Retraction: Predictive value of excision repair cross-complementation group 1 protein in locoregionally advanced nasopharyngeal carcinomas receiving cisplatin-based concurrent chemoradiotherapy
Journal of Cancer Research and Therapeutics 2018 14(3):724-724 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Source Type: research

Hepatic metastasectomy and paclitaxel provide long-term survival for a young woman with recurrent triple-negative metastatic breast cancer: 16 years follow-up
Victor C KokJournal of Cancer Research and Therapeutics 2018 14(3):722-723 (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Victor C Kok Source Type: research

Chondrosarcoma third metacarpal: Diagnosis and management options
Vipin Sharma, Lucky Verma, Bal Chander, Seema SharmaJournal of Cancer Research and Therapeutics 2018 14(3):719-721 Chondrosarcoma is a rare malignant tumor of cartilage commonly arising in the pelvis, proximal femur, and humerus, but quite uncommon in the small bones of the hand. Although limited surgical procedures such as curettage are mentioned as a management option in low-grade chondrosarcomas, they tend to have a high rate of recurrences. Hence, wide excision is recommended as a treatment option even in low-grade chondrosarcomas of the hand. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Vipin Sharma Lucky Verma Bal Chander Seema Sharma Source Type: research

Multiple subcutaneous metastases as the solitary presenting site of colorectal cancer
We present the case of an 18-year-old male with diffuse subcutaneous metastases as a presenting feature and as the only site of distant metastases due to rectosigmoid adenocarcinoma. They clinically mimic benign skin lesions and the patient might not present to an oncologist. The diagnosis has to be established by skin biopsy, which will show tumor cell infiltration of the epidermis, dermis, and/or subcutaneous fat. There is no established local treatment for diffuse lesions. Systemic chemotherapy indicated for metastatic colon carcinoma was employed with not much favorable response. Irinotecan based chemotherapy also resu...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Chandran Nallathambi Indibor Yengkhom Singh Zuchamo Patton Source Type: research

Intraosseous neurofibroma in a 13-year-old male patient: A case report with review of literature
This article presents a case report of neurofibroma on the posterior right side of the mandible of a 13-year-old boy who is the youngest patient in the series along with a review of literature. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Asif Iqbal Sandhya Tamgadge Avinash Tamgadge Mayura Chande Source Type: research

Sinonasal malignant melanoma with metastasis: Immunohistochemistry meeting the diagnostic challenge
Prajwala Gupta, Minakshi BhardwajJournal of Cancer Research and Therapeutics 2018 14(3):709-711 Sinonasal malignant melanoma is one of the uncommon and highly aggressive tumors of the sinonasal cavity. Cytomorphological features in a metastatic lymph node may reveal a diagnosis of malignant melanoma. This case had nondiagnostic cytological and histopathological features, which could suggest malignant melanoma. Immunohistochemistry in such cases becomes the primary method for establishing the diagnosis of malignant melanoma at an uncommon site. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Prajwala Gupta Minakshi Bhardwaj Source Type: research

Dedifferentiated adenoid cystic carcinoma ex pleomorphic adenoma of the parotid
Minakshi Bhardwaj, Prajwala GuptaJournal of Cancer Research and Therapeutics 2018 14(3):706-708 Carcinoma ex pleomorphic adenoma (Ca ex PA) is defined as a carcinoma arising from a primary (de novo) or recurrent benign pleomorphic adenoma. The most common histological subtype is adenocarcinoma, not otherwise specified, salivary duct carcinoma, mucoepidermoid carcinoma, and adenoid cystic carcinoma (ACC). Few case reports of de novo dedifferentiation in ACC are there in the literature, mostly involving minor salivary glands. The dedifferentiated adenoid cystic carcinoma arising in a pleomorphic adenoma of the parotid gland...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Minakshi Bhardwaj Prajwala Gupta Source Type: research

Intermediate dose cytarabine in treatment myeloid sarcoma of the bilateral breast after allogeneic stem cell transplantation: A case report and literature review
Mozaffar Aznab, Mansour KhazaieJournal of Cancer Research and Therapeutics 2018 14(3):703-705 Myeloid sarcoma can be occurred bofore acute myeloid leukemia, concomitantly, at relapse or after allogenic stem cell transplantation, rarely. In this investigation, we reported a 38-year-old woman with a history of AML relapsed 9 months after allo-SCT as an MS in the bilateral breast. She underwent bilateral mastectomy. The patient was a candidate for systemic chemotherapy. An intermediate dose of cytarabine with mitoxantrone was considered for the patient, and it was repeated at the specified intervals. Currently, the patient i...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Mozaffar Aznab Mansour Khazaie Source Type: research

Benign mesenchymoma of bone: A rare case report
We report herein a rare case of benign mesenchymoma in the lower end of tibia in a 36-year-old female showing fibrous, fatty, and osseous elements. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Shirish Nandedkar Kamal Malukani Aparna Khandelwal Ashish Jain Source Type: research

Surgical resection of solitary distant metastasis from locoregionally controlled advanced hypopharyngeal malignancy: A ray of hope
Chelakkot G Prameela, Rahul Ravind, K Sruthi, Haridas M Nair, M DineshJournal of Cancer Research and Therapeutics 2018 14(3):697-700 Head and neck malignancies have always been challenging for the clinician, both with regards to locoregional control and distant metastasis. Aggressive approaches translate to an acceptable locoregional control, but distant failures pose a dilemma. Newer, sophisticated, imaging modalities have helped in early diagnosis of solitary metastasis, and in turn have opened up an array of interventional procedures, which to some extent improve the disease-free survival and quality of life, as was se...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Chelakkot G Prameela Rahul Ravind K Sruthi Haridas M Nair M Dinesh Source Type: research

Primary mesenchymal chondrosarcoma of the kidney: A case report and review of literature
We report a new case of this disease. A 35-year-old man, presented with flank pain, episodic gross hematuria and a painless palpable mass in left abdominal quadrant. Computed tomography scan identified a left renal tumor with 20 cm, with no evidence of regional or metastatic spread disease. The patient underwent radical nephrectomy. The immunohistopathological diagnosis was mesenchymal chondrosarcoma of the kidney. At 18 months of follow-up, there was no evidence of recurrence or distant metastasis. Primary renal chondrosarcoma is so rare that its prognosis is unknown. Disease recurrence is unpredictable and when it is det...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Pedro Valente Jos & #233; Ant & #243;nio Macedo-Dias Carlos Lobato M & #225;rio Reis Francisco Pina Source Type: research

Interdigitating dendritic cell tumor: A rare case report with review of literature
We report a case of a 35-year-old female who presented with right-sided neck swelling and anterior mediastinal mass. Histopathology revealed large mononucleated cells with background of mixed polymorphous inflammatory cells suspicious of Hodgkin's lymphoma. Hence, to confirm the diagnosis, immunohistochemistry was done. Immunohistochemistry revealed that the tumor was CD30 – negative, CD10 – negative, CD2 – negative, leukocyte common antigen – positive, vimentin – positive, and S-100 – positive, diagnostic of IDCT. Patient was treated with eight cycles of cyclophosphamide, doxorubici...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Irappa Madabhavi Apurva Patel Gaurang Modi Asha Anand Harsha Panchal Sonia Parikh Source Type: research

Glottic neurogenic tumor: A highly uncommon site for schwannomas
Shuchita Singh, Rakesh Kumar, Maitrayee Roy, Asit Ranjan MridhaJournal of Cancer Research and Therapeutics 2018 14(3):687-689 Schwannomas are benign encapsulated neurogenic tumors, arising from Schwann cells embedded in neurilemal sheath as multinucleated syncytial network. Head and neck schwannomas account for 25%–45% of all schwannomas, majority developing in parapharyngeal space. Laryngeal schwannoma in itself is a rarity, and a glottic origin further complicates its diagnosis. To the best of our knowledge, this is the second case of glottic schwannoma being reported in medical literature. Symptomatology ...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Shuchita Singh Rakesh Kumar Maitrayee Roy Asit Ranjan Mridha Source Type: research

Huge primary mediastinal synovial sarcoma fully occupying the right hemithorax
Ahmed Abu-Zaid, Asma AlNajjar, Sarah Alotaibi, Rasha Alshawaf, Noor Alqeshtaini, Rwan Alhaidar, Shamayel Mohammed, Khaled AlKattanJournal of Cancer Research and Therapeutics 2018 14(3):682-686 Primary mediastinal synovial sarcomas are exceedingly uncommon tumors. Herein, we present the case of primary mediastinal synovial sarcoma (monophasic spindle cell-shaped variant) fully occupying the right hemithorax in a 37-year-old woman who presented to clinic with a 2-month history of right-sided chest pain and shortness of breath. Although extremely rare, however, synovial sarcoma should be considered in the differential diagno...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Ahmed Abu-Zaid Asma AlNajjar Sarah Alotaibi Rasha Alshawaf Noor Alqeshtaini Rwan Alhaidar Shamayel Mohammed Khaled AlKattan Source Type: research

An atypical presentation of POEMS syndrome with IgG kappa type M protein and normal VEGF level: Case report and review of literature
We present an atypical case of POEMS syndrome with subclinical polyneuropathy, splenomegaly, hypogonadism, and myeloma of immunoglobulin G kappa type. The typical osteosclerotic lesions and skin lesions were absent, and vascular endothelial growth factor (VEGF) level was normal. Our patient also had chronic kidney disease due to focal segmental glomerulosclerosis. The patient died due to multisystem complications nine months after presenting with acute on chronic renal failure. POEMS syndrome is an uncommon, potentially fatal paraneoplastic syndrome presenting with plasma cell neoplasm and multisystem involvement. Despite ...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Swaroopa Pulivarthi Murali Krishna Gurram Source Type: research

Therapeutic effects of oleuropein on cisplatin-induced pancreas injury in rats
Conclusion: We hope that the results of this study will provide an impetus for future investigations of novel treatment strategies for OLE in pancreas due to CIS. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Murat Bakir Fatime Geyikoglu Kubra Koc Salim Cerig Source Type: research

A correlation of immunohistochemical expression of TP53 and CDKN1A in oral epithelial dysplasia and oral squamous cell carcinoma
Conclusion: The expression of TP53 in OED highlights its role in initial carcinogenesis. Although the role of CDKN1A in the cell cycle has been documented, its relationship to various clinical and pathological variables of OSCC and its different treatment modalities could not be adequately assessed. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Jay Ashokkumar Pandya Karen Boaz Srikant Natarajan Nidhi Manaktala KP Nandita Amitha J Lewis Source Type: research

Application of bi-nanoparticle on dose enhancement effect in two different polymer gel dosimeter using spectrophotometer
Conclusion: From our results, we infer that 0.5 mM is the optimal concentration in polymer gel to obtain good DEEs in the energy range of 1.25 MeV. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: P Sathiyaraj E James Jebaseelan Samuel Source Type: research

Antioxidant and anticancer activities of extract of Inula helenium (L.) in human U-87 MG glioblastoma cell line
Conclusion: The results strengthen the evidence that I. helenium could be considered a natural resource of potential antitumor agents for brain cancer. In addition, this study is expected to expand the existing information on the anticancer activity of I. helenium and to assist in a more focused design of further research as chemotherapeutic agents. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Kubra Koc Ozlem Ozdemir Aysenur Ozdemir Unsal Dogru Hasan Turkez Source Type: research

Modulation of risk of squamous cell carcinoma head and neck in North Indian population with polymorphisms in xeroderma pigmentosum complementation Group C gene
Conclusion: Our results suggest a possible risk modulation for SCCHN with XPC polymorphisms in North Indian population. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Suresh Kumar Yadav Sudhir Singh Shalini Gupta Madan Lal Brahma Bhatt Durga P Mishra D Roy Somali Sanyal Source Type: research

Validation of GATE for bone and bone marrow with calculation specific absorbed fraction for photons
Conclusion: In this study, the SAF values derived from GATE/GEANT and the corresponding MIRD published data were compared. On average, the SAF values derived with GATE/GEANT showed an acceptable correlation and agreement with the MIRD data for the photon energies of 50–1000 keV. For photons of 10–30 keV, there was an only poor agreement between the GATE/GEANT results and MIRD data. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Seydeh Zahra Ghaseminezhad Alireza Sadremomtaz Hossein Rajabi Source Type: research

Predictive polymorphisms for breast cancer in postmenopausal Mexican women
Conclusions: The presence of the G/G genotype of XbaI may be considered a susceptibility allele in Mexican women. Due to increased postmenopausal BC risk, the XbaI (WT/G or G/G) alleles may be used as a postmenopausal predictive factor for BC in Mexican women. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: M & #243;nica Sierra-Martinez Leticia Hern & #225;ndez-Cadena Jos & #233; Rub & #233;n Garc & #237;a-S & #225;nchez Gustavo Acosta-Altamirano Carmen Palacios-Reyes Patricia Garc & #237;a Alonso-Themann Liliana Garc & #237;a-Ortiz Laura Itzel Quintas-Grana Source Type: research

Assessment of accuracy of out-of-field dose calculations by TiGRT treatment planning system in radiotherapy
Conclusion: This study highlights the limitations of TiGRT TPSs in calculating of the out-of-field dose. It should be noted that out-of-field data for this TPS should only be applied with a certain understanding of the accuracy of calculated dose outside the treatment field. Therefore, using the TPS-calculated dose could lead to an underestimation of secondary cancer risk as well as a weak clinical decision for patients with implantable cardiac pacemakers or pregnant patients. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Mohammad Taghi Bahreyni Toossi Shokouhozaman Soleymanifard Bagher Farhood Shokoufeh Mohebbi David Davenport Source Type: research

Breast cancer tumor type recognition using graph feature selection technique and radial basis function neural network with optimal structure
Conclusions: The proposed system has a high recognition accuracy and therefore we recommend the proposed system for breast cancer tumor type recognition. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Payam Zarbakhsh Abdoljalil Addeh Source Type: research

The importance of stromal and intratumoral tumor lymphocyte infiltration for pathologic complete response in patients with locally advanced breast cancer
Conclusions: There is significantly an association between pCR and increased number of intratumoral TILs (>4 cells/mm 2 of tissue) in BC who received NACT. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Melek Karakurt Eryilmaz Hasan Mutlu Bet & #252;l & #220;nal Derya K & #305;vrak Salim Fatma Yal & #231; & #305;n Musri Hasan & #350;enol Co & #351;kun Source Type: research

RAD51 135G & #62;C polymorphism and risk of sporadic colorectal cancer in Iranian population
Conclusion: The results suggest that RAD51 135G>C probably has not a crucial role in Iranian CRC risk and is not an important potential risk factor in molecular diagnostics of mentioned disease among Iranian population. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Nasrin Yazdanpanahi Rasoul Salehi Sara Kamali Source Type: research

The clinical importance of serum urokinase plasminogen activator receptor and carbonic anhydrase IX levels and the effect of anthracycline-based adjuvant chemotherapy on these biomarkers in breast cancer
Turkan Ozturk Topcu, Feyyaz Ozdemir, Halil Kavgaci, Meral Gunaldi, Hakan Kocoglu, Goksen Inanc Imamoglu, Ahmet Mentese, Serap Ozer Yaman, Asim Orem, Fazil AydinJournal of Cancer Research and Therapeutics 2018 14(3):608-613 Introduction: Breast cancer mortality rates after metastasis is high. Urokinase plasminogen activator receptor (uPAR) and carbonic anhydrase IX (CAIX) play very important roles during tumor cell invasion and metastasis. The purpose of this study was to evaluate plasma levels of uPAR and CAIX and the effect of anthracycline-based chemotherapy on these biomarkers in patients with operable breast cancer. ...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Turkan Ozturk Topcu Feyyaz Ozdemir Halil Kavgaci Meral Gunaldi Hakan Kocoglu Goksen Inanc Imamoglu Ahmet Mentese Serap Ozer Yaman Asim Orem Fazil Aydin Source Type: research

Up-regulated expression of miR-155 in human colonic cancer
Conclusion: The expression of miR-155 is up-regulated in colonic cancer tissues. MiR-155 may acts as proto-oncogenes involved in carcinogenesis, development, and invasion of colon cancer making it a potential target for gene therapy of colon cancer. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Hongliang Cao Shaojun Huang Aihua Liu Zhidan Chen Source Type: research

Oral submucous fibrosis: A clinico-histopathological correlational study
Conclusion: The correlation of clinical and histopathological staging was found to be highly significant, thus suggesting that the subject with clinically advanced OSF had extensive fibrosis histologically. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Sudharani Basawaraj Biradar Anita Dnyanoba Munde Basawaraj Chanabasappa Biradar Safia Shoeb Shaik Shweta Mishra Source Type: research

Adjuvant chemotherapy for gastric cancer in elderly patients has same benefits as in younger patients
Conclusions: We showed that adjuvant chemotherapy in elderly patients with gastric cancer has same effectiveness as nonelderly patients. However, further well-designated prospective studies are needed to confirm these findings. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Mustafa Karaca Deniz Tural Hakan Kocoglu Fatih Selcukbiricik Irem Bilgetekin Ahmet & #214;zet Source Type: research

The clinical impact of serous tubal intraepithelial carcinoma on outcomes of patients with high-grade serous carcinoma of the ovary, fallopian tube, and peritoneum
Conclusions: The absolute identification of the origin of tumor cell does not seem to significantly affect the clinical course of the patients with HGSC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Tayfun Toptas Elif Pestereli Tayup Simsek Selen Bozkurt Gulgun Erdogan Seyda Karaveli Source Type: research

Role of human Cytomegalovirus in the etiology of nasopharyngeal carcinoma
Conclusion: The present study has shown a relatively considerable association between HCMV and NPC. The great majority of samples sheltering HCMV were also found to hide EBV, which proposes the potentiality of EBV over HCMV. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Hussain Gadelkarim Ahmed Rania Saad A Suliman Ibraheem M Ashankyty Zaid Ali Albieh Aymen A Warille Source Type: research

Prognostic factors of patients who received chemotherapy after cranial irradiation for non-small cell lung cancer with brain metastases: A retrospective analysis of multicenter study (Anatolian Society of Medical Oncology)
Conclusion: Smoking history, extracranial metastases, and neurosurgical resection were considered independent negative prognostic factors for OS. These findings may facilitate pretreatment prediction of survival and can be used for selecting patients for more appropriate treatment options. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Ali Inal Hilmi Kodaz Hatice Odabas Ayse Ocak Duran Mehmet Metin Seker Mevlide & #304;nanc Emin Tamer Elk & #305;ran Yusuf Gunayd & #305;n Serkan Menekse Turkan Ozturk Topcu Zuhat Urakc & #305; Didem Tastekin Mehmet Bilici Sener Cihan Caglayan Geredeli Eme Source Type: research

The diagnostic accuracy of colonoscopic brush cytology in diagnosis of colorectal malignancies: A study of 49 patients
Conclusion: Brush cytology is a reliable, safe, inexpensive, and rapid method of diagnosing gastrointestinal lesions. Since brushing is a relatively noninvasive procedure, routine use of brushings of colonoscopically visible lesions should be done, in addition, to biopsy to increase the diagnostic yield. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Simorjot Kaur Reetika Sharma Vijay Kaushal Anchana Gulati Brij Sharma Source Type: research

The value of serum survivin level in early diagnosis of cancer
Conclusion: Our study results may suggest that high serum survivin levels can show 4 times increased risk of cancer in a subject with a high suspicion of cancer. Furthermore, survivin level was not influenced with demographic characteristics of breast, gastric, colorectal, prostate, ovarian cancer, and glioblastome multiforme. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Meral Gunaldi Nilgun Isiksacan Hakan Kocoglu Yildiz Okuturlar Omur Gunaldi Turkan Ozturk Topcu Mehmet Karabulut Source Type: research

Percutaneous nephrostomy via the central venous catheter in combination with selective ureteroscopic lithotripsy for the treatment of ureteral stones in the middle-upper segment
Conclusion: Preoperative PCNL via the central venous catheter can significantly improve the success rate of ureteroscopic lithotripsy for the treatment of ureteral stones in the middle-upper segment, and reduce postoperative occurrences of severe infection and perirenal hematoma. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Dapang Rao Haifeng Yu Haibo Zhu Kaiyuan Yu Youhua He Ping Duan Source Type: research

The effect of gel homogeneity on dose response in a low-density polymer gel dosimeter for radiation therapy
Conclusion: Findings of the present study showed that if the density and homogeneity of the low-density polymer gel dosimeters are equal to those of the normal lung tissue, it may be used to measure the three dimensional dose distributions in lung tissue during radiation therapy. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Mehrdad Gholami Daryoush Shahbazi-Gahrouei Source Type: research

Malignancy associated hemophagocytic lymphohistiocytosis in children
Conclusion: The delay in the diagnosis of MA-HLH in pediatric patients may be due to decrease awareness about the condition the timely diagnosis of MA-HLH is crucial for a better outcome. Herein, we discuss our experience with this rare entity in pediatric oncology patients with review of literature. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Amitabh Singh Lesa Dawman Rachna Seth Source Type: research

In vivo autofluorescence of oral squamous cell carcinoma correlated to cell proliferation rate
Conclusion: A preliminary effort was attempted at delving into this relatively unexplored arena of optical biopsy systems through this study. They can be used to monitor treatment and potential complications, surgical margins, detection of nodal metastasis, etc. They can provide a diagnosis noninvasively, in situ, and in real time. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Kriti Bagri-Manjrekar Minal Chaudhary Gokul Sridharan Satyajit Raje Tekade Amol Ramchandra Gadbail Komal Khot Source Type: research

A survey of computed tomography dose index and dose length product level in usual computed tomography protocol
Conclusions: Using lower milli Amperes and higher kilo voltage peak as well as minimizing scan area and number of slices should be considered for more reduction in patients' dose. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Akbar Aliasgharzadeh Ehsan Mihandoost Mehran Mohseni Source Type: research

Comparing surgical outcome and ovarian reserve after laparoscopic hysterectomy between two methods of with and without prophylactic bilateral salpingectomy: A randomized controlled trial
Conclusion: Prophylactic bilateral salpingectomy at the time of laparoscopic hysterectomy neither has a negative effect on ovarian reserve nor increases the surgical risk. Therefore, we may recommend gynecologic surgeons to perform prophylactic bilateral salpingectomy during laparoscopic hysterectomy to conserve both ovaries. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Zahra Asgari Afsaneh Tehranian Safoura Rouholamin Reihaneh Hosseini Mahdi Sepidarkish Mahroo Rezainejad Source Type: research

Correlation of proliferative index with various clinicopathologic prognostic parameters in primary breast carcinoma: A study from North India
Conclusion: Based on our results, we concluded that modified Bloom–Richardson (MBR) grading has been recognized as a treatment related indicator. The accuracy and reliability in grading have always been a matter of concern, hence, the reproducibility of grading should be enhanced. Ki-67-a proliferation marker is easily identified and provides comparable accurate information. In contrast to poor reproducibility of mitotic counts, Ki-67 can achieve high agreement between pathologists; is more reproducible; adds complementary value to the MBR grading system and correlates well with other clinicopathologic parameters. It...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Nisha Marwah Ashima Batra Sanjay Marwah Veena Gupta Samta Shakya Rajeev Sen Source Type: research

The epidemiological and histological trend of bladder cancer in Iran
Conclusion: According to this study the trend of ASIR of bladder cancer in Iran is rising, so it is necessary to conduct further researches in future to provide accurate information on the cancer and investigate related risk factors and implement prevention programs in Iran. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Hosein Rafiemanesh Zahra Lotfi Sima Bakhtazad Mahshid Ghoncheh Hamid Salehiniya Source Type: research

Tooth agenesis: A susceptible indicator for colorectal cancer ?
Conclusion: Individuals with tooth agenesis might have an increased risk for CRC. A larger epidemiological study along with genetic mapping and gene sequencing is necessary to rule out the risk and relationship between tooth agenesis and CRC. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: MV Paranjyothi KL Kumaraswamy Lubna Firdose Begum K Manjunath Litha Shaini Basheer Source Type: research

Breast specific functional and symptom analysis in female breast cancer survivors
Conclusion: The female breast cancer survivors failed to improve their body image, sexual functioning, and sexual enjoyment scales but did well in other BR23 scales. Besides the family and spousal/marital support these patients got closer to their religion which has been seen to influence their psychosocial well-being optimistically and need further studies to establish the role of religious practices/beliefs. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Shaqul Qamar Wani Talib Khan Saiful Yamin Wani Mohammad Ashraf Teli Nazir Ahmad Khan Liza Rafiq Mir Mohammad Maqbool Lone Fir Afroz Source Type: research

Nuclear factor-kappa B as potential therapeutic target in human colon cancer
Conclusions: The expression NF-κB did not depend on the stage and grade of colon tumors. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Danuta Plewka Andrzej Plewka Adam Miskiewicz Micha & #322; Morek Edyta Bogunia Source Type: research

Evaluating the expression of cyclooxygenase-2 enzyme by immunohistochemistry in normal and tumoral tissue before and after neoadjuvant chemoradiotherapy in patients with esophageal cancer in Khorasan Province
Conclusions: The results indicated that expression of COX-2 in tumoral tissues exceeds the expression of COX-2 in normal tissue of the baseline biopsy. Patients with a high expression of COX-2 in baseline tumor biopsies had less response to treatment of pathology compared to patients with lower expression of COX-2 in baseline tumor biopsies. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Yousef Jalalabadi Alireza Shirazi Mohammad-Reza Ghavam-Nasiri Seyed Amir Aledavood Dariush Sardari Bahram Memar Soodabeh Shahidsales Fatemeh VarshoeeTabrizi Parvane Dehghan Hassan Vosughiniya Source Type: research

Hesperidin inhibits insulin-induced phosphoinositide 3 & #8211;kinase/Akt activation in human pre-B cell line NALM-6
Roghayeh Shahbazi, Makan Cheraghpour, Reza Homayounfar, Maryam Nazari, Javad Nasrollahzadeh, Sayed Hossein DavoodiJournal of Cancer Research and Therapeutics 2018 14(3):503-508 Context: It has been shown that hesperidin induces apoptosis in NALM-6 cells through inhibition of nuclear factor-kappa B (NF-κB) activation. Aims: To investigate the effect of hesperidin on inhibition of NF-κB activation through blocking phosphoinositide 3–kinase (PI3K)/Akt pathway as a main target in cancer treatment, in NALM-6 cells. Materials and Methods: NALM-6 cells were incubated with two concentrations of hesperidin (25, 5...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Roghayeh Shahbazi Makan Cheraghpour Reza Homayounfar Maryam Nazari Javad Nasrollahzadeh Sayed Hossein Davoodi Source Type: research

Immunohistochemical evaluation of tumor angiogenesis and the role of mast cells in oral squamous cell carcinoma
Arpita Kabiraj, Rohit Jaiswal, Anil Singh, Jagriti Gupta, Arun Singh, Fahad M SamadiJournal of Cancer Research and Therapeutics 2018 14(3):495-502 Background: Increased angiogenesis has been associated with neoplastic progression, metastasis and outcome in several studies and in a number of malignancies. Among the various host immune cells, mast cells have been implicated in tumor progression by promoting angiogenesis. The aim of this study is to examine the relationship between angiogenesis, mast cells with that of the normal oral mucosa (NOM) and oral squamous cell carcinoma (OSCC). Materials and Methods: The study was...
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Arpita Kabiraj Rohit Jaiswal Anil Singh Jagriti Gupta Arun Singh Fahad M Samadi Source Type: research

Effects of food insecurity on the women esophageal cancer in the Zanjan Province
Conclusion: Our findings showed an association of food insecurity and body mass index (BMI) in the study population. Food insecurity increased the rate of underweight and decreased the rates of overweight and obesity. (Source: Journal of Cancer Research and Therapeutics)
Source: Journal of Cancer Research and Therapeutics - June 12, 2018 Category: Cancer & Oncology Authors: Amir Najafi Source Type: research