Colonic metastasis from hepatocellular carcinoma after treated by ablation and transarterial chemoembolization manifested by intestinal obstruction: A case report and review of the literature
Mengjuan Mu, Jie Yu, Ping Liang, Xiaoling Yu, Zhigang ChengJournal of Cancer Research and Therapeutics 2021 17(3):814-817 Hepatocellular carcinoma (HCC) with gastrointestinal tract metastasis is a rare condition. Recently, we encountered one case of HCC with direct invasion to the colon, which was manifested by intestinal obstruction. The patient was an 86-year-old man who underwent multiple transarterial chemoembolization and microwave ablation treatment for HCC lesions for 10 years. Two months after last palliative microwave ablation, computed tomography showed a 7.0-cm liver tumor directly invading the hepatic flexure ...
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Mengjuan Mu Jie Yu Ping Liang Xiaoling Yu Zhigang Cheng Source Type: research

Computed tomography-guided percutaneous microwave ablation for pulmonary multiple ground-glass opacities
Guoliang Xue, Zhichao Li, Gang Wang, Zhigang Wei, Xin YeJournal of Cancer Research and Therapeutics 2021 17(3):811-813 With the wide application of low-dose computed tomography (CT) and high-resolution CT, the increasing cases of pulmonary nodules are identified through routine thoracic imaging examination, many of which are presented as multiple ground-glass opacities (GGOs). The multiple GGOs could be divided into four pathological types and usually got different combined mutation patterns, suggesting that each GGO is an independent event and should be treated separately. However, there is no established guideline to th...
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Guoliang Xue Zhichao Li Gang Wang Zhigang Wei Xin Ye Source Type: research

The combination therapy with the cytotoxic T lymphocyte-associated antigen-4 and programmed death 1 antibody-induced asthma in a patient with advanced melanoma
We report the case of a patient with advanced melanoma who developed asthma during anti-PD-1 and anti-CTLA-4 combination therapy. The patient was a 57-year-old woman enrolled in a clinical trial regarding novel CTLA-4 antibody and sintilimab treatment. The patient was diagnosed with asthma after three cycles of therapy. Subsequently, she was treated with corticosteroids, shortcostero β2 agonists, and antihistamines. The symptoms were relieved after 7 days. This is the first report of asthma in a patient treated with combination immunotherapy to the best of our knowledge. The mechanism remains to be further explored. (...
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Weiran Xu Bin Lian Chuanliang Cui Jun Guo Source Type: research

Ultrasound-guided percutaneous microwave ablation of bilateral renal cell carcinomas: Focus upon safety and efficacy
Conclusion: US-guided percutaneous MWA is a beneficial treatment for BRCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Ruimin Zhang Erpeng Qi Ping Liang Zhigang Cheng Shuilian Tan Zhiyu Han Fangyi Liu Jie Yu Xiaoling Yu Source Type: research

Combination of thermal ablation and activated functional killer cells immunotherapy for cancer: A retrospective study
Conclusion: Combination of thermal ablation and AFK cells immunotherapy is a safe and effective method for patients with malignancy. And adoptive immunotherapy with AFK cells may be helpful to prevent recurrence after thermal ablation in patients with advanced cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Yunfang Li Yuanming Li Zhixin Bie Bin Li Jie Ma Xiaoguang Li Source Type: research

A practical screening strategy for Lynch syndrome and Lynch syndrome mimics in colorectal cancer
Conclusions: Our screening strategy, which consists of clinical and molecular analyses, is expected to improve the screening efficiency and management for the LS and LS mimics. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Zhi-Gang Yao Bei-Bei Lv Hai-Yan Jing Wen-Jing Su Jia-Mei Li Hui Fan Miao-Qing Zhao Ye-Jun Qin Xi-Chao Sun Source Type: research

Trans-jugular intrahepatic portosystemic shunt in patients with hepatic cellular carcinoma: A preliminary study
Conclusion: TIPS could reduce ascites, down-regulate the Child-Pugh score, and give a chance for further anti-tumor therapy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Hong Dong Cunjing Zhang Zheng Li Haiyan Yang Yongzheng Wang Jibing Liu Bin Liu Shuzhi Mao Source Type: research

Factors influencing postembolization syndrome in patients with hepatocellular carcinoma undergoing first transcatheter arterial chemoembolization
Conclusions: Drug loading microspheres, serum albumin, and drug loading were the predictors of PES after the first TACE. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Jing-Jing He Xi-Xi Yin Ting Wang Min-Ying Chen Xi-Long Li Xin-Jing Yang Hong-Yan Shao Source Type: research

Overexpression of replication protein A3 is associated with unfavorable outcome in bladder urothelial carcinoma
Conclusions: These results of this study proved that elevated expression of RPA3 was associated with worse clinical outcome in bladder UC patients. This finding suggested that RPA3 served as a potential prognostic biomarker, which could be useful to predict cancer evolution and may represent a novel therapeutic target for the intervention of bladder UC patients. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Dingqi Sun Keqin Zhang Qiang Fu Hui Zhang Shuai Liu Haoran Wang Zhen Xu Jinhua Wang Source Type: research

Ultrasound-guided percutaneous microwave ablation for hepatocellular carcinoma originating in the caudate lobe: A pilot clinical study
Conclusions: US-guided percutaneous MWA was a safe and effective treatment. It is a promising alternative therapy for HCC originating in the caudate lobe. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Yuan Peng Dan Cui Weijian Li Ming Ding Yaoping Shi Tao Wang Donghua Shi Jiachang Chi Ping Li Bo Zhai Source Type: research

Multiregion sequencing and subclonal analysis reveal intratumoral heterogeneity in esophageal squamous cell carcinoma
Conclusions: There is significant intratumoral genomic heterogeneity in the five ESCCs, and their subclonal structure is related to spatial locations. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Dongni Gao Zicheng Zhang Qiwei Yang Baosheng Li Source Type: research

Detection significance of miR-3662, miR-146a, and miR-1290 in serum exosomes of breast cancer patients
Conclusions: Exosomal miR-3662, miR-146a, and miR-1290 may have promising predictive value and could be utilized as biomarkers for diagnosis and preventative strategy development. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Sha Li Meng Zhang Feng Xu Ying Wang Dong Leng Source Type: research

Intermediate stage hepatocellular carcinoma: Comparison of the value of inflammation-based scores in predicting progression-free survival of patients receiving transarterial chemoembolization
Conclusions: As a first-line treatment, TACE was not well suitable for all intermediate-stage HCC patients, while the PLR was a better inflammation-based score than others. Tumor size should be regarded as an essential variable in affecting intermediate-stage HCC patients' first-line treatment strategies. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Ying Liu Menting Shi Shuanggang Chen Weiqi Wan Lujun Shen Binyan Shen Han Qi Fei Cao Ying Wu Tao Huang Guanjian Chen Jinqing Mo Dongdong Ye Yinqi Zhang Ziqing Feng Weijun Fan Source Type: research

Short-term efficacy and safety of callispheres drug-loaded microsphere embolization in primary hepatocellular carcinoma
Conclusion: DEB TACE has improved short term efficacy and lower incidence of complications in primary HCC and prolongs the interval of TACE. It significantly increases the ORR, especially in patients with no extra hepatic metastasis pretreatment. DEB usage actually improves treatment efficacy and provides more benefits to patients. KEY WORDS: Drug-loaded bead-transcatheter arterial chemoembolization, hepatocellular carcinoma, microsphere embolization (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Jinpeng Li Nan Wang Congcong Shi Qingran Liu Jinlong Song Xin Ye Source Type: research

Comparative analysis of bile culture and blood culture in patients with malignant biliary obstruction complicated with biliary infection
Conclusions: It is vital to enable simultaneous bile bacterial culture and blood culture in patients with MBO complicated with biliary infection. Existing guidelines for the diagnosis and treatment of benign biliary infection are not applicable to patients with MBO complicated with biliary infection. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Chengli Wang Haipeng Yu Ji & #39;an He Mei Li Lei Zhang Yan Xu Wei Gao Xueling Yang Xiuying Guo Zhi Guo Source Type: research

The clinical efficacy of computed tomography-guided 125I particle implantation combined with arterial infusion chemotherapy in the treatment of pancreatic cancer
Conclusions: We conclude that 125I radioactive particle implantation combined with regional arterial perfusion chemotherapy is an effective and comprehensive treatment for advanced pancreatic cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Liang Yang Chuang Li Zhe Wang Jinyu Wu Jun Zhou Ruoyu Wang Source Type: research

Efficacy comparison between microwave ablation combined with radiation therapy and radiation therapy alone for locally advanced nonsmall-cell lung cancer
Conclusion: MA combined with IMRT in the treatment of locally advanced peripheral NSCLC was not inferior to the clinical effect of radiation therapy alone, and radiation lung injury incidence was also lower. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Pengyuan Song Wei Sun Min Pang Weina He Weihua Zhang Lijun Sheng Source Type: research

Prognostic nomogram for hepatocellular carcinoma patients after transarterial chemoembolization based on des- & #947;-carboxy prothrombin reactivity and modified Response Evaluation Criteria in Solid Tumors
Conclusion: DCP reactivity and mRECIST are the key predictors of prognosis in HCC patients that received TACE as their initial treatment. The nomogram constructed with these two indicators as the core could predict the OS of HCC patients after TACE and help in clinical decision-making. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Su-Ming Zhao Li-Wei Qiu Hui Zhao Wei-Wei Gu Xiao-Hu Yang Zhu-Xing Gu Rong-Feng Shi Cai-Fang Ni Source Type: research

Advantages of interstitial radioactive seed implantation for the treatment of Stage III pancreatic cancer
Conclusions: Radioactive seed implantation obviously advantageous for the treatment of Stage III pancreatic cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Baodong Gai Qingchun Li Pu Shao Dongyan Yang Source Type: research

Computed tomography-guided lung biopsy: A meta-analysis of low-dose and standard-dose protocols
Conclusions: Relative to SDCT-guided lung biopsy, an LDCT-guided approach is equally safe and can achieve comparable diagnostic efficacy while exposing patients to lower doses of radiation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Ping Zhang Jing-Mei Liu Ying-Ying Zhang Rong Hua Feng-Fei Xia Yi-Bing Shi Source Type: research

Comparison of three-dimensional-printed template-guided and traditional implantation of 125I seeds for gynecological tumors: A dosimetric and efficacy study
Conclusion: 3D-PT-guided 125I seed implantation is safe and effective in the treatment of gynecological tumors. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Weiming Kang Hongtao Zhang Yansong Liang Enli Chen Jinxin Zhao Zhen Gao Juan Wang Source Type: research

Prognostic role of programmed cell death ligand-1 expression in head and neck cancer treated with programmed cell death protein-1/programmed cell death ligand-1 inhibitors: A meta-analysis based on clinical trials
Conclusions: In summary, PD-L1–positive HNSCC patients portend favorable OS at 6 and 12 months from PD-1/PD-L1 ICIs. Increased ORR also favored to appear in PD-L1 expressors of HNC or recurrent/metastatic HNSCC who received PD-1/PD-L1 ICIs. Therefore, PD-L1 proved to be an appropriate biomarker to predict the clinical efficacy and prognosis of PD-1/PD-L1 ICIs in HNC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Zilu Huang Shuohan Zheng Shirong Ding Yinghong Wei Chen Chen Xing Liu He Li Yunfei Xia Source Type: research

Preoperative computed tomographic-guided percutaneous coil localization of pulmonary nodules: 184 Cases in Single-center
Conclusion: Preoperative CT-guided percutaneous coil localization is a safe and effective method to facilitate high success rates for both wedge and segmental resection for peripheral pulmonary nodules. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Xujian Han Zhenjia Li Hui Gu Honglu Shi Weitao Dou Ximing Wang Source Type: research

EGFR tyrosine kinase inhibitors alone or in combination with chemotherapy for non-small-cell lung cancer with EGFR mutations: A meta-analysis of randomized controlled trials
Conclusion: Our meta-analysis shows that EGFR TKIs with chemotherapy confer better OS and ORR compared to either treatment alone, similarly, the combined treatment showed better PFS and ORR profiles than the use of TKI alone. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Cui-Min Zhu Xiang-Yao Lian Hong-Yan Zhang Lu Bai Wen-Jing Yun Ru-Han Zhao Qing-Shan Li Source Type: research

Benign pathologies results from lung nodule percutaneous biopsies: How to differentiate true and false benign ?
Conclusions: Our predictive model showed good predictive ability for identifying true negatives among CTPB-based benign pathological results. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Lei Li Xiao-Liang Xu Kai Feng Xin-Qiang Liu Jing Yang Source Type: research

A nomogram to predict microvascular invasion in early hepatocellular carcinoma
Conclusion: The present study indicates that a preoperative nomogram combining PIVKA-II, AFP and tumor size could estimate the preoperative probability of MVI in early HCC patients, which may help clinicians in choosing treatment options and prognosis evaluation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Hongguang Li Tao Li Jinhua Hu Jun Liu Source Type: research

BCL6B hypermethylation predicts metastasis and poor prognosis in early-stage hepatocellular carcinoma after thermal ablation
Conclusions: BCL6B methylation could be a valuable prognostic factor for metastasis and poor prognosis in early-stage HCC after thermal ablation, which is an independent risk factor for metastasis. Our findings provide insights for combining ablation and epigenetic therapy for patients with HCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Xin Li Mingzhou Guo Lili Yang Zhigang Cheng Xiaoling Yu Zhiyu Han Fangyi Liu Qiang Sun Xianjing Han Jie Yu Ping Liang Source Type: research

Changes in thyroid antibody and T lymphocyte subsets after radiofrequency ablation of thyroid nodules in patients with autoimmune thyroiditis
Conclusions: After RFA of thyroid nodules in patients with autoimmune thyroiditis, thyroid function is not affected and no serious complications occurred. TG-Ab and TPO-Ab levels can be significantly decreased, and the distribution of T lymphocyte subsets can be changed in the short term after ablation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Xiaoyin Tang Ping Li Bo Zhai Xiaoli Zhu Source Type: research

Novel nomogram predicting cancer-specific survival and overall survival in patients with primary esophageal small-cell carcinoma: A surveillance, epidemiology, and end results-based study
Conclusions: By utilizing easily accessible clinicopathological information, we established a simple but useful tool for predicting the CSS and OS of ESmCC patients that could help to make personalized clinical decisions for patients with this rare malignancy. Cancer-specific survival, esophageal small-cell carcinoma, nomogram, overall survival, surveillance, epidemiology, and end results (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Jisheng Li Hejiang Yu Ling Peng Li Li Xiangling Wang Jing Hao Na Shao Source Type: research

The role of prostate-specific antigen and multiparametric magnetic resonance imaging in the diagnosis of granulomatous prostatitis induced by intravesical Bacillus Calmette & #8211;Gu & #233;rin vaccine therapy in patients with nonmuscle invasive bladder cancer
Conclusions: Perioperative serum PSA levels, prostate magnetic resonance imaging, and DRE may help in the diagnosis of GP induced by intravesical BCG therapy. In general, male patients with middle- and high-risk NMIBC are recommended to undertake DRE, PSA, and prostate mpMRI, if possible, before and after TURBt. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Zilong Wang Chenglin Han Yingkun Xu Xiao Yu Weiting Kang Yuzhu Xiang Yanhua Yuan Lianjun Li Muwen Wang Source Type: research

Anlotinib followed by transarterial chemoembolization and radiofrequency ablation is a safe and effective initial treatment for hepatocellular carcinoma patients with portal vein tumor thrombus: A retrospective case series study
Conclusion: Anlotinib followed by TACE and RFA is a safe and effective initial treatment modality for HCC patients with PVTT. Anlotinib may be a promising therapeutic option for relieving and/or stabilizing HCC with PVTT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Jianpeng Wang Xishan Li Fengjie Wang Degang Shi Jiren Zhang Source Type: research

Chinese expert consensus of image-guided irreversible electroporation for pancreatic cancer
Yingtian Wei, Yueyong Xiao, Zhongmin Wang, Xiaokun Hu, Guang Chen, Xiaoyi Ding, Yong Fan, Yue Han, Kaiwen Huang, Xuequan Huang, Ming Kuang, Xu Lang, Hailiang Li, Chengli Li, Jiakai Li, Jiaping Li, Maoquan Li, Yinying Lu, Caifang Ni, Lizhi Niu, Junhui Sun, Jinlin Tian, Hao Wang, Liwei Wang, Peihong Wu, Xiaoyan Xie, Wenge Xing, Linfeng Xu, Po Yang, Haipeng Yu, Chunwang Yuan, Bo Zhai, Yanfang Zhang, Jiasheng Zheng, Zhigang Zhou, Xiaoli Zhu, Tianan Jiang, Yingxun ZhangJournal of Cancer Research and Therapeutics 2021 17(3):613-618 Pancreatic cancer (PC) is a lethal disease with extremely high mortality. Although surgical resec...
Source: Journal of Cancer Research and Therapeutics - July 9, 2021 Category: Cancer & Oncology Authors: Yingtian Wei Yueyong Xiao Zhongmin Wang Xiaokun Hu Guang Chen Xiaoyi Ding Yong Fan Yue Han Kaiwen Huang Xuequan Huang Ming Kuang Xu Lang Hailiang Li Chengli Li Jiakai Li Jiaping Li Maoquan Li Yinying Lu Caifang Ni Lizhi Niu Junhui Sun Jinlin Tian Hao Wang Source Type: research

Bacillus Calmette & #8211;Gu & #233;rin-induced perinuclear antineutrophil cytoplasmic antibodies associated vasculitis in bladder cancer
Sibel Yucel Kocak, Aysegul Kudu, Suheyla ApaydınJournal of Cancer Research and Therapeutics 2021 17(2):609-612 Intravesical instillation of Bacillus Calmette–Guérin (BCG) immunotherapy remains the most effective adjuvant treatment for noninvasive bladder cancer. Systemic BCG-related complications are rare and usually related to infective agent or an immune-mediated reaction. We discussed a case with perinuclear antineutrophil cytoplasmic antibodies (p-ANCA) vasculitis, developing after instillation of BCG for non-invasive bladder cancer. A 68-year-old man presented with nephritic syndrome a few months afte...
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Sibel Yucel Kocak Aysegul Kudu Suheyla Apayd & #305;n Source Type: research

Kaposi sarcoma of the adrenal gland: A report of two cases with a review of the literature
We describe two cases of primary adrenal KS to report on this exceptional presentation of KS: the first case is a 67-year-old female with anaplastic KS wit fatal outcome. The second case is a 56-year-old male who presented a classic KS of the adrenal gland. Until now, no standard efficient treatment regimens have been clearly identified. There is a need for a further understanding of anaplastic KS's biology, and collecting a sizable patient cohort remains essential to review treatment outcome. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Sabrine Derqaoui Kaoutar Znati Zakia Bernoussi Source Type: research

A rare case of giant chromophobe renal cell carcinoma with sarcomatoid differentiation: Treatment and prognosis
Ketan Mehra, Ramanitharan Manikandan, Lalgudi Narayanan Dorairajan, Jinkala SreerekhaJournal of Cancer Research and Therapeutics 2021 17(2):602-605 Chromophobe renal cell carcinoma (RCC) with sarcomatoid differentiation is an infrequent entity. In the current era of advanced imaging techniques, RCCs are usually detected in early stages, and a localized giant tumor is rarely encountered. Recently, we encountered a patient with a localized giant RCC, which was 36 cm in the largest dimension and weighing 5.1 kg, which was resected entirely but presented relapse and succumbed within 3 months of surgery. (Source: Journal of Ca...
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Ketan Mehra Ramanitharan Manikandan Lalgudi Narayanan Dorairajan Jinkala Sreerekha Source Type: research

First case of acrometastases to the wrist reported from penile cancer
We report the first case of a patient with acrometastases to the left wrist reported from penile cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Paulina Cegla Ewelina Konstanty Magdalena Fundowicz Katarzyna Pietrasz Krzysztof Matuszewski Aleksandra Heydrych Tomasz Piotrowski Source Type: research

The prostatic adenocarcinoma with mucinous features: A review of the literature with three case reports
In this study, the treatment and surveillance processes of our three patients with prostatic adenocarcinoma with mucinous features were presented along with a literature review. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Nejdet Karsiyakali Emre Karabay Ugur Yucetas Sevim Baykal Koca Ali Ferruh Akay Mustafa Kadihasanoglu Source Type: research

A rare case of bilateral synchronous renal tumors with different histology successfully treated with bilateral partial nephrectomy
We report one such case in a 45-year-old male patient, who was successfully managed by performing bilateral partial nephrectomy in two sittings. The histopathological examination revealed different histology on each side. Both preservations of renal parenchyma and tumor eradication should be considered in bilateral synchronous sporadic RCC before formulating a therapeutic regime. Management by nephron-sparing surgery approach performed in a staged manner offers adequate cancer-specific survival while ensuring good renal function. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Shashanka Dhanuka Ankit Kayal Tapan Kumar Mandal Jyoti Dhanuka Source Type: research

Primary intratesticular rhabdomyosarcoma, a rare entity: A case report with review of literature
Pavan Kumar Lachi, N Armugham, B Triveni, B Sheela, M Rama KrishnaJournal of Cancer Research and Therapeutics 2021 17(2):590-592 Paratesticular rhabdomyosarcoma is a very rare mesenchymal tumor. It is an intrascrotal tumor that is localized in paratesticular structures such as the epididymis or spermatic cord. Rhabdomyosarcoma is most often observed in children and adolescents, presenting as a painless scrotal mass. An 18-year-old man presented with a painless left scrotal mass and lump abdomen that had evolved over four months. A histological examination of the lesion revealed rhabdomyosarcoma. Chemotherapy with alternat...
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Pavan Kumar Lachi N Armugham B Triveni B Sheela M Rama Krishna Source Type: research

A rare case report of transitional urothelial carcinoma metastasizing to isolated upper cervical lymph node diagnosed on cytology
We report here a case of a 53-year-old male who presented with Level II cervical node enlargement after 5 years of being diagnosed and treated for urothelial carcinoma. The diagnosis of cervical metastasis from urothelial carcinoma was suggested by fine-needle aspiration cytology and confirmed by immunocytochemistry. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Sumaira Qayoom Mala Sagar Divya Goel Madhu Mati Goel Source Type: research

Recurrence of renal cell carcinoma after three decades in an octogenarian: Small molecules adding life to years
We present here a case of RCC with solitary metastasis to the pleura which occurred 32 years after nephrectomy. Our patient is an 86-year-old male who presented to us with a cough of 2 months and a history of having undergone a right nephrectomy 32 years back. Imaging of the chest showed left pleural effusion with a left pleural nodule. Computed tomography-guided fine-needle aspiration cytology from the pleural nodule was suggestive of malignancy with a clear cell morphology, suggestive of clear cell RCC. The patient was started on sunitinib 25 mg once daily. After the 1st month, the patient's performance status improv...
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Arun Philip Annie Jojo Pavithran Keechilat Source Type: research

Radiation cystitis: A late effect of radiotherapy in a patient with cervical rhabdomyosarcoma
In this report, we discuss a review of management strategies for cervical rhabdomyosarcoma and also throw some light on incidence and management of radiation cystitis after pelvic radiotherapy. We discuss the dose independence of radiation cystitis, which can be seen after as low as 4500 cGy of pelvic radiation. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Rituraj Upadhyay SM Carthikeyan Sushmita Pathy Source Type: research

Neuroendocrine carcinoma of prostate presenting with ascites
Nishant Sagar, Pritika Kushwaha, Varuna Mallya, Shyama Jain, Nita Khurana, NS HadkeJournal of Cancer Research and Therapeutics 2021 17(2):577-579 Prostate cancer is a very common cause of morbidity and mortality in India. The commonest type of prostate carcinoma is adenocarcinoma, most of them are confined to prostate at the time of presentation. Bone is the preferred site for metastasis. The following is a case of neuroendocrine carcinoma of prostate arising in a 36 years old male who presented with ascitis and jaundice to the emergency department. The ascitic tap was positive for malignant cells. CECT done to detect pri...
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Nishant Sagar Pritika Kushwaha Varuna Mallya Shyama Jain Nita Khurana NS Hadke Source Type: research

Effect of COVID-19 outbreak on community screening program for cancer prevention: A note from endemic area of cholangiocarcinoma
Sora Yasri, Viroj WiwanitkitJournal of Cancer Research and Therapeutics 2021 17(2):576-576 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Sora Yasri Viroj Wiwanitkit Source Type: research

Positron emission tomography-computed tomography use during the COVID-19 pandemic outbreak
Sibel Goksel, Sema Yilmaz RakiciJournal of Cancer Research and Therapeutics 2021 17(2):574-575 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Sibel Goksel Sema Yilmaz Rakici Source Type: research

Role of glutathione S-transferase P1 polymorphism in early transplant complications in patients undergoing allogeneic stem cell transplantation
Conclusions: TSI was higher in the GSTP1 polymorphism group. GSTP1 polymorphism had no effect on early transplantation complications. Although the OS and TRM ratios were higher in the GSTP1 polymorphism group, no statistically significant difference was found between the groups. Further studies with larger sample size are needed. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Hazen Saritas Elif Suyani Sezen G & #252;ntekin Aki & #350;ahika Zeynep Mehmet Ali Erg & #252;n B & #252;lent & #199;elik G & #252;lsan T & #252;rk & #246;z Sucak Source Type: research

Clinical presentation and course of the novel coronavirus disease 2019 in patients with various types of cancer: A retrospective case & #8211;control analysis of an experienced cancer center in Turkey
Conclusion: Our practices supported that cancer patients were more affected by COVID-19 disease than the normal population. However, our findings can not be generalized due to being retrospective and single centered study, Also, we did not compare the findings with noncancer patients with COVID19 disease. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Ramazan Acar Gulden Yilmaz Umit Savasci Musa Baris Aykan Halil Kiziloz Ferhat Cuce Ekin Kadioglu Mine Filiz Gonca Fidan Sami Eksert Gurhan Taskin Deniz Dogan Yakup Arslan Cant & #252;rk Tasci Neslihan Kayahan Tolga Dogan Bilgin Bahadir Basgoz Erdim Sertog Source Type: research

Strategies to ensure efficient laboratory functioning while navigating through the COVID-19 crisis in developing countries: An early experience from a tertiary care centre in India
Conclusion: We hope this will address the concerns of small to medium sized laboratories and help them build an effective strategy required for protecting the laboratory personnel from risk of exposure and also ensure smooth and optimum functioning of the laboratory services. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Puneet Kaur Somal Sankalp Sancheti Akash Pramod Sali Saloni Bansal Supreet Kaur Kalra Anantika Thakur Neha Gupta Rakesh Kapoor Source Type: research

Impact of the COVID-19 pandemic on health care activities at a Uruguayan mastology unit
Conclusions: The evidence suggests that, although medical appointments decreased by approximately 17%, we could maintain healthcare activities, continued most of the treatments while the most modified was CT with G-CSF to avoid myelosuppression. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Cecilia Castillo Natalia Camejo Dahiana Amarillo Florencia Rodriguez Florencia Vitureira Gabriel Krygier Luc & #237;a Delgado Source Type: research

Duramycin radiosensitization of MCA-RH 7777 hepatoma cells through the elevation of reactive oxygen species
Conclusion: Duramycin increased the intracellular ROS generation and also increased the radiosensitivity of MCA-RH 7777 cells. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 11, 2021 Category: Cancer & Oncology Authors: Bowen Yang Xiaoke Huang Weiguo Li Samdeep Mouli Robert J Lewandowski Andrew Christian Larson Source Type: research