OCT Feature of Retinoschisis in CRB1 -Associated Maculopathy
This case report describes 2 individuals with hyperreflective columns in the outer nuclear layer observed on optical coherence tomography and possible implications for CRB1-associated maculopathy. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Investigation of Population-Based Fall Risk in Eye Diseases
It is well-known that older adults are at higher risk of falls and resulting injuries. Falls and their aftermath are one of the major public health concerns in aging societies. The aging-related risk of falls and fractures can be attributed to factors such as deteriorating muscle strength, balance, and vision. One way to further break down the vision factor can be by age-related eye diseases such as cataract, age-related macular degeneration (AMD), and glaucoma. Given their rapidly increasing prevalence, understanding the risk of falls by diagnosis of these eye diseases has clinical and societal importance. However, popula...
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Emerging Role of Axial Length Trajectories in the Management of Myopia
Parents and those in the health care sector who work with children will be familiar with childhood growth curves for height and weight. These normative values have existed since the late 19th century and can help predict various disorders such as undernutrition, obesity, and growth-related or endocrine conditions. Normative values can guide diagnosis and allow for timely interventions. Given the association of increased axial length with myopia, is it feasible and worthwhile to add axial length trajectory to standard childhood reference data? (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Incidental Genetic Finding in a Fetus
A 37-year-old woman presented with suspected polycystic kidney detected on routine fetal ultrasonography, and an incidental finding of a heterozygous c.501-2 A<G sequence variant in the RB1 gene was noted. What would you do next? (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Green Space Morphology and School Myopia in China
This cohort study evaluates the associations between myopia and specific green space morphology using novel quantitative data from high-resolution satellite imaging. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Alzheimer Disease Treatment With Acetylcholinesterase Inhibitors and Incident AMD
This cohort study investigates the association between acetylcholinesterase inhibitor medications and the incidence of age-related macular degeneration. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Silicone Oil From Syringes —a Potentially Overlooked Issue for Intravitreal Injections—Reply
In Reply We would like to thank Melo et al for their interest in our recent publication entitled “Multiple Small Floaters Associated with Silicone Oil Droplets Following Intravitreal Pegcetacoplan Injection.” We share their concerns regarding the occurrence of symptomatic silicone oil droplets (SODs) following intravitreal injections (IVIs) of various ocular medications. In our report, we h ypothesized that repeated up and down movements of the syringe plunger intended to eliminate gas bubbles, combined with pegcetacoplan’s high viscosity, contributed to the occurrence of intravitreal SODs. In a previous report, Melo...
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Silicone Oil From Syringes —A Potentially Overlooked Issue for Intravitreal Injections
To the Editor The study conducted by Bijon et al addresses a potentially important and underestimated issue pertaining to intravitreal injections (IVIs). Given the substantial number of IVI procedures performed globally, even seemingly minor concerns might merit attention. For instance, the 2018 American Society of Retina Specialists Preferences and Trends survey revealed that 60% of US retina specialists had encountered at least 1 patient with silicone oil (SO) droplets following IVI of bevacizumab, 5% had resorted to vitrectomy to manage symptomatic floaters secondary to SO, and 2% had witnessed patients pursuing legal a...
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Conjunctival Biopsy of a Patient With Mpox
This case report describes a conjunctival biopsy of a patient with mpox infection. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Epidermal Growth Factor Receptor Inhibitors for Lung Cancer and Keratitis Risk
This cohort study evaluated the risk of new-onset keratitis among patients with lung cancer treated with epidermal growth factor receptor inhibitors. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Sex Disparities in Ophthalmology From Training Through Practice
This systematic review investigates the experiences of females in ophthalmology in high-income countries, from training through practice. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Intra-Anterior Chamber Injection of Ranibizumab in Advanced Pediatric Vitreoretinal Diseases
This case series evaluates the use of intra-anterior chamber injection of anti –vascular endothelial growth factor in the treatment of pediatric vitreoretinal diseases. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Sex or Gender Reporting in Ophthalmology Clinical Trials Among US FDA, 1995 to 2022
This study attempts to evaluate the accuracy of sex and gender reporting and extent of sex- and gender-based analysis in clinical trials associated with US Food and Drug Administration drug approvals between January 1, 1995, and December 31, 2022. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Suggested Principles for Sex and Gender Data in Ophthalmology Clinical Trials
Xie et al assessed how sex or gender terminology were applied in ophthalmology clinical trials associated with US Food and Drug Administration (FDA) drug approvals. Sex is a biological construct that is based on physiology, anatomy, hormones, and genetics. Gender is a multidimensional construct encompassing both gender expression and identity. Xie and colleagues reported that sex and gender terms were applied incorrectly (using sex and gender interchangeably, sex-related terms in reference to gender, and gender-related terms in reference to sex) 80.5% of the time in 85 clinical trials. They also found that while 96.5% of c...
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
JAMA Ophthalmology
Mission Statement: To be the indispensable source of ophthalmic knowledge by promptly publishing innovative, clinically relevant research through consistent and authoritative peer review and, thereby, to be the first choice of authors for their important manuscripts. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
