The effect of exercise on blood concentrations of angiogenesis markers in older adults: A systematic review and meta-analysis
Neurobiol Aging. 2023 Dec 19;135:15-25. doi: 10.1016/j.neurobiolaging.2023.12.004. Online ahead of print.ABSTRACTImpaired angiogenesis is associated with cognitive decline in older adults. While exercise has been broadly associated with increased angiogenesis, the relevant mechanisms in older adults are not clear. Here, we present a systematic review and meta-analysis on the relationship between exercise and specific blood angiogenesis markers in older adults to better understand the relevant mechanisms. MEDLINE, Embase, and Cochrane CENTRAL were searched for original reports of angiogenesis markers' concentrations in bloo...
Source: Neurobiology of Aging - December 26, 2023 Category: Geriatrics Authors: Bing Xin Song Laiba Azhar Grace Ka Yi Koo Susan Marzolini Damien Gallagher Walter Swardfager Clara Chen Joycelyn Ba Nathan Herrmann Krista L Lanct ôt Source Type: research

The effect of exercise on blood concentrations of angiogenesis markers in older adults: A systematic review and meta-analysis
Neurobiol Aging. 2023 Dec 19;135:15-25. doi: 10.1016/j.neurobiolaging.2023.12.004. Online ahead of print.ABSTRACTImpaired angiogenesis is associated with cognitive decline in older adults. While exercise has been broadly associated with increased angiogenesis, the relevant mechanisms in older adults are not clear. Here, we present a systematic review and meta-analysis on the relationship between exercise and specific blood angiogenesis markers in older adults to better understand the relevant mechanisms. MEDLINE, Embase, and Cochrane CENTRAL were searched for original reports of angiogenesis markers' concentrations in bloo...
Source: Neurobiology of Aging - December 26, 2023 Category: Geriatrics Authors: Bing Xin Song Laiba Azhar Grace Ka Yi Koo Susan Marzolini Damien Gallagher Walter Swardfager Clara Chen Joycelyn Ba Nathan Herrmann Krista L Lanct ôt Source Type: research

The effect of exercise on blood concentrations of angiogenesis markers in older adults: A systematic review and meta-analysis
Neurobiol Aging. 2023 Dec 19;135:15-25. doi: 10.1016/j.neurobiolaging.2023.12.004. Online ahead of print.ABSTRACTImpaired angiogenesis is associated with cognitive decline in older adults. While exercise has been broadly associated with increased angiogenesis, the relevant mechanisms in older adults are not clear. Here, we present a systematic review and meta-analysis on the relationship between exercise and specific blood angiogenesis markers in older adults to better understand the relevant mechanisms. MEDLINE, Embase, and Cochrane CENTRAL were searched for original reports of angiogenesis markers' concentrations in bloo...
Source: Neurobiology of Aging - December 26, 2023 Category: Geriatrics Authors: Bing Xin Song Laiba Azhar Grace Ka Yi Koo Susan Marzolini Damien Gallagher Walter Swardfager Clara Chen Joycelyn Ba Nathan Herrmann Krista L Lanct ôt Source Type: research

Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease
Neurobiol Aging. 2023 Nov 28;135:1-14. doi: 10.1016/j.neurobiolaging.2023.11.010. Online ahead of print.ABSTRACTHere, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with Parkinson's disease dementia (PDD) than in patients with Alzheimer's disease dementia (ADD). A Eurasian database provided clinical-demographic-rsEEG datasets in 73 PDD patients, 35 ADD patients, and 25 matched cognitively unimpaired (Healthy) persons. The eLORETA freeware was used to estimate cortical rsEEG sour...
Source: Neurobiology of Aging - December 24, 2023 Category: Geriatrics Authors: Claudio Babiloni Giuseppe Noce Federico Tucci Dharmendra Jakhar Raffaele Ferri Simonetta Panerai Valentina Catania Andrea Soricelli Marco Salvatore Flavio Nobili Dario Arnaldi Francesco Fam à Carla Buttinelli Franco Giubilei Marco Onofrj Fabrizio Stocchi Source Type: research

Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease
Neurobiol Aging. 2023 Nov 28;135:1-14. doi: 10.1016/j.neurobiolaging.2023.11.010. Online ahead of print.ABSTRACTHere, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with Parkinson's disease dementia (PDD) than in patients with Alzheimer's disease dementia (ADD). A Eurasian database provided clinical-demographic-rsEEG datasets in 73 PDD patients, 35 ADD patients, and 25 matched cognitively unimpaired (Healthy) persons. The eLORETA freeware was used to estimate cortical rsEEG sour...
Source: Neurobiology of Aging - December 24, 2023 Category: Geriatrics Authors: Claudio Babiloni Giuseppe Noce Federico Tucci Dharmendra Jakhar Raffaele Ferri Simonetta Panerai Valentina Catania Andrea Soricelli Marco Salvatore Flavio Nobili Dario Arnaldi Francesco Fam à Carla Buttinelli Franco Giubilei Marco Onofrj Fabrizio Stocchi Source Type: research

Poor reactivity of posterior electroencephalographic alpha rhythms during the eyes open condition in patients with dementia due to Parkinson's disease
Neurobiol Aging. 2023 Nov 28;135:1-14. doi: 10.1016/j.neurobiolaging.2023.11.010. Online ahead of print.ABSTRACTHere, we hypothesized that the reactivity of posterior resting-state electroencephalographic (rsEEG) alpha rhythms during the transition from eyes-closed to -open condition might be lower in patients with Parkinson's disease dementia (PDD) than in patients with Alzheimer's disease dementia (ADD). A Eurasian database provided clinical-demographic-rsEEG datasets in 73 PDD patients, 35 ADD patients, and 25 matched cognitively unimpaired (Healthy) persons. The eLORETA freeware was used to estimate cortical rsEEG sour...
Source: Neurobiology of Aging - December 24, 2023 Category: Geriatrics Authors: Claudio Babiloni Giuseppe Noce Federico Tucci Dharmendra Jakhar Raffaele Ferri Simonetta Panerai Valentina Catania Andrea Soricelli Marco Salvatore Flavio Nobili Dario Arnaldi Francesco Fam à Carla Buttinelli Franco Giubilei Marco Onofrj Fabrizio Stocchi Source Type: research

Reliability and generalizability of neural speech tracking in younger and older adults
Neurobiol Aging. 2023 Nov 21;134:165-180. doi: 10.1016/j.neurobiolaging.2023.11.007. Online ahead of print.ABSTRACTNeural tracking of spoken speech is considered a potential clinical biomarker for speech-processing difficulties, but the reliability of neural speech tracking is unclear. Here, younger and older adults listened to stories in two sessions while electroencephalography was recorded to investigate the reliability and generalizability of neural speech tracking. Speech tracking amplitude was larger for older than younger adults, consistent with an age-related loss of inhibition. The reliability of neural speech tra...
Source: Neurobiology of Aging - December 16, 2023 Category: Geriatrics Authors: Ryan A Panela Francesca Copelli Bj örn Herrmann Source Type: research

Reliability and generalizability of neural speech tracking in younger and older adults
Neurobiol Aging. 2023 Nov 21;134:165-180. doi: 10.1016/j.neurobiolaging.2023.11.007. Online ahead of print.ABSTRACTNeural tracking of spoken speech is considered a potential clinical biomarker for speech-processing difficulties, but the reliability of neural speech tracking is unclear. Here, younger and older adults listened to stories in two sessions while electroencephalography was recorded to investigate the reliability and generalizability of neural speech tracking. Speech tracking amplitude was larger for older than younger adults, consistent with an age-related loss of inhibition. The reliability of neural speech tra...
Source: Neurobiology of Aging - December 16, 2023 Category: Geriatrics Authors: Ryan A Panela Francesca Copelli Bj örn Herrmann Source Type: research

Reliability and generalizability of neural speech tracking in younger and older adults
Neurobiol Aging. 2023 Nov 21;134:165-180. doi: 10.1016/j.neurobiolaging.2023.11.007. Online ahead of print.ABSTRACTNeural tracking of spoken speech is considered a potential clinical biomarker for speech-processing difficulties, but the reliability of neural speech tracking is unclear. Here, younger and older adults listened to stories in two sessions while electroencephalography was recorded to investigate the reliability and generalizability of neural speech tracking. Speech tracking amplitude was larger for older than younger adults, consistent with an age-related loss of inhibition. The reliability of neural speech tra...
Source: Neurobiology of Aging - December 16, 2023 Category: Geriatrics Authors: Ryan A Panela Francesca Copelli Bj örn Herrmann Source Type: research

Reliability and generalizability of neural speech tracking in younger and older adults
Neurobiol Aging. 2023 Nov 21;134:165-180. doi: 10.1016/j.neurobiolaging.2023.11.007. Online ahead of print.ABSTRACTNeural tracking of spoken speech is considered a potential clinical biomarker for speech-processing difficulties, but the reliability of neural speech tracking is unclear. Here, younger and older adults listened to stories in two sessions while electroencephalography was recorded to investigate the reliability and generalizability of neural speech tracking. Speech tracking amplitude was larger for older than younger adults, consistent with an age-related loss of inhibition. The reliability of neural speech tra...
Source: Neurobiology of Aging - December 16, 2023 Category: Geriatrics Authors: Ryan A Panela Francesca Copelli Bj örn Herrmann Source Type: research

Reliability and generalizability of neural speech tracking in younger and older adults
Neurobiol Aging. 2023 Nov 21;134:165-180. doi: 10.1016/j.neurobiolaging.2023.11.007. Online ahead of print.ABSTRACTNeural tracking of spoken speech is considered a potential clinical biomarker for speech-processing difficulties, but the reliability of neural speech tracking is unclear. Here, younger and older adults listened to stories in two sessions while electroencephalography was recorded to investigate the reliability and generalizability of neural speech tracking. Speech tracking amplitude was larger for older than younger adults, consistent with an age-related loss of inhibition. The reliability of neural speech tra...
Source: Neurobiology of Aging - December 16, 2023 Category: Geriatrics Authors: Ryan A Panela Francesca Copelli Bj örn Herrmann Source Type: research

Reliability and generalizability of neural speech tracking in younger and older adults
Neurobiol Aging. 2023 Nov 21;134:165-180. doi: 10.1016/j.neurobiolaging.2023.11.007. Online ahead of print.ABSTRACTNeural tracking of spoken speech is considered a potential clinical biomarker for speech-processing difficulties, but the reliability of neural speech tracking is unclear. Here, younger and older adults listened to stories in two sessions while electroencephalography was recorded to investigate the reliability and generalizability of neural speech tracking. Speech tracking amplitude was larger for older than younger adults, consistent with an age-related loss of inhibition. The reliability of neural speech tra...
Source: Neurobiology of Aging - December 16, 2023 Category: Geriatrics Authors: Ryan A Panela Francesca Copelli Bj örn Herrmann Source Type: research

Age-related differences in fMRI subsequent memory effects are directly linked to local grey matter volume differences
Neurobiol Aging. 2023 Dec 5;134:160-164. doi: 10.1016/j.neurobiolaging.2023.12.002. Online ahead of print.ABSTRACTEpisodic memory performance declines with increasing age, and older adults typically show reduced activation of inferior temporo-parietal cortices in functional magnetic resonance imaging (fMRI) studies of episodic memory formation. Given the age-related cortical volume loss, it is conceivable that age-related reduction of memory-related fMRI activity may be partially attributable to reduced grey matter volume (GMV). We performed a voxel-wise multimodal neuroimaging analysis of fMRI correlates of successful mem...
Source: Neurobiology of Aging - December 14, 2023 Category: Geriatrics Authors: Jasmin M Kizilirmak Joram Soch Anni Richter Bj örn H Schott Source Type: research

Age-related differences in fMRI subsequent memory effects are directly linked to local grey matter volume differences
Neurobiol Aging. 2023 Dec 5;134:160-164. doi: 10.1016/j.neurobiolaging.2023.12.002. Online ahead of print.ABSTRACTEpisodic memory performance declines with increasing age, and older adults typically show reduced activation of inferior temporo-parietal cortices in functional magnetic resonance imaging (fMRI) studies of episodic memory formation. Given the age-related cortical volume loss, it is conceivable that age-related reduction of memory-related fMRI activity may be partially attributable to reduced grey matter volume (GMV). We performed a voxel-wise multimodal neuroimaging analysis of fMRI correlates of successful mem...
Source: Neurobiology of Aging - December 14, 2023 Category: Geriatrics Authors: Jasmin M Kizilirmak Joram Soch Anni Richter Bj örn H Schott Source Type: research

Neurite-based white matter alterations in MAPT mutation carriers: A multi-shell diffusion MRI study in the ALLFTD consortium
Neurobiol Aging. 2023 Dec 10;134:135-145. doi: 10.1016/j.neurobiolaging.2023.12.001. Online ahead of print.ABSTRACTWe assessed white matter (WM) integrity in MAPT mutation carriers (16 asymptomatic, 5 symptomatic) compared to 31 non-carrier family controls using diffusion tensor imaging (DTI) (fractional anisotropy; FA, mean diffusivity; MD) and neurite orientation dispersion and density imaging (NODDI) (neurite density index; NDI, orientation and dispersion index; ODI). Linear mixed-effects models accounting for age and family relatedness revealed alterations across DTI and NODDI metrics in all mutation carriers and in sy...
Source: Neurobiology of Aging - December 13, 2023 Category: Geriatrics Authors: Nick Corriveau-Lecavalier Nirubol Tosakulwong Timothy G Lesnick Angela J Fought Robert I Reid Christopher G Schwarz Matthew L Senjem Clifford R Jack David T Jones Prashanthi Vemuri Rosa Rademakers Eliana Marisa Ramos Daniel H Geschwind David S Knopman Hug Source Type: research