New role for bone marrow adipocytes in obesity
Nature Reviews Endocrinology, Published online: 17 October 2022; doi:10.1038/s41574-022-00767-3New role for bone marrow adipocytes in obesity (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 17, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Author Correction: Skeletal and extraskeletal disorders of biomineralization
Nature Reviews Endocrinology, Published online: 17 October 2022; doi:10.1038/s41574-022-00768-2Author Correction: Skeletal and extraskeletal disorders of biomineralization (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 17, 2022 Category: Endocrinology Authors: Michael T. Collins Gemma Marcucci Hans-Joachim Anders Giovanni Beltrami Jane A. Cauley Peter R. Ebeling Rajiv Kumar Agn ès Linglart Luca Sangiorgi Dwight A. Towler Ria Weston Michael. P. Whyte Maria Luisa Brandi Bart Clarke Rajesh V. Thakker Source Type: research
Defective UPR linked to β-cell dedifferentiation
Nature Reviews Endocrinology, Published online: 13 October 2022; doi:10.1038/s41574-022-00766-4Defective UPR linked to β-cell dedifferentiation (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 13, 2022 Category: Endocrinology Authors: Katrin Legg Source Type: research
Delving into insulin receptor regulation
Nature Reviews Endocrinology, Published online: 13 October 2022; doi:10.1038/s41574-022-00765-5Delving into insulin receptor regulation (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 13, 2022 Category: Endocrinology Authors: Shimona Starling Source Type: research
The multiple roles of life stress in metabolic disorders
Nature Reviews Endocrinology, Published online: 12 October 2022; doi:10.1038/s41574-022-00746-8Life stress is known to affect the development and progression of metabolic diseases. This Review discusses the pathophysiological mechanisms underlying the association between stress and metabolic disease, and evaluates the epidemiological evidence for the influence of stress on metabolic disease. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 12, 2022 Category: Endocrinology Authors: Mika Kivim äki Alessandro Bartolomucci Ichiro Kawachi Source Type: research
The ATP-binding cassette proteins ABCB1 and ABCC1 as modulators of glucocorticoid action
Nature Reviews Endocrinology, Published online: 11 October 2022; doi:10.1038/s41574-022-00745-9This Review discusses the ATP-binding cassette (ABC) proteins ABCB1 and ABCC1 and their preferential cellular export of cortisol and corticosterone, respectively. The article also explores the potential to select therapeutic glucocorticoids on the basis of their different tendencies for export to avoid harmful adverse effects. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 11, 2022 Category: Endocrinology Authors: Kerri Devine Elisa Villalobos Catriona J. Kyle Ruth Andrew Rebecca M. Reynolds Roland H. Stimson Mark Nixon Brian R. Walker Source Type: research
Endosomal trafficking in metabolic homeostasis and diseases
Nature Reviews Endocrinology, Published online: 10 October 2022; doi:10.1038/s41574-022-00737-9Membrane trafficking is essential for the sorting and distribution of several different types of cargo between different intracellular compartments and the plasma membrane. In this Review, advances in understanding the contribution of the endosomal system to metabolic physiology and pathology are outlined. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 10, 2022 Category: Endocrinology Authors: Jerome Gilleron Anja Zeigerer Source Type: research
Obesity phenotypes: explaining the unexplained
Nature Reviews Endocrinology, Published online: 07 October 2022; doi:10.1038/s41574-022-00760-wObesity phenotypes: explaining the unexplained (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 7, 2022 Category: Endocrinology Authors: Shimona Starling Source Type: research
Hormonal regulation of mammary gland development and lactation
Nature Reviews Endocrinology, Published online: 03 October 2022; doi:10.1038/s41574-022-00742-yThe mammary gland is responsible for lactation and is regulated by the coordinated actions of reproductive and metabolic hormones. This Review discusses the hormonal regulation of lactation, hormonal functions of the mammary gland, the hormone composition of human milk, and endocrine and metabolic diseases that cause lactation insufficiency. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - October 3, 2022 Category: Endocrinology Authors: Fadil M. Hannan Taha Elajnaf Laura N. Vandenberg Stephen H. Kennedy Rajesh V. Thakker Source Type: research
Diet composition affects mitochondria trafficking in adipose tissue
Nature Reviews Endocrinology, Published online: 28 September 2022; doi:10.1038/s41574-022-00755-7Diet composition affects mitochondria trafficking in adipose tissue (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 28, 2022 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Control loop designs in health and disease
Nature Reviews Endocrinology, Published online: 27 September 2022; doi:10.1038/s41574-022-00753-9Control loop designs are widely present in biology but can undergo errors, which can be fixed using generic strategies. Loop designs in response to organismal stress exhibit distinct features and are under ongoing investigations. Understanding control theory as an organizing principle in biology creates a broader perspective on endocrine and non-endocrine systems. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 27, 2022 Category: Endocrinology Authors: Nikolai P. Jaschke Source Type: research
HOTAIR underlies the region-specific development of adipose tissue
Nature Reviews Endocrinology, Published online: 21 September 2022; doi:10.1038/s41574-022-00754-8The long non-coding RNA HOTAIR is exclusively expressed in gluteofemoral subcutaneous adipose tissue (GSAT) and is functionally required for GSAT adipocyte differentiation. A genetic variation analysis showed that the minor allele of rs1443512 is associated with reduced HOTAIR expression and decreased adipose tissue mass in the leg and gynoid regions. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 21, 2022 Category: Endocrinology Authors: Dan Xu Lei Sun Source Type: research
A global view of hypertensive disorders and diabetes mellitus during pregnancy
Nature Reviews Endocrinology, Published online: 15 September 2022; doi:10.1038/s41574-022-00734-yTwo maternal cardiometabolic disorders, hypertensive disorders in pregnancy (HDP) and gestational diabetes mellitus (GDM), affect many pregnant individuals worldwide. This Review discusses the global disease burden and risk factors for HDP and GDM and discusses public health interventions that might help reduce the associated mortality and morbidity. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 15, 2022 Category: Endocrinology Authors: Li Jiang Kun Tang Laura A. Magee Peter von Dadelszen Alec Ekeroma Xuan Li Enyao Zhang Zulfiqar A. Bhutta Source Type: research
MKRN3 involved in puberty timing
Nature Reviews Endocrinology, Published online: 12 September 2022; doi:10.1038/s41574-022-00748-6MKRN3 involved in puberty timing (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 12, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
GLP1-mediated delivery of tesaglitazar improves glucose metabolism in mice
Nature Reviews Endocrinology, Published online: 09 September 2022; doi:10.1038/s41574-022-00750-yGLP1-mediated delivery of tesaglitazar improves glucose metabolism in mice (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 9, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
