Exploring Cognitive Concomitants of Mental Fatigue in Patients with Coronary Artery Disease
Conclusion: In rehabilitating CAD patients, certain aspects of executive functioning were independently associated with mental fatigue. These findings suggest that the subjective experience of mental fatigue, rather than reduced exercise capacity, is significantly associated with cognitive function.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 25, 2018 Category: Psychiatry & Psychology Source Type: research
Association of Plasma Cortisol Levels with Clinical Characteristics of Suicide Attempters
Conclusions: Certain clinical characteristics were identified in attempters with low cortisol levels. In previous studies, low cortisol levels have been associated with impairments in cognitive control, decision-making, and emotional processing that may lead, in the presence of stressors, to suicidal behavior, frequently with non-fatal outcome. Adding plasma cortisol levels to demographic and psychopathological data may help in identifying a subpopulation of attempters with neurocognitive deficits linked to dysfunction of Hypothalamic-Pituitary-Adrenal-axis activity, with implications for treatment.Neuropsychobiology (Sour...
Source: Neuropsychobiology - June 25, 2018 Category: Psychiatry & Psychology Source Type: research
Association of Brain-Derived Neurotrophic Factor and Vitamin D with Depression and Obesity: A Population-Based Study
Conclusion: Vitamin D was inversely associated with depression and obesity. BDNF was associated with abdominal obesity, but not with depression. At the population level, our results support the relevant roles of vitamin D and BDNF in mental and physical health-related outcomes.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 19, 2018 Category: Psychiatry & Psychology Source Type: research
Salivary Inflammatory Markers in Trichotillomania: A Pilot Study
Conclusions: The relatively low level of inflammatory saliva cytokines observed in the current study (negative z scores versus normative data with medium effect sizes) indicates that evaluation of blood inflammatory levels in trichotillomania versus matched controls would be valuable in future work. If a hypoinflammatory state is confirmed using blood samples, this would differentiate trichotillomania from other mental disorders (such as OCD, schizophrenia, and depression), which have typically been linked with high inflammatory measures in the literature, at least in some cases.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 19, 2018 Category: Psychiatry & Psychology Source Type: research
IPEG Society News
Neuropsychobiology 2017;76:116 –116 (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 14, 2018 Category: Psychiatry & Psychology Source Type: research
Association between Elevated C-Reactive Protein and Manic Polarity in Acute Psychiatric Inpatients with Affective Symptomatology
The interplay between the immune system and behaviour is of increasing interest in psychiatry research. Specifically, accumulating data points to a link between inflammation and psychopathology, including affective symptomatology. We investigated the association between inflammation and affective polarity in psychiatric inpatients who were hospitalized due to an affective exacerbation. Data was collected retrospectively and comparisons were made between manic and depressed patients. C-reactive protein (CRP), a general laboratory marker of immune activation and inflammation, was used as a non-specific inflammatory biomarker...
Source: Neuropsychobiology - June 14, 2018 Category: Psychiatry & Psychology Source Type: research
Pathophysiology of Depression: Molecular Regulation of Melatonin Homeostasis – Current Status
Circadian rhythm alterations resulting in disturbed sleep and disturbed melatonin secretion are flagship features of depression. Melatonin, known as a hormone of darkness, is secreted by the pineal gland located near to the center of the brain between the two hemispheres. Melatonin has an antidepressant effect by maintaining the body ’s circadian rhythm, by regulating the pattern of expression of the clock genes in the suprachiasmatic nucleus (SCN) and modifying the key genes of serotoninergic neurotransmission that are linked with a depressive mood. Melatonin is produced via the metabolism of serotonin in two steps whic...
Source: Neuropsychobiology - June 13, 2018 Category: Psychiatry & Psychology Source Type: research
Abstracts of Award-Winning Posters, 17th International Forum on Mood and Anxiety Disorders, Madrid, December 14 –16, 2017
Neuropsychobiology 2017;76:47 –50 (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 12, 2018 Category: Psychiatry & Psychology Source Type: research
Chronobiology: Society for Light Treatment and Biological Rhythms, 30th Annual Meeting, Groningen (The Netherlands), June 21 –24, 2018
Neuropsychobiology 2017;76:1 –46 (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 12, 2018 Category: Psychiatry & Psychology Source Type: research
The Effects of a < b > < i > BDNF < /i > < /b > Val66Met Polymorphism on Posttraumatic Stress Disorder: A Meta-Analysis
Conclusions: Findings from this meta-analytic investigation of the published literature provide little support for the Val66Met variant ofBDNF as a predictor of PTSD. Future well-powered agnostic genome-wide association studies with more refined phenotyping are needed to clarify genetic influences on PTSD.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 6, 2018 Category: Psychiatry & Psychology Source Type: research
Physiological Differences in the Follicular, Luteal, and Menstrual Phases in Healthy Women Determined by Electrovestibulography: Depression, Anxiety, or Other Associations?
This study ’s objectives were to: (1) extract EVestG features representing physiological differences of healthy women during their menses, and follicular and luteal phases of their menstrual cycle, and (2) compare these features to those observed in previous studies for depression with and without anxiety. T hree EVestG recordings were made on 15 young healthy menstruating females during menses, and follicular and luteal phases. Three features were extracted, using the shape and timing of the detected spontaneously evoked vestibulo-acoustic field potentials. Using these features, a 3-way separation of t he 3 phases was a...
Source: Neuropsychobiology - June 5, 2018 Category: Psychiatry & Psychology Source Type: research
Changes in Gene Expression Profiles in Adult Rat Brain Structures after Neonatal Action of Dipeptidyl Peptidase-IV Inhibitors
In this study, using real-time PCR, we evaluated changes in the gene expression of serine protease DPP-IV and prolyl endopeptidase (PREP, EC 3.4.21.26;dpp4 andprep genes), monoamine oxidase А (maoA) and B (maoB), and serotonin transporter (SERT;sert) in the brain structures from 3-month-old rats after postnatal action of DPP-IV inhibitors diprotin A and sitagliptin.Results:Dpp4,sert, andmaoB gene expression increased andmaoA gene expression changed with a tendency to increase in the striatum of rats with neonatal sitagliptin action. The increase ofmaoA gene expression was also shown in the amygdala. An increase inprep gen...
Source: Neuropsychobiology - June 1, 2018 Category: Psychiatry & Psychology Source Type: research
Twenty Years After: Another Case Report of Melatonin Effects on REM Sleep Behavior Disorder, Using Serial Dopamine Transporter Imaging
Discussion: To the best of our knowledge, DA transporter density increase over time has never been reported in a single subject, neither healthy aged individuals nor patients suffering from RBD or PD. We interpret these results as a possible neuroprotective role for melatonin in synucleinopathy.Neuropsychobiology 2017;76:100 –104 (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 1, 2018 Category: Psychiatry & Psychology Source Type: research
Corticolimbic Connectivity Mediates the Relationship between Adverse Childhood Experiences and Symptom Severity in Borderline Personality Disorder
The interaction between biological and environmental factors (especially adverse childhood experiences, ACEs) plays a crucial role in the development and maintenance of borderline personality disorder (BPD). These factors act influencing BPD core features such as pervasive instability in affect regulation, impulse control, social cognition, and interpersonal relationships. In line with this perspective, abnormalities in social cognition and related neurobiological underpinnings could mediate the relationship between ACEs and psychopathological manifestations in adulthood. In a sample of 14 females, functional connectivity ...
Source: Neuropsychobiology - June 1, 2018 Category: Psychiatry & Psychology Source Type: research
Chronobiology
Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - May 29, 2018 Category: Psychiatry & Psychology Source Type: research
