BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells < em > via < /em > regulating the lipoxygenase pathway
Conclusion: Our results suggest that BML-111 may be a potential therapeutic drug for breast cancer and that blocking the 5-LOX pathway could be a possible approach for mining effective drug targets.PMID:38134963 | PMC:PMC10748613 | DOI:10.1177/03946320231223826 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Fen Xu Xiaoyan Zhou Lan Lin Jing Xu Yu Feng Yuanqiao He Hua Hao Source Type: research

Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research

Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice
Conclusions: Our findings suggest that SCL improves diabetes-induced liver injury by alleviating the NF-κB/NLRP3-mediated inflammation and lipid metabolism disorder.PMID:38131326 | PMC:PMC10748632 | DOI:10.1177/03946320231223644 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Leilei Tang Xuan Mei Mengling Ye Yang Liu Yujie Huang Jiawen Yu Lingdi Zhang Sheng Zhuge Guojun Jiang Jianjun Zhu Source Type: research

BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells < em > via < /em > regulating the lipoxygenase pathway
Conclusion: Our results suggest that BML-111 may be a potential therapeutic drug for breast cancer and that blocking the 5-LOX pathway could be a possible approach for mining effective drug targets.PMID:38134963 | PMC:PMC10748613 | DOI:10.1177/03946320231223826 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Fen Xu Xiaoyan Zhou Lan Lin Jing Xu Yu Feng Yuanqiao He Hua Hao Source Type: research

Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research

Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice
Conclusions: Our findings suggest that SCL improves diabetes-induced liver injury by alleviating the NF-κB/NLRP3-mediated inflammation and lipid metabolism disorder.PMID:38131326 | PMC:PMC10748632 | DOI:10.1177/03946320231223644 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Leilei Tang Xuan Mei Mengling Ye Yang Liu Yujie Huang Jiawen Yu Lingdi Zhang Sheng Zhuge Guojun Jiang Jianjun Zhu Source Type: research

BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells < em > via < /em > regulating the lipoxygenase pathway
Conclusion: Our results suggest that BML-111 may be a potential therapeutic drug for breast cancer and that blocking the 5-LOX pathway could be a possible approach for mining effective drug targets.PMID:38134963 | PMC:PMC10748613 | DOI:10.1177/03946320231223826 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Fen Xu Xiaoyan Zhou Lan Lin Jing Xu Yu Feng Yuanqiao He Hua Hao Source Type: research

Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research

Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice
Conclusions: Our findings suggest that SCL improves diabetes-induced liver injury by alleviating the NF-κB/NLRP3-mediated inflammation and lipid metabolism disorder.PMID:38131326 | PMC:PMC10748632 | DOI:10.1177/03946320231223644 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Leilei Tang Xuan Mei Mengling Ye Yang Liu Yujie Huang Jiawen Yu Lingdi Zhang Sheng Zhuge Guojun Jiang Jianjun Zhu Source Type: research

BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells < em > via < /em > regulating the lipoxygenase pathway
Conclusion: Our results suggest that BML-111 may be a potential therapeutic drug for breast cancer and that blocking the 5-LOX pathway could be a possible approach for mining effective drug targets.PMID:38134963 | PMC:PMC10748613 | DOI:10.1177/03946320231223826 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Fen Xu Xiaoyan Zhou Lan Lin Jing Xu Yu Feng Yuanqiao He Hua Hao Source Type: research

Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research

Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice
Conclusions: Our findings suggest that SCL improves diabetes-induced liver injury by alleviating the NF-κB/NLRP3-mediated inflammation and lipid metabolism disorder.PMID:38131326 | PMC:PMC10748632 | DOI:10.1177/03946320231223644 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Leilei Tang Xuan Mei Mengling Ye Yang Liu Yujie Huang Jiawen Yu Lingdi Zhang Sheng Zhuge Guojun Jiang Jianjun Zhu Source Type: research

BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells < em > via < /em > regulating the lipoxygenase pathway
Conclusion: Our results suggest that BML-111 may be a potential therapeutic drug for breast cancer and that blocking the 5-LOX pathway could be a possible approach for mining effective drug targets.PMID:38134963 | PMC:PMC10748613 | DOI:10.1177/03946320231223826 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Fen Xu Xiaoyan Zhou Lan Lin Jing Xu Yu Feng Yuanqiao He Hua Hao Source Type: research

Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research

Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice
Conclusions: Our findings suggest that SCL improves diabetes-induced liver injury by alleviating the NF-κB/NLRP3-mediated inflammation and lipid metabolism disorder.PMID:38131326 | PMC:PMC10748632 | DOI:10.1177/03946320231223644 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Leilei Tang Xuan Mei Mengling Ye Yang Liu Yujie Huang Jiawen Yu Lingdi Zhang Sheng Zhuge Guojun Jiang Jianjun Zhu Source Type: research