Incidence and Risk Factors for Neutropenia After Intra-Arterial Chemotherapy for Retinoblastoma
This case series examines the incidence of neutropenia after intra-arterial chemotherapy in pediatric patients with retinoblastoma and risk factors for disease occurrence. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Pathogen Surveillance for Acute Infectious Conjunctivitis
This cross-sectional study examines the microbial etiologies of acute infectious conjunctivitis at 4 sites in the US and 1 site in Israel. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Fever and Neutropenia Can Be a Risk to the Child ’s Life
Lee and colleagues report a 39.4% rate of grade 3 or 4 neutropenia following 171 cycles of intra-arterial chemotherapy (IAC) administered to 49 patients with retinoblastoma. The most recent version of the Common Terminology Criteria for Adverse Events (CTCAE) classifies grade 3 neutropenia as an absolute neutrophil count of 500 to less than 1000 and grade 4 as an absolute neutrophil count of less than 500. Most cycles (72%) in this retrospective single-institution case series used triple drug therapy with melphalan, topotecan, and carboplatin. Multivariate regression analysis showed more grade 3 or 4 neutropenia with highe...
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Psychiatric Comorbidities Associated With Keratoconus
This cross-sectional study assesses whether risk for keratoconus is higher in adolescents and adults with psychiatric comorbidities. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Risk of New Retinal Vascular Occlusion After Messenger RNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data —Reply
In Reply We appreciate the letters regarding our article by Dorney et al in which messenger RNA (mRNA) COVID-19 vaccinations were not associated with retinal vascular occlusions (RVO). To summarize, the concerns with our study are in relation to Li and colleagues ’ comparable article, our choice of a 21-day time frame and the association between first and second vaccination, evaluation of confounder variables, and control group selection. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data
To the Editor We have several comments regarding the article by Dorney et al. First, the study investigated the potential link between messenger RNA (mRNA) COVID-19 vaccination and the risk of retinal vein occlusion (RVO) through a retrospective cohort design involving 4 cohort groups. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Risk of New Retinal Vascular Occlusion After mRNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data
To the Editor We read with great interest a recent study by Dorney et al, concluding that there was no association between messenger RNA (mRNA) COVID-19 vaccination and newly diagnosed retinal vascular occlusion (RVO) with similar rates compared with those following influenza and tetanus, diphtheria, and pertussis (Tdap) vaccines. However, we have several methodological concerns and suggestions. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Risk of New Retinal Vascular Occlusion After Messenger RNA COVID-19 Vaccination Within Aggregated Electronic Health Record Data
To the Editor We read with interest the article by Dorney et al. We would like to report some potentially relevant information that was published by our colleagues soon after their publication. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Large Language Model Advanced Data Analysis Abuse to Create a Fake Data Set in Medical Research
This quality improvement study evaluates the ability of GPT-4 Advanced Data Analysis to create a fake data set that can be used for the purpose of scientific research. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
IOP in Eyes With RVO Compared With Fellow Eyes
This cohort study investigates intraocular pressure (IOP) in eyes with retinal vein occlusion (RVO) compared with fellow, unaffected eyes. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Do Not Think of a Purple Wolf —Keratoconus, ADHD, and Itch
Do not think of a purple wolf. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Social Determinants of Health and Perceived Barriers to Care in Diabetic Retinopathy Screening
This cross-sectional study examines the factors related to social determinants of health that are associated with visiting an eye care practitioner among patients with type 2 diabetes. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Efficacy and Safety of Brolucizumab for Diabetic Macular Edema
This randomized clinical trial evaluates the efficacy and safety of brolucizumab vs aflibercept dosed every 4 weeks in participants with diabetic macular edema. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
JAMA Ophthalmology
Mission Statement: To be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and, thereby, to be the first choice of authors for their important manuscripts. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
Error in the Abstract
This article was corrected online. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - December 1, 2023 Category: Opthalmology Source Type: research
