Journal of Cancer Research and Therapeutics This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Bone scan index on bone scintigraphy and radiation therapy for bone metastases from cancers other than prostate and breast cancers: A retrospective observational study
Conclusion: The only significant association with survival identified in this study was for age at the time of BS and at time of diagnosis of bone metastases. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Naoya Ishibashi Toshiya Maebayashi Yuki Kimura Masahiro Okada Source Type: research

Radiobiological modeling of radiation-induced acute mucosal toxicity (oral mucositis and pharyngeal mucositis): A single-institutional study of head-and-neck carcinoma
Conclusion: This study presents the fitting parameters for NTCP calculation of Grade 1 and Grade 2 ARI toxicity for the endpoint of oral and pharyngeal mucositis. The provided nomograms of volume versus complication and dose versus complication for different grades of oral mucositis and pharyngeal mucositis help radiation oncologists to decide the limiting dose to reduce the acute toxicities. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Balbir Singh Gaganpreet Singh Arun Singh Oinam Vivek Kumar Rajesh Vashistha Manjinder Singh Sidhu Maninder Singh Source Type: research

Development and validation of an indigenous, radiobiological model-based tumor control probability and normal tissue complication probability estimation software for routine plan evaluation in clinics
Conclusion: We created simple software RBMODELV1 which can be used as a research tool as well as decision support system. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Ganeshkumar Patel Abhijit Mandal Avinav Bharati Sunil Choudhary Ritusha Mishra Ankur Mourya Source Type: research

Is hypermethylation of SOX1 gene an independent prognostic marker in surgically resected non-small cell lung cancer ?
Conclusion: Our study shows that SOX1 promoter hypermethylation in NSCLC tumors is significantly associated with inferior survival, showing promise as a useful prognostic biomarker in patients with NSCLC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Milica Kontic Dragana Jovanovic Izidor Kern Heather H Nelson Svetlana Bojic Miodrag Ognjanovic SImona Ognjanovic Source Type: research

Histopathological and immunohistochemical features of 14 peritoneal mesotheliomas with clinical outcomes and recent updates
Conclusion: MPMs are diagnosed with a combination of clinicopathological features and optimal IHC markers. Their differentiation from EOCs and other metastatic carcinomas is imperative in view of significant treatment implications. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Srushti Karmarkar Bharat Rekhi Kedar K Deodhar Santosh Menon Source Type: research

Controlling non small cell lung cancer progression by blocking focal adhesion kinase-c-Src active site with Rosmarinus officinalis L. phytocomponents: An in silico and in vitro study
Conclusion: In silico and in vitro studies confirmed that phytocomponents present in hydroalcoholic extract of R. officinalis L. could effectively block the active site of target proteins and thus controlled cell proliferation on NSCLC cells, suggesting herb as an effective alternative medicine for the treatment of NSCLC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Hyacinth N Highland Monica B Thakur Linz-Buoy George Source Type: research

Preoperative neutrophil-to-lymphocyte ratio and platelet-to-lymphocyte ratio are correlated with tumor & #8211;node & #8211;metastasis stages in patients with non-small cell lung cancer
Conclusion: The levels of preoperative NLR and PLR were capable of indicating advanced TNM stages. According to the CNP index, patients were divided into three risk groups with different significance. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Han Cheng Sandeep Bhushan Na Li Zongwei Xiao Ke Gao Source Type: research

Protective effect of pycnogenol against gamma radiation-induced lung injury in rat: DNA damage, lipid peroxidation, antioxidant levels, and histopathological changes
Conclusion: We demonstrate that 300 mg/kg of pycnogenol might provide significant protection against deleterious effects from whole-body ionizing radiation on the lung tissue. P300+ γ-ray group was significantly reduced radiation-induced lung injury and was possible to observe significantly preservation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Fazile Canturk Tan Arzu Hanim YAY O & #287;uz Galip Yildiz Dilek Kaan Source Type: research

BV6 enhances apoptosis in Lung cancer cells by ameliorating caspase expressions through attenuation of XIAP, cIAP-1, and cIAP-2 proteins
Conclusions: The result showed that BV6 treatment reduced the level of mRNA of XIAP, cIAP-1, and cIAP-2 and increased the gene expression of caspase-6 and caspase-7 in NCI-H23 cell line. Therefore, the study revealed that BV6 could be used in future as additional therapeutics in lung cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Irfan Ahmad Ayed A Dera Safia Irfan Prasanna Rajagopalan Mirza Masroor Ali Beg Mohammad Y Alshahrani Mushtaq Ahmad Mir Mohammed Abohashrh Mohammad Mahtab Alam Shadma Wahab Amit Kumar Verma Saurabh Srivastava Source Type: research

Correlation of digital rectal examination and serum prostate-specific antigen levels for detection of prostate cancer: Retrospective analysis results from a tertiary care urology center
Conclusion: Suspicious DRE was significantly associated with detection of prostate cancer across all PSA levels. Patients with PSA <4 can harbor prostate malignancy and such cases can be detected by use of DRE in screening of all patients with LUTS. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Debansu Sarkar Pritesh Jain Piyush Gupta Dilip Kumar Pal Source Type: research

Evaluation of clinically significant prostate cancer using biparametric magnetic resonance imaging: An evolving concept
Conclusions: Both bp-MRI and mp-MRI have high sensitivity, specificity, and diagnostic accuracy and were nearly identical in the detection of CS PCa with no significant advantage of DCE images. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Manik Mahajan Vikrant Gupta Puneet Gupta Poonam Sharma Deepak Abrol Source Type: research

Preoperative neutrophil & #8211;lymphocyte ratio/platelet & #8211;lymphocyte ratio: A potential and economical marker for renal cell carcinoma
Conclusion: NLR/PLR values can become part of routine investigations for all RCC patients. The values may help to estimate pathological outcomes, chance of recovery, recurrence, and survival rates. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Deepika Chandrasekaran Sandhya Sundaram K Maheshkumar N Kathiresan R Padmavathi Source Type: research

Safety of uro-oncology practice and robot-assisted surgery during the peak of COVID-19 pandemic: A report from India
Conclusions: We can continue treating needy cancer patients with minimal risk by taking all precautions. Our initial experience of managing uro-oncology cases during this pandemic is encouraging. Robotic surgeries can be safely performed. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Preetham Dev TB Yuvaraja Santosh S Waigankar Sharmila Ranade Abhinav P Pednekar Varun Agarwal Archan Khandekar Naresh Badlani Ashish Asari Source Type: research

Retinoblastoma: A review of clinical profile at a regional cancer center in Northwest India
Conclusion: The study showed a dire need for timely detection and treatment of retinoblastoma which is possible with improved awareness and better accessibility to health-care facilities. It also revealed a decrease in histopathological risk factors with chemoreduction. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Vimla Beniwal Guncha Maheshwari Surender Beniwal Aditya Dhanawat Pankaj Tantia Pramila Adlakha Source Type: research

Malignant transformation in low-grade astrocytoma for long-term monitoring
Conclusion: In individuals with LGA, MT dramatically altered the disease's natural history to a poor prognosis. The present study's analysis of the clinical features of patients indicated supratentorial LGA, a midline shift greater than 5 mm, and the degree of resection as risk factors for MT. The more extensive the resection, the greater the reduction in tumor load and MT. In addition, more molecular study is necessary to elucidate the pathophysiology of MT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - November 16, 2022 Category: Cancer & Oncology Authors: Thara Tunthanathip Source Type: research