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Predictive value of hepatic venous pressure gradient and efficacy and significance of early PTVE for gastrointestinal bleeding after TACE for liver cancer
Conclusion: HVPG can accurately evaluate gastrointestinal bleeding after TACE in patients with liver cancer. Early PTVE can significantly lower the risk of gastrointestinal bleeding and help TACE control tumor progression in patients with an HVPG >16 mmHg or >20 mmHg. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Jian Wei Yuefeng Hu Jianan Yu Chao Yin Guang Chen Long Jin Source Type: research

Comprehensive analysis of clinicalf eatures, treatment options, overall survival, and prognostic factors in lymphoma cell leukemia patients: A retrospective study
Conclusion: This study gives an overview of the treatment and prognosis of LCL, which provides additional information for the management of LCL. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Ya Kang Kun Fang Mengchang Wang Source Type: research

CASP4 and CASP8 as newly defined autophagy-pyroptosis-related genes associated with clinical and prognostic features of renal cell carcinoma
Conclusion: CASP4 and CASP8 were autophagy-pyroptosis-related genes associated with immunotherapy in RCC. CASP4 and CASP8 were identified as potential targets and effective prognostic biomarkers for RCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Tao Li Ning Liu Guangyuan Zhang Ming Chen Source Type: research

Pancreatic intra-arterial infusion chemotherapy for the treatment of patients with advanced pancreatic carcinoma: A pilot study
Conclusions: In this study, the dose of the chemotherapeutics and the schedule of the transcatheter pancreatic arterial chemotherapy perfusion were shown to be safe, well-tolerated, and effective for the relief of clinical symptoms and CBR. These advantages can quickly establish the treatment belief and improve patient quality of life. This regimen requires further investigation in patients with advanced pancreatic carcinoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Nan Wang Jingwen Xu Gang Wang Pikun Cao Xin Ye Source Type: research

Reminiscence therapy involved care programs as an option to improve psychological disorders and patient satisfaction in elderly lung cancer patients: A randomized, controlled study
Conclusion: RTICP, considered as an optional psychological intervention, enhances cognitive functions, alleviates anxiety and depression feelings, and elevates satisfaction among elderly lung cancer patients. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Qingfeng Guo Tianzhu Li Te Cao Chongyi Ma Source Type: research

Association between circular stapler size and anastomotic leakage after laparoscopic low anterior resection for rectal cancer
Conclusion: Choosing a smaller-diameter circular stapler may reduce the incidence of AL after laparoscopic LARfor rectal cancer without increasing the incidence of anastomotic stenosis. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Yugang Jiang Hongyuan Chen Meng Kong Dong Sun Hongguang Sheng Source Type: research

Investigating the effect of ARHGEF10L gene on tumor growth in gastric cancer in a nude mouse model using quantitative MRI parameters
Conclusions: The ADC and D values of the quantitative IVIM imaging parameters can be used to effectively assess the growth of gastric cancer in nude mice, suggesting that ARHGEF10L may promote the growth of tumor cells. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Junyi Tang Xuping Zhang Huan Chang Dawei Wang Source Type: research

Tumor-suppressive role of microfibrillar associated protein 4 and its clinical significance as prognostic factor and diagnostic biomarker in hepatocellular carcinoma
Conclusions: MFAP4 expression was significantly lower both in sera and tissue of HCC patients. MFAP4 can serve as molecular marker for HCC diagnosis and prognosis. Additionally, MFAP4 acted as an important HCC tumor suppressor by inducing S phase arrest, and promoting apoptosis, cell migration, and invasion. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Jie Li Jianguo Wang Zhikun Liu Haijun Guo Xuyong Wei Qiang Wei Shusen Zheng Xiao Xu Source Type: research

The efficacy of postoperative radiotherapy for patients with non-small cell lung cancer: An updated systematic review and meta-analysis
Zexu Wang, Baixia Yang, Ping Zhan, Li Wang, Bing WanJournal of Cancer Research and Therapeutics 2022 18(7):1910-1918 The controversy over the efficacy of postoperative radiotherapy (PORT) has existed for a long time. The present study reassessed the overall survival (OS) and disease-free survival (DFS) data to investigate whether PORT can improve survival in resectable non-small cell lung cancer (NSCLC) patients. The following databases were used to perform literature search: PubMed, Web of Science, China National Knowledge Infrastructure (CNKI), and Embase (from January 1, 1986 to July 5, 2021). The results of overall su...
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Zexu Wang Baixia Yang Ping Zhan Li Wang Bing Wan Source Type: research

Analysis of risk factors related to acute radiation dermatitis in breast cancer patients during radiotherapy
Conclusions: ARD in response to postoperative radiotherapy in patients with breast cancer is common and mild. Clinicians and patients need to cultivate awareness of the potential risk factors involved and then intervene to alleviate skin reactions and improve the quality of life. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Di Liu Zhewen Zheng Shuyuan Zhang Chunmei Zhu Hongyan Zhang Yunfeng Zhou Source Type: research

Efficacy and safety of 2-micron laser versus conventional trans-urethral resection of bladder tumor for non-muscle-invasive bladder tumor: A systematic review and meta-analysis
Conclusion: Compared with TURBT, 2-micron laser may be safer and more effective for NMIBT management. However, these conclusions need to be validated through more high-quality RCTs because of the quality limitations and publication bias of the included studies. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Jun Gu Zexi He Zhenjie Chen Haichao Wu Mingxia Ding Source Type: research

Efficacy and adverse reactions of intra-arterial chemotherapy in patients with bladder cancer: A systematic review and meta-analysis
Junjie Ji, Yu Yao, Fengju Guan, Lijiang Sun, Guiming ZhangJournal of Cancer Research and Therapeutics 2022 18(7):1884-1893 This meta-analysis investigated the efficacies of intra-arterial chemotherapy (IAC) plus intravesical chemotherapy (IVC) versus IVC alone in patients with non–muscle-invasive bladder cancer (NMIBC), and preoperative IAC versus preoperative intravenous chemotherapy (IV) in patients with bladder cancer. We also assessed the adverse reactions (ARs) of IAC. We searched the PubMed, Embase, Cochrane Library, and Web of Science databases for English articles published before April 2021. The qual...
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Junjie Ji Yu Yao Fengju Guan Lijiang Sun Guiming Zhang Source Type: research

Microwave ablation of the lung: Comparison of 19G with 14G and 16G microwave antennas in ex vivo porcine lung
Conclusions: The ablation zone of the 19G antenna was the same as those of the 14G and 16G antennas in vitro. Thus, the 19G antenna may reduce the incidence of complications in lung tumor ablation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Hongchao Cai Hui Tian Zhigang Wei Xin Ye Source Type: research

Progress and prospects for use of cellular immunotherapy in pancreatic cancer
This article examines the advance of chimeric antigen receptor NK cell immunotherapy (CAR-NK) cell immunotherapy for pancreatic cancer research, as well as research ideas for pancreatic cancer treatment. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Jing Tian Tiankai Bai Zhiyong Zhang Xuan Zhai Kangmin Wang Xingyi Gao Bin Yan Source Type: research

Useful genes for predicting the efficacy of transarterial chemoembolization in hepatocellular carcinoma
Yuan Guo, Hongtao Hu, Shijun Xu, Weili Xia, Hailiang LiJournal of Cancer Research and Therapeutics 2022 18(7):1860-1866 Transarterial chemoembolization (TACE) is generally used to treat patients with hepatocellular carcinoma (HCC), a common and deadly cancer; however, its efficacy varies according to factors such as tumor volume, stage, serum alpha-fetoprotein level, and chosen feeding artery. In addition, gene-related factors have been recently suggested to be involved in the regulation and prediction of TACE outcomes. Accordingly, genes could serve as effective biomarkers to select patients who can benefit from TACE. Th...
Source: Journal of Cancer Research and Therapeutics - January 11, 2023 Category: Cancer & Oncology Authors: Yuan Guo Hongtao Hu Shijun Xu Weili Xia Hailiang Li Source Type: research