The promise of new anti-obesity therapies arising from knowledge of genetic obesity traits

Nature Reviews Endocrinology, Published online: 28 July 2022; doi:10.1038/s41574-022-00716-0Rare monogenic obesity is caused by pathogenic variants in single genes, while common obesity mostly has a polygenic basis. This Review discusses genetic obesity traits, the emergence of novel pharmacological treatment options that target the central melanocortin pathway and future innovative therapies.
Source: Nature Reviews Endocrinology - Category: Endocrinology Authors: Source Type: research