Impact of IL-10 gene promoter polymorphisms on treatment response in HCV patients: A systematic review, a meta-analysis, and a meta-regression
Int J Immunopathol Pharmacol. 2024 Jan-Dec;38:3946320241240705. doi: 10.1177/03946320241240705.ABSTRACTThe impact of interleukin-10 (IL-10) gene promoter polymorphisms (SNPs) on treatment response in HCV patients was dissimilarly estimated. Hence, the aim of this meta-analysis was to robustly assess the effect of IL-10 SNPs on treatment response in HCV patients. An electronic literature search was carried out through PubMed, EMBASE, Web of science, and Scopus databases. Studies assessing the association between IL-10 polymorphisms and treatment response in HCV patients were included. Studies were excluded if genotype frequ...
Source: International Journal of Immunopathology and Pharmacology - March 23, 2024 Category: Allergy & Immunology Authors: Tarak Dhaouadi Awatef Riahi Ta ïeb Ben Abdallah Yousr Gorgi Imen Sfar Source Type: research

Immunogenicity and adverse events of the COVID-19 vaccines in healthy and individuals with autoimmune diseases in an Iranian population
Conclusion: Our findings revealed that the Sinopharm and Oxford-AstraZeneca vaccines are effective in the production of neutralizing antibodies in healthy subjects and patients with autoimmune disorders undergoing immunosuppressive therapies without considerable reactogenicity.PMID:38494849 | PMC:PMC10946076 | DOI:10.1177/03946320241239202 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - March 18, 2024 Category: Allergy & Immunology Authors: Amin Moradi Hasan-Abad Mohsen Arbabi Hamidreza Gilasi Hossein Motedayyen Source Type: research

Sestrin 2 protects human lens epithelial cells from oxidative stress and apoptosis induced by hydrogen peroxide by regulating the mTOR/Nrf2 pathway
CONCLUSION: SESN2 protected HLECs damage induced by H2O2, which was related to the activation of mTOR/Nrf2 pathway.PMID:38379215 | PMC:PMC10880533 | DOI:10.1177/03946320241234741 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - February 21, 2024 Category: Allergy & Immunology Authors: Xiao Tian Jie Wei Source Type: research