A perspective on treating type 1 diabetes mellitus before insulin is needed
Nature Reviews Endocrinology, Published online: 13 March 2023; doi:10.1038/s41574-023-00816-5This Perspective discusses potential approaches to managing patients in the early stages of developing type 1 diabetes mellitus, which could enable the initiation of insulin therapy to be delayed in some patients. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 13, 2023 Category: Endocrinology Authors: Danijela Tatovic Parth Narendran Colin M. Dayan Source Type: research
Interventions in people newly diagnosed with type 1 diabetes mellitus
Nature Reviews Endocrinology, Published online: 10 March 2023; doi:10.1038/s41574-023-00825-4Interventions in people newly diagnosed with type 1 diabetes mellitus (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 10, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Large study on hormone therapy for transgender youth provides reassurance amid treatment politicization
Nature Reviews Endocrinology, Published online: 10 March 2023; doi:10.1038/s41574-023-00824-5Findings from the largest longitudinal study (315 participants) on psychosocial functioning in transgender or nonbinary youth after 2 years of gender-affirming hormone (GAH) therapy were recently published in New England Journal of Medicine. At a time of heightened politicization of this treatment, this study adds to the growing literature that demonstrates benefits of GAH therapy for transgender youth. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 10, 2023 Category: Endocrinology Authors: Ximena Lopez Laura E. Kuper Source Type: research
The metabolic benefits of exercise-induced hepatic autophagy
Nature Reviews Endocrinology, Published online: 07 March 2023; doi:10.1038/s41574-023-00823-6The metabolic benefits of exercise-induced hepatic autophagy (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 7, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
On the cutting edge: perspectives in bioenergetics
Nature Reviews Endocrinology, Published online: 03 March 2023; doi:10.1038/s41574-023-00820-9The field of bioenergetics is rapidly expanding with new discoveries of mechanisms and potential therapeutic targets. The 2023 Keystone symposium on ‘Bioenergetics in Health and Disease’, which was jointly held with the symposium ‘Adipose Tissue: Energizing Good Fat’, consisted of a powerhouse line-up of researchers who shared their insights. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 3, 2023 Category: Endocrinology Authors: Melia Granath-Panelo Anna Krook Jared Rutter Shingo Kajimura Source Type: research
GLP1: the early steps of a success story
Nature Reviews Endocrinology, Published online: 02 March 2023; doi:10.1038/s41574-023-00821-8GLP1: the early steps of a success story (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 2, 2023 Category: Endocrinology Authors: Rula Bany Bakar Source Type: research
A novel resource to study endometriosis at the single-cell level
Nature Reviews Endocrinology, Published online: 02 March 2023; doi:10.1038/s41574-023-00814-7A transcriptomic analysis of endometriosis and comparison tissues has been conducted, revealing a rich and complex catalogue of single-cell-based expression data. This resource is an invaluable building block towards single cell profiling at scale, aiding research into endometriosis pathogenesis and new ways of diagnosing and treating the disease. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - March 2, 2023 Category: Endocrinology Authors: Luz Garc ía-Alonso Krina T. Zondervan Roser Vento-Tormo Source Type: research
Reprogramming lymph nodes in type 1 diabetes mellitus
Nature Reviews Endocrinology, Published online: 24 February 2023; doi:10.1038/s41574-023-00819-2Reprogramming lymph nodes in type 1 diabetes mellitus (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 24, 2023 Category: Endocrinology Authors: Shimona Starling Source Type: research
Sulfonylurea secondary failure mechanism identified
Nature Reviews Endocrinology, Published online: 22 February 2023; doi:10.1038/s41574-023-00815-6Sulfonylurea secondary failure mechanism identified (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 22, 2023 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Consensus Statement on the definition and classification of metabolic hyperferritinaemia
Nature Reviews Endocrinology, Published online: 17 February 2023; doi:10.1038/s41574-023-00807-6This Consensus Statement discusses the relationship between hyperferritinaemia and iron accumulation in individuals with metabolic dysfunction. The authors propose an updated definition and a provisional staging system for metabolic hyperferritinaemia, highlight research gaps and provide suggestions for the design and outcome measures for future studies. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 17, 2023 Category: Endocrinology Authors: Luca Valenti Elena Corradini Leon A. Adams Elmar Aigner Saleh Alqahtani Marco Arrese Edouard Bardou-Jacquet Elisabetta Bugianesi Jose-Manuel Fernandez-Real Domenico Girelli Hannes Hagstr öm Benjamin Henninger Kris Kowdley Guido Ligabue Donald McClain Fab Source Type: research
EDC exposure in 3D genome memory in transgenerational obesity
Nature Reviews Endocrinology, Published online: 15 February 2023; doi:10.1038/s41574-023-00810-xA new study reveals that exposure of pregnant mice to an endocrine disrupting chemical, bisphenol A, induces multi-transgenerational (up to six) inheritance of obesity in their descendants. This effect depends on CTCF-dependent chromatin reorganization in the sperm, a synergistic outcome of altered DNA methylation, RNA modification and long-range chromatin interactions. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 15, 2023 Category: Endocrinology Authors: Xudong Zhang Qi Chen Source Type: research
Aster pathway maintains hepatic cholesterol homeostasis
Nature Reviews Endocrinology, Published online: 15 February 2023; doi:10.1038/s41574-023-00812-9Aster pathway maintains hepatic cholesterol homeostasis (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 15, 2023 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Serine slows diabetic neuropathy in mice
Nature Reviews Endocrinology, Published online: 13 February 2023; doi:10.1038/s41574-023-00811-wSerine slows diabetic neuropathy in mice (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 13, 2023 Category: Endocrinology Authors: Shimona Starling Source Type: research
The effect of long-term statin use on diabetic nephropathy
Nature Reviews Endocrinology, Published online: 10 February 2023; doi:10.1038/s41574-023-00813-8The effect of long-term statin use on diabetic nephropathy (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 10, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
A role for circulating levels of uridine in regulating hunger and food intake
Nature Reviews Endocrinology, Published online: 02 February 2023; doi:10.1038/s41574-023-00808-5A role for circulating levels of uridine in regulating hunger and food intake (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - February 2, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
