Recurrence of Depression in Relation to History of Childhood Trauma and Hair Cortisol Concentration in a Community-Based Sample
Conclusions: Our findings show that retrospectively reported childhood trauma is associated with protracted trajectories of depression and a distinct pattern of long-term HPA axis activity.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - March 21, 2019 Category: Psychiatry & Psychology Source Type: research
Stress-Induced Release of Eating-Related Hormones in Young Women Classified as Restrained and Unrestrained Eaters
Conclusion: Restrained eaters suffer from a possible stress-related biological dysregulation of eating, posing them at risk for eating and weight disorders.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - March 20, 2019 Category: Psychiatry & Psychology Source Type: research
20th Biennial IPEG Meeting 2018 in Z ürich
Neuropsychobiology 2018/2019;77:117 –118 (Source: Neuropsychobiology)
Source: Neuropsychobiology - March 7, 2019 Category: Psychiatry & Psychology Source Type: research
Abstracts
Neuropsychobiology 2018/2019;77:119 –162 (Source: Neuropsychobiology)
Source: Neuropsychobiology - March 7, 2019 Category: Psychiatry & Psychology Source Type: research
Title pages
Neuropsychobiology 2018/2019;77:111 –116 (Source: Neuropsychobiology)
Source: Neuropsychobiology - March 7, 2019 Category: Psychiatry & Psychology Source Type: research
Tryptophan Metabolism and Related Pathways in Psychoneuroimmunology: The Impact of Nutrition and Lifestyle
In the past, accelerated tryptophan breakdown was considered to be a feature of clinical conditions, such as infection, inflammation, and malignant disease. More recently, however, the focus has changed to include the additional modulation of tryptophan metabolism by changes in nutrition and microbiota composition. The regulation of tryptophan concentration is critical for the maintenance of systemic homeostasis because it integrates essential pathways involved in nutrient sensing, metabolic stress response, and immunity. In addition to tryptophan being important as a precursor for the synthesis of the neurotransmitter ser...
Source: Neuropsychobiology - February 26, 2019 Category: Psychiatry & Psychology Source Type: research
Electroencephalography in Neuropsychiatric Disorders: Microstates, LORETA, and Mismatch Negativity – Homage to Dietrich Lehmann
Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - February 26, 2019 Category: Psychiatry & Psychology Source Type: research
The Effects of Probiotics on Symptoms of Depression: Protocol for a Double-Blind Randomized Placebo-Controlled Trial
Conclusions: The findings from this study will add to the growing body of research in this emerging field, which eventually may provide evidence for probiotics having a role in alleviating symptoms of depression.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - February 14, 2019 Category: Psychiatry & Psychology Source Type: research
Validity of Commonly Used Heart Rate Variability Markers of Autonomic Nervous System Function
Conclusions: Neither LF (in ms2 or normalized units [nu]) nor VLF represent cardiac sympathetic modulation of the heart. LF (ms2) may reflect vagally mediated baroreflex cardiac effects. HRV linear analysis therefore appears to be restricted to the determination of vagal influences on heart rate. With regard to HRV parasympathetic markers, this study supports the suggestion that HRV frequency domain analyses, such as HF, should not be used as an index of vagal activity in study tasks where verbal responses are required, as these responses may induce respiratory changes great enough to distort HF power.Neuropsychobiology (S...
Source: Neuropsychobiology - February 5, 2019 Category: Psychiatry & Psychology Source Type: research
Could Dietary Glutamate Play a Role in Psychiatric Distress?
Glutamate is an amino acid that functions as an excitatory neurotransmitter. It has also been associated with somatic and psychiatric distress and is implicated in the pathophysiology of psychiatric disorders such as schizophrenia. Ingestion of dietary glutamate, such as monosodium glutamate (MSG), has been mechanistically linked with greater distress among patients with chronic pain conditions, though findings have been equivocal. Preliminary research suggests that an MSG-restricted diet confers beneficial effects on somatic symptoms and well-being for some individuals with chronic pain conditions. In addition to associat...
Source: Neuropsychobiology - January 31, 2019 Category: Psychiatry & Psychology Source Type: research
EEG Resting-State Networks in Dementia with Lewy Bodies Associated with Clinical Symptoms
Conclusion: These results indicate that eLORETA-ICA can detect EEG-RSN activity alterations in DLB related to symptoms. Therefore, eLORETA-ICA with EEG data can be a useful noninvasive tool for sensitive detection of EEG-RSN activity changes characteristic of DLB and for understanding the neurophysiological mechanisms underlying this disease.Neuropsychobiology (Source: Neuropsychobiology)
Source: Neuropsychobiology - January 17, 2019 Category: Psychiatry & Psychology Source Type: research
Automated Source Estimation of Scalp EEG Epileptic Activity Using eLORETA Kurtosis Analysis
In this study, we focused on the evaluation of the reliability of eLORETA kurtosis analysis. For th is purpose, the results of eLORETA kurtosis source localization of paroxysmal activity in EEG were compared with those of eLORETA current source density (CSD) analysis of EEG data in 3 epilepsy patients with partial seizures.Methods: EEG was measured using a digital EEG system with 19 channels. We set the bandpass filter at traditional frequency band settings (1 –4, 4–8, 8–15, 15–30, and 30–60 Hz) and 5–10 and 20–70 Hz and performed eLORETA kurtosis to compare the source localization of paroxysmal activity with...
Source: Neuropsychobiology - January 13, 2019 Category: Psychiatry & Psychology Source Type: research
Role of Hypothalamic-Pituitary-Adrenal Axis, Hypothalamic-Pituitary-Gonadal Axis and Insulin Signaling in the Pathophysiology of Alzheimer ’s Disease
Alzheimer ’s disease (AD), the commonest progressive neurodegenerative disorder of the brain, is clinically characterized by the formation of extracellular amyloid plaques and intracellular neurofibrillary tangles. Recent studies suggest a relationship between the endocrinal dysregulation and the neuronal l oss during the AD pathology. Dysregulation of the hypothalamic-pituitary-adrenal (HPA) axis and hypothalamic-pituitary-gonadal (HPG) axis regulating circulating levels of glucocorticoid hormones has been implicated in the pathophysiology of AD. Likewise, dysregulated insulin signaling, impaired gluc ose uptake and ins...
Source: Neuropsychobiology - January 3, 2019 Category: Psychiatry & Psychology Source Type: research
Influence of Chronic Coenzyme Q10 Supplementation on Cognitive Function, Learning, and Memory in Healthy and Diabetic Middle-Aged Rats
Diabetes mellitus can induce impairment in learning and memory. Cognitive and memory deficits are common in older adults and especially in those with diabetes. This is mainly because of hyperglycemia, oxidative stress, and vascular abnormalities. Coenzyme Q10 (CoQ10) can decrease oxidative stress, hyperglycemia, and inflammatory markers, and improve vascular function. Therefore, the aim of the present study was to investigate the possible effects of CoQ10 on cognitive function, learning, and memory in middle-aged healthy and diabetic rats. Adult middle-aged male Wistar rats (390 –460 g, 12–13 months old) were divided i...
Source: Neuropsychobiology - December 21, 2018 Category: Psychiatry & Psychology Source Type: research
Corrected QT Interval Prolongation in Psychopharmacological Treatment and Its Modulation by Genetic Variation
Several antipsychotics and antidepressants have been associated with electrocardiogram alterations, the most clinically relevant of which is the heart rate-corrected QT interval (QTc) prolongation, a risk factor for sudden cardiac death. Genetic variants influence drug-induced QTc prolongation and can provide valuable information for precision medicine. The effect of genetic variants on QTc prolongation as well as the possible interaction between polymorphisms and risk medications in determining QTc prolongation were investigated. Medications were classified according to their known risk of inducing QTc prolongation (high-...
Source: Neuropsychobiology - December 13, 2018 Category: Psychiatry & Psychology Source Type: research
