Pegcetacoplan for Treatment of Geographic Atrophy Growth
On December 7, 2023, Schachar published a Viewpoint, “Concerning Syfovre Approval for Geographic Atrophy,” online first in JAMA Ophthalmology. Schachar noted that pegcetacoplan (Syfovre) had recently been approved by the US Food and Drug Administration as a treatment to slow the rate of geographic atrophy (GA) growth, but not as a treatment for im proving visual acuity or reducing the risk of visual acuity loss. He cautioned about potential safety and efficacy concerns that might give clinicians pause, and he advised, “While there is a pressing need for an effective, safe treatment for GA, it is important to exercise...
Source: JAMA Ophthalmology - February 1, 2024 Category: Opthalmology Source Type: research
Unilateral Diffuse Pigmentary Retinopathy Associated With Optic Disc Pit
This case report describes a diagnosis of pigmentary retinopathy and optic disc pit in a woman aged 41 years who presented with long-standing decreased vision in the left eye. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 18, 2024 Category: Opthalmology Source Type: research
Retinopathy Associated With Coxsackie B Virus Infection
This case report describes a diagnosis of unilateral retinopathy secondary to coxsackie B virus in a male patient aged 41 years who presented with a central scotoma and blistering rash of the hands, feet, and mouth for 4 days. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 18, 2024 Category: Opthalmology Source Type: research
Pigmented Squamous Cell Carcinoma in Situ of the Eyelid
This case report describes a diagnosis of pigmented squamous cell carcinoma in situ in a female patient aged 61 years who presented with a pigmented lesion on her medial canthus that had been growing over a 2-year period. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 18, 2024 Category: Opthalmology Source Type: research
Foveal Pseudoduplication in a Young Male Patient
This case report describes a diagnosis of pseudofovea found on examination in an otherwise asymptomatic young male patient. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 18, 2024 Category: Opthalmology Source Type: research
Surgical Approach and Reoperation Risk in Intermittent Exotropia in the IRIS Registry
This cohort study examines the risk of reoperation in children with intermittent exotropia associated with bilateral lateral rectus recession compared with unilateral lateral rectus recession with medial rectus resection. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Genetic Counseling For Predictive Retinal Imaging
This Viewpoint discusses genetic counseling for predictive retinal imaging. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Rising Incidence of Syphilitic Uveitis –Related Hospitalizations in the US
This cross-sectional study uses patient data from the Nationwide Inpatient Sample to investigate the national and regional incidence of syphilitic uveitis in the US from 2010 to 2019. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Topical Atropine for Childhood Myopia Control
This study reports long-term safety and outcomes of topical atropine for childhood myopia control. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Sociodemographic Characteristics Distinguished From Social Determinants of Health
To the Editor We appreciate the commentary from Kemper et al, who raise 2 points that we would like to clarify. The commenters stress the importance of differentiating between social risk factors and sociodemographic characteristics and note that researchers should be careful not to equate social determinants of health (SDOH) with membership in a minoritized racial or ethnic group. For those reasons, our study distinguished between the sociodemographic characteristics, including race and ethnicity, and the SDOH that we included in our analyses. Although we mistakenly referred to race and ethnicity as an SDOH along with oth...
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Atropine Eye Drops for Myopia Control in Childhood —More Long-Term Data, Please
The Atropine Treatment Long-Term Assessment Study (ATLAS) has provided important very-long-term outcome data concerning the effectiveness and safety for prescribing various concentrations of atropine eye drops (0.01%, 0.1%, 0.5%, and 1.0%) for myopia control. The study findings affirm the importance of randomized short-term treatment trials complemented with long-term follow-up of participants whenever the medical condition being studied may continue to progress after stopping the intervention. In the instance of myopia control treatment, progression may be expected to continue for up to 2 decades after completing the rand...
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Metformin Use and Age-Related Macular Degeneration in Patients Without Diabetes
This case-control study uses data from a nationwide claims database to investigate the risk of developing age-related macular degeneration in patients without diabetes who take metformin. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Global, Regional, and National Epidemiology of Visual Impairment
This cross-sectional study uses Global Burden of Disease data to investigate trends in visual impairment prevalence and disability-adjusted life-years among working-age people. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Error in Text
This article was corrected online. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
Local Firework Restrictions and Ocular Trauma
This case-control study evaluates the odds of firework-related ocular trauma among residents of areas where fireworks are permitted vs banned. (Source: JAMA Ophthalmology)
Source: JAMA Ophthalmology - January 1, 2024 Category: Opthalmology Source Type: research
