Increasing Role of OCT in Glaucoma Diagnostics and Disease Progression

Understanding structural changes in the optic nerve head, peripapillary retina, and macula due to glaucoma is important not only for diagnosis and management but also for insight on glaucoma pathophysiology. Studies in experimental glaucoma have provided significant clues on the sequence of neuronal and nonneuronal events in these tissues that clinicians recognize as glaucomatous neuropathy. However, the limitations of experimental glaucoma regarding applicability to humans and limitations of clinical studies that do not permit adequate parallel clinical and histological analyses means that an inevitable knowledge gap exists.
Source: JAMA Ophthalmology - Category: Opthalmology Source Type: research