Erratum: Multiple MicroRNAs synergistically promote tolerance to epidermal growth factor receptor-targeted drugs in smoked lung cancer therapies
Journal of Cancer Research and Therapeutics 2020 16(5):1196-1196 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Source Type: research

Rechallenge of camrelizumab in non-small-cell lung cancer patients treated previously with camrelizumab and microwave ablation
We report the rechallenge of camrelizumab therapy in two patients previously treated with microwave ablation (MWA) and camrelizumab. Although objective responses were achieved, camrelizumab therapy was discontinued because of the development of immune-related pneumonia (IRP). Treatment with camrelizumab was reinitiated after the patients recovered from IRP. The reoccurrence of more severe IRP necessitated additional corticosteroid therapy. The rechallenge of camrelizumab in patients treated with MWA plus camrelizumab regimen and who developed IRP should be cautious. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Zhigang Wei Xia Yang Xin Ye Source Type: research

Safety and efficacy of the combination therapy of transcatheter arterial chemoembolization and ablation for hepatocellular carcinoma with inferior vena cava tumor thrombus: A consecutive case series
This study was designed to propose a classification of inferior vena cava tumor thrombus (IVCTT) and retrospectively evaluate the safety and efficacy of the combination therapy of transcatheter arterial chemoembolization (TACE) and sequential percutaneous ablation for hepatocellular carcinoma (HCC) with IVCTT. All HCC patients with IVCTT who underwent the combination therapies of TACE and sequential percutaneous ablation therapy between January 2015 and December 2017 in Beijing Youan Hospital were included in the study. The demographic, clinical, and pathological data were recorded. The response rate and overall survival (...
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Bozhi Liu Wei Li Jiasheng Zheng Source Type: research

Seven case reports on the prevention of hemorrhage after percutaneous computed tomography-guided core-needle biopsy of the spleen
In this study, we reported seven patients who underwent diagnostic evaluation through core-needle biopsy (CNB) of the spleen. After biopsy, gelatin sponge particles mixed with hemocoagulase were gradually injected using a coaxial introducer needle. One patient received microwave ablation following the CNB. All patients were followed up by computed tomography to rule out bleeding or accidental injuries both immediately after the biopsy and within 24 h. Adequate specimens for pathologic examination were obtained from all patients, and the biopsy technical success rate was 100%. No serious complications were observed in o...
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Run-Qi Guo Xiao-Guang Li Source Type: research

Chemotherapy combined with apatinib for the treatment of desmoplastic small round cell tumors: A case report
In this study, we administered apatinib in combination with chemotherapy to achieve good disease control. This is a 31-year-old male who presented with upper abdominal pain, nausea, and anorexia for over a month. Imaging revealed multiple solid masses and ascites in the liver and abdominal cavity. He was diagnosed as having cholangiocarcinoma with metastasis to the liver, both lungs, bone, and multiple lymph nodes in the neck, abdominal and pelvic cavity, retroperitoneum, and palpitate angle, based on a percutaneous biopsy of the liver and an abdominal mass, and other examinations. Computed tomography revealed disease prog...
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Yang Tian Xiankui Cheng Yanqing Li Source Type: research

Image smoothing using regularized entropy minimization and self-similarity for the quantitative analysis of drug diffusion
Conclusions: Experiments on simulated and real images reveal that the proposed method obtains better image restorations compared with some state-of-the-art methods, where most information is recovered and few artifacts are produced. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Lu Wang Xiangbin Meng Bin Liu Shenghai Liao Shibing Xiang Weifeng Zhou Shujun Fu Yixiao Li Yuliang Li Hongbin Han Source Type: research

Transcatheter arterial chemoembolization combined with low-dose apatinib in the treatment of unresectable hepatocellular carcinoma in elderly patients: Efficacy and safety
Conclusions: TACE combined with low-dose apatinib provides an alternative treatment option for elderly patients with unresectable HCC. Our clinical study has proven its safety and efficacy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Song Liu Guangsheng Zhao Guangji Yu Nannan Guo Yuewei Zhang Qiang Li Zhe Wang Source Type: research

Prognostic value and functional bioinformatic analysis of spindle- and kinetochore-associated protein 1 in stage IIA esophageal squamous cell carcinoma
Conclusion: The results of this study demonstrate that SKA1 may act as a prognostic biomarker for stage IIA ESCC. Combined with the bioinformatic analysis, SKA1 could potentially serve as a therapeutic target for ESCC. Conclusion: The results coming from the present study demonstrated that SKA1 may act as a prognostic biomarker for stage IIA ESCC. Combined with the bioinformatic analysis, SKA1 could serve as a potential therapeutic target for ESCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Dongxin Hu Mingyan Zhang Zhongmin Peng Source Type: research

Magnetic resonance imaging-guided microwave ablation of hepatic malignancies: Feasibility, efficacy, safety, and follow-up
Conclusion: MRI-guided ablation is feasible and effective for planning and evaluating MWA in hepatic malignancies. The available clinical data strongly support the advantages of the assessment of tumors through 3D imaging versus routine axial images. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Nannan Yang Ju Gong Linyan Yao Chen Wang Jun Chen Jiangwen Liu Zhongmin Wang Jian Lu Source Type: research

Renal pseudotumor: A new challenge in the diagnosis of immunoglobulin G4-related disease
Conclusion: We should consider pseudotumor-like IgG4-RD as a differential diagnosis for solitary renal lesion although the incidence is low. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Qian Wu Na Zhao Xia Wang Hongsheng Sun Limin Zhang Source Type: research

Thermal field study of ceramic slot microwave ablation antenna based on specific absorption rate distribution function
Conclusion: The CSMW ablation antenna had a greater long diameter, transverse diameter, and volume regarding the ablation morphology than the PSMW ablation antenna, and the thermal field morphology obtained based on the rapid simulation algorithm had a high accuracy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Yonggang Wang Ronghua Jiang Jie Yu Source Type: research

Hemoglobin, albumin, lymphocyte, and platelet score and neutrophil-to-lymphocyte ratio are novel significant prognostic factors for patients with small-cell lung cancer undergoing chemotherapy
Conclusion: HALP and NLR were the independent prognostic factors of OS for SCLC patients undergoing chemotherapy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Ning Yang Xiao Han Jinyu Yu Weibin Shu Feng Qiu Junqing Han Source Type: research

Evaluation of the correlation between infrared thermal imaging-magnetic resonance imaging-pathology of microwave ablation of lesions in rabbit lung tumors
Conclusions: MWA of malignant lung tumors had specific MRI characteristics that were comparable with postoperative pathology. Infrared thermal imaging combined with MRI can be used to evaluate the extent of thermal damage to lung VX2 tumors. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Jian Chen Xiao-Nan Lin Xian-Hua Miao Jin Chen Rui-Xiang Lin Huai-Ying Su Jia-Bin Lin Zheng-Yu Lin Source Type: research

Feasibility of computed tomography-guided irreversible electroporation for porcine kidney ablation
Conclusion: IRE was essentially safe, however further studies on tumor ablation using several different animal models are needed. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Tong-Yin Zhu Jing Ai Chun-Hui Nie Guan-Hui Zhou Xin-Hua Chen Yue-Lin Zhang Tan-Yang Zhou Sheng-Qun Chen Bao-Quan Wang Shu-Sen Zheng Li-Ming Wu Jun-Hui Sun Source Type: research

Should the Oddis sphincter be retained ? A clinical analysis of biliary metal stent implantation in patients with malignant obstructive jaundice
Conclusion: Leaving the Oddis sphincter untouched during biliary stent placement can reduce the incidence of postoperative complications, while there was no effect on stent patency or jaundice relief. Therefore, it is recommended to preserve the Oddis sphincter when the stenosis is more than 3 cm above the duodenal papilla. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: ChangFu Liu WenGe Xing TongGuo Si Zhi Guo HaiPeng Yu Source Type: research

Insufficient radiofrequency ablation promotes epithelial & #8211;mesenchymal transition mediated by interleukin-6/signal transducer and activator of transcription 3/Snail pathway in the H22 cells
Conclusions: Insufficient ablation performed at low temperature successfully induces EMT and promotes tumor aggressiveness, which is mediated by the IL-6/STAT3/Snail pathway in both cell and mouse models. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Tong Zhou Bin Liu Yongzheng Wang Wujie Wang Haiyang Chang Dong Li Yuliang Li Zhaomin Song Source Type: research

Clinicopathologic factors associated with pathologic upstaging in patients clinically diagnosed stage T2N0M0 squamous cell esophageal carcinoma
Conclusions: In SECC diagnosed as stage T2N0M0 by CT and EUS, the incidence of postoperative pathologic upstaging increases with a large TV, high TC, high TGs, high PLR, and high number of lymph nodes examined. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Meng Li Hounai Xie Feng Zhen Hui Wang Zhongmin Peng Lin Xu Source Type: research

Endoscopic ultrasound-guided sampling using core biopsy needle for diagnosis of left-lobe hepatocellular carcinoma in patients with underlying cirrhosis
Conclusions: EUS-FNB is a sensitive and safe diagnostic modality for cirrhotic patients with suspected HCC located in the left lobe, especially those for whom percutaneous biopsy is contraindicated. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Fen Chen Haiwei Bao Zhuang Deng Qiyu Zhao Guo Tian Tian-An Jiang Source Type: research

Magnetic resonance-guided ablation of liver tumors: A systematic review and pooled analysis
Conclusions: MR-guided ablation is a practicable alternative treatment for liver tumors, especially MR-guided RFA and MWA, which have high rates of CA and low occurrences of complications. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Jianfeng Xiang Ming Liu Rongbin Lu Ligang Wang Yujun Xu Xiangmeng He Roberto Blanco Chengli Li Source Type: research

Evaluating the efficacy and safety of ultrasound-guided percutaneous microwave ablation for the treatment of adrenal metastasis
Conclusions: Percutaneous US-guided MWA is safe and effective in terms of local control and survival of adrenal metastasis. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Yuanjin Gao Lili Zheng Ping Liang Zhigang Cheng Zhiyu Han Shui-Lian Tan Xiaoling Yu Source Type: research

Biomembrane formation after radiofrequency ablation prevents bone cement extravasation during percutaneous vertebroplasty for treating vertebral metastases with posterior margin destruction: An animal study
Conclusions: The biomembrane barrier formed at the tumor edge after RFA can prevent bone cement leakage into the spinal canal, reducing spinal cord injury and prolonging the survival time. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Zhe Yu Shilin Tian Wei Wang Yuliang Li Yongzheng Wang Source Type: research

Long-term outcomes of patients with papillary thyroid cancer who did not undergo prophylactic central neck dissection
Conclusion: The outcomes of patients with clinically negative lymph nodes in the central compartment were favorable without prophylactic CND. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Hui Huang Ligang Wu Wensheng Liu Jie Liu Yang Liu Zhengang Xu Source Type: research

A randomized controlled Phase II trial of vinorelbine plus capecitabine versus docetaxel plus capecitabine in anthracycline-pretreated women with metastatic breast cancer
Conclusion: NX and TX regimens are both alternative treatments for patients with anthracycline- and taxane-resistant advanced breast cancer, but the safety profile was more favorable and manageable with the NX regimen. Trial Registrations: ClinicalTrials.gov NCT01635465. Registered 09 July 2012. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Shufen Li Wenjing Meng Jibo Zhang Xiaojuan Xie Chunfang Hao Yongsheng Jia Zhongsheng Tong Source Type: research

Transarterial chemoembolization combined with apatinib versus transarterial chemoembolization alone for hepatocellular carcinoma with macroscopic vascular invasion: A propensity score matching analysis
Conclusions: TACE combined with apatinib may result in superior OS compared to TACE therapy alone for HCC patients with macrovascular invasion. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Lujun Shen Shuanggang Chen Zhiyu Qiu Han Qi Hui Yuan Fei Cao Lin Xie Qifeng Chen Wang Li Weijun Fan Source Type: research

Ultrasonic identification and regression analysis of 294 thyroid follicular tumors
Conclusion: Ultrasound can provide valuable information for the identification of follicular neoplasms, but further research in this area is still necessary. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Di Ou Jincao Yao Ju Jin Meiying Yan Kaiyuan Shi Qiuqing Zheng Chen Yang Dong Xu Source Type: research

Clinical efficacy of Mohs surgery combined with topical photodynamic therapy for facial basal cell carcinoma
Conclusion: The efficacy of Mohs surgery combining topical PDT is a definite treatment for facial basal cell carcinomas, as it reduced the tumor recurrence rate and maintained the relative integrity of the local tissues and appearance. This method could be a new effective treatment method for the facial basal cell carcinoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Junbo Zhang Yuangang Lu Xingcun Zhang Yunchuan Yang Huiling Kou Yuanyuan Wang Source Type: research

Predictive effects of a combined indicator in patients with hepatocellular carcinoma after thermal ablation
Conclusion: Elevated preablation SII-ALBI is associated with shorter OS, CSS, and RFS in patients with early-stage HCC. Our indicator showed the potential to be a supplement tool for patients with negative AFP during follow-up. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Qi Yang Xiao-ling Yu Ying Wang Zhi-gang Cheng Zhi-yu Han Fang-yi Liu Tong-gang Qian Jie Yu Ping Liang Source Type: research

Transarterial chemoembolization combined with microwave ablation versus microwave ablation only for Barcelona clinic liver cancer Stage B hepatocellular carcinoma: A propensity score matching study
Conclusions: The MWA alone group had RFS and OS comparable to that of the TACE-MWA group. TACE-MWA was effective in controlling LTP in patients with a single tumor. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Xin Li Baohua Chen Chao An Zhigang Cheng Zhiyu Han Fangyi Liu Jie Yu Ping Liang Source Type: research

Comprehensive treatment for multicentric giant cell tumors of the pelvis and spine using apatinib: A case report and literature review
Conclusions: Comprehensive treatment including apatinib represents a potential new treatment strategy for inoperable GCTB, with tolerable side effects. However, further clinical trials are now necessary to confirm an effective dose and determine the efficacy and safety of apatinib in the treatment of GCTB. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Jun Li Jun Zhou Yuntong Liu Xiaogang Sun Wei Song Source Type: research

The application of magnetic resonance imaging-guided microwave ablation for lung cancer
Conclusions: As a minimally invasive method for treating lung tumors, MRI-guided MWA requires fewer localization scans, a shorter MWA duration, no radiation, real-time observation of the curative effect, and it prevents overtreatment. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Liu Nian-Long Yang Bo Chen Tian-Ming Feng Guo-Dong Yin Na Wang Yu-Huang Shen Wen-Rong Chen Shi-Lin Source Type: research

Effectiveness of radiofrequency ablation therapy for patients with unresected Stage IA non-small cell lung cancer
Conclusion: RFA improves unresected stage IA NSCLC patient survival. Our results are limited by the retrospective nature of the study; however, we believe that our findings are noteworthy for recommending local ablative therapy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Ming Li Yingyi Qin Aihong Mei Changhui Wang Lihong Fan Source Type: research

Laparoscopic partial splenectomy of benign tumors assisted by microwave ablation
Conclusion: Microwave ablation is worthy of clinical application in laparoscopic partial spleen resection as it is safe and effective with low rates of bleeding and fast recovery. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Qiang Li ZhiLong Liu Min Hu MaoQiang Ou KangShou Liu WeiDa Lin FeiFeng Wu MingRong Cao Source Type: research

CYP17 inhibitors improve the prognosis of metastatic castration-resistant prostate cancer patients: A meta-analysis of published trials
Conclusion: This research showed that CYP17 inhibitors had a significant improvement on prognosis of patients with mCRPC within a relative safety profile both in pre- and post-chemotherapy trials. These expected results provide evidence for the use of CYP17 inhibitors to treat mCRPCs. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Qi Cao Peng Bai Deyao Shi Jiali Liao Hangchuan Shi Yifei Xing Ke Chen Xiaoping Zhang Source Type: research

Robot-assisted versus laparoscopic surgery for rectal cancer: A systematic review and meta-analysis
Conclusion: Robot-assisted surgery for rectal cancer showed longer operative time, lower conversion, faster bowel function recovery rates, and shorter hospital stay, and similar oncological outcomes compared to laparoscopic surgery. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Xiaowei Wang Gaoyang Cao Weifang Mao Weifeng Lao Chao He Source Type: research

Interventional radiology under the era of coronavirus disease 2019: Recommendations from the Chinese College of Interventionalists
Hai-Dong Zhu, Bin Xiong, Zhong-Zhi Jia, Jian Lu, Zhong-Min Wang, Gao-Jun TengJournal of Cancer Research and Therapeutics 2020 16(5):974-978 The pandemic of coronavirus disease 2019 (COVID-19) has become a major public health threat to the whole world. Although the control of COVID-19 has been in the forefront of interventional practice, most interventional radiologists (IRs) are not equipped adequately to cope with such a crisis. In this review, we share our experience from Chinese IRs' perspective, report on the acute measures instituted within interventional radiology (IR) units, and give recommendations to the prev...
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Hai-Dong Zhu Bin Xiong Zhong-Zhi Jia Jian Lu Zhong-Min Wang Gao-Jun Teng Source Type: research

Expert consensus workshop report: Guidelines for preoperative assisted localization of small pulmonary nodules
Baodong Liu, Chundong GuJournal of Cancer Research and Therapeutics 2020 16(5):967-973 Along with increasing incidence of operable small pulmonary nodules, it becomes difficult to localize nodules via palpation. Accurate localization of small pulmonary nodules has remained a big challenge in lung surgery. Therefore, several techniques for preoperative localizing small pulmonary nodules have evolved, but the advantages and disadvantages of each method remain unclear. We reviewed computed tomography-guided percutaneous and bronchoscopic preoperative assisted localization for small pulmonary nodules. Original, peer-reviewed,...
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Baodong Liu Chundong Gu Source Type: research

Expert consensus workshop report: Guidelines for thermal ablation of thyroid tumors (2019 edition)
Dong Xu, Minghua Ge, Ankui Yang, Ruochuan Cheng, Hui Sun, Hongcheng Wang, Jianquan Zhang, Zhigang Cheng, Zeyu Wu, Zhongmin Wang, Bo Zhai, Yin Che, Lin Chen, Liyu Chen, Wen Cheng, Gang Dong, Peiyan Duan, Weijun Fan, Jian Fei, Rongzhan Fu, Meizhuo Gao, Pintong Huang, Tianan Jiang, Jian Kuang, Honghao Li, Ping Li, Xinying Li, Zhihui Li, Man Lu, Yukun Luo, Huadong Qin, Jianwu Qin, Zhuo Tan, Lina Tang, Zhaohui Wang, Shurong Wang, Xiaoping Wang, Gaosong Wu, Xiaoyan Xie, Haimiao Xu, Detao Yin, Xinguang Qiu, Y Jichun, Jianjun Yu, Weiwei Zhan, Fujun Zhang, Junqing Zhang, Rongqin Zheng, Xiangqian Zheng, Yuanyi Zheng, Youhua Zhu, Yin...
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Dong Xu Minghua Ge Ankui Yang Ruochuan Cheng Hui Sun Hongcheng Wang Jianquan Zhang Zhigang Cheng Zeyu Wu Zhongmin Wang Bo Zhai Yin Che Lin Chen Liyu Chen Wen Cheng Gang Dong Peiyan Duan Weijun Fan Jian Fei Rongzhan Fu Meizhuo Gao Pintong Huang Tianan Jian Source Type: research

TATI modality: A new perspective on the treatment of advanced hepatocellular carcinoma
Xin Li, Ping Liang, Xin YeJournal of Cancer Research and Therapeutics 2020 16(5):957-959 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 29, 2020 Category: Cancer & Oncology Authors: Xin Li Ping Liang Xin Ye Source Type: research

& #8220;Choosing Wisely & #8221; for cancer care in India
CS Pramesh, Harit Chaturvedi, Vijay Anand Reddy, Tapan Saikia, Sushmita Ghoshal, Mrinalini Pandit, K Govind Babu, KV Ganpathy, Dhairyasheel Savant, Gunita Mitera, Richard Sullivan, Christopher M Booth, On behalf of the National Cancer Grid of India Journal of Cancer Research and Therapeutics 2020 16(4):955-956 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: CS Pramesh Harit Chaturvedi Vijay Anand Reddy Tapan Saikia Sushmita Ghoshal Mrinalini Pandit K Govind Babu KV Ganpathy Dhairyasheel Savant Gunita Mitera Richard Sullivan Christopher M Booth On behalf of the National Cancer Grid of India Source Type: research

Epidermal growth factor receptor-activating mutation(E746_T751>VP) in pancreatic ductal adenocarcinoma responds to erlotinib, followed by epidermal growth factor receptor resistance-mediating mutation (A647T): A case report and literature review
Girijesh Kumar Patel, Josiah B Perry, Osama Abdul-Rahim, Arthur E Frankel, Daniel Cameron, William Taylor, Rodney P Rocconi, Laith Abushahin, Cindy Nelson, Ajay P Singh, Moh'd KhushmanJournal of Cancer Research and Therapeutics 2020 16(4):950-954 Despite recent advances in treatment with multidrug chemotherapy regimens, outcomes of patients with advanced pancreatic ductal adenocarcinoma (PDAC) remain very poor. Treatment with targeted therapies has shown marginal benefits due to intrinsic or acquired resistance. Actionable mutations, while detected infrequently in patients with PDAC, are becoming increasingly used in ...
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Girijesh Kumar Patel Josiah B Perry Osama Abdul-Rahim Arthur E Frankel Daniel Cameron William Taylor Rodney P Rocconi Laith Abushahin Cindy Nelson Ajay P Singh Moh & #39;d Khushman Source Type: research

Synchronous thoracic and head-and-neck malignancies-double trouble-challenges, pitfalls, and lessons learnt
We report three cases of double primary malignancies treated at our hospital. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Kanika Sharma Sood Manisha Himthani Aditi Tanwar S Lakshmana Perumal Source Type: research

Long-term survival of a patient with programmed death ligand 1-negative lung adenocarcinoma and oligoprogressive disease treated with nivolumab and stereotactic body radiation therapy
We present the case of a complete responder to nivolumab that after a monotopic adrenal relapse received stereotactic body radiation therapy, followed by maintenance nivolumab achieving a partial response that is still ongoing. Aspects such as mechanisms of acquired resistance to PD-L1 inhibitors, the optimal management after progression, and the potential interplay between IO and RT are briefly reviewed and discussed. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Miguel J Sotelo Santiago Cabezas-Camarero Alejandro Riquelme Coralia Bueno Source Type: research

Intrathoracic hemangioma
We report the very rare case of recurrent unilateral pleural effusion in a 53-year-old male. Computed tomography (CT) scan and magnetic resonance imaging revealed a left-sided paravertebral mass at D3 level. Multiple biopsy and CT scan lead us to the diagnosis of “Angiomatous Malformation.” The lesion was excised surgically which on final histopathological report termed hemangioma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Gaurav Patel Suyash Agrawal Prakash Patil Source Type: research

Calvarial metastasis from adenocarcinoma of lung: An uncommon initial presentation diagnosed by cytology
Subrata Pal, Biswajit Biswas, Ranu Roy Biswas, Rajashree Pradhan, Abhishek SharmaJournal of Cancer Research and Therapeutics 2020 16(4):935-937 Bone metastasis from lung primary is not uncommon and about one-third of bone metastases originate from lung. However, skull bone metastasis is uncommon from lung carcinoma. Metastasis to skull bone and scalp as an initial presentation of lung carcinoma is a very rare phenomenon. We have diagnosed a case of calvarial metastasis with scalp swelling as an initial presentation of adenocarcinoma of lung by fine-needle aspiration cytology in an aged female. Radiologically, it was sugge...
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Subrata Pal Biswajit Biswas Ranu Roy Biswas Rajashree Pradhan Abhishek Sharma Source Type: research

Utility of medical thoracoscopy in diagnosis and treatment of hemothorax due to carcinoma: A case report
We reported a 76-year-old male with hemothorax who was cured by medical thoracoscopy under local anesthesia together with argon plasma coagulation. Moreover, final pathological diagnosis was acquired as pleural sarcomatoid carcinoma. The unusual manifestation under medical thoracoscopy of such a relative rare disease was also described in this paper. The medical thoracoscopy could be used successfully for hemothorax instead of treating with surgeon, especially for those who cannot tolerate procedure of operation or surgical thoracoscopy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Qing-Hua Liu Dian-Jie Lin Source Type: research

Successful treatment of nonsmall cell lung cancer patients with leptomeningeal metastases using whole brain radiotherapy and tyrosine kinase inhibitors
We report here the case of a male patient in his 60s with adenocarcinoma who underwent lobectomy of the right upper lobe. The cancer was classified as pT1bN1M0 Stage IIA, and a mutational analysis revealed the presence of an EGFR mutation. However, 6 months after standard chemotherapy, LM had developed and WBRT was administered. Gefitinib (250 mg/day) was administered after WBRT. The patient remained free of significant recurrent disease for 57 months after WBRT was administered. Combination therapy with TKIs and WBRT is associated with relatively long survival times in patients with LM. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Masakuni Sakaguchi Toshiya Maebayashi Takuya Aizawa Naoya Ishibashi Tsutomu Saito Source Type: research

Diagnostic dilemma of a thumb swelling: An unpropitious turn of events
We report a peculiar case of an adult man who presented with thumb swelling, which was later discovered to be a metastasis from renal cell carcinoma. Such cases have a sinister prognosis with a survival rate of 6–12 months from the time of diagnosis. We intend to discuss the diagnostic dilemma and treatment of acrometastases. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Seetharama B Rao Pooja K Suresh Merwyn Fernandes Laxman G G Prabhu Saraswathy Sreeram Rajendra Annappa Source Type: research

Coughing up: & #8220;Adenosquamous carcinoma lung with unusual initial presentation as an ulceroproliferative growth & #8221; - case report and review of literature
Rakesh Kumar, Gunjesh Kumar Singh, Pragya SinghJournal of Cancer Research and Therapeutics 2020 16(4):922-925 Lung carcinoma is the most common carcinoma seen in males with the skin being a rare metastatic site. Adenosquamous carcinoma as a rare histologic subtype, showing cutaneous metastasis is an unusual event with no reports in the literature till date. Skin metastasis is an alarming sign, carries poor prognosis, and is associated with shortened survival. Herein, we report a case of 60-year-old male who presented with isolated cutaneous metastasis as a chronic nonhealing ulcer over the sternal region for 3 years (unus...
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Rakesh Kumar Gunjesh Kumar Singh Pragya Singh Source Type: research

Interstitial lung disease secondary to alectinib after interstitial injury induced by crizotinib
Kyoichi Kaira, Ichiro Naruse, Kimihiro Shimizu, Takayuki AsaoJournal of Cancer Research and Therapeutics 2020 16(4):919-921 An 84-year-old male had a recurrence after surgical resection against Stage IIIA pulmonary adenocarcinoma and was treated with crizotinib due to harboring the anaplastic lymphoma kinase fusion gene. The patient exhibited crizotinib-induced interstitial lung disease (ILD), and alectinib was administered because of progressive disease. However, ILD appeared in both lungs again after alectinib treatment. This is the first case of ILD, resulting from alectinib administration after crizotinib-induced ILD....
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Kyoichi Kaira Ichiro Naruse Kimihiro Shimizu Takayuki Asao Source Type: research

A cutaneous metastasis of bronchogenic carcinoma: Milia-like lesions with dermatomal pattern
Esra Varnali, Ayse Kavak, Yasemin Özkan, Fatma Büsra KarahaciogluJournal of Cancer Research and Therapeutics 2020 16(4):917-918 Clinical presentation of cutaneous metastases is often variable. Presented case had an intriguing cutaneous metastasis of bronchogenic squamous cell carcinoma. Lesions were characterized by dermatomal pattern with milia-like papules, plaques, and nodules. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - September 14, 2020 Category: Cancer & Oncology Authors: Esra Varnali Ayse Kavak Yasemin & #214;zkan Fatma B & #252;sra Karahacioglu Source Type: research