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Cervical gestational trophoblastic neoplasia: A rare form of gestational trophoblastic disease
We present a case of 26-year-old woman, P0 + 3 (previous 3 abortions) who presented to us with a history of vaginal bleeding postuterine evacuation after 2 months of incomplete abortion. After clinical, radiological assessment and high human chorionic gonadotropin (hCG) titers, the patient was diagnosed as a case of cervical GTN. Risk assessment by the WHO prognostic scoring system was done and “Low Risk” was assigned to her. She was given total nine cycles of single agent chemotherapy including two consolidation cycles after normalization of hCG titers which patient tolerated well and ...
Source: Journal of Cancer Research and Therapeutics - July 25, 2022 Category: Cancer & Oncology Authors: Shyam Pyari Jaiswar Monica Agrawal Sujata Deo Sumaiya Saad Source Type: research

Intracranial hemorrhages associated with meningiomas: Own experience and literature review
Zygmunt Siedlecki, Karol Nowak, Sebastian Grzyb, Maciej ŚniegockiJournal of Cancer Research and Therapeutics 2022 18(3):820-826 Intracranial hemorrhage associated with meningioma is rare. Relatively, few such cases are described in the source literature, and it is estimated that intracranial meningiomas presenting with hemorrhage account for about one percent of all meningiomas. Hemorrhage can occur in both meningioma tissue and on the tumor surface. It can lead to intracerebral, subdural and subarachnoid hematoma. This can in turn cause high intracranial pressure with rapid neurological deterioration. Urgent ...
Source: Journal of Cancer Research and Therapeutics - July 25, 2022 Category: Cancer & Oncology Authors: Zygmunt Siedlecki Karol Nowak Sebastian Grzyb Maciej & #346;niegocki Source Type: research

Multifocal primary pseudomyogenic hemangioendothelioma of bone managed with denosumab: A rare case with diagnostic and therapeutic challenge
We present a rare case of PMH of primary bone with multifocal bony disease in a 23-year-old male who presented with severe bone pains. The patient has been managed with four weekly denosumab, and the disease is stable with symptomatic relief after 6 months. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 25, 2022 Category: Cancer & Oncology Authors: Sunil Pasricha Anila Sharma Manish Pruthi Garima Durga Ankush Jajodia Gurudutt Gupta Meenakshi Kamboj Manoj Gupta Anurag Mehta Source Type: research

Pediatric extremity rhabdomyosarcoma treated with re-brachytherapy in recurrent setting
We report the case of pediatric extremity RMS treated with re-brachytherapy in recurrent setting. A 4-year-old boy diagnosed with RMS of right upper arm underwent local excision of the lesion. Postoperative magnetic resonance imaging showed suspicious residual lesion. Revision surgery followed by brachytherapy with 30 Gy in 10 fractions twice a day over 5 days was delivered. The child developed local recurrence after 12 months. Reexcision and re-irradiation with brachytherapy were done delivering 27 Gy in 9 fractions twice a day over 5 days. The child is disease-free 18 months posttreatment with no significant disparity in...
Source: Journal of Cancer Research and Therapeutics - July 25, 2022 Category: Cancer & Oncology Authors: Ankita Rungta Kapoor Manish Chandra Rajendra Bhalavat Chetna Bakshi Chetan Anchan Pratibha Bauskar Saurabh Markana Source Type: research

Signet ring cell lymphoma of follicular type with BCL2 gene rearrangement: A rare case with a short review of literature
Pritinanda Mishra, Amit Kumar Adhya, Madhabananda Kar, Mayur Parihar, Swagatika Samal, Mukund SableJournal of Cancer Research and Therapeutics 2022 18(3):807-811 A case of signet ring cell lymphoma of presacral lymph node is reported. The patient was diagnosed as follicular lymphoma on the basis of clinical and laboratory features, including immunohistochemistry (IHC) and gene rearrangement studies. Light microscopy examination showed neoplastic atypical cells with signet ring cell morphology in core biopsy of lymph node that stained for B-cell markers by IHC. In addition, the neoplastic cells expressed CD20, CD10, BCL-2,...
Source: Journal of Cancer Research and Therapeutics - July 25, 2022 Category: Cancer & Oncology Authors: Pritinanda Mishra Amit Kumar Adhya Madhabananda Kar Mayur Parihar Swagatika Samal Mukund Sable Source Type: research