Use of canakinumab and remdesivir in moderate-severe COVID-19 patients: A retrospective analysis
Conclusions: Canakinumab and remdesivir treatment, in addition to SOC, in the early stage of moderate-to-severe COVID-19 showed promising outcomes in terms of safety and effectiveness potentially leading to a reduction in inflammatory and hematological prognostic markers after 7 days of treatment.PMID:37534444 | DOI:10.1177/03946320231189993 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Antonio Mastroianni Valeria Vangeli Luciana Chidichimo Filippo Urso Giuseppe De Marco Alfredo Zanolini Francesca Greco Maria V Mauro Sonia Greco Source Type: research

Penehyclidine hydrochloride protects against lipopolysaccharide-induced acute lung injury by promoting the PI3K/Akt pathway
CONCLUSION: PHC significantly activates the PI3K/Akt pathway to ameliorate the extent of damage to pulmonary tissue, inflammation, oxidative stress, apoptosis, and ERS in LPS-induced ALI.PMID:37500500 | DOI:10.1177/03946320231192175 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - July 27, 2023 Category: Allergy & Immunology Authors: Junting Weng Danjuan Liu Bingbing Shi Min Chen Shuoyun Weng Rongjie Guo Chunjin Fu Source Type: research

Increased circulating levels of MIP-1 α and CD14 are associated with the presence of severe stenosis and hypoechoic plaques in patients with carotid atherosclerosis
CONCLUSIONS: Our data suggest that circulating MIP-1α and CD14 levels are associated with the presence of advanced stenosis and of vulnerable carotid plaques.PMID:37478026 | PMC:PMC10363894 | DOI:10.1177/03946320231160411 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - July 21, 2023 Category: Allergy & Immunology Authors: Elisabetta Profumo Brigitta Buttari Maria Elena Tosti Bruno Salvati Raffaele Capoano Rachele Rigan ò Source Type: research

Increased circulating levels of MIP-1 α and CD14 are associated with the presence of severe stenosis and hypoechoic plaques in patients with carotid atherosclerosis
CONCLUSIONS: Our data suggest that circulating MIP-1α and CD14 levels are associated with the presence of advanced stenosis and of vulnerable carotid plaques.PMID:37478026 | DOI:10.1177/03946320231160411 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - July 21, 2023 Category: Allergy & Immunology Authors: Elisabetta Profumo Brigitta Buttari Maria Elena Tosti Bruno Salvati Raffaele Capoano Rachele Rigan ò Source Type: research