Erratum: Comparison of the short-term clinical outcome between open and minimally invasive esophagectomy by Comprehensive Complication Index
Journal of Cancer Research and Therapeutics 2019 15(2):447-447 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Source Type: research

Apatinib and S-1 combination therapy for the treatment of advanced head and neck neoplasms: Three case reports
Min Meng, Xin Ye, Xia Yang, Guanghui Huang, Zhigang Wei, Yang Ni, Wenhong Li, Xiaoying Han, Jiao WangJournal of Cancer Research and Therapeutics 2019 15(2):442-446 Apatinib, one of the novel oral antiangiogenic agents, shows survival benefits in treating advanced or metastatic gastric adenocarcinoma. However, its efficacy in treating advanced head and neck neoplasms has not been reported. Herein, three elderly men with advanced head and neck neoplasms were treated with apatinib and S-1. Their initial diagnoses were hypopharyngeal carcinoma, metastatic squamous cell carcinoma of head and neck, and squamous cell carcinoma o...
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Min Meng Xin Ye Xia Yang Guanghui Huang Zhigang Wei Yang Ni Wenhong Li Xiaoying Han Jiao Wang Source Type: research

Usefulness of large-section cytokeratin 20 in the detection of intestinal wall infiltration and mesangial metastasis in patients with middle and lower rectal cancer
Conclusion: The large-section CK20 staining technique is useful for the detection of infiltration on the distal wall and mesangial metastasis in patients with middle and lower rectal cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Ke-Shu Shan Xiao-Peng Zhang Jin-Shen Wang Xiao-Bo Guo Liang Shang Feng Tian Chang-Qing Jing Le-Ping Li De-Sen Wan Chen-Sheng Li Source Type: research

Prognostic value of the Epstein & #8211;Barr virus and tumor suppressor gene p53 gene in nasopharyngeal squamous cell carcinoma
Conclusions: We concluded that there were the correlations between NPSCC subtypes with EBV infection and frequent intaking of pickled food, while aging, clinical recurrence, and TP53 gene mutations were independent predictors for the poor prognosis of nasopharyngeal carcinoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Junjie Liu Ying Liu Zhenyu Zhang Hongwei Sun Xiaofei Ji Boqing Li Xiuzhi Zhou Pengzhou Gai Source Type: research

Expression of polymeric immunoglobulin receptor and its biological function in endometrial adenocarcinoma
Conclusion: PIgR may be a predictive biomarker of endometrial adenocarcinoma and a potential target protein for immunotherapy of endometrial adenocarcinoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Mingshu Zhou Chongdong Liu Guangming Cao Huiqiao Gao Zhenyu Zhang Source Type: research

Endoscopic ultrasonography-guided poly (lactic acid-co-glycolic acid)-poly (ethylene glycol)-poly (lactic acid-co-glycolic acid) thermogel tunnel creation for natural orifice transluminal endoscopic surgery in porcine model
Conclusion: The application of thermogel for tunnel creation in NOTES could optimize current procedures and may have a promising prospect in clinical application. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Xiaotian Sun Lin Yu Jianbin Zhu Shengzhou Zu Jiandong Ding Yan Liu Source Type: research

Local tumor control of thoracoabdominal wall seeding tumor from hepatocellular carcinoma with ultrasound-guided interventional treatment: A summarized study
Conclusions: US-guided interventional treatments were an effective option in LTC for TAWST from HCC, and MWA could achieve comparable long-time survival outcomes with SR for HCC patients with TAWST. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Chao An Xin Li Ping Liang Jie Yu Zhigang Cheng Zhiyu Han Mengjuan Mu Source Type: research

Rapamycin may inhibit murine S180 sarcoma growth by regulating the pathways associated with autophagy and cancer stem cells
Conclusion: Tumor growth delay induced by rapamycin may be associated with the suppression of the cancer stem cell phenotype (Notch1, CD133, and CD90) and promotion of autophagy (mTOR, Beclin1, ULK1, and LC3-II/LC3-I ratio) in the murine S180 sarcoma model. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Hubo Shi Lulu Zhang Chengke Zhang Yingtao Hao Xiaogang Zhao Source Type: research

Magnetic resonance imaging-guided transperineal prostate biopsy
Conclusion: MRI-guided transperineal prostate biopsy is helpful in the diagnosis and treatment of prostatic disease. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Jie Chen Zhengyu Lin Jin Chen Qingfeng Lin Jian Chen Yuan Yan Source Type: research

Efficacy and safety of a combination of hydrodissection and radiofrequency ablation therapy for benign thyroid nodules larger than 2 cm: A retrospective study
Conclusion: The combination of ultrasound-guided RFA with hydrodissection very effectively treats benign thyroid nodules while reducing damage to the surrounding tissues. This method is safe and effective for treating benign thyroid nodules. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Dan Cui Min Ding Xiaoyin Tang Jiachang Chi Yaoping Shi Tao Wang Bo Zhai Ping Li Source Type: research

Evaluation of 24-core coaxial needle saturation biopsy of the prostate by the transperineal approach in detecting prostate cancer in patients without previous biopsy history: A single-center report
Conclusions: Transperineal coaxial needle SPBx as the initial scheme improves PCa detection compared with initial systematic 14-core PBx, without increasing complications and overdiagnosis. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Fengbo Zhang Qiang Shao Yuan Du Ye Tian Source Type: research

The efficacy of endoscopic stenting combined with laparoscopy in the treatment of left colon cancer with obstruction
Conclusions: Obstructive colon cancer LR combined with SEMS insertion was a safe and feasible radical treatment strategy. The same level of procedure and effects could be achieved, compared to that of nonobstructive colon cancer LR. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Wenming Li Xin Jin Guogang Liang Source Type: research

Computed tomography-guided percutaneous cryoablation for lung ground-glass opacity: A pilot study
Conclusion: Cryoablation may serve as a safe and feasible option for the treatment of GGO. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Shupeng Liu Xinhai Zhu Zilin Qin Jiongyuan Xu Jianying Zeng Jibing Chen Lizhi Niu Meng Xu Source Type: research

Evaluation of efficacy and safety of apatinib treatment in advanced gastric cancer
Conclusion: Results indicated that apatinib was effective in heavily pretreated patients with advanced GC who experienced failure with two or more line chemotherapies. The toxicities were tolerable or could be clinically controlled. Apatinib treatment alleviated some of the clinical symptoms but did not improve QOL significantly. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Yang Yang Xiuwei Wu Fanfan Li Nianfei Wang Mingjun Zhang Tong Sun Zhendong Chen Source Type: research

Chemokine (C-C motif) ligand 18 is highly expressed in glioma tissues and promotes invasion of glioblastoma cells
Conclusion: We have found that CCL18 is highly expressed in glioma tissues and enhances the invasion, migration, and proliferation of U251 glioma cells. Therefore, CCL18 may be a potential biomarker for detecting and grading human glioma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Lixin Ma Hui Wang Zhenzhu Li Xin Geng Meng Li Source Type: research

Chromatin remodeling factor lymphoid-specific helicase links with Epstein-Barr virus associated the follicular germinal center B cell lymphomas
Conclusions: These findings indicate a critical role for LSH as a biomarker and therapeutic target in follicular germinal center B-cell lymphoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Chunhui Ouyang Zhenghao Deng Jianhua Zhou Chunyan Fu Shuang Liu Yongguang Tao Desheng Xiao Source Type: research

Clinical characteristics and prognosis of cancer patients with venous thromboembolism
Conclusions: The incidence of IPE in cancer patients was not rare. Most VTE events occurred within the first 6 months after the cancer diagnosis, and nearly half of the deaths occurred within the first 3 months of VTE diagnosis in cancer patients. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Hui Wang Xiaomao Xu Chun Pu Lin Li Source Type: research

Transauricular arterial access for hepatic artery embolization in rabbit VX2 liver tumor
Conclusion: Arterial access in rabbits can be achieved through the auricular artery. Hepatic artery catheterization, angiography, and embolization can be performed through auricular arterial access. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Bo Hu Peng Du Chao Yang Yun-Liang Wang Cai-Fang Ni Zhi Li Source Type: research

Embolization of hepatic arterioportal shunt with ethanol-soaked gelatin sponge
Conclusion: The results show that ESG can effectively reduce APS score and improve the survival rate of HCC patients. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Jing Li Xinxin Kang Leiming Guo Jincheng Xiao Jingliang Cheng Source Type: research

The effects of microRNA-1224-5p on hepatocellular carcinoma tumor endothelial cells
Conclusions: miR-1224-5p may serve as a potential tumor suppressor in HCC. Upregulation in miR-1224-5p expression may decrease proliferation, induce apoptosis, inhibit migration and invasion, and suppress tube formation in TECs of human HCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Chao Hu Xi Cheng Qi MingYu Xin Bao Wang Shi Qiang Shen Source Type: research

Chyle test is not a valuable laboratory index in identifying chylothorax after pulmonary resection and lymph node dissection for primary non-small cell lung cancer
Conclusions: It was suggested that the specificity and accuracy of chyle test in identifying chylothorax were relatively low. Chyle test is not a good laboratory index in identifying chylothorax. With highly positive result, chyle test should not preclude the removal of chest tube in patients after pulmonary resection and lymph node dissection for primary NSCLC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Hui Wang Jinping Gao Renfeng Zhang Hounai Xie Zhongmin Peng Source Type: research

Receptors for advanced glycation end products is associated with autophagy in the clear cell renal cell carcinoma
Conclusion: Our results implicated that RAGE and autophagy played important roles in ccRCC, and RAGE/HMGB1 might serve as a novel therapeutic target for future ccRCC treatment. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Yong Guo Hai-Cong Zhang Sheng Xue Jun-Hua Zheng Source Type: research

Nimotuzumab plus chemotherapy with docetaxel, cisplatin, 5-fluorouracil for locally advanced head and neck squamous cell carcinoma: A clinical study
Conclusions: Nimotuzumab in combination with TPF has been well tolerated as a treatment program for locally advanced HNSCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Xing Wang Jianmin Gu Cuiling Shao Kun Han Jian Meng Source Type: research

Transcatheter arterial chemoembolization experience for advanced hepatocellular carcinoma with right atrial tumor thrombus
Conclusion: For HCC with tumor thrombus in the IVC and RA, TACE could safely improve the prognosis of these patients. Searching for multiple feeding arteries are essential for ensuring efficacy. In addition, careful examination and appropriate embolization technique are essential for safety and efficacy. Lipiodol was a safe and ideal agent for the embolization in RATT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Linzhong Zhu Renjie Yang Xu Zhu Source Type: research

Prospective and prognostic factors for hepatic metastasis of gastric carcinoma: A retrospective analysis
Conclusions: The therapy design for patients with GCLM should consider the general conditions and personal clinicopathological characters of patients. After balancing the benefit and risk factors, multidisciplinary treatment and individual treatment should be developed based on evidence-based medicine model for each patient. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Jin Cheng Song Xiao Lei Ding Yang Zhang Xian Zhang Xiu Hua Sun Source Type: research

Precision dose measurement of 125I seed in solid water through SPECT/CT detecting
Conclusion: The count value around the 125I seed can be detected accurately by SPECT/CT, and then can be quantified. This study provided useful experiment data for the precision measurement of 125I seed implantation. Radiation detection-based dose measurement may become a new noninvasive technology for the dynamic dosimetry verification method after brachytherapy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Hongtao Zhang Yansong Liang Gang Qiu Zeyang Wang Devjoy Dev Zezhou Liu Huijuan Li Huimin Yu Jingshi Chen Aixia Sui Juan Wang Gaofeng Shi Source Type: research

Experimental study in vivo ablation of swine pancreas using high-intensity focused ultrasound
Conclusions: It was feasible and safe to use HIFU for ablation of the pancreas in swine. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Guanghui Huang Xin Ye Xia Yang Aimin Zheng Wenhong Li Jiao Wang Xiaoying Han Zhigang Wei Min Meng Yang Ni Chengkun Qin Xingbo Fei Liulin Xiong Source Type: research

Role of miRNA in transformation from normal tissue to colorectal adenoma and cancer
Guangkuo Liu, Bingqing LiJournal of Cancer Research and Therapeutics 2019 15(2):278-285 Although many modalities can be used to prolong the remission of colorectal cancer (CRC), early diagnosis is essential to improve the therapeutic outcomes. The conventional ways of diagnosing and monitoring the progresses from adenoma to CRC are colonoscopy and fecal occult blood test (FOBT). However, colonoscopy is expensive and invasive; while the FOBT is not sensitive. miRNAs may be a new modality to monitor the transition from adenoma to CRC. We reviewed publications of miRNA profile differences from colorectal normal mucosa (NM) t...
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Guangkuo Liu Bingqing Li Source Type: research

Targeting the canonical Wnt/ & #946;-catenin pathway in cancer radioresistance: Updates on the molecular mechanisms
Yu Yang, Huandi Zhou, Ge Zhang, Xiaoying XueJournal of Cancer Research and Therapeutics 2019 15(2):272-277 Radiation resistance is an important factor that affects the efficacy of radiotherapy; it could even lead to its failure. In recent years, the relationship between the classical Wnt signaling pathway and radiation resistance has gradually attracted attention from scholars. Although most of the findings are comprehensive, they are fragmented and disorganized. This review explores the relationship between classical Wnt signaling pathways and cancer radiation resistance. Previous literature regarding the classical Wnt s...
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Yu Yang Huandi Zhou Ge Zhang Xiaoying Xue Source Type: research

Translational epidemiology: The powerful tool for precision cancer medicine
Zhenming Fu, Rui Zhang, Ping Li, Mingfang JiaJournal of Cancer Research and Therapeutics 2019 15(2):269-271 Although this is an exciting time for translational medicine, systematic approaches and strategies to conduct translational research are sparse. We highlight in this editorial the opportunities to collaborate across disciplines and to forge new interdisciplinary collaborative ventures from the perspective of epidemiology. We specifically outline some feasible research areas, wherein Translational Epidemiology may readily speed up the translation of research for Precision Medicine. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Zhenming Fu Rui Zhang Ping Li Mingfang Jia Source Type: research

Programmed cell death protein-1 inhibitor for the treatment of hepatocellular carcinoma: & #8220;A sharp sword & #8221;
Xin Li, Ping Liang, Xin YeJournal of Cancer Research and Therapeutics 2019 15(2):267-268 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Xin Li Ping Liang Xin Ye Source Type: research

Computed tomography-guided percutaneous microwave ablation: A new weapon to treat ground-glass opacity & #8211;lung adenocarcinoma
Yancu Hertzanu, Xin YeJournal of Cancer Research and Therapeutics 2019 15(2):265-266 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - April 1, 2019 Category: Cancer & Oncology Authors: Yancu Hertzanu Xin Ye Source Type: research

Primary prostatic non-Hodgkin & #39;s lymphoma presenting with features of prostatism
Pradeep Kumar, Khaliqur Rahman, Nosad Hussein, Ruchi Gupta, Soniya NityanandJournal of Cancer Research and Therapeutics 2019 15(8):178-179 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Pradeep Kumar Khaliqur Rahman Nosad Hussein Ruchi Gupta Soniya Nityanand Source Type: research

Screening for prostate cancer starting at age 50 & #8211;54 years
Beuy Joob, Viroj WiwanitkitJournal of Cancer Research and Therapeutics 2019 15(8):177-177 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Beuy Joob Viroj Wiwanitkit Source Type: research

Intraosseous lipoma of the maxillary tuberosity: A rare entity with diagnostic challenge
Sharlene Sara Babu, S Sunil, Nithin Pratap, Eapen ThomasJournal of Cancer Research and Therapeutics 2019 15(8):173-176 Lipoma is called the “universal tumor” or the “ubiquitous tumor” as it occurs anywhere in the body where fat is found. Intraosseous lipoma is a rare lesion that constitutes not more than 0.1% of bone tumors. There are only a few reported cases of intraosseous lipoma of the maxilla in the literature. The diagnosis of intraosseous lipoma of the maxilla may be a challenge, due to its rarity and clinical similarity with many other radiolucent lesions. Therefore, histopathological e...
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Sharlene Sara Babu S Sunil Nithin Pratap Eapen Thomas Source Type: research

Hypercalcemia associated with squamous cell carcinoma of renal pelvis: A case and review of the literature
Fatma Yalcin Musri, Hasan Mutlu, Melek Karakurt Eryilmaz, Derya Kivrak Salim, Gokhan Tazegul, Hasan Şenol CoşkunJournal of Cancer Research and Therapeutics 2019 15(8):170-172 Renal pelvis squamous cell carcinoma (RSCC) is a rare tumor. It starts with nonspecific symptoms and it is usually at an advanced stage with a poor prognosis at the time of diagnosis. SCC-associated hypercalcemia is a well-known paraneoplastic syndrome; however RSCC-associated hypercalcemia is a rare condition. Our patient is a 57-year-old-male patient with no bone metastases. Based on the literature screening on PubMed Database for paraneo...
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Fatma Yalcin Musri Hasan Mutlu Melek Karakurt Eryilmaz Derya Kivrak Salim Gokhan Tazegul Hasan & #350;enol Co & #351;kun Source Type: research

Malignant mesothelioma of tunica vaginalis without any risk factors: An uncommon case
Chirag B Punatar, Kunal K Jadhav, Vikash Kumar, Sharad N SagadeJournal of Cancer Research and Therapeutics 2019 15(8):167-169 Malignant mesothelioma (MM) of the tunica vaginalis (TV) is a rare tumor. It is seen in elderly patients, with painless scrotal swelling being the most common presentation. The exact etiology is unknown; a few risk factors have been suggested. Here, we present an uncommon case of MM of TV without any known predisposing factors. We also discuss the possible risk factors, clinical presentation, pathological features and the difficulties in diagnosis, and management of this rare malignancy. (Source: J...
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Chirag B Punatar Kunal K Jadhav Vikash Kumar Sharad N Sagade Source Type: research

Adrenal adenoma in von Hippel & #8211;Lindau syndrome: A case report with review of literature
Rajan Palui, Sadishkumar Kamalanathan, Jayaprakash Sahoo, Lalgudi Narayanan Dorairajan, Bhawana Badhe, Debasis GochhaitJournal of Cancer Research and Therapeutics 2019 15(8):163-166 A 29-year-old hypertensive male with von Hippel–Lindau (VHL) syndrome came to the Endocrinology department for evaluation. Contrast-enhanced computed tomography of the abdomen revealed an adrenal mass, bilateral renal cell carcinoma, and multiple pancreatic cysts. The hormonal investigations for adrenal mass were normal. He underwent left-sided adrenalectomy, and the histopathological report was suggestive of an adrenocortical adenoma. G...
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Rajan Palui Sadishkumar Kamalanathan Jayaprakash Sahoo Lalgudi Narayanan Dorairajan Bhawana Badhe Debasis Gochhait Source Type: research

Staging a great escape -Incidentally detected renal urothelial carcinoma with extensive squamous metaplasia presenting as pyonephrosis
We report the case of a 70-year-old female patient who presented with flank pain, pyuria, fever, and a unilateral nonfunctioning kidney with nephrolithiasis and pyonephrosis on pyelography. Routine imaging failed to identify a mass lesion. In an Indian setting, the clinical differential of tuberculosis was considered likely. A nephrectomy was performed in view of the poor perfusion and functional status of the right kidney. Histopathological examination of the kidney showed a tumor of urothelial origin arising at the renal pelvis displaying extensive squamous metaplasia. Such a near total metaplastic change is rare and has...
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Kavita Gaur Latika Gupta Ravindra Kumar Saran Deepak Ghuliani Source Type: research

Integrating systemic module inference with attract method excavates attractor modules for cyclophosphamide contributing to prostate cancer
Conclusions: We predicted that during the process of chemotherapy, CPA mainly affected the pathways of DNA replication and nucleotide excision repair to induce the cancer cell's death. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Guodong Sun Wenjing Zhang Jing Wang Source Type: research

Evaluation of effects of morphine and ionizing radiation in cancer cell lines
Conclusions: Our data may suggest that morphine and radiotherapy could not be administered together to breast and cervical cancer patients if additional and in vivo studies confirm our results. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Jamal Naderi Fariba Samani Alireza Amooheidari Shaghayegh Haghjooy Javanmard Gelareh Vahabzadeh Golnaz Vaseghi Source Type: research

An analytical study of effect of the cell proliferation, half-life, and energy of radionuclides in targeted radiotherapy
Conclusion: Due to high dose-rate, the shorter decay half-life is more effective in comparison to longer ones. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Hassan Ranjbar Source Type: research

Expression of transforming growth factor-beta and interferon gamma biomarkers after whole body gamma irradiation
Conclusions: The results of this study showed the changes in the expression of TGF-β and IFN-γ genes after irradiation more than 100 mGy in lymphocytes compared to the control group; the changes in the serum levels of these cytokines only occurred in the specific doses compared to the control group. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Reza Fardid Parisa Ghahramani Mohammad-Amin Mosleh-Shirazi Tahereh Kalantari Abbas Behzad-Behbahani Elaheh Kazemi Mohammad-Ali Okhovat Source Type: research

A Monte Carlo evaluation of dose distribution of commercial treatment planning systems in heterogeneous media
Conclusion: Significant differences were found when the calculation algorithms were compared with MC method in lung tissue, and this difference is not negligible. It is recommended to use of MC-based TPS for the treatment fields including lung tissue. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Mohsen Hasani Kheirollah Mohammadi Mahdi Ghorbani Soraya Gholami Courtney Knaup Source Type: research

Comparison of thermoluminescent dosimeter calibration irradiated in gamma knife and 60Co instruments
Conclusions: The result showed despite differences in calibration conditions, 60Co unit can be used to calibrate TLD dosimeter for estimating the accuracy of measurement of delivered dose to organs of patients undergoing Gamma Knife 4C radiosurgery treatment. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Mohadese Moafi Ghazale Geraily Ali Reza Shirazi Source Type: research

Dosimetric evaluation of electron total skin irradiation using gafchromic film and thermoluminescent dosimetry
Conclusion: Based on the results of this study, stationary techniques are preferred for TSEBT. The main advantage of rotational techniques is reducing the time of treatment. The results also demonstrate that TLD should be routinely used in TSEBT treatment. Due to the high sensitivity of radiochromic films, this type of film was suitable for a wide therapeutic field. Comprehensive treatment to Rando phantom showed that the uniformity is better at the trunk than in the mobile parts of the body; the soles of the feet, perineum region, and scalp vertex should be treated in boost. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Leila Falahati Hassan Ali Nedaie Mahbod Esfahani Nooshin Banaee Source Type: research

Effect of scattering and differential attenuation on beam profile in the presence of high-density intensity modifying compensator
Conclusions: The presence of compensator changes photon beam mean energy along the cross-section resulted in decreased beam flatness and increased scattering. This may lead to overestimation of dose along off-axis within radiation field if change in flatness is not taken into account and more exposure to healthy tissues in penumbral region due to large-angle scattering. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Sandeep Kaushik Rajesh Punia Atul Tyagi Anand Malik Source Type: research

Measurement of fast neutron contamination caused by the presence of wedge and block using CR-39 detector
Conclusion: The presence of a wedge in a therapeutic high-energy photon field is a source of neutron contamination and may be of concern regarding clinical aspects. The results of this study show that superficial tissues such as skin will incur higher fast neutron contamination than the deep tissues. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Benyamin Khajetash Mohammad Taghi Bahreyni Toossi Mahdi Ghorbani Mehdi Jahangiri Fateme Akbari Source Type: research

Water equivalent radiological properties of Gafchromic external beam therapy and external beam therapy 2 film dosimeters
Conclusion: Presence of high atomic number element chlorine, potassium, and bromine may disturb the water equivalent properties in the lower energy range <100 KeV and similarly enhance the dose sensitivity because of the strong photoelectric absorption process. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: K Srinivasan E James Jabaseelan Samuel Source Type: research

Risk factors of renal cell carcinoma in a cohort of Sri Lankan patients: A case & #8211;control study
Conclusions: Average age at the time of diagnosis of RCC in Sri Lankan patients is lower than the developed world, with a large proportion of patients being under 50 years. Obesity, hypertension, and DM are associated risk factors for RCC in Sri Lankan patients while smoking is not. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - March 22, 2019 Category: Cancer & Oncology Authors: Balasingam Balagobi Kalhar Indika W.Muditha C.K. Samaraweera K.Suranga N Wijayarathna Hansika P Maddumage Kugadas Sutharshan Swarna Suvendran Anuruddha M Abeygunasekera Source Type: research