Genomic alterations in thyroid cancer: biological and clinical insights
Nature Reviews Endocrinology, Published online: 04 December 2023; doi:10.1038/s41574-023-00920-6Genomic data from patients with thyroid cancer, combined with information on mutation-specific mechanisms from experimental models, is transforming the thyroid cancer research field. This Review summarizes the genetic alterations involved in follicular cell-derived thyroid cancer initiation and progression and their biological and clinical implications. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 4, 2023 Category: Endocrinology Authors: I ñigo Landa Maria E. Cabanillas Source Type: research
Metabolic control of puberty: 60 years in the footsteps of Kennedy and Mitra’s seminal work
Nature Reviews Endocrinology, Published online: 04 December 2023; doi:10.1038/s41574-023-00919-zKey papers on the role of nutrition and metabolic cues in puberty timing were published in 1963, and there have been many advances in this field in the subsequent 60 years. This Review discusses the latest advances in basic and translational sciences underlying the nutritional and metabolic control of pubertal development. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 4, 2023 Category: Endocrinology Authors: Greg M. Anderson Jennifer W. Hill Ursula B. Kaiser Victor M. Navarro Ken K. Ong John R. B. Perry Vincent Prevot Manuel Tena-Sempere Carol F. Elias Source Type: research
GIP regulates body weight via GABAergic neurons
Nature Reviews Endocrinology, Published online: 29 November 2023; doi:10.1038/s41574-023-00930-4GIP regulates body weight via GABAergic neurons (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 29, 2023 Category: Endocrinology Authors: Shimona Starling Source Type: research
β-cells protected from T1DM by early senescence programme
Nature Reviews Endocrinology, Published online: 24 November 2023; doi:10.1038/s41574-023-00928-yβ-cells protected from T1DM by early senescence programme (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 24, 2023 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
SGLT inhibitors: a serendipitous glycaemic tale
Nature Reviews Endocrinology, Published online: 20 November 2023; doi:10.1038/s41574-023-00923-3SGLT inhibitors: a serendipitous glycaemic tale (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 20, 2023 Category: Endocrinology Authors: Shubham Agarwal Ildiko Lingvay Source Type: research
The metabolic mythos of ketones
Nature Reviews Endocrinology, Published online: 20 November 2023; doi:10.1038/s41574-023-00925-1The metabolic mythos of ketones (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 20, 2023 Category: Endocrinology Authors: Jonathan Low Kaja Falkenhain Source Type: research
How a common NAFLD genetic risk variant affects human metabolism
Nature Reviews Endocrinology, Published online: 14 November 2023; doi:10.1038/s41574-023-00924-2How a common NAFLD genetic risk variant affects human metabolism (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 14, 2023 Category: Endocrinology Authors: Shimona Starling Source Type: research
The ageing thyroid: implications for longevity and patient care
Nature Reviews Endocrinology, Published online: 03 November 2023; doi:10.1038/s41574-023-00911-7Thyroid hormones have key functions throughout the body. However, thyroid function declines with age and thyroid diseases increase in prevalence. This Review outlines our current knowledge about how thyroid function changes with age and the implications for patient care. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - November 3, 2023 Category: Endocrinology Authors: Diana van Heemst Source Type: research
Health equity in endocrinology
Nature Reviews Endocrinology, Published online: 26 October 2023; doi:10.1038/s41574-023-00912-6Health equity is when every person can achieve their full potential for health and wellbeing. In this Viewpoint, global experts discuss the root causes and contributing factors to health inequity in endocrinology. Potential action points and research directions to help reduce health disparities are also discussed. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 26, 2023 Category: Endocrinology Authors: Kathryn Backholer Osagie Ebekozien Karen Hofman J. Jaime Miranda Samuel Seidu Source Type: research
Antivirals in the treatment of new-onset T1DM
Nature Reviews Endocrinology, Published online: 26 October 2023; doi:10.1038/s41574-023-00918-0Antivirals in the treatment of new-onset T1DM (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 26, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Macrophage and T cell networks in adipose tissue
Discussion of these cells is used as an example of how metabolic tissue niches can dictate immune cell function in unique ways that diverge from the classic understanding of leukocyte biology. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 23, 2023 Category: Endocrinology Authors: Ramiah D. Jacks Carey N. Lumeng Source Type: research
A new endometrial organoid: synthetically engineered matrix enhances epithelial–stromal interactions
Nature Reviews Endocrinology, Published online: 23 October 2023; doi:10.1038/s41574-023-00917-1Over the past decade, the focus on modelling the human endometrium and its cyclical transformations has intensified, driven in part by the lack of notable progress in treating endometrial diseases. Gnecco and collaborators now unveil a cutting-edge endometrial organoid culture using synthetic hydrogels with endometrial niche peptides and epithelial and stromal cells. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 23, 2023 Category: Endocrinology Authors: J. Julie Kim Source Type: research
Author Correction: Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement
Nature Reviews Endocrinology, Published online: 17 October 2023; doi:10.1038/s41574-023-00916-2Author Correction: Diagnosis and management of prolactin-secreting pituitary adenomas: a Pituitary Society international Consensus Statement (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 17, 2023 Category: Endocrinology Authors: Stephan Petersenn Maria Fleseriu Felipe F. Casanueva Andrea Giustina Nienke Biermasz Beverly M. K. Biller Marcello Bronstein Philippe Chanson Hidenori Fukuoka Monica Gadelha Yona Greenman Mark Gurnell Ken K. Y. Ho J ürgen Honegger Adriana G. Ioachimescu Source Type: research
Inter-organ crosstalk during development and progression of type 2 diabetes mellitus
Nature Reviews Endocrinology, Published online: 16 October 2023; doi:10.1038/s41574-023-00898-1Inter-organ crosstalk is increasingly understood as an important mechanism contributing to insulin resistance and β-cell failure, the key features of type 2 diabetes mellitus. This Review discusses mediators of inter-organ crosstalk in type 2 diabetes mellitus, its pathogenesis and its related complications. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 16, 2023 Category: Endocrinology Authors: Georgia Xourafa Melis Korbmacher Michael Roden Source Type: research
Metabolic elasticity — a new trait associated with health?
Nature Reviews Endocrinology, Published online: 13 October 2023; doi:10.1038/s41574-023-00914-4A recent study by Zhou and colleagues proposed that low metabolic elasticity and gene elasticity are involved in the metabolic alterations observed in ageing and obesity. Here, we discuss some of their findings to provide a viewpoint on these potential new traits associated with metabolic health. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 13, 2023 Category: Endocrinology Authors: Rodrigo Fern ández-Verdejo Jose E. Galgani Source Type: research
