Sustained-Release Corticosteroids for Cataract Surgery in the Medicare Pass-Through Program
This cross-sectional study examines the use and cost of sustained-release corticosteroids for cataract surgery within the Medicare pass-through program. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Effect of High-Dose Intravitreal Aflibercept, 8 mg, in Patients With Neovascular Age-Related Macular Degeneration
This randomized clinical trial assesses the safety and efficacy of aflibercept, 8 mg, in patients with neovascular age-related macular degeneration. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Accuracy of Vitreoretinal Disease Information From AI Chat-Based Program
This cross-sectional study compares 2 sets of responses by 1 chatbot to frequently asked questions about vitreoretinal conditions and procedures. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Pass-Through Payments, Cost, and Convenience in Hospital Outpatient Departments and Ambulatory Surgical Centers
The US Medicare pass-through program applies to new drugs that are used in hospital outpatient departments (HOPDs) or ambulatory surgical centers (ASCs) under Medicare Part B. These facilities are normally paid for by the Centers for Medicare& Medicaid Services (CMS) under the applicable ambulatory payment classification (APC). The pass-through program provides a mechanism by which the cost of new drugs administered in the HOPD or ASC is passed through to CMS. In so doing, CMS supports the availability of new drugs for beneficiaries during a defined initial period during which their use and impacts can be assessed. (So...
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
The CANDELA Study —Trends and End Points
As we progress into the next era of treatments for retinal vascular diseases, we strive to find options that have both better durability and efficacy as well as fewer visits. The bar is already high with the first generation of anti –vascular endothelial growth factor (VEGF) molecules. Wykoff et al present the results of the Safety, Tolerability, and Efficacy of Aflibercept in Patients With Neovascular Age-Related Macular Degeneration (CANDELA) study, which evaluates 8-mg aflibercept compared with 2-mg aflibercept in a fixed- dosing schedule for the treatment of neovascular age-related macular degeneration. The primary e...
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Assessing Strategies to Reduce Carbon Footprint of the AAO Annual Meeting
This quality improvement study compares greenhouse gas emissions between in-person and virtual meetings of the American Academy of Ophthalmology (AAO) and investigates what adjustments may be associated with reduced emissions. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Silicone Oil Droplet Floaters Following Intravitreal Injection
This case series analyzes the presence of floaters associated with silicone oil droplets after intravitreal pegcetacoplan injection. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Further Reflections on Sustainability in Ophthalmology
The emission of greenhouse gases that are associated with climate change is of increasing concern. Threats to the future associated with industrialization have compelled us all to seek ways to mitigate our carbon footprint. While many aspects of medicine contribute to climate change, there is a concerted movement toward identifying where savings in contributions to environmental demise can be recognized, such as waste in operating rooms and medical meetings. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Considering the Carbon Footprint of Ophthalmology Conferences
In recent years, increasing attention has been directed toward the roles and responsibilities of medical professionals when it comes to climate change. In the field of ophthalmology, much of the focus to date has been on the clinical and surgical use of resources and materials as a high-volume procedural specialty. McClintic and Stashevsky highlight a different but important aspect of ophthalmologists ’ carbon footprint that has little to do with direct clinical or surgical care. These authors consider the impact of holding in-person vs virtual medical conferences on climate and discuss whether meeting locations can be d...
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Deep Ocular Phenotyping Across Primary Open-Angle Glaucoma Genetic Burden
This cross-sectional study investigates how the phenotypic features of patients vary across genetic burden for primary open-angle glaucoma. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
GJA3 Genetic Variation and Autosomal Dominant Congenital Cataracts and Glaucoma Following Cataract Surgery
This genetic association study assesses the family members in a 4-generation pedigree with congenital cataracts caused by a GJA3 variant who have a remarkably high incidence of glaucoma following cataract surgery in early childhood. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Three-Dimensional Structural Phenotype of the Optic Nerve Head as a Function of Glaucoma Severity
This cross-sectional study examines optical coherence tomography images to describe 3-dimensional structural differences in both connective and neural tissues of the optic nerve head using traditional clinician-defined and artificial intelligence approaches. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Association Between Health Insurance and Vision Testing
This survey study assesses rates of vision testing by pediatrician or other primary care practitioners among insured and uninsured persons aged 3 to 17 years. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Glaucoma Following Cataract Surgery in Children —Finally, a Clue
Childhood cataract is among the more common treatable causes of childhood visual disability and blindness, representing some 10% to 15% of children enrolled globally in schools for blind individuals. Congenital cataracts are genetically heterogeneous with 234 entries on Online Mendelian Inheritance in Man using the search terms congenital cataract. They may be isolated, associated with other ocular anomalies such as microphthalmia or sclerocornea, or be a part of systemic disorders such as trisomy 21 or Lowe syndrome. Some are associated with metabolic conditions such as galactosemia or cerebrotendinous xanthomatosis that ...
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
Increasing Role of OCT in Glaucoma Diagnostics and Disease Progression
Understanding structural changes in the optic nerve head, peripapillary retina, and macula due to glaucoma is important not only for diagnosis and management but also for insight on glaucoma pathophysiology. Studies in experimental glaucoma have provided significant clues on the sequence of neuronal and nonneuronal events in these tissues that clinicians recognize as glaucomatous neuropathy. However, the limitations of experimental glaucoma regarding applicability to humans and limitations of clinical studies that do not permit adequate parallel clinical and histological analyses means that an inevitable knowledge gap exis...
Source: JAMA Ophthalmology - September 1, 2023 Category: Opthalmology Source Type: research
