A transporter on the move
Nature Reviews Endocrinology, Published online: 05 January 2024; doi:10.1038/s41574-023-00944-yA transporter on the move (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 5, 2024 Category: Endocrinology Authors: Steffen H. Raun Source Type: research
Scrutinizing the effect of BPS on adipose tissue
Nature Reviews Endocrinology, Published online: 05 January 2024; doi:10.1038/s41574-023-00945-xScrutinizing the effect of BPS on adipose tissue (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 5, 2024 Category: Endocrinology Authors: Shimona Starling Source Type: research
Oxytocin regulates adipose tissue lipolysis
Nature Reviews Endocrinology, Published online: 05 January 2024; doi:10.1038/s41574-023-00947-9Oxytocin regulates adipose tissue lipolysis (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - January 5, 2024 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Emerging mechanisms of obesity-associated immune dysfunction
Nature Reviews Endocrinology, Published online: 21 December 2023; doi:10.1038/s41574-023-00932-2In this Review, the emerging cellular and molecular mechanisms by which obesity impairs key aspects of immunity are discussed, including changes in the abundance of key hormones, dysregulation of adipose-tissue-derived extracellular vesicles and dysregulation of polyunsaturated fatty acid metabolism. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 21, 2023 Category: Endocrinology Authors: Saame Raza Shaikh Melinda A. Beck Yazan Alwarawrah Nancie J. MacIver Source Type: research
The intersection between ghrelin, metabolism and circadian rhythms
Nature Reviews Endocrinology, Published online: 20 December 2023; doi:10.1038/s41574-023-00927-zThis Review describes a promising, bidirectional role for ghrelin in the interaction between circadian rhythms and metabolism. The authors explore how ghrelin affects outputs of circadian rhythm — including neuronal activity, circulating growth hormone levels, locomotor activity and eating behaviour — and discuss how circadian rhythms influence ghrelin expression. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 20, 2023 Category: Endocrinology Authors: Soumya S. Kulkarni Omprakash Singh Jeffrey M. Zigman Source Type: research
Luteal phase support in assisted reproductive technology
Nature Reviews Endocrinology, Published online: 18 December 2023; doi:10.1038/s41574-023-00921-5This Review describes the luteal phase of natural menstrual cycles and in vitro fertilization (IVF) cycles. The authors highlight the need for luteal phase support during IVF, outlining various luteal phase support regimens, mechanisms for luteal phase deficiency and potential biomarkers of endometrial receptivity. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 18, 2023 Category: Endocrinology Authors: Akanksha Garg Agata P. Zielinska Arthur C. Yeung Rebecca Abdelmalak Runzhi Chen Aleena Hossain Alisha Israni Scott M. Nelson Andy V. Babwah Waljit S. Dhillo Ali Abbara Source Type: research
Pituitary stem cells: past, present and future perspectives
Nature Reviews Endocrinology, Published online: 15 December 2023; doi:10.1038/s41574-023-00922-4This Review discusses notable discoveries in pituitary stem cell function and highlights important areas for current and future research, including the use of pituitary organoids for the advancement of pituitary stem cell biology and pituitary organogenesis as well as potential therapeutic approaches. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 15, 2023 Category: Endocrinology Authors: Mar ía Inés Pérez Millán Leonard Y. M. Cheung Florencia Mercogliano Maria Andrea Camilletti Gonzalo T. Chirino Felker Lucia N. Moro Santiago Miriuka Michelle L. Brinkmeier Sally A. Camper Source Type: research
Deciphering the role of leptin in weight gain associated with anti-psychotic medications
Nature Reviews Endocrinology, Published online: 15 December 2023; doi:10.1038/s41574-023-00941-1Deciphering the role of leptin in weight gain associated with anti-psychotic medications (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 15, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Management of phaeochromocytoma and paraganglioma in patients with germline SDHB pathogenic variants: an international expert Consensus statement
Nature Reviews Endocrinology, Published online: 14 December 2023; doi:10.1038/s41574-023-00926-0The management of patients with pheochromocytoma and paraganglioma associated with pathogenic variants in SDHB can be challenging. This Consensus statement aims to provide a guide for the clinical decision-making process in these patients. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 14, 2023 Category: Endocrinology Authors: David Ta ïeb Svenja N ölting Nancy D. Perrier Martin Fassnacht Jorge A. Carrasquillo Ashley B. Grossman Roderick Clifton-Bligh George B. Wanna Zachary G. Schwam Laurence Amar Isabelle Bourdeau Ruth T. Casey Joakim Crona Cheri L. Deal Jaydira Del Rivero Source Type: research
A pivotal year for NAFLD and NASH therapeutics
Nature Reviews Endocrinology, Published online: 14 December 2023; doi:10.1038/s41574-023-00939-9The metabolic dysfunction that characterizes obesity and type 2 diabetes mellitus affects not only the heart and kidneys, but also the liver. Although lifestyle modification remains the cornerstone in the management of metabolic liver diseases, the field has progressed this year, with a new definition, validation of non-invasive biomarkers and numerous clinical trials. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 14, 2023 Category: Endocrinology Authors: Jean-Fran çois Dufour Source Type: research
Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia
Nature Reviews Endocrinology, Published online: 14 December 2023; doi:10.1038/s41574-023-00940-2Author Correction: Consensus Statement on the definition and classification of metabolic hyperferritinaemia (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 14, 2023 Category: Endocrinology Authors: Luca Valenti Elena Corradini Leon A. Adams Elmar Aigner Saleh Alqahtani Marco Arrese Edouard Bardou-Jacquet Elisabetta Bugianesi Jose-Manuel Fernandez-Real Domenico Girelli Hannes Hagstr öm Benjamin Henninger Kris Kowdley Guido Ligabue Donald McClain Fab Source Type: research
Advances in incretin-based therapeutics for obesity
Nature Reviews Endocrinology, Published online: 07 December 2023; doi:10.1038/s41574-023-00938-wThe year 2023 brought reports of highly effective glucagon-like peptide 1 (GLP1) mono-agonists or combinations with amylin receptor agonists. Results for monomolecular co-agonists that added glucagon receptor and/or glucose-dependent insulinotropic polypeptide (GIP) receptor agonism to GLP1 receptor activation were also published in 2023. Interestingly, antagonistic GIP receptor antibodies conjugated with a GLP1 agonist were also shown to be effective. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 7, 2023 Category: Endocrinology Authors: Mette M. Rosenkilde Source Type: research
Harnessing the inflammatory processes in endometriosis
Nature Reviews Endocrinology, Published online: 07 December 2023; doi:10.1038/s41574-023-00937-xThe pathophysiology of endometriosis is underpinned by a complex interplay of inflammatory processes that are responsible for the local and systemic effects of the condition. Recent studies delve further into this inflammatory interplay; using animal models, they identify potential therapeutic tools and remind us to look beyond the endometriotic lesions. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 7, 2023 Category: Endocrinology Authors: Jane E. Girling Source Type: research
Highlights from SfE BES 2023
Nature Reviews Endocrinology, Published online: 07 December 2023; doi:10.1038/s41574-023-00935-zHighlights from SfE BES 2023 (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 7, 2023 Category: Endocrinology Authors: Claire Greenhill Source Type: research
Type 1 diabetes mellitus: a brave new world
Nature Reviews Endocrinology, Published online: 06 December 2023; doi:10.1038/s41574-023-00936-yOne hundred years after the Nobel prize was bestowed on Banting and McLeod for the ‘discovery’ of insulin, we are again seeing major evolutions in the management of type 1 diabetes mellitus, with the prospect of achieving disease control beyond mere management now becoming real. Here, we discuss the latest, most notable developments. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - December 6, 2023 Category: Endocrinology Authors: Pieter-Jan Martens Chantal Mathieu Source Type: research
