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Synchronous benign Brenner & #39;s tumor of the ovary with leiomyoma and endometrial adenocarcinoma in a postmenopausal female
Jude Ogechukwu OkoyeJournal of Cancer Research and Therapeutics 2022 18(4):1208-1209 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Jude Ogechukwu Okoye Source Type: research

A rare localization of a common disease: Primary uterine Non-Hodgkin lymphoma mimicking leiomyosarcoma
We present an 80-year-old female patient diagnosed with diffuse large B-cell lymphoma (DLBCL) with a single focus of the uterus. The patient's only complaint was abnormal uterine bleeding. Magnetic resonance imaging revealed an intramural-subserous-submucous multiple mass lesion with minimal contrast enhancement mimicking leiomyosarcoma. Diffuse pathological 18F-fluorodeoxyglucose uptake was detected in the entire uterus corpus and cervix on positron emission tomography/computed tomography (PET/CT) scanning. The pathology of the endocervical and endometrial curettage material obtained was DLBCL; the patient was ...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Sibel Goksel Elanur Karaman Pinar Karacin & #350;afak Ers & #246;z Source Type: research

Anal cancer with isolated ischial fossa lymph node metastases: A rare entity in the oligometastatic dilemma
Issa Mohamad, Ramiz Abuhijlih, Mousa Alkaldi, Akram Al-Ibraheem, Sami Khatib, Fawzi AbuhijlaJournal of Cancer Research and Therapeutics 2022 18(4):1202-1204 Carcinoma of the anal canal is relatively rare cancer with a low propensity for metastasis. A literature review identifies two cases with ischial fossa metastases from anal cancer. The authors present the case of a 62-year-old male with moderately differentiated squamous cell carcinoma of the anal canal who presented with isolated ischial fossa lymph node (LN) confirmed by fluoro-2-deoxy-D-glucose positron emission tomography/computed tomography and pelvic magnetic re...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Issa Mohamad Ramiz Abuhijlih Mousa Alkaldi Akram Al-Ibraheem Sami Khatib Fawzi Abuhijla Source Type: research

Quadruple metachronous primary cancer in a single patient: A rare case report
Tauseef Ali, Aafreen Khan, Vivek Kathed, Shalu Verma, Anil Sarolkar, Virendra BhandariJournal of Cancer Research and Therapeutics 2022 18(4):1199-1201 Multiple primary cancer is a condition where multiple occurrences of different malignancies occur in the same individual. As there is a rise in the long-term survival of patients, multiple primary cancer is now not a rare entity. To see four different tumors in the same patient is very rare, and here, we report the case of a 60-year-old female patient with quadruple primary cancer of bilateral breast, esophagus, and sarcoma of the leg. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Tauseef Ali Aafreen Khan Vivek Kathed Shalu Verma Anil Sarolkar Virendra Bhandari Source Type: research

Carcinoma of the pyriform sinus with mediastinal metastasis successfully treated with chemoradiotherapy in resource-constraint setup
Pallavi Kalbande, Pournima Kale, Aarathi ArdhaJournal of Cancer Research and Therapeutics 2022 18(4):1195-1198 Squamous cell carcinoma (SCC) of the pyriform sinus with metastatic mediastinal mass is staged as IVC and routinely treated with palliative intent. Here, we report a case cured with radical chemoradiotherapy without CT simulator, lead cutouts, and advanced techniques such as three-dimensional conformal radiation therapy, intensity-modulated radiation therapy, image-guided radiotherapy, and volumetric modulated arc therapy or stereotactic body radiotherapy. A 67-year-old male presented with SCC of the right pyrifo...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Pallavi Kalbande Pournima Kale Aarathi Ardha Source Type: research

Mucinous carcinoma of the gallbladder- two rare case reports
We present two cases of mucinous carcinoma of the gallbladder one of which was incidentally detected. The first case is a 65-year-old female who was diagnosed clinically with a suspected case of carcinoma of the gallbladder with the help of contrast-enhanced computed tomography. Microscopy showed extensive areas of mucin pools (>90% of the tumor), atypical cells in three-dimensional clusters, and scattered singly in the mucin pools. Immunohistochemistry revealed a strong expression of MUC2 by the tumor cells. The second case is a 60-year-old female who was diagnosed clinically with a case of chronic c...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Mitakshara Sharma Ashutosh Rath Reena Tomar Nita Khurana Deepak Ghuliani Source Type: research

Diffuse-type giant cell tumor: Pigmented villonodular synovitis of patellar fat pad
In this study, we presented a case of diffuse PVNS originating from the patellar fat pad. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Erdem Degirmenci Abdullah Alper Sahin Yunus Emre Bulum Mehmet Gamsizkan Zafer Orhan Source Type: research

Primary leiomyosarcoma kidney & #8211; A rare entity with a diagnostic challenge
Dimple Chaudhary, Ashutosh Rath, Shramana Mandal, Nita Khurana, PN AgarwalJournal of Cancer Research and Therapeutics 2022 18(4):1186-1188 Primary leiomyosarcoma kidney is a rare tumor with an aggressive nature. Leiomyosarcoma is one of the common histologic types of the sarcomas, comprising 60% of all sarcomas. Sarcomatoid renal cell carcinoma is a close differential of renal leiomyosarcoma as both tumors have spindle-shaped cells. The former has a more pleomorphic character with nuclear grade four, which can be differentiated on the basis of immunohistochemistry. Hence, the diagnosis of primary renal leiomyos...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Dimple Chaudhary Ashutosh Rath Shramana Mandal Nita Khurana PN Agarwal Source Type: research

Trastuzumab and thyroid dysfunction: An association to be aware of
We report two cases of HER2-positive early BC patients who developed hypothyroidism during maintenance therapy with SC T that required levothyroxine supplementation. SC T includes recombinant human hyaluronidase to facilitate tissue penetration of the drug. This enzyme may alter the thyroid gland stroma and facilitate the development of thyroid disorders. Thyroid function tests are recommended in patients on SC T. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Rodrigo S & #225;nchez-Bayona Maria Angeles Garcia del Barrio Estibaliz Alegre Oscar A Fernandez-Hidalgo Marta Santisteban Eslava Source Type: research

Acute myeloid leukemia and myelofibrosis: Simultaneous transformation of essential thrombocythemia during treatment with hydroxyurea
We describe a rare case of a 79-year-old female developing disseminated intravascular coagulation due to the transformation of ET to both AML and myelofibrosis while being treated with hydroxyurea for 8 years. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Swarna Sri Nalluru Orhan Efe Yayan Chen Nitin Trivedi Source Type: research

Epiganthus presenting as respiratory distress in a male neonate: A rare case report
Naveen Kumar, Charanjeet Ahluwalia, Gaurav Singla, Swati SinglaJournal of Cancer Research and Therapeutics 2022 18(4):1177-1179An epignathus is an extremely rare form of oropharyngeal teratoma that arises from the oral cavity, most commonly from the palate and is associated with a high mortality secondary to airway obstruction in the neonatal period. It predominantly occurs in females. Here, we are presenting a case of giant epignathus in a male baby with associated cleft palate. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Naveen Kumar Charanjeet Ahluwalia Gaurav Singla Swati Singla Source Type: research

Choroid, a unique site for metastasis in Marjolin & #39;s ulcer
Amit Bagur Lokesh, Rakesh Kumar, N Saheer, Amar BhatnagarJournal of Cancer Research and Therapeutics 2022 18(4):1174-1176 Marjolin is an aggressive malignancy, which shows initial local aggression, followed by the rapid regional and distant dissemination during the latter part of its growth. Metastasis to the uveal tract, although infrequent, is usually secondary to the malignancies of the breast and lung. Marjolin's ulcer metastasizing to choroid is quite rare and unheard of. We intend to report one such case here. Here, we present a case report of a 55-year-old male, who developed Marjolin's ulcer ...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Amit Bagur Lokesh Rakesh Kumar N Saheer Amar Bhatnagar Source Type: research

Fibromatosis mimicking relapse of a neuroendocrine tumor at 68Ga-DOTATOC positron-emission tomography/computed tomography
We report the case of a female patient with a history of neuroendocrine tumor, who underwent 68Ga-DOTATOC positron-emission tomography/computed tomography (PET/CT), showing increased focal abdominal uptake suggestive of disease relapse. Histological examination revealed typical findings of fibromatosis. These findings indicate the expression of staining for somatostatin receptors (SSTRs) on fibromatosis cell surface and suggest to include fibromatosis among the potential causes of false-positive results at 68Ga PET/CT. Moreover, SSTRs expressed in desmoid tumors could be further investigated as a therapeutic target. (Sourc...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Elena Trevisi Ivan Facilissimo Stefano Taraglio Maria Pia Brizzi Source Type: research

Mucinous spindle and tubular renal cell cancer: A rare variant of renal cell cancer
We report our experience with a case of mucinous tubular spindle cell carcinoma involving the kidney. A 61-year-old female presented with a palpable left renal lump of 12 cm in size. Computed axial tomography scan revealed a well-circumscribed mass of 11 cm involving the lower pole of the left kidney. She underwent left open radical nephrectomy. The cut section revealed a well-circumscribed tumor with yellowish-white variegated areas measuring 11 cm × 8 cm × 7 cm. Histopathological diagnosis of mucinous tubular spindle cell carcinoma of the kidney was given, and the patient responded well after the ...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Malay Bajpai S Pooja Mayurika Tyagi Abhishek Pathre Source Type: research

Multiple muscle involvement in relapsed multiple myeloma: A rare case
Muzeyyen Aslaner AK, Rabiye Uslu ErdemirJournal of Cancer Research and Therapeutics 2022 18(4):1165-1167 Although extramedullary involvement in multiple myeloma (MM) emerges in various organs, muscle involvement is rarely seen and is associated with poor prognosis. It is aimed to discuss the treatment strategy in such a rare case with multiple muscle involvement in relapsed MM. Because the response to treatment is short-lived and the prognosis is poor in extramedullary involvement, effective and dynamic treatment methods for bridging should be used for clinical trials and hematopoietic stem cell transplantation. (Source: ...
Source: Journal of Cancer Research and Therapeutics - September 22, 2022 Category: Cancer & Oncology Authors: Muzeyyen Aslaner AK Rabiye Uslu Erdemir Source Type: research