Clinical characteristics of Poland & #39;s syndrome associated with breast cancer: Two case reports and a literature review
Yan Huang, Hanmin Pang, Shujuan Jin, Xiaowei Han, Xiaojing Liu, Liuchun Yang, Si Zuo, Jianpeng Li, Di MengJournal of Cancer Research and Therapeutics 2018 14(7):1665-1669 Poland's syndrome is a rare congenital malformation that is characterized by a congenital defect of the pectoralis major. It is associated with various ipsilateral upper extremity anomalies and homolateral breast hypoplasia. There have been reports of Poland's syndrome being associated with different malignancies. Here, we report two cases of Poland's syndrome associated with breast cancer (BC) and review the literature. To date, 21 cases (in...
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yan Huang Hanmin Pang Shujuan Jin Xiaowei Han Xiaojing Liu Liuchun Yang Si Zuo Jianpeng Li Di Meng Source Type: research

125I seeds implantation for an elderly patient of skin squamous cell carcinomas with ulcer guided by ultrasound
Yansong Liang, Xuemin Di, Zezhou Liu, Jinxin Zhao, Zeyang Wang, Jing Zhao, Aixia Sui, Hongtao Zhang, Juan WangJournal of Cancer Research and Therapeutics 2018 14(7):1660-1664 The skin squamous cell carcinoma (SCC) is a kind of malignancy of keratinocytes. SCC was originated within the epidermis or relevant appendages, which commonly occurred on sunlight exposure sites, such as the head and neck. This case report described an 85-year-old female patient with skin SCC at the right frontal, accompanied with skin ulcer. This patient suffered from indications that were not suitable for surgical resection, including old age, Alz...
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yansong Liang Xuemin Di Zezhou Liu Jinxin Zhao Zeyang Wang Jing Zhao Aixia Sui Hongtao Zhang Juan Wang Source Type: research

Expression of leukocyte immunoglobulin-like receptor B2 in hepatocellular carcinoma and its clinical significance
Conclusion: LILRB2 might play an important role in HCC progression and correlate with poor prognosis of HCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xinwen Li Xiaojuan Wei Huirong Xu Zuowei Sha Aiqin Gao Yuping Sun Juan Li Liyou Xu Source Type: research

Cerebral air embolism during percutaneous computed tomography scan-guided liver biopsy
Conclusions: Clinicians should focus on timely and correct diagnosis of this complication during their interventional procedures. The current main treatment for this complication has been hyperbaric oxygen therapy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Dengjun Sun Ping Sui Weiwei Zhang Liangming Zhang Hao Xu Source Type: research

Personalized discovery of disrupted pathways and significant genes in preeclampsia based on accumulated normal tissue data
Conclusion: The iPAS method is suitable for identifying disrupted pathways in PE. Pathway of formation of tubulin folding intermediates by CCT/TriC might play important roles in PE. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Ying Luo Xiao-Chen Ma Qing Gao Lu-Quan Cao Source Type: research

Probing pathway-related modules in invasive squamous cervical cancer based on topological centrality of network strategy
Conclusions: The bioinformatics elucidation of certain pathway-related modules and hub genes might be beneficial to understand the molecular pathogenesis and reveal their potential as novel molecular markers of SCC to a great extent. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xiu-Hua Fu Yu-Fang Wu Fang Xue Source Type: research

Clinical application of planar puncture template-assisted computed tomography-guided percutaneous biopsy for small pulmonary nodules
Conclusions: PPT-assisted lung biopsy technology can provide high success rate and low complication incidence. It would be helpful to make the puncture procedures more standard for better clinical applications. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Zhe Ji Guan Wang Baoming Chen Yuwei Zhang Li Zhang Fuchun Gao Shude Chai Bin Huo Guangjun Zheng Xiaodong Huo Baoming Wang Xudong Zhu Dan Meng Lejun Liu Rui Zhu Mingyong Han Ying Zhang Kaixian Zhang Junjie Wang Source Type: research

Favorable progression-free survival in women with two different histopathological subtypes of bilateral breast cancer
Conclusions: In comparison to S-his, D-his BBC patients had longer PFS, which was associated with lower levels of Ki67 and a decreased lymph node metastasis rate. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yuyi Wang Chi Du Li Tu Feng Luo Xi Yan Source Type: research

Folate-receptor-positive circulating tumor cells as an efficacious biomarker for the diagnosis of small pulmonary nodules
Conclusion: FR+CTC is a reliable biomarker for the early diagnosis of small-sized lung cancer. Further study with larger sample size is required to assess the diagnostic efficiency of FR+CTC in patients with large nodule sizes. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yang Xue Wei Cong Shenglong Xie Jun Shu Gang Feng Hong Gao Source Type: research

Induction chronomodulated chemotherapy plus radiotherapy for nasopharyngeal carcinoma: A Phase II prospective randomized study
Conclusion: Compared with conventional chemotherapy, induction chrono-chemotherapy seemed to reduce chemotherapy-related toxicities and improve average local relapse time in patients treated with combined chemoradiotherapy for NPC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xiao-Xia Gou Feng Jin Wei-Li Wu Jin-Hua Long Yuan-Yuan Li Xiu-Yun Gong Guo-Yan Chen Xiao-Xiao Chen Li-Na Liu Source Type: research

Transurethral endoscopic submucosal en bloc dissection for nonmuscle invasive bladder cancer: A comparison study of HybridKnife-assisted versus conventional dissection technique
Conclusions: The application of the HybridKnife lead to a decrease in complications and RFS rate, which was a more safe and effective approach for NMIBC than conventional TURBT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yong-yi Cheng Yi Sun Jing Li Liang Liang Tie-jun Zou Wei-xing Qu Ya-zhuo Jiang Wei Ren Chun Du Shuang-kuan Du Wen-cai Zhao Source Type: research

Comparison of treatment efficacy between adjuvant intravenous chemotherapy and intravenous chemotherapy combined with intraperitoneal perfusion chemotherapy to treat postresection colon cancer
Conclusion: After radical resection, patients who received IVC + IPC showed prolonged DFS than those received IVC, as well as fewer peritoneal metastasis. Compared to IPC, no significantly increased side effects or complications were occurred after IVC + IPC. More work should be performed to confirm that IVC + IPC was superior to IVC for treating postresection colon cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Tao Jiang Rui Feng Zhangchi Pan Qian Xu Wenyu Gao Sheng Yang Qiang Chen Source Type: research

Standardized nursing and therapeutic effect of oxycontin on oral mucosal pain in nasopharyngeal carcinoma patients
Conclusion: Patients with NPC having oral mucosal pain after radiotherapy and chemotherapy need intervention at the earliest. The application of OxyContin and cancer pain standardized nursing care can improve the analgesic efficacy, reduce drug adverse effects, and improve the patient's quality of life. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Wen Hu Linmin Chen Cong Wang Ling Guo Xin Hua Yucong Cai Yuying Fan Source Type: research

Prolonged overall survival in metastatic gastric cancer treated with ipilimumab and lapatinib
Conclusion: Targeted therapy combined with immunotherapy might be a useful option for metastatic gastric. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yanfang Ju Shengjie Sun Shunchang Jiao Source Type: research

Effect of preintravenous injection of parecoxib, combined with transversus abdominis plane block in strategy of enhanced recovery after radical resection of colorectal cancer
Conclusion: The combination of parecoxib, TAP, and PCIA pump could significantly reduce patient postoperative pain and enhance recovery. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Jiangbo Zheng Zhaoming Feng Junfeng Zhu Source Type: research

Diagnosis and treatment of hemangiopericytoma in the central nervous system
Conclusion: The diagnosis of HPC depends on the pathology. Currently, the surgery and postoperative radiotherapy provide a good treatment results, while the wholeness of surgical resection is of particular importance. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Fang Liu Boning Cai Yu Du Yurong Huang Source Type: research

Serum miR-20a and miR-486 are potential biomarkers for discriminating colorectal neoplasia: A pilot study
Conclusion: The results suggested that serum miR-20a and miR-486 could be potential noninvasive biomarkers for identifying CRN patients. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Qinglan Yang Shuiming Wang Jianfeng Huang Chengwan Xia Heiying Jin Yimei Fan Source Type: research

The clinical significance of ultrasound grayscale ratio in differentiating markedly hypoechoic and anechoic minimal thyroid nodules
Conclusions: USGRs could objectively quantize grayscale values of markedly hypoechoic and anechoic lesions, enabling accurate and quantitative determination of nodular properties. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Zhi-Kai Lei Ming-Kui Li Ding-Cun Luo Zhi-Jiang Han Source Type: research

Safety and efficacy of transarterial interventional therapy for treatment of hepatocellular carcinoma with peritoneal metastases
Conclusions: Transarterial interventional therapy can be performed safely and may improve the prognosis of HCC patients with peritoneal metastases. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Feng Duan Yanhua Bai Li Cui Xiaohui Li Jieyu Yan Source Type: research

Liver computed tomographic perfusion for monitoring the early therapeutic response to sorafenib in advanced hepatocellular carcinoma patients
Conclusions: CTP might be applied to evaluate therapeutic effects of sorafenib in advanced HCC, where HAF could potentially serve as imaging biomarkers for monitoring early therapeutic effects after treatment. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xiaojun Shen Dong Wu Min Tang Huichuan Sun Yuan Ji Cheng Huang Mengsu Zeng Source Type: research

The safety and efficacy of interstitial 125I seed implantation brachytherapy for metastatic epidural spinal cord compression
Conclusion: Interstitial 125I seed implantation brachytherapy may be a promising local therapy, which was an alternative and palliative way for treating MESCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Jian Lu Wei Huang Zhongmin Wang Ju Gong Xiaoyi Ding Zhijin Chen Ning Xia Nannan Yang Zhiyuan Wu Chen Wang Jun Chen Source Type: research

Selenocystine inhibits JEG-3 cell growth in vitro and in vivo by triggering oxidative damage-mediated S-phase arrest and apoptosis
Conclusions: Our findings supported that human choriocarcinoma growth could be inhibited by SeC in vitro and in vivo through triggering oxidative damage-mediated S-phase arrest and apoptosis. Thus, SeC may be promising in the treatment of human choriocarcinoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Ming Zhao Yajun Hou Xiaoting Fu Dawei Li Jingyi Sun Xiaoyan Fu Zhigang Wei Source Type: research

Ligation of thoracic duct during thoracoscopic esophagectomy can lead to decrease of T lymphocyte
Conclusion: Ligation of thoracic duct during esophagectomy could lead to decreased percentage of T lymphocyte and CD4+ Tlymphocyte, especially after arch of azygos vein had been transected. The thoracic duct should be selectively ligated during esophagectomy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Rui-Feng Yang Ting-Ting Liu Peng Wang Run-Qi Zhang Chao Li Bo Han Xue-Xin Gao Lei Zhang Zhong-Min Jiang Source Type: research

Expression profile analysis identifies a two-gene signature for prediction of head and neck squamous cell carcinoma patient survival
Conclusions: The study has identified a set of novel genes and pathways that play significant roles in the carcinogenesis and progression of HNSCC. This two-gene signature may prove to be a useful therapeutic target for HNSCC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xue Xu Mengzhi Li Jun Hu Zheng Chen Jinyu Yu Yan Dong Chengtao Sun Junqing Han Source Type: research

Downregulation of basic fibroblast growth factor increases cisplatin sensitivity in A549 non-small cell lung cancer cells
Conclusion: bFGF decreased NSCLC sensitivity to cisplatin in vitro, while it enhanced colony formation ability and increased OCT-4 expression of A549 cells, which might account for its involved mechanisms of cisplatin resistance. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Long He Yousheng Meng Zhihui Zhang Yanguo Liu Xiuwen Wang Source Type: research

Metastases to the thyroid gland: A retrospective analysis of 21 patients
Conclusion: The prognosis of STMs basically depends on the anatomic sites and histological types of primary cancers, and thyroidectomy may be considered for patients with isolated metastases. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xiaowei Wang Yuan Huang Zengguang Zheng Wenming Cao Bo Chen Xiaojia Wang Source Type: research

Application value of coaxial biopsy system in needle cutting biopsy for focal ground glass-like density nodule
Conclusion: CT-guided needle aspiration biopsy yields higher diagnostic accuracy and similar postoperative complications compared with the conventional histological diagnosis. For those undiagnosed by conventional CT scan and nontolerable of surgery, CT-guided needle aspiration biopsy serves as a safe and effective intervention. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Hualong Yu Chuanyu Zhang Shihe Liu Gang Jiang Shaoke Li Liang Zhang Enhao Kang Bingping Zhang Wenjian Xu Source Type: research

Multifactorial analysis of biliary infection after percutaneous transhepatic biliary drainage treatment of malignant biliary obstruction
Conclusions: The risk factors of biliary infection after PTBD included: age, site of obstruction, drainage style, tumor stage, hemoglobin, Child–Pugh score, phenotype of peripheral blood monocyte (Treg), and results of bile culture. It was further concluded that drainage style, Child–Pugh score, and results of bile culture were independent risk factors. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Haipeng Yu Sun Yuanyuan Zhi Guo Wenge Xing Tongguo Si Xiuying Guo Fang Liu Source Type: research

Role of dexmedetomidine in reducing the incidence of postoperative cognitive dysfunction caused by sevoflurane inhalation anesthesia in elderly patients with esophageal carcinoma
Conclusion: The POCD incidence was higher in elderly patients receiving sevoflurane anesthesia and DEX could alleviate POCD in these patients through decreasing plasma TNF-α and IL-6 concentrations. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: He Zhang Zuoli Wu Xin Zhao Yong Qiao Source Type: research

Quality of life after I-125 seed implantation using computed tomography and three-dimensional-printed template guidance in patients with advanced malignant tumor
Conclusion: The results suggested that the quality of life could be improved with I-125 seed implantation using a 3D-printed individualized template under CT guidance in patients with the advanced malignant tumor. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Panfeng Wang Li Qiong Shen Heli Zhang Muyi Zhang Zhe Ji Yuliang Jiang Baohua Li Source Type: research

Treatment of high-grade gliomas using escalating doses of hypofractionated simultaneous integrated boost-intensity-modulated radiation therapy in combination with temozolomide: A modified Phase I clinical trial
Conclusions: It showed that the treatment of high-grade gliomas with hypofractionated SIB-IMRT combined with TMZ had an MTD of 3.6 Gy/f (72 Gy/20f). In addition, the results preliminarily showed improved survival. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Xiaohui Ge Xiaoying Xue Huizhi Liu Yanqiang Wang Zhiqing Xiao Lei Tian Xiaojing Chang Qiang Lin Jinming Yu Source Type: research

Combined effect of 125I and gemcitabine on PANC-1 cells: Cellular apoptosis and cell cycle arrest
Conclusion: The combined treatment of 125I and GEM-induced stronger anti-proliferation effect than single-treatment, due to the cell cycle arrest and more cellular apoptosis in PANC-1 cells. The increased Bax/Bcl-2 ratio may lead to enhanced apoptosis. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Dong Li Yun-Ming Jia Pi-Kun Cao Wei Wang Bin Liu Yu-Liang Li Source Type: research

Therapeutic approaches targeting cancer stem cells
Yunzhi Pan, Sai Ma, Kaiyue Cao, Sufang Zhou, Aiqin Zhao, Ming Li, Feng Qian, Chuanwu ZhuJournal of Cancer Research and Therapeutics 2018 14(7):1469-1475 Increasing studies have demonstrated that most tumors consisted a subpopulation of cells with stem cell properties, known as cancer stem cells (CSCs). Accumulating evidence indicated that CSCs may be critical driving force for several types of cancer. Hence, it was necessary to develop therapeutic approaches specifically targeting CSCs. In this review, first, the biological properties of CSCs were introduced, including the self-renewal and differentiation, high tumorigene...
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yunzhi Pan Sai Ma Kaiyue Cao Sufang Zhou Aiqin Zhao Ming Li Feng Qian Chuanwu Zhu Source Type: research

Chinese association of ultrasound in medicine and engineering, superficial organs and peripheral vessels committee expert consensus on clinical frequently asked questions in breast ultrasonography, June 2018
Tian'an Jiang, Yuxin Jiang, Wen Chen, Baoming Luo, Yulan Peng, Zhili Wang, Jinfeng Xu, Jianqiao Zhou, Qi Zhou, Lingyun Bao, Li Chen, Lin Chen, Qin Chen, Shuzhen Cong, Kefei Cui, Xinwu Cui, Qinmao Fang, Fengsheng Li, Huiwen Li, Jing Li, Jianchu Li, Junlai Li, Quanshui Li, Tianliang Li, Tao Li, Yanjiang Li, Zhengyi Li, Jia Liu, Yong Liu, Jun Luo, Buyun Ma, Zhe Ma, Fang Nie, Chengzhong Peng, Xiufang Sui, Hongguang Sun, Hongqiao Wang, Jing Wang, Yan Wang, Changjun Wu, Ying Xiao, Huahua Xiong, Dong Xu, Ensheng Xue, Lifang Xue, Songli Yan, Lichun Yang, Qiang Yong, Weiwei Zhan, Sheng Zhang, Xuezhen Zhang, Jianxing Zhang, Xian...
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Tian & #39;an Jiang Yuxin Jiang Wen Chen Baoming Luo Yulan Peng Zhili Wang Jinfeng Xu Jianqiao Zhou Qi Zhou Lingyun Bao Li Chen Lin Chen Qin Chen Shuzhen Cong Kefei Cui Xinwu Cui Qinmao Fang Fengsheng Li Huiwen Li Jing Li Jianchu Li Junlai Li Quanshui Li Source Type: research

Chinese expert consensus on radioactive 125I seeds interstitial implantation brachytherapy for pancreatic cancer
Baodong Gai, Fujun ZhangJournal of Cancer Research and Therapeutics 2018 14(7):1455-1462 Pancreatic cancer, also known as exocrine pancreatic carcinoma or pancreatic ductal adenocarcinoma, is one of the most challenging tumor entities worldwide, which is characterized as a highly aggressive disease with dismal overall prognosis. Treatment options for patients with locally advanced pancreatic cancer include surgery, chemotherapy, and radiotherapy. In many cases, surgical resection is not possible due to the advanced stage at diagnosis and poor responses to current treatments, therefore, treatment alternatives have to be pe...
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Baodong Gai Fujun Zhang Source Type: research

A valuable guideline of radioactive 125I seeds interstitial implantation brachytherapy for pancreatic cancer
Yancu Hertzanu, Xin YeJournal of Cancer Research and Therapeutics 2018 14(7):1453-1454 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 19, 2018 Category: Cancer & Oncology Authors: Yancu Hertzanu Xin Ye Source Type: research

Two subsequent metachronous diseases: Granuloma annulare and colon adenocarcinoma
Hatice Ataş, Fatma Aksoy Khurami, Müzeyyen Gönül, Murat AlperJournal of Cancer Research and Therapeutics 2018 14(12):1247-1248 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Hatice Ata & #351; Fatma Aksoy Khurami M & #252;zeyyen G & #246;n & #252;l Murat Alper Source Type: research

Severe hypercalcemia: A rare and unusual presentation of acute lymphoblastic leukemia
Swaminathan Dhivyasree, Jeevarathnam Dhivyalakshmi, Shuba Sankaranarayanan, Julius Xavier ScottJournal of Cancer Research and Therapeutics 2018 14(12):1244-1246 Hypercalcemia is a rare and unusual complication of childhood malignancies. Acute lymphoblastic leukemia (ALL) presenting with hypercalcemia and lytic bone lesions is very rare in children. Here, we report a case of a 4-year-old girl with ALL who presented with severe hypercalcemia and radiological evidence of osteolytic lesions. Malignancies are the most common parathyroid hormone-independent cause of hypercalcemia. Severe hypercalcemia is a life-threatening emer...
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Swaminathan Dhivyasree Jeevarathnam Dhivyalakshmi Shuba Sankaranarayanan Julius Xavier Scott Source Type: research

Paratesticular rhabdomyosarcoma mimicking complicated epididymal cyst
We report a 16-year-old boy with a paratesticular RMS mimicking epididymal cyst. To our knowledge, this is the first case reported in the literature presenting as an epididymal cyst. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Mete Kilciler Mustafa Kadihasanoglu Ozcan Atahan Source Type: research

Ultrasonographic diagnosis of benign masseter muscle hypertrophy: A case report
This article reports two cases of bilateral masseter hypertrophy having characteristic diagnostic features, along with specialized imaging modalities and review of literature. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Vihag Vinod Naphade Sameer G Kedia Pallavi Patil Siddhant Khare Source Type: research

Treatment strategy for huge hepatocellular carcinoma with intrahepatic metastasis and macrovascular invasion: a case report and literature review
Chuanchao He, Zhenyu Zhou, Zhiyu Xiao, Jie WangJournal of Cancer Research and Therapeutics 2018 14(12):1233-1236 Macrovascular invasion, such as tumor thrombus in the major portal vein (mPVTT) or major hepatic vein (mHVTT), is regarded as indicative of an advanced stage of hepatocellular carcinoma (HCC). To date, no effective treatment has been established for this kind of HCC. We herein present a case of huge HCC with intrahepatic metastasis, mPVTT, and mHVTT. The patient was successfully treated with surgical resection-based multidisciplinary treatment. The clinical presentation, treatment strategy, and outcome of this ...
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Chuanchao He Zhenyu Zhou Zhiyu Xiao Jie Wang Source Type: research

Gastric metastasis of recurrent hepatocellular carcinoma: A case report and literature review
Long Peng, Kehan Yu, Yong Li, Weidong XiaoJournal of Cancer Research and Therapeutics 2018 14(12):1230-1232 Hepatocellular carcinoma (HCC) with gastric metastasis is seldom reported. It is extremely easy to misdiagnose for primary gastric cancer with liver metastasis, especially gastric hepatoid adenocarcinoma. Here, we report a case of recurrent HCC with gastric metastasis in a 22-year-old man. He had a history of left side hepatic tumor local resection due to ruptured HCC 10 years ago. Computed tomography revealed tumors in the right liver and stomach. Endoscopy identified a massive protrusion-like malignant stromal tum...
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Long Peng Kehan Yu Yong Li Weidong Xiao Source Type: research

Fatal interstitial lung disease associated with AZD9291
Sheng-ming Deng, Jian-an Huang, Yan-bin ChenJournal of Cancer Research and Therapeutics 2018 14(12):1227-1229 AZD9291 is one of epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) for non-small cell lung cancer (NSCLC). Interstitial lung disease (ILD) induced by AZD9291 is very seldom. We provide a case of NSCLC treated with AZD9291 who developed ILD and died in order to improve the knowledge on AZD9291. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Sheng-ming Deng Jian-an Huang Yan-bin Chen Source Type: research

Symptomatic treatment of brain metastases in renal cell carcinoma with sorafenib
Dongyan Hu, Yu Hu, Jisheng Li, Xiuwen WangJournal of Cancer Research and Therapeutics 2018 14(12):1223-1226 Brain metastasis is synchronous to the diagnosis of renal cell carcinoma (RCC). The prognosis of brain metastasis in RCC with the current treatment options is dismissal. Therefore, we present a case of an elderly female patient with RCC showing a partial response of brain metastasis after 18 months of 600 mg once daily sorafenib treatment who underwent right-sided nephrectomy. Further, withdrawal of sorafenib resulted in psychiatric changes along with increased metastasis lesions, which were recovered upon resuming ...
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Dongyan Hu Yu Hu Jisheng Li Xiuwen Wang Source Type: research

Multiple intercostal neurilemmomas in a Chinese woman
Wen-Kui Sun, Wen Yang, Chen-Hui Ma, Xin-Wu Xiao, Yi Shi, Yong SongJournal of Cancer Research and Therapeutics 2018 14(12):1220-1222 Neurilemmomas are rare tumors of neural crest cell origin that occur most commonly in the head and neck region. Intercostal neurilemmomas are extremely rare and are mostly seen as solitary tumors in the posterior mediastinum. Only one case report of multiple intercostal neurilemmomas has been documented previously. In this article, we report a case of multiple intercostal neurilemmomas in a 54-year-old woman who had initially presented with progressive dull left chest pain over a 1-year perio...
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Wen-Kui Sun Wen Yang Chen-Hui Ma Xin-Wu Xiao Yi Shi Yong Song Source Type: research

Malignant solitary fibrous tumor of the kidney with liver metastasis: A case report and literature review
We report a case of SFT with liver metastasis in an adult female and discuss the pathological features as it appears in our case. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Ning Zhang Dongxiao Zhou Kai Chen Hongyan Zhang Bingcang Huang Source Type: research

Cutaneous metastasis in prostate cancer: Two cases with similar clinical findings
Ayşe Kavak, Murat Yılmaz, Haydar Kamil Çam, Volkan Tuğcu, Hülya Albayrak, Damlanur Sakız, Ümran YıldırımJournal of Cancer Research and Therapeutics 2018 14(12):1213-1216 Cutaneous metastasis of prostate cancer is rare. Lesions in this type of skin metastasis are usually seen as suprapubic nodules. Here, we presented two cases with skin metastases of prostate cancer characterized by grouped cutaneous and subcutaneous nodules. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Ay & #351;e Kavak Murat Y & #305;lmaz Haydar Kamil & #199;am Volkan Tu & #287;cu H & #252;lya Albayrak Damlanur Sak & #305;z & #220;mran Y & #305;ld & #305;r & #305;m Source Type: research

Uterine tumors resembling ovarian sex-cord tumor: A case report and literature review
This article is to summarize clinical and pathological features, diagnosis and differential diagnosis, treatment, and prognosis of UTROSCT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Li-li Fan Yang Shen Kenneth Chanda Mu-Lan Ren Source Type: research

The prognostic role of thyroid transcription factor-1 in lung adenocarcinoma
Conclusions: This study suggests that TTF-1 is not a favorable prognostic factor in lung adenocarcinoma patients. The prognostic role of CK7 and relationship between TFF-1 expression in lung adenocarcinoma and predictive role of TTF-1 expression for the selection of first-line treatment in Stage IV lung adenocarcinoma should be validated in prospective and randomized studies. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Esin Oktay Utku Oflazoglu Yelda Varol Ozgur Tanriverdi Necla Mermur Hayri Ustun Arda Lutfiye Demir Ozge Keskin Tural Ahmadli Isil Somali Ilhan Oztop Nezih Meydan Source Type: research

Combinatorial effect of curcumin and tumor necrosis factor- & #945;-related apoptosis-inducing ligand (TRAIL) in induction of apoptosis via inhibition of nuclear factor kappa activity and enhancement of caspase-3 activity in chronic myeloid cells: An In-vitro study
Conclusion: Our results conclude that curcumin and TRAIL effectively induce the apoptosis through the inhibition of NFkB activity and by enhancing the caspase-3 activity. Thus, curcumin may prove as a potent inhibitor of NFkB by representing its role in cancer pathogenesis, especially in chronic myeloid leukemia cells. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - December 11, 2018 Category: Cancer & Oncology Authors: Bushra Iqbal Archna Ghildiyal Shraddha Singh Sahabjada Siddiqui Pratibha Kumari M Arshad AA Mahdi Source Type: research