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Effects of High ‐Voltage Pulsed Radiofrequency on the Ultrastructure and Nav1.7 Level of the Dorsal Root Ganglion in Rats With Spared Nerve Injury
ConclusionsThe HV-PRF produces a better analgesic effect than SV-PRF applied to the DRG in SNI rats. The underlying mechanisms may be associated with improving the histopathological prognosis and the downregulation of Nav1.7 levels in the DRG. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - September 6, 2021 Category: Biotechnology Authors: Zhisen Dai, Xueru Xu, Yanqin Chen, Chun Lin, Fan Lin, Rongguo Liu Tags: Basic Research Source Type: research

A Comprehensive Review of Vagus Nerve Stimulation for Depression
ConclusionsThe mood effects of VNS were discovered from clinical trials investigating the use of VNS for reducing seizures in epileptic patients. Since then, VNS has gone on to be FDA approved for depression. The field of VNS is growing, and as noninvasive VNS quickly advances, it is important to consider a historical perspective to develop future brain stimulation therapies. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - September 6, 2021 Category: Biotechnology Authors: Christopher W. Austelle, Georgia H. O'Leary, Sean Thompson, Elise Gruber, Alex Kahn, Andrew J. Manett, Baron Short, Bashar W. Badran Tags: Review Article Source Type: research

Pulsed Electromagnetic Fields: A Novel Attractive Therapeutic Opportunity for Neuroprotection After Acute Cerebral Ischemia
ConclusionsAltogether, these data demonstrate the efficacy of PEMFs against several mechanisms underlying ischemic damage and suggest that PEMFs might represent a novel noninvasive adjunctive treatment for acute ischemic stroke, providing neuroprotection and reducing functional deficits following ischemia. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - September 5, 2021 Category: Biotechnology Authors: Fioravante Capone, Simona Salati, Fabrizio Vincenzi, Micaela Liberti, Giorgio Aicardi, Francesca Apollonio, Katia Varani, Ruggero Cadossi, Vincenzo Di Lazzaro Tags: Review Article Source Type: research

Low Intensity Focused Ultrasound Increases Duration of Anti ‐Nociceptive Responses in Female Common Peroneal Nerve Injury Rats
ConclusionsNeuromodulation with liFUS has a greater effect in female rats on CPN latency, mechanical allodynia duration, and depression-like behavior. In order to customize neuromodulatory techniques for different patient phenotypes, it is essential to understand how they may alter sex-specific pathophysiologies. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - September 3, 2021 Category: Biotechnology Authors: Andrea Liss, Abigail Hellman, Vraj J. Patel, Teresa Maietta, Kanakaharini Byraju, Rachel Trowbridge, Jenica Acheta, Drishti Panse, Adithya Srikanthan, Paul Neubauer, Clif Burdette, Goutam Ghoshal, Emery Williams, Jiang Qian, Julie G. Pilitsi Tags: Basic Research Source Type: research

Low Intensity Focused Ultrasound Increases Duration of Anti ?Nociceptive Responses in Female Common Peroneal Nerve Injury Rats
ConclusionsNeuromodulation with liFUS has a greater effect in female rats on CPN latency, mechanical allodynia duration, and depression-like behavior. In order to customize neuromodulatory techniques for different patient phenotypes, it is essential to understand how they may alter sex-specific pathophysiologies. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - September 2, 2021 Category: Biotechnology Authors: Andrea Liss, Abigail Hellman, Vraj J. Patel, Teresa Maietta, Kanakaharini Byraju, Rachel Trowbridge, Jenica Acheta, Drishti Panse, Adithya Srikanthan, Paul Neubauer, Clif Burdette, Goutam Ghoshal, Emery Williams, Jiang Qian, Julie G. Pilitsi Tags: Basic Research Source Type: research

Calendar of Events
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Tags: Professional Development Source Type: research

Table of Contents
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Tags: Issue Information – Table of Contents Source Type: research

Aims and Scope
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Tags: Issue Information – Aims and Scope Source Type: research

Editorial Board
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Tags: Issue Information – Editorial Board Source Type: research

Peripheral Nerve Stimulation for Treatment of Severe Refractory Upper Extremity Post ‐Amputation Pain
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Michael J. Jung, Scott G. Pritzlaff Tags: Letter to the Editor Source Type: research

Scope for Vagus Nerve Stimulation in Traumatic Brain Injury
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Ashwin Kumaria, Christos M. Tolias Tags: Letter to the Editor Source Type: research

A Longitudinal Approach to Stimulation at the C2 ‐3 Medial Branches Over Lamina to Relieve Occipital Neuralgia: Case Report
(Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Anna Woodbury Tags: Letter To The Editor Source Type: research

The Predictive Value of Transcutaneous Electrical Nerve Stimulation for Patient Selection in Peripheral Nerve Field Stimulation for Chronic Low Back Pain: A Prospective Study
ConclusionTENS can be predictive for patient selection in PNFS, as TENS positive patients showed significant correlation with a positive PNFS trial period. Therefore, TENS positive patients might be justifiable to be directly implanted with leads and IPG. TENS positive patients further tend to show a better improvement in the follow-up. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Frank Patrick Schwarm, Marc Ott, Jasmin Nagl, Michael Bender, Marco Stein, Eberhard Uhl, Hagen Maxeiner, Malgorzata A. Kolodziej Tags: Clinical Research Source Type: research

Short ‐Term Peripheral Nerve Stimulation Relieve Pain for Elder Herpes Zoster Ophthalmicus Patients: A Retrospective Study
ConclusionsShort-term PNS is an effective and safe therapeutic alternative for elder patients with HZ ophthalmicus and could reduce the incidence of ophthalmic PHN. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Cheng ‐fu Wan, Tao Song Tags: Clinical Research Source Type: research

Pudendal Nerve Block by Low ‐Frequency (≤1 kHz) Biphasic Electrical Stimulation
ConclusionThis study discovered that LFBS ( ≤1 kHz), like high-frequency (≥5 kHz) biphasic stimulation (HFBS), can induce poststimulation block. The result provides support for the theory that biphasic stimulation waveforms block axonal conduction by changing intracellular and extracellular ion concentrations. The post-LFBS block provid es the opportunity to develop new neuromodulation devices for clinical applications where initial nerve firing is acceptable. (Source: Neuromodulation: Technology at the Neural Interface)
Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Katherine Shapiro, Wenbin Guo, Kody Armann, Natalie Pace, Bing Shen, Jicheng Wang, Jonathan Beckel, William Groat, Changfeng Tai Tags: Basic Research Source Type: research