron Emission Tomography Findings from the Alzheimer ’s Disease Neuroimaging Initiative Cohort
ConclusionApproximately 8% of subjects from the ADNI cohort showed visually equivocal amyloid PET scans with intermediate load and rapid accumulation of amyloid, but did not convert to AD during the 4-year follow-up. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - March 4, 2021 Category: Nuclear Medicine Source Type: research

Hilar Choledochal Cyst Mimicking Biliary Atresia on Hepatobiliary Scintigraphy: a Case Report
AbstractHepatobiliary scintigraphy has been widely used for the differential diagnosis of neonatal cholestasis. Relatively good hepatic uptake with no evidence of excretion into the bowel for up to 24 h is a representative finding of biliary atresia. Hepatobiliary scintigraphy has very high sensitivity and moderate specificity. Here, we report a false-positive case of hepatobiliary scintigraphy in a child with a choledochal cyst, which mimicked biliary atresia. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - February 17, 2021 Category: Nuclear Medicine Source Type: research

High-Efficiency Cationic Labeling Algorithm of Macroaggregated Albumin with 68 Gallium
ConclusionsThe radiochemical and chemical purity of the final product allows direct use without purification steps to remove “free68Ga ” or other toxic compounds. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - February 10, 2021 Category: Nuclear Medicine Source Type: research

Imaging Characteristics of Brain SPECT, PET, and MRI in Neurosyphilis
We report brain MRI, SPECT with Tc-99m ECD, and PET with F-18 FDG findings before antibiotic therapy in a neurosyphilis patient with neurological symptoms. The cerebral cortices showed hypoperfusion with a patchy distribution on SPECT and foci with high signal intensity on MRI, suggesting ischemia. Brain PET showed areas with hypometabolism in the temporoparietal lobes bilaterally. (Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - February 6, 2021 Category: Nuclear Medicine Source Type: research

Message from the New Editor-in-Chief
(Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - February 2, 2021 Category: Nuclear Medicine Source Type: research

Short Essay on 60  Years’ Challenges and Achievements of KSNM
(Source: Nuclear Medicine and Molecular Imaging)
Source: Nuclear Medicine and Molecular Imaging - February 1, 2021 Category: Nuclear Medicine Source Type: research

Recent Progress in the Molecular Imaging of Tumor-Treating Bacteria
AbstractBacterial cancer therapy (BCT) approaches have been extensively investigated because bacteria can show unique features of strong tropism for cancer, proliferation inside tumors, and antitumor immunity, while bacteria are also possible agents for drug delivery. Despite the rapidly increasing number of preclinical studies using BCT to overcome the limitations of conventional cancer treatments, very few BCT studies have advanced to clinical trials. In patients undergoing BCT, the precise localization and quantification of bacterial density in different body locations is important; however, most clinical trials have us...
Source: Nuclear Medicine and Molecular Imaging - January 31, 2021 Category: Nuclear Medicine Source Type: research