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Correlation of skeletal muscle depletion with acute toxicities for cervical cancer patients undergoing concurrent chemoradiation: A prospective study
Conclusion: Patients with cancer cachexia are at higher risk for radiation enteritis during chemoradiation for cervical cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Sampuran Acharya Kumar Manur Janaki Gururajachar Vinay Prabhu Martin Source Type: research

Cisplatin versus gemcitabine as concurrent chemoradiotherapy in squamous cell carcinoma cervix: A comparative study of clinical response and toxicities
Conclusion: Cisplatin has a better treatment response as compared to gemcitabine as concomitant chemotherapy agent with external beam radiation therapy. Hematological toxicity was more in gemcitabine arm and gastrointestinal toxicity was more in cisplatin arm. The skin toxicities were comparable in both the arms. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Ramandeep Singh Raja Paramjeet Singh Banipal Lajya Devi Goyal Source Type: research

The tolerance to chemoradiation for cervical cancer patients: A comparative prospective study of rural versus urban population
Conclusions: Tolerance to chemoradiation, disease-free survival, and overall survival are similar in both urban and rural patients of cervical cancer, with more enteritis in urban group. However, this did not increase OTT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Mohan Kumar Somashekar Janaki Manur Gururajachar TR Arul Ponni Kirthi Agrahara Koushik Ram Charith Alva Source Type: research

Dosimetric analysis of intensity-modulated radiation therapy and volumetric-modulated arc therapy in comparison with conventional box technique in the treatment of carcinoma cervix: An impact of prosthetic implant
Conclusion: VMAT has an edge over other techniques in terms of target coverage and sparing of critical organs in the presence of metallic prosthesis. Information about the geometry and density of prosthesis will be beneficial for treatment planning. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Manindra Bhushan Deepak Tripathi Girigesh Yadav Lalit Kumar Rahul Lal Chowdhary Anjali K Pahuja Mahamood Suhail Swarupa Mitra Munish Gairola Source Type: research

Relationship of irradiated bone marrow volume and neutropenia in patients undergoing concurrent chemoradiation therapy for cervical cancer
Conclusions: High-dose irradiation to the larger volume of BM prevents compensatory hyperplasia which leads to neutropenia in patients undergoing CCRT for cervical cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Febin Antony Jomon Raphael Chalissery K Mathew Varghese G Paul Gopu Minu Boban Source Type: research

A randomized study for dosimetric assessment and clinical impact of bone marrow sparing intensity-modulated radiation therapy versus 3-dimensional conformal radiation therapy on hematological and gastrointestinal toxicities in cervical cancer
Conclusions: IMRT significantly reduces acute hematologic and GI toxicities compared with 3DCRT with a better dosimetry profile. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Ankita Rungta Kapoor Rajendra L Bhalavat Manish Chandra Vibhay Pareek Zaiba Moosa Saurabh Markana P Nandakumar Pratibha Bauskar NV Shincy Source Type: research

The immunohistochemical biomarker B-cell lymphoma-2 expression in malignant and premalignant lesions of the uterine cervix and its association with human papillomavirus infection
Conclusion: Bcl-2 IHC seems to have variable expression among CIN cases. Although its expression is low among invasive cancer cases when compared with preinvasive lesions, the difference is not significant. Similarly, no significant association was found between Bcl-2 expression and HPV infections. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Prasanta Kumar Nayak Nighat Hussain Sanjay Negi Sarita Agrawal Nilaj Bagde Subarna Mitra Vandita Singh Source Type: research

A histopathological and immunohistochemistry analysis of endometrial lesions among women presenting with abnormal uterine bleeding
Conclusion: It can be concluded that the combination of the proliferative and apoptotic markers and the ratio will help as a tool in aiding the diagnosis of endometrial lesions for patients presenting with AUB. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Nazia M Walvir Safia Rana Zeeba S Jairajpuri Sujata Jetley Aruna Nigam Source Type: research

Audit of radiation oncology practice: Lessons from a new private hospital in Delhi, India
Conclusions: Compared to the previously published audit from an academic RO department in Delhi, this audit from a private hospital has shown (i) lesser waiting time, (ii) improved treatment compliance, (iii) utilization of higher techniques, and (iv) a lower duration of RT course. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Bidhu K Mohanti Anusheel Munshi Ganesh Tharmar Biplab Sarkar Source Type: research

Long term outcome and late toxicity Of SIB-IMRT in definitive management of head and neck cancers in patients not suitable for chemo-radiotherapy
Conclusions: Efficacy and late toxicity of IMRT-SIB observed in our study suggest it as a suitable treatment option for patients who are not fit for chemoradiation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Narayan Pratap Singh Rohini Khurana Shantanu Sapru Madhup Rastogi Ajeet Kumar Gandhi Satyajeet Rath Rahat Hadi Surendra Prasad Mishra Anoop Kumar Srivastava Avinav Bharti Kamal Sahni Mohammad Ali Ramakant Tiwari Source Type: research

Association of MTHFR 677C & #62;T polymorphism with breast cancer risk: A case & #8211;control study and meta-analysis
Conclusions: MTHFR 677C>T polymorphism is not a risk factor for breast cancer in Punjabi population. Inconsistency with the meta-analysis can be due to ethnic diversity. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Harmesh Lal Bhavna Sharma Vasudha Sambyal Kamlesh Guleria Neeti Rajan Singh Manjit Singh Uppal Mridu Manjari Meena Sudan Source Type: research

Erratum: Adjuvant therapy fails to show survival benefit for patients with spindle cell carcinoma: Evidence from the surveillance, epidemiology, and end results database
Journal of Cancer Research and Therapeutics 2022 18(5):1450-1450 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 27, 2022 Category: Cancer & Oncology Source Type: research

Erratum: Efficacy and safety of transcatheter arterial chemoembolization plus hepatic arterial infusion chemotherapy in the treatment of advanced hepatocellular carcinoma with portal vein tumor thrombosis in the main trunk
Journal of Cancer Research and Therapeutics 2022 18(5):1449-1449 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 27, 2022 Category: Cancer & Oncology Source Type: research

Chinese primary adrenal lymphoma complicated with adrenal crisis: A case report and literature review
This report describes the case of a 67-year-old man with fatigue, poor appetite, and weight loss. Positron emission tomography and computed tomography (PET-CT) scan showed irregular mass-like soft tissue density shadows were noted in the bilateral adrenal glands and immunohistochemical (IHC) studies confirmed the diagnosis of PAL with multiple metastases throughout the body. This report characterizes the clinical manifestations in patients with PAL. When the disease progresses to bilateral adrenal involvement, it may be accompanied by adrenal insufficiency or even adrenal crisis occurred. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 27, 2022 Category: Cancer & Oncology Authors: Yan Zhang Li Zheng Yi Ai Min Luo Lixin Shi Qiao Zhang Source Type: research

Hypophysitis: A rare but noteworthy immune-related adverse event secondary to camrelizumab therapy
Xiaoying Han, Min Meng, Tiehong Zhang, Jiao Wang, Guanghui Huang, Yang Ni, Wenhong Li, Jianjian Dai, Xia Yang, Xin YeJournal of Cancer Research and Therapeutics 2022 18(5):1440-1443 The programmed cell death 1 (PD-1) inhibitor – camrelizumab – is a promising agent for the treatment of several malignancies. Secondary hypophysitis has been reported in patients treated with the other PD-1 inhibitors such as nivolumab and pembrolizumab. However, camrelizumab-related hypophysitis has not yet been described. Herein, we report three cases of hypophysitis secondary to camrelizumab therapy. Case 1 was a 6...
Source: Journal of Cancer Research and Therapeutics - September 27, 2022 Category: Cancer & Oncology Authors: Xiaoying Han Min Meng Tiehong Zhang Jiao Wang Guanghui Huang Yang Ni Wenhong Li Jianjian Dai Xia Yang Xin Ye Source Type: research