Membership of the ESM
J Vasc Res 2017;54:258 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - August 25, 2017 Category: Research Source Type: research
Conference Calendar
J Vasc Res 2017;54:257 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - August 25, 2017 Category: Research Source Type: research
Fetal Sheep Mesenteric Resistance Arteries: Functional and Structural Maturation
Conclusion: Vascular maturation during late ovine gestation involves an increase in resting wall tension and the vasoconstrictor and vasodilator capacity of the mesenteric resistance arteries. Absence of structural changes in the tunica media and the lack of an increase in vasoregulator receptor/enzyme expression suggest that vasoactive responses are due to the maturation of intracellular pathways at this gestational age.J Vasc Res 2017;54:259-271 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - August 15, 2017 Category: Research Source Type: research
MicroRNA-Dependent Control of Serotonin-Induced Pulmonary Arterial Contraction
Conclusion: Our findings show that 5-HT receptor signaling in the arterial wall is subject to regulation by microRNAs and that this entails altered 5-HT2A receptor expression and signaling.J Vasc Res 2017;54:246-256 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - August 10, 2017 Category: Research Source Type: research
β-Sarcoglycan Deficiency Reduces Atherosclerotic Plaque Development in ApoE-Null Mice
Conclusions: Our results indicate that the dystrophin-glycoprotein complex and β-sarcoglycan can affect the atherosclerotic process. Furthermore, the results show the effects of β-sarcoglycan deficiency on adipose tissue and lipid metabolism, which may also have contributed to the atherosclerotic plaque reduction.J Vasc Res 2017;54:235-245 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - July 28, 2017 Category: Research Source Type: research
Advanced Glycation End-Products Downregulate HoxA9EC through Activation of Nuclear Factor Kappa B by Reciprocal Interaction
In conclusion, AGEs could induce endothelial dysfunction through NF-#x03BA;B-dependent HoxA9EC downregulation by reciprocal interaction, and the enhancement of HoxA9EC expression could attenuate the impairment.J Vasc Res 2017;54:226-234 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - July 19, 2017 Category: Research Source Type: research
Photoacoustic Imaging: A Novel Tool for Detecting Carotid Artery Thrombosis in Mice
In this study, we employed a novel imaging method, photoacoustic imaging (PAI), to study thrombosis in a mouse model of ferric chloride (FeCl3)-induced arterial thrombosis and compared the ability of this method to detect thrombosis with that of a conventional imaging method, namely, ultrasound. The mice (n = 20) were divided equally into the following 4 groups: (1) a normal group, and (2) 3 experimental groups, in which the left common carotid artery was treated with 20% FeCl3 for 1, 3, or 5 min, respectively. After 24 h, PAI detected thrombi of different sizes and generated images, enabling us to assess the changes in st...
Source: Journal of Vascular Research - July 7, 2017 Category: Research Source Type: research
Oral Nitrate Increases Microvascular Reactivity and the Number of Visible Perfused Microvessels in Healthy Volunteers
Nitric oxide (NO) plays an important role in controlling microcirculatory function, but the effects of exogenous administration of nitrate (NO3-) on the microcirculation have not been well studied. We evaluated whether NO3- could influence the microvascular response to hypoxia in 17 healthy volunteers. We used a vascular occlusion test (VOT) to assess the response of near-infrared spectroscopy-derived indexes to hypoxic stress before and 2 h 15 min after oral administration of 800 mg potassium nitrate. We also monitored changes in the sublingual microcirculation using side-stream dark-field (SDF) video microscopy. The desc...
Source: Journal of Vascular Research - July 6, 2017 Category: Research Source Type: research
Lysophosphatidylcholine Acyltransferase-3 Expression Is Associated with Atherosclerosis Progression
In this study, we analyzed human and mouse atherosclerotic tissues to gain insight into the arachidonyl-PC metabolism involving LPCAT3 using imaging mass spectrometry. The data revealed a complementary distribution of arachidonyl-PC and LPC in human atherosclerotic tissues with arachidonyl-PC decreasing and LPC increasing as atherosclerosis progressed. Furthermore, we found a homologous distribution of LPCAT3 expression and arachidonyl-PC based on atherosclerotic progression. In contrast, in ApoE-deficient mice, atherosclerosis increased both arachidonyl-PC accumulation and LPCAT3 expression. Taken together, these findings...
Source: Journal of Vascular Research - July 5, 2017 Category: Research Source Type: research
Measurement of Aortic Cell Fluid-Phase Pinocytosis in vivo by Flow Cytometry
Conclusion: This new technique allows for the measurement of fluid-phase pinocytosis by aortic cells in vivo, making it possible to examine the cell-signaling molecules and drugs that affect this process. Published by S. Karger AG, BaselJ Vasc Res 2017;54:195-199 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - June 15, 2017 Category: Research Source Type: research
Membership of the ESM
J Vasc Res 2017;54:194 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - May 30, 2017 Category: Research Source Type: research
Conference Calendar
J Vasc Res 2017;54:193 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - May 30, 2017 Category: Research Source Type: research
Title Page
J Vasc Res 2017;54(suppl 1):I-II (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - May 23, 2017 Category: Research Source Type: research
ESM-EVBO 2017. 2nd Joint Meeting of the European Society for Microcirculation (ESM) and European VascularBiology Organisation (EVBO). Geneva, Switzerland, 29 May to 1 June 2017: Abstracts
J Vasc Res 2017;54(suppl 1):1-80 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - May 23, 2017 Category: Research Source Type: research
Backup Mechanisms Maintain PACAP/VIP-Induced Arterial Relaxations in Pituitary Adenylate Cyclase-Activating Polypeptide-Deficient Mice
Conclusion: Our data suggest that in PACAP deficiency, backup mechanisms maintain arterial relaxations to polypeptides, indicating an important physiological role for the PACAP pathway in the regulation of vascular tone.J Vasc Res 2017;54:180-192 (Source: Journal of Vascular Research)
Source: Journal of Vascular Research - May 10, 2017 Category: Research Source Type: research
