T-bet+ B cells promote metabolic disease
Nature Reviews Endocrinology, Published online: 15 August 2022; doi:10.1038/s41574-022-00736-wT-bet+ B cells promote metabolic disease (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 15, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Primary bilateral macronodular adrenal hyperplasia: definitely a genetic disease
Nature Reviews Endocrinology, Published online: 03 August 2022; doi:10.1038/s41574-022-00718-yPrimary bilateral macronodular adrenocortical hyperplasia (PBMAH) is an adrenal cause of Cushing syndrome. This Review outlines recent progress in understanding the genetics of PBMAH. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 3, 2022 Category: Endocrinology Authors: Isadora P. Cavalcante Annabel Berthon Maria C. Fragoso Martin Reincke Constantine A. Stratakis Bruno Ragazzon J érôme Bertherat Source Type: research
Lactation duration affects obesity risk in rat offspring
Nature Reviews Endocrinology, Published online: 03 August 2022; doi:10.1038/s41574-022-00732-0Lactation duration affects obesity risk in rat offspring (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 3, 2022 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Optimising stem cells for diabetes mellitus therapy
Nature Reviews Endocrinology, Published online: 03 August 2022; doi:10.1038/s41574-022-00731-1Optimising stem cells for diabetes mellitus therapy (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 3, 2022 Category: Endocrinology Authors: Shimona Starling Source Type: research
Lactate as a major myokine and exerkine
Nature Reviews Endocrinology, Published online: 01 August 2022; doi:10.1038/s41574-022-00724-0Lactate as a major myokine and exerkine (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 1, 2022 Category: Endocrinology Authors: George A. Brooks Adam D. Osmond Jose A. Arevalo Casey C. Curl Justin J. Duong Michael A. Horning Diana D. Moreno Santillan Robert G. Leija Source Type: research
Reply to ‘Lactate as a major myokine and exerkine’
Nature Reviews Endocrinology, Published online: 01 August 2022; doi:10.1038/s41574-022-00726-yReply to ‘Lactate as a major myokine and exerkine’ (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 1, 2022 Category: Endocrinology Authors: Lisa S. Chow Robert E. Gerszten Joan M. Taylor Bente K. Pedersen Henriette van Praag Scott Trappe Mark A. Febbraio Zorina S. Galis Yunling Gao Jacob M. Haus Ian R. Lanza Carl J. Lavie Chih-Hao Lee Alejandro Lucia Cedric Moro Ambarish Pandey Jeremy M. Robb Source Type: research
Fetoplacental oxygen homeostasis in pregnancies with maternal diabetes mellitus and obesity
Nature Reviews Endocrinology, Published online: 28 July 2022; doi:10.1038/s41574-022-00717-zDiabetes mellitus or obesity during pregnancy can cause fetal hypoxia, resulting in reduced fetal growth. This Review discusses the metabolic causes of fetal hypoxia in pregnancies with diabetes mellitus and/or obesity and the fetal adaptations to this oxygen deficit. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 28, 2022 Category: Endocrinology Authors: Gernot Desoye Anthony M. Carter Source Type: research
The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits
Nature Reviews Endocrinology, Published online: 28 July 2022; doi:10.1038/s41574-022-00716-0Rare monogenic obesity is caused by pathogenic variants in single genes, while common obesity mostly has a polygenic basis. This Review discusses genetic obesity traits, the emergence of novel pharmacological treatment options that target the central melanocortin pathway and future innovative therapies. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 28, 2022 Category: Endocrinology Authors: Anke Hinney Antje K örner Pamela Fischer-Posovszky Source Type: research
Insulin sensitive human adipocytes for in vitro studies
Nature Reviews Endocrinology, Published online: 27 July 2022; doi:10.1038/s41574-022-00727-xAdipocyte insulin resistance is a driving force for systemic insulin resistance. Advances in human stem cell culture have established conditions for human adipocytes that give rise to a reproducible population of adipocytes that retain a high level of insulin sensitivity, paving the way for high throughput screening approaches. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 27, 2022 Category: Endocrinology Authors: Leon G. Straub Philipp E. Scherer Source Type: research
Exposing skin to ultraviolet irradiation increases food intake in male individuals
Nature Reviews Endocrinology, Published online: 26 July 2022; doi:10.1038/s41574-022-00729-9Exposing skin to ultraviolet irradiation increases food intake in male individuals (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 26, 2022 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Highlights from ADA 82nd Scientific Sessions
Nature Reviews Endocrinology, Published online: 26 July 2022; doi:10.1038/s41574-022-00728-wHighlights from ADA 82nd Scientific Sessions (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 26, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Metabolic mechanisms for and treatment of NAFLD or NASH occurring after liver transplantation
Nature Reviews Endocrinology, Published online: 15 July 2022; doi:10.1038/s41574-022-00711-5This Review outlines the occurrence of non-alcoholic fatty liver disease and non-alcoholic steatohepatitis (NASH) in patients who have undergone liver transplantation for prior NASH-related cirrhosis (recurrent) or other liver indications (de novo). (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 15, 2022 Category: Endocrinology Authors: Amedeo Lonardo Alessandro Mantovani Salvatore Petta Amedeo Carraro Christopher D. Byrne Giovanni Targher Source Type: research
Lipolysis of bone marrow adipocytes fuels bone
Nature Reviews Endocrinology, Published online: 12 July 2022; doi:10.1038/s41574-022-00723-1Lipolysis of bone marrow adipocytes fuels bone (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 12, 2022 Category: Endocrinology Authors: Shimona Starling Source Type: research
GLP1 receptor agonist overcomes SGLT2 inhibitor-related overeating
Nature Reviews Endocrinology, Published online: 11 July 2022; doi:10.1038/s41574-022-00722-2Sodium–glucose cotransporter 2 (SGLT2) inhibitor treatment affects central regulation of appetite and satiety, which results in increased carbohydrate intake. It has now been demonstrated that these effects might be blunted by combining SGLT2 inhibitors with glucagon-like peptide 1 receptor agonists to further facilitate weight loss in patients with type 2 diabetes mellitus. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 11, 2022 Category: Endocrinology Authors: Matthias Bl üher Source Type: research
The interplay between diabetes mellitus and menopause: clinical implications
Nature Reviews Endocrinology, Published online: 07 July 2022; doi:10.1038/s41574-022-00708-0Menopause can increase the risk of diabetes mellitus, while existing diabetes mellitus can cause early menopause. This Review discusses the interaction of diabetes mellitus and the menopause, including therapeutic management strategies for both conditions. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - July 7, 2022 Category: Endocrinology Authors: Irene Lambrinoudaki Stavroula A. Paschou Eleni Armeni Dimitrios G. Goulis Source Type: research
