MKRN3 involved in puberty timing
Nature Reviews Endocrinology, Published online: 12 September 2022; doi:10.1038/s41574-022-00748-6MKRN3 involved in puberty timing (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 12, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
GLP1-mediated delivery of tesaglitazar improves glucose metabolism in mice
Nature Reviews Endocrinology, Published online: 09 September 2022; doi:10.1038/s41574-022-00750-yGLP1-mediated delivery of tesaglitazar improves glucose metabolism in mice (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 9, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Cognitive function in T1DM improved by hybrid closed-loop insulin delivery
Nature Reviews Endocrinology, Published online: 09 September 2022; doi:10.1038/s41574-022-00752-wCognitive function in T1DM improved by hybrid closed-loop insulin delivery (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 9, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Patients’ insights into diabetes insipidus
Nature Reviews Endocrinology, Published online: 09 September 2022; doi:10.1038/s41574-022-00751-xPatients’ insights into diabetes insipidus (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 9, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
New mechanism of Cushing disease revealed
Nature Reviews Endocrinology, Published online: 09 September 2022; doi:10.1038/s41574-022-00749-5New mechanism of Cushing disease revealed (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 9, 2022 Category: Endocrinology Authors: Shimona Starling Source Type: research
Modelling metabolic diseases and drug response using stem cells and organoids
Nature Reviews Endocrinology, Published online: 07 September 2022; doi:10.1038/s41574-022-00733-zOrganoids are a promising tool for modelling diseases in vitro. This Review discusses the progress in developing liver and adipose tissue organoids to study metabolic diseases such as obesity and non-alcoholic fatty liver disease and assesses the strengths and limitations of these systems. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 7, 2022 Category: Endocrinology Authors: Wenxiang Hu Mitchell A. Lazar Source Type: research
AcroBATics: how dying brown adipocytes trigger browning
Nature Reviews Endocrinology, Published online: 05 September 2022; doi:10.1038/s41574-022-00743-xThermogenic brown and beige adipocytes have gained much attention as potential therapeutic targets in obesity and related cardiometabolic disease. A recent paper in Nature identifies inosine, released from apoptotic brown adipocytes, as an inducer of thermogenic adipose tissue, thereby uncovering an unexpected and novel mechanism of adipose tissue plasticity. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 5, 2022 Category: Endocrinology Authors: Julia Zinngrebe Pamela Fischer-Posovszky Source Type: research
Strategies for modelling endometrial diseases
Nature Reviews Endocrinology, Published online: 01 September 2022; doi:10.1038/s41574-022-00725-zEndometrial diseases affect many women yet often have unclear pathogenesis and no definitive treatment. This Review assesses the current systems for modelling endometrial diseases in vitro and outlines future directions for these model systems. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - September 1, 2022 Category: Endocrinology Authors: Alina R. Murphy Hannes Campo J. Julie Kim Source Type: research
Primary aldosteronism — a multidimensional syndrome
Nature Reviews Endocrinology, Published online: 31 August 2022; doi:10.1038/s41574-022-00730-2This Review discusses how redefining the primary aldosteronism syndrome as a multidimensional spectrum will affect the approach to the diagnosis and subtyping of primary aldosteronism. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 31, 2022 Category: Endocrinology Authors: Adina F. Turcu Jun Yang Anand Vaidya Source Type: research
Cold-induced BAT stunts tumour growth
Nature Reviews Endocrinology, Published online: 25 August 2022; doi:10.1038/s41574-022-00738-8Cold-induced BAT stunts tumour growth (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 25, 2022 Category: Endocrinology Authors: Shimona Starling Source Type: research
Vitamin D supplementation and fracture risk
Nature Reviews Endocrinology, Published online: 25 August 2022; doi:10.1038/s41574-022-00741-zVitamin D supplementation and fracture risk (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 25, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Endoscopic sleeve gastroplasty: safe and effective
Nature Reviews Endocrinology, Published online: 25 August 2022; doi:10.1038/s41574-022-00739-7Endoscopic sleeve gastroplasty: safe and effective (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 25, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
Genetic risk scores improve prediction of obesity in survivors of childhood cancer
Nature Reviews Endocrinology, Published online: 25 August 2022; doi:10.1038/s41574-022-00740-0Genetic risk scores improve prediction of obesity in survivors of childhood cancer (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 25, 2022 Category: Endocrinology Authors: Olivia Tysoe Source Type: research
The role of iron in host–microbiota crosstalk and its effects on systemic glucose metabolism
Nature Reviews Endocrinology, Published online: 19 August 2022; doi:10.1038/s41574-022-00721-3Patients with obesity-associated metabolic dysfunction exhibit dysregulation in iron homeostasis and alterations in gut microbiota composition and functionality. This Review discusses the bidirectional relationships between the host and the microbiota in the acquisition of elemental iron and the implications for glucose metabolism. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 19, 2022 Category: Endocrinology Authors: Jordi Mayneris-Perxachs Jos é María Moreno-Navarrete Jos é Manuel Fernández-Real Source Type: research
Glucagon receptor antagonists might stimulate β-cell expansion
Nature Reviews Endocrinology, Published online: 15 August 2022; doi:10.1038/s41574-022-00735-xIn a recent issue of Cell Reports, Xi et al. reported on their studies of an anti-glucagon receptor antibody in several mouse models of insulin-deficient diabetes mellitus, in which they show substantial increase in β-cell mass from enhanced replication and transdifferentiation of glucagon-expressing α-cells to insulin-expressing β-cells. (Source: Nature Reviews Endocrinology)
Source: Nature Reviews Endocrinology - August 15, 2022 Category: Endocrinology Authors: Maria F. Rubin de Celis Susan Bonner-Weir Source Type: research
