Pudendal Nerve Block by Low ‐Frequency (≤1 kHz) Biphasic Electrical Stimulation

ConclusionThis study discovered that LFBS ( ≤1 kHz), like high-frequency (≥5 kHz) biphasic stimulation (HFBS), can induce poststimulation block. The result provides support for the theory that biphasic stimulation waveforms block axonal conduction by changing intracellular and extracellular ion concentrations. The post-LFBS block provid es the opportunity to develop new neuromodulation devices for clinical applications where initial nerve firing is acceptable.

Source: Neuromodulation: Technology at the Neural Interface - August 28, 2021 Category: Biotechnology Authors: Katherine Shapiro, Wenbin Guo, Kody Armann, Natalie Pace, Bing Shen, Jicheng Wang, Jonathan Beckel, William Groat, Changfeng Tai Tags: Basic Research Source Type: research