Multiple sclerosing hemangiomas mimicking hepatocellular carcinoma: A case report
Int J Immunopathol Pharmacol. 2023 Jan-Dec;37:3946320231190898. doi: 10.1177/03946320231190898.ABSTRACTHepatocellular carcinoma is a prevalent malignant tumor affecting the liver, and surgical resection and liver transplantation are the primary treatment options for early-stage HCC patients. However, the presence of benign hepatic tumors with similar imaging characteristics to HCC poses challenges in diagnosing and treating the disease, often resulting in misdiagnosis and inappropriate treatment. This case report presents a 52-year-old female patient who exhibited space-occupying liver lesions on abdominal CT and MRI scans...
Source: International Journal of Immunopathology and Pharmacology - August 24, 2023 Category: Allergy & Immunology Authors: Xinyu Zhan Yiyun Gao Jian Xu Dongming Wu Ping Wang Haoming Zhou Source Type: research

Outcomes of dexmedetomidine as adjuvant drug in patients undergoing videolaparoscopic cholecystectomy: A randomized and prospective clinical trial
CONCLUSIONS: Dexmedetomidine provided anti-inflammatory benefits and contributed to postoperative analgesia without the depressive side effects on the respiratory and cardiovascular systems commonly observed with opioids.TRIAL REGISTRATION: Immunomodulatory Effect of Dexmedetomidine as an Adjuvant Drug in Laparoscopic Cholecystectomies, NCT05489900, Registered 5 August 2022-Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT05489900?term=NCT05489900&draw=2&rank=1.PMID:37604516 | DOI:10.1177/03946320231196977 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - August 21, 2023 Category: Allergy & Immunology Authors: Gustavo Nascimento Silva Virna Guedes Brand ão Rossano Fiorelli Marcelo Vaz Perez Carolina Ribeiro Mello Daniel Negrini Kai-Uwe Levandrowski Rafael Bof Martinelli Tatiana Pereira do Amaral Dos Reis Source Type: research

Changes in serum hypoxia-inducible factor-1 α and erythropoietin in allergic rhinitis patients: Correlation with the Th inflammatory profile and disease comorbidities
CONCLUSION: These results confirmed a pathogenic implication for HIF-1α and IFN-γ in AR that warranted future bigger and longitudinal studies.PMID:37596741 | PMC:PMC10440105 | DOI:10.1177/03946320231196745 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - August 19, 2023 Category: Allergy & Immunology Authors: Abdullah N Al-Rasheedi Abdulrahman H Almaeen Abdullah D Alotaibi Abdulaziz S D Alruwaili Sultan H H Alruwaili Wadad M A Alruwaili Aljoharah S Alsakhry Ghuyudh M Alruwaili Hala M ALkuwaykibi Noof N Alrawili Rahaf Z Alabdullah Reem S Alatwi Ibrahim Taher Ta Source Type: research

Changes in serum hypoxia-inducible factor-1 α and erythropoietin in allergic rhinitis patients: Correlation with the Th inflammatory profile and disease comorbidities
CONCLUSION: These results confirmed a pathogenic implication for HIF-1α and IFN-γ in AR that warranted future bigger and longitudinal studies.PMID:37596741 | DOI:10.1177/03946320231196745 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - August 19, 2023 Category: Allergy & Immunology Authors: Abdullah N Al-Rasheedi Abdulrahman H Almaeen Abdullah D Alotaibi Abdulaziz S D Alruwaili Sultan H H Alruwaili Wadad M A Alruwaili Aljoharah S Alsakhry Ghuyudh M Alruwaili Hala M ALkuwaykibi Noof N Alrawili Rahaf Z Alabdullah Reem S Alatwi Ibrahim Taher Ta Source Type: research

MiR-183-5p promotes renal cell carcinoma metastasis by targeting TET1
Int J Immunopathol Pharmacol. 2023 Jan-Dec;37:3946320231184997. doi: 10.1177/03946320231184997.ABSTRACTTen-eleven translocation 1 (TET1) is a member of the DNA demethylase family that regulates the methylation level of the genome. Dysregulation of TET1 in renal cell carcinoma (RCC) may be associated with RCC progression, but the mechanism of TET1 down-regulation in RCC is not yet known. MiR-183-5p is up-regulated in various tumor tissues and acts as an oncogene. We used Transwell and wound healing assays to test cell invasion and migration. To investigate DNA methylation, we used dot blot, which indicates TET1 enzyme activ...
Source: International Journal of Immunopathology and Pharmacology - August 16, 2023 Category: Allergy & Immunology Authors: Shengnan Jin Lu Chen Jiayi Wu Mengjiao Chen Hua Wang Haihong Hu Lushan Yu Su Zeng Source Type: research

MiR-183-5p promotes renal cell carcinoma metastasis by targeting TET1
Int J Immunopathol Pharmacol. 2023 Jan-Dec;37:3946320231184997. doi: 10.1177/03946320231184997.ABSTRACTTen-eleven translocation 1 (TET1) is a member of the DNA demethylase family that regulates the methylation level of the genome. Dysregulation of TET1 in renal cell carcinoma (RCC) may be associated with RCC progression, but the mechanism of TET1 down-regulation in RCC is not yet known. MiR-183-5p is up-regulated in various tumor tissues and acts as an oncogene. We used Transwell and wound healing assays to test cell invasion and migration. To investigate DNA methylation, we used dot blot, which indicates TET1 enzyme activ...
Source: International Journal of Immunopathology and Pharmacology - August 16, 2023 Category: Allergy & Immunology Authors: Shengnan Jin Lu Chen Jiayi Wu Mengjiao Chen Hua Wang Haihong Hu Lushan Yu Su Zeng Source Type: research

Use of canakinumab and remdesivir in moderate-severe COVID-19 patients: A retrospective analysis
Conclusions: Canakinumab and remdesivir treatment, in addition to SOC, in the early stage of moderate-to-severe COVID-19 showed promising outcomes in terms of safety and effectiveness potentially leading to a reduction in inflammatory and hematological prognostic markers after 7 days of treatment.PMID:37534444 | PMC:PMC10402280 | DOI:10.1177/03946320231189993 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - August 3, 2023 Category: Allergy & Immunology Authors: Antonio Mastroianni Valeria Vangeli Luciana Chidichimo Filippo Urso Giuseppe De Marco Alfredo Zanolini Francesca Greco Maria V Mauro Sonia Greco Source Type: research