Length of light exposure alters energy metabolism in mice
Nature Reviews Endocrinology, Published online: 13 September 2023; doi:10.1038/s41574-023-00904-6Length of light exposure alters energy metabolism in mice (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 13, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Obesity-induced and weight-loss-induced physiological factors affecting weight regain
Nature Reviews Endocrinology, Published online: 11 September 2023; doi:10.1038/s41574-023-00887-4Regaining weight after successful weight loss is a common problem for people with obesity. This Review discusses the potential physiological mechanisms underlying weight regain after weight loss and possible strategies to counter weight regain. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 11, 2023 Category: Endocrinology Authors: Marleen A. van Baak Edwin C. M. Mariman Source Type: research
Non-invasive daily profiles of tissue adrenal steroids
Nature Reviews Endocrinology, Published online: 11 September 2023; doi:10.1038/s41574-023-00901-9In a new study, an ambulatory microdialysis system combined with ultrasensitive liquid chromatography-tandem mass spectrometry enabled the building of a 24-h high-resolution profile of adrenal steroids in the tissue by sampling interstitial fluid in 214 healthy volunteers. Daily and ultradian variations of eight free steroids, including cortisol and aldosterone, have been demonstrated, which opens new diagnostic perspectives for endocrine diseases. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 11, 2023 Category: Endocrinology Authors: Fid éline Bonnet-Serrano J érôme Bertherat Source Type: research
Inflammation-induced adrenal dysfunction
Nature Reviews Endocrinology, Published online: 11 September 2023; doi:10.1038/s41574-023-00896-3Acute inflammation triggers activation of the hypothalamic–pituitary–adrenal axis, but whether it could also impede the adrenocortical response to adrenocorticotropic hormone remains controversial. A new study using preclinical models of acute inflammation demonstrates dysregulation of energy metabolism in adrenocortical cells, resulting in oxidative stress that induces disruption of steroidogenesis. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 11, 2023 Category: Endocrinology Authors: Vasileios Chortis David T. Breault Source Type: research
Control of adipose tissue cellularity by the terminal complement cascade
Nature Reviews Endocrinology, Published online: 11 September 2023; doi:10.1038/s41574-023-00900-wAdipocytes have high levels of many components of the complement system. These components are involved in antimicrobial activities, but also have the potential to regulate the maintenance and turn-over of adipocytes under normal and pathophysiological conditions through positive and negative regulation of the membrane attack complex. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 11, 2023 Category: Endocrinology Authors: Ilja L. Kruglikov Philipp E. Scherer Source Type: research
Microbial metabolism linked to insulin resistance
Nature Reviews Endocrinology, Published online: 11 September 2023; doi:10.1038/s41574-023-00903-7Microbial metabolism linked to insulin resistance (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 11, 2023 Category: Endocrinology Authors: Shimona Starling Source Type: research
Long-term effects of untreated leptin deficiency
Nature Reviews Endocrinology, Published online: 11 September 2023; doi:10.1038/s41574-023-00902-8Long-term effects of untreated leptin deficiency (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 11, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
The influence of the circulatory system on tissue ageing: does the fountain of youth lie in our blood?
Nature Reviews Endocrinology, Published online: 08 September 2023; doi:10.1038/s41574-023-00895-4The influence of the circulatory system on tissue ageing: does the fountain of youth lie in our blood? (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 8, 2023 Category: Endocrinology Authors: Alexander Keeble Source Type: research
Advanced neurobiological tools to interrogate metabolism
Nature Reviews Endocrinology, Published online: 06 September 2023; doi:10.1038/s41574-023-00885-6This Review discusses the key principles and uses of engineered neurobiological tools, such as optogenetics and chemogenetics. The authors discuss examples of their use in the metabolism field and highlight important points to consider when choosing an experimental technique. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 6, 2023 Category: Endocrinology Authors: Paul Nicholas Mirabella Henning Fenselau Source Type: research
Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement
Nature Reviews Endocrinology, Published online: 05 September 2023; doi:10.1038/s41574-023-00886-5This Consensus Statement, which is endorsed by the Pituitary Society, offers evidence-based graded consensus recommendations and key summary points for clinical practice on the diagnosis and management of prolactinomas. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 5, 2023 Category: Endocrinology Authors: Stephan Petersenn Maria Fleseriu Felipe F. Casanueva Andrea Giustina Nienke Biermasz Beverly M. K. Biller Marcello Bronstein Philippe Chanson Hidenori Fukuoka Monica Gadelha Yona Greenman Mark Gurnell Ken K. Y. Ho J ürgen Honegger Adriana G. Ioachimescu Source Type: research
Bile acid species shows potential for NAFLD
Nature Reviews Endocrinology, Published online: 04 September 2023; doi:10.1038/s41574-023-00897-2Bile acid species shows potential for NAFLD (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 4, 2023 Category: Endocrinology Authors: Shimona Starling Source Type: research
NK3R antagonists: a novel approach for menopause symptoms
Nature Reviews Endocrinology, Published online: 01 September 2023; doi:10.1038/s41574-023-00891-8Most women experience vasomotor symptoms during menopause, which considerably affect their quality of life. While vasomotor symptoms can be substantially reduced with menopausal hormone therapy, many women are unable or choose not to take hormone therapy. Now, studies have demonstrated that neurokinin 3 receptor antagonists have a level of effectiveness against vasomotor symptoms that is similar to that of hormone therapy. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 1, 2023 Category: Endocrinology Authors: Simone Elder Nanette Santoro Source Type: research
Microglial inflammatory signalling improves glucose tolerance
Nature Reviews Endocrinology, Published online: 21 August 2023; doi:10.1038/s41574-023-00892-7Microglial inflammatory signalling improves glucose tolerance (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 21, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Pituitary adenoma or neuroendocrine tumour: the need for an integrated prognostic classification
Nature Reviews Endocrinology, Published online: 17 August 2023; doi:10.1038/s41574-023-00883-8This Perspective presents the outcomes of an interdisciplinary international workshop that addressed the implications of the WHO classification change of pituitary adenoma to neuroendocrine tumours. The authors propose that a comprehensive classification system be developed integrating clinical, genetic, biochemical, radiological, pathological and molecular information for all anterior pituitary neoplasms. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 17, 2023 Category: Endocrinology Authors: Ken K. Y. Ho Ursula B. Kaiser Phillippe Chanson Monica Gadelha John Wass Lynnette Nieman Andrew Little Manish K. Aghi Lori Raetzman Kalmon Post Gerald Raverot Alexander D. Borowsky Dana Erickson Justo P. Casta ño Edward R. Laws Maria Chiara Zatelli Jill Source Type: research
β-adrenergic receptors feel the heat against obesity
Nature Reviews Endocrinology, Published online: 17 August 2023; doi:10.1038/s41574-023-00889-2β-adrenergic receptors feel the heat against obesity (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 17, 2023 Category: Endocrinology Authors: Srinithi Ranganathan Emma L. Robinson Source Type: research
