International Journal of Immunopathology and Pharmacology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Macrophage-derived exosomal miRNA-141 triggers endothelial cell pyroptosis by targeting NLRP3 to accelerate sepsis progression
Int J Immunopathol Pharmacol. 2024 Jan-Dec;38:3946320241234736. doi: 10.1177/03946320241234736.ABSTRACTSepsis, critical condition marked by severe organ dysfunction from uncontrolled infection, involves the endothelium significantly. Macrophages, through paracrine actions, play a vital role in sepsis, but their mechanisms in sepsis pathogenesis remain elusive. Objective: We aimed to explore how macrophage-derived exosomes with low miR-141 expression promote pyroptosis in endothelial cells (ECs). Exosomes from THP-1 cell supernatant were isolated and characterized. The effects of miR-141 mimic/inhibitor on apoptosis, prolif...
Source: International Journal of Immunopathology and Pharmacology - April 23, 2024 Category: Allergy & Immunology Authors: Feng Zhan Jun Zhang Ping He Wenteng Chen Yanhong Ouyang Source Type: research

Effect of overweight/obesity on relationship between fractional exhaled nitric oxide and airway hyperresponsiveness in Chinese elderly patients with asthma
Conclusion: The elderly Chinese Han asthmatics with overweight/obesity had lower FeNO levels than those with non-obese according to our findings. In addition, the FeNO level was inversely correlated between FeNO levels and PC20 in elderly asthmatics.PMID:38649141 | DOI:10.1177/03946320241246713 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - April 22, 2024 Category: Allergy & Immunology Authors: Fengjia Chen Yangli Liu Long-Hua Sun Zhimin Zeng Xinyan Huang Source Type: research

Impact of IL-10 gene promoter polymorphisms on treatment response in HCV patients: A systematic review, a meta-analysis, and a meta-regression
Int J Immunopathol Pharmacol. 2024 Jan-Dec;38:3946320241240705. doi: 10.1177/03946320241240705.ABSTRACTThe impact of interleukin-10 (IL-10) gene promoter polymorphisms (SNPs) on treatment response in HCV patients was dissimilarly estimated. Hence, the aim of this meta-analysis was to robustly assess the effect of IL-10 SNPs on treatment response in HCV patients. An electronic literature search was carried out through PubMed, EMBASE, Web of science, and Scopus databases. Studies assessing the association between IL-10 polymorphisms and treatment response in HCV patients were included. Studies were excluded if genotype frequ...
Source: International Journal of Immunopathology and Pharmacology - March 23, 2024 Category: Allergy & Immunology Authors: Tarak Dhaouadi Awatef Riahi Ta ïeb Ben Abdallah Yousr Gorgi Imen Sfar Source Type: research