The Many Faces of Sleep Disorders in Post-Traumatic Stress Disorder: An Update on Clinical Features and Treatment
Sleep disorders and nightmares are core symptoms of post-traumatic stress disorder (PTSD). The relationship seems to be bidirectional, and persistent disturbed sleep may influence the course of the disorder. With regard to sleep quality, insomnia and nocturnal anxiety symptoms, as well as nightmares and stressful dreams, are the most prominent sleep symptoms. Polysomnographic measurements reveal alterations of the sleep architecture and fragmentation of rapid eye movement sleep. In addition, sleep disorders, such as sleep-related breathing disorders and parasomnias are frequent comorbid conditions. The complex etiology and...
Source: Neuropsychobiology - September 2, 2021 Category: Psychiatry & Psychology Source Type: research
The Effect of a Probiotic Complex on the Gut-Brain Axis: A Translational Study
Conclusions: According to the results,L. reuteri PBS072 andB. breve BB077 are potential probiotic candidates for improving stress resilience, cognitive functions, and sleep quality.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - August 30, 2021 Category: Psychiatry & Psychology Source Type: research
Dysfunctional Overnight Memory Consolidation in Patients with Schizophrenia in Comparison to Healthy Controls: Disturbed Slow-Wave Sleep as Contributing Factor?
Conclusion: As expected, schizophrenia patients showed deficient overnight verbal declarative memory consolidation as compared to healthy controls. Reduced sleep spindles, delta power, and spindle power during the SO up-state may link sleep and memory deficiency in schizophrenia. Additionally, the absence of a linear relationship between sleep-related memory consolidation and slow-wave sleep as well as delta power suggests further functional impairments in schizophrenia. Note that this conclusion is based on observational data. Future studies should investigate if stimulation of delta waves during sleep could improve memor...
Source: Neuropsychobiology - August 25, 2021 Category: Psychiatry & Psychology Source Type: research
Neuroinflammation in Late-Onset Schizophrenia: Viewing from the Standpoint of the Microglia Hypothesis
Schizophrenia develops mainly in adolescence, but late-onset schizophrenia (LOS) is not uncommon. According to the international consensus, schizophrenia which develops over 40 years old is called LOS and psychosis which develops over 60 years old is called very late-onset schizophrenia-like psychosis (VLOS). Compared to early-onset schizophrenia (EOS) that develops before the age of 40 years, LOS and VLOS are reported to be more common in women, and there are clinically clear differences such as less involvement of genetic factors than EOS. This review outlines the abnormalities of the neuroimmune system in the pathophysi...
Source: Neuropsychobiology - August 6, 2021 Category: Psychiatry & Psychology Source Type: research
Changes in Electric Brain Response to Affective Stimuli in the First Week of Antidepressant Treatment: An Exploratory Study
Discussion: Our study addresses the gap in comparisons of task-related EEG activity changes measured at two time points and supports the potential value of this approach in detecting early differences in responders versus nonresponders to pharmacological treatment. Important limitations include the small sample size and the noncontrolled study design.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - August 5, 2021 Category: Psychiatry & Psychology Source Type: research
Dysregulated Diurnal Cortisol Pattern and Heightened Night-Time Cortisol in Individuals with Bipolar Disorder
Conclusion: Significantly higher levels of cortisol in participants with BD in the night-time suggest that the attenuation of cortisol observed in healthy individuals may be impaired in those with BD. Reregulation of cortisol levels may be a target of further study and treatment intervention for individuals with BD.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - July 28, 2021 Category: Psychiatry & Psychology Source Type: research
Comparative Efficacy and Acceptability of 3 Repetitive Transcranial Magnetic Stimulation Devices for Depression: A Meta-Analysis of Randomized, Sham-Controlled Trials
Conclusion: Our results suggest similar efficacy and acceptability for the 3 stimulation devices. Future studies need to perform head-to-head comparisons of the efficacy and acceptability of the stimulation devices for treating depression using the same stimulation protocols.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - July 28, 2021 Category: Psychiatry & Psychology Source Type: research
Fever as a Side Effect after Electroconvulsive Therapy
Conclusion: Comparing fever and control sessions, fever sessions relatively preceded control sessions and had a longer seizure duration. Postictal delirium occurred more often in the fever sessions than in control sessions. Fever sessions had a higher white blood cell count and lower concomitant quetiapine dosage than control sessions. Because 8.8% of patients who received ECT experienced fever after treatment more than once, fever after ECT is considered to be a common side effect.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - July 7, 2021 Category: Psychiatry & Psychology Source Type: research
White Matter Hyperintensities after Five-Year Follow-Up and a Cross-Sectional FA Decrease in Bipolar I and Major Depressive Patients
Conclusions: Preceding illness burden associated modestly with WMHs, and FA increase in RCMP in BPI patients. MDD patients had FA decrease in RCMP. No association with FA decrease and WMHs was found.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - June 15, 2021 Category: Psychiatry & Psychology Source Type: research
Antibodies against N-Methyl D-Aspartate Receptor in Psychotic Disorders: A Systematic Review
Conclusions: NMDAR ABs are definitely present in a subset of psychotic patients. NMDAR ABs might shape psychosis and underlie some symptoms, and immunotherapy might be regarded as a treatment option for patients failing to respond to other therapies.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - May 17, 2021 Category: Psychiatry & Psychology Source Type: research
Neuroprotective and Antioxidant Effects of Riparin I in a Model of Depression Induced by Corticosterone in Female Mice
Conclusion: These findings suggest that RIP I can be a strong candidate for drugs in the treatment of depression.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - April 29, 2021 Category: Psychiatry & Psychology Source Type: research
Inflammatory Markers May Inform the Effects of Electroconvulsive Therapy on Cognition in Patients with Depression
Conclusion: Our findings tentatively suggest that the effects of ECT on verbal episodic memory may be related to the treatment ’s immunomodulatory properties, most notably due to decreased IL-6 levels. Moreover, baseline IL-10 appears to be a potential biomarker to predict the effects of ECT on verbal episodic memory. Whilst compelling, the results of this study should be interpreted with caution as, due to its explorator y nature, no correction for multiple comparisons was made. Further, a replication in larger cohorts is warranted.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - April 28, 2021 Category: Psychiatry & Psychology Source Type: research
Augmentation of Psychotherapy with Neurobiological Methods: Current State and Future Directions
Conclusions: This approach provides an open matrix for further research and has the potential to systematically guide future studies.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - April 28, 2021 Category: Psychiatry & Psychology Source Type: research
Does Physical Activity Improve Cognition and Academic Performance in Children? A Systematic Review of Randomized Controlled Trials
Conclusions: Although grouping different studies based on PA type, control groups, and comparison treatments is a limitation and results should be interpreted with caution, this review suggests that PA interventions, in particular, team game variations and coordination activities, have positive effects on children ’s cognitive functions.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - April 22, 2021 Category: Psychiatry & Psychology Source Type: research
Title Page / Table of Contents
Neuropsychobiology 2021;80:75 –77 (Source: Neuropsychobiology)
Source: Neuropsychobiology - April 15, 2021 Category: Psychiatry & Psychology Source Type: research
