Association of cerebrospinal fluid CD4+/CD8+Ratio with 60-day functional outcome after intracerebral hemorrhage
Conclusions: In association of critical ICH patient prognosis, CSF CD4/CD8 ratio, especially in 3-5 days after surgery, exhibited potential independent predictive ability for 60-day functional outcomes of patients with critical ICH.PMID:37853743 | DOI:10.1177/03946320231207350 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 19, 2023 Category: Allergy & Immunology Authors: Chunying Zhu Wei Li Yingfu Zhang None Qianqian Li Huan Wang Source Type: research

Revolutionizing antiretroviral therapy for human immunodeficiency virus/AIDS: A computational approach using molecular docking, virtual screening, and 3D pharmacophore building to address therapeutic failure and propose highly effective candidates
CONCLUSION: The combination of molecular docking, virtual screening, and 3D pharmacophore modeling yielded lead compounds that hold potential for addressing HIV therapeutic failures. Further experimental investigations are essential to validate the efficacy and safety of these compounds, with the ultimate goal of advancing toward clinical applications in HIV management.PMID:37850462 | DOI:10.1177/03946320231207514 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 18, 2023 Category: Allergy & Immunology Authors: Azzeddine Annan Noureddine Raiss El Harti Elmir Abdelkarim Filali-Maltouf Leila Medraoui Hicham Oumzil Source Type: research

Follow the time course of inflammation caused by intraperitoneal administration of multi-wall carbon nanotubes in mice
CONCLUSION: Three months post-exposure becomes a turning point for the harmful effects of the intraperitoneally administered MWCNT-7.PMID:37846071 | DOI:10.1177/03946320231176402 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 17, 2023 Category: Allergy & Immunology Authors: Masanori Horie Sakiko Sugino Tomoki Ohno Source Type: research

Prognostic and immunological role of acetaldehyde dehydrogenase 1B1 in human tumors: A pan-cancer analysis
In this study, we investigated the expression and prognostic value of ALDH1B1 in pan-cancer specimens using several databases, including GEPIA2 and Kaplan-Meier Plotter. The GEPIA2 and TIMER2 databases were used to explore correlations between ALDH1B1 expression and immune infiltration in cancers, especially head and neck squamous cell carcinoma (HNSC) and stomach adenocarcinoma (STAD). Finally, the expression of ALDH1B1 was validated by qPCR and immunohistochemistry. The expression of ALDH1B1 differed in most cancers compared to normal tissue controls. ALDH1B1 has an important impact on the prognosis different cancer type...
Source: International Journal of Immunopathology and Pharmacology - October 17, 2023 Category: Allergy & Immunology Authors: Yong Kuang Jiahao Feng Yuhong Jiang Qianqian Jin Qi Wang Changhua Zhang Yulong He Source Type: research

Follow the time course of inflammation caused by intraperitoneal administration of multi-wall carbon nanotubes in mice
CONCLUSION: Three months post-exposure becomes a turning point for the harmful effects of the intraperitoneally administered MWCNT-7.PMID:37846071 | DOI:10.1177/03946320231176402 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 17, 2023 Category: Allergy & Immunology Authors: Masanori Horie Sakiko Sugino Tomoki Ohno Source Type: research

METTL3-mediated m < sup > 6 < /sup > A modification of lncRNA SNHG3 accelerates gastric cancer progression by modulating miR-186-5p/cyclinD2 axis
CONCLUSION: We find that METTL3-mediated m6A modification of lncRNA SNHG3 accelerates GC progression by modulating miR-186-5p/cyclinD2 axis.PMID:37823387 | PMC:PMC10571673 | DOI:10.1177/03946320231204694 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 12, 2023 Category: Allergy & Immunology Authors: Guo Ji Xiu Wang Hao Xi Source Type: research

METTL3-mediated m < sup > 6 < /sup > A modification of lncRNA SNHG3 accelerates gastric cancer progression by modulating miR-186-5p/cyclinD2 axis
CONCLUSION: We find that METTL3-mediated m6A modification of lncRNA SNHG3 accelerates GC progression by modulating miR-186-5p/cyclinD2 axis.PMID:37823387 | DOI:10.1177/03946320231204694 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 12, 2023 Category: Allergy & Immunology Authors: Guo Ji Xiu Wang Hao Xi Source Type: research

Drug reintroduction testing and beta-lactam hypersensitivity in children: Protocols and results, a 12-year experience
Conclusion: An OPT to BL indicated in the first instance in non-severe reaction in children will allow a rapid diagnosis in case of suspicion of HS to BL.PMID:37789550 | PMC:PMC10552452 | DOI:10.1177/03946320231204220 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - October 4, 2023 Category: Allergy & Immunology Authors: Hafaoua Daghfous Chirine Moussa Amani Ben Mansour Azza Slim Soumaya Ben Saad Fatma Tritar Source Type: research