International Journal of Immunopathology and Pharmacology 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.3-N-butylphthalide attenuates neuroinflammation in rotenone-induced Parkinson's disease models via the cGAS-STING pathway
This study provided insights for the potential role of NBP in PD therapy, potentially mitigating neurodegeneration, and consequently improving the quality of life and lifespan of patients with PD. The limitations are that we have not confirmed the exact mechanism by which NBP decreases mtDNA leakage, and this study was unable to observe the actual clinical therapeutic effect, so further cohort studies are required for validation.PMID:38315064 | PMC:PMC10846052 | DOI:10.1177/03946320241229041 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - February 5, 2024 Category: Allergy & Immunology Authors: Yuqian Liu Ruonan Duan Peizheng Li Bohan Zhang Yiming Liu Source Type: research
Proposal of pharmacophore model for HIV reverse transcriptase inhibitors: Combined mutational effect analysis, molecular dynamics, molecular docking and pharmacophore modeling study
CONCLUSION: This study underscores the significance of EFV analogs as potential inhibitors of HIV reverse transcriptase. The findings highlight the impact of mutations on drug efficacy, particularly the detrimental effect of G190E. The generated pharmacophore model serves as a pivotal reference for future drug development efforts targeting HIV, providing essential structural insights for the design of potent inhibitors based on EFV analogs identified in vitro.PMID:38296818 | PMC:PMC10832406 | DOI:10.1177/03946320241231465 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 31, 2024 Category: Allergy & Immunology Authors: Azzeddine Annan Noureddine Raiss Sanae Lemrabet Nezha Elomari El Harti Elmir Abdelkarim Filali-Maltouf Leila Medraoui Hicham Oumzil Source Type: research
Corrigendum to "Bibliometric and visual analyses of trends in the field of T cell exhaustion research: Findings from 2000 to 2022"
Int J Immunopathol Pharmacol. 2024 Jan-Dec;38:3946320241226506. doi: 10.1177/03946320241226506.NO ABSTRACTPMID:38247225 | PMC:PMC10804896 | DOI:10.1177/03946320241226506 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 22, 2024 Category: Allergy & Immunology Source Type: research
Activating transcription factor 3 is a new biomarker correlation with renal clear cell carcinoma progression
Conclusions: Our in silico findings highlighted that ATF3 expression was low in ccRCC and negatively correlated with poor prognosis. Furthermore, PAXIP1-AS2 and the OIP5-AS1/hsa-miR-221-3p/ATF3 axis were identified as significant potential regulators of ER stress-mediated apoptosis in ccRCC.PMID:38248871 | PMC:PMC10804930 | DOI:10.1177/03946320241227320 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 22, 2024 Category: Allergy & Immunology Authors: Zhicong Yang Yongwang Hou Jingqi Li Dandan Xu Zhichao Yang Xinsheng Wang Source Type: research
CXC ligand 13 orchestrates an immunoactive microenvironment and enhances immunotherapy response in head and neck squamous cell carcinoma
Conclusions: CXCL13 may function as a potential biomarker for predicting prognosis and immunotherapy response and associate with TLSs in HNSCC.PMID:38252495 | PMC:PMC10807398 | DOI:10.1177/03946320241227312 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 22, 2024 Category: Allergy & Immunology Authors: Xiaohu Lin Xiaomei Zhao Yiming Chen Rong Yang Zhenlin Dai Wei Li Chengzhong Lin Wei Cao Source Type: research
Antidiabetic and antioxidant potential of Crocin in high-fat diet plus streptozotocin-induced type-2 diabetic rats
CONCLUSION: The overall finding indicates that intraperitoneal administration of Crocin demonstrated better control of glycemic level and body weight. Further, it has improved insulin levels in the serum and potentiated antioxidant properties.PMID:38233742 | PMC:PMC10798082 | DOI:10.1177/03946320231220178 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 17, 2024 Category: Allergy & Immunology Authors: Syed Mohammed Basheeruddin Asdaq Basheerahmed Abdulaziz Mannasaheb Raha Orfali Ibrahim Ahmed Shaikh Ahmed Alshehri Adel Alghamdi Meshal Mohammed Alrashdi Moneer E Almadani Faisal Mohammad Ali Abdalla Source Type: research
The use of inhibition assay in Api g 7 suspected allergy in a female patient with anaphylaxis: A case report
In conclusion, Api g 7 is an important celery allergen that can be responsible for severe reactions. Its cross-reactivity with Art v 1 is characteristic. Negative diagnostic tests with celery do not exclude Api g 7 sensitization.PMID:38217433 | PMC:PMC10788074 | DOI:10.1177/03946320231223004 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 13, 2024 Category: Allergy & Immunology Authors: Natalia Ukleja-Soko łowska Kinga Lis Ma łgorzata Graczyk Marcelina Bartuzi Zbigniew Bartuzi Source Type: research
The hepatotoxicity of γ-radiation synthesized 5-fluorouracil nanogel versus 5-fluorouracil in rats model
CONCLUSION: Consequently, 5-Fu nanogel exhibited lower liver toxicity compared to 5-FU, likely due to the alleviation of hepatic inflammation and the regulation of the cellular redox pathway.PMID:38207276 | PMC:PMC10785744 | DOI:10.1177/03946320241227099 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - January 11, 2024 Category: Allergy & Immunology Authors: Wael Em Barakat Fatma Sm Moawed Esraa Sa Ahmed Omayma Ar Abo-Zaid Source Type: research
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research
Sclareol ameliorates liver injury by inhibiting nuclear factor-kappa B/NOD-like receptor protein 3-mediated inflammation and lipid metabolism disorder in diabetic mice
Conclusions: Our findings suggest that SCL improves diabetes-induced liver injury by alleviating the NF-κB/NLRP3-mediated inflammation and lipid metabolism disorder.PMID:38131326 | PMC:PMC10748632 | DOI:10.1177/03946320231223644 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Leilei Tang Xuan Mei Mengling Ye Yang Liu Yujie Huang Jiawen Yu Lingdi Zhang Sheng Zhuge Guojun Jiang Jianjun Zhu Source Type: research
BML-111, the agonist of lipoxin A4, suppresses epithelial-mesenchymal transition and migration of MCF-7 cells < em > via < /em > regulating the lipoxygenase pathway
Conclusion: Our results suggest that BML-111 may be a potential therapeutic drug for breast cancer and that blocking the 5-LOX pathway could be a possible approach for mining effective drug targets.PMID:38134963 | PMC:PMC10748613 | DOI:10.1177/03946320231223826 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Fen Xu Xiaoyan Zhou Lan Lin Jing Xu Yu Feng Yuanqiao He Hua Hao Source Type: research
Cancer susceptibility 18 positively regulates NUAK Family Kinase 1 expression to promote migration and invasion via sponging of miR-5586-5p in cervical cancer cells
CONCLUSION: Our study showed a novel CASC18/miR-5586-5p/NUAK1 ceRNA axis that could regulate cell invasion and migration by modulating EMT in CESC. These findings suggest that CASC18 may potentially serve as a novel therapeutic target in CESC treatment.PMID:38131232 | PMC:PMC10748670 | DOI:10.1177/03946320231223310 (Source: International Journal of Immunopathology and Pharmacology)
Source: International Journal of Immunopathology and Pharmacology - December 22, 2023 Category: Allergy & Immunology Authors: Jingrong Wang Bocheng Zhang Sha Gong Ying Liu Liang Yi Ying Long Source Type: research
