Revolutionizing antiretroviral therapy for human immunodeficiency virus/AIDS: A computational approach using molecular docking, virtual screening, and 3D pharmacophore building to address therapeutic failure and propose highly effective candidates

CONCLUSION: The combination of molecular docking, virtual screening, and 3D pharmacophore modeling yielded lead compounds that hold potential for addressing HIV therapeutic failures. Further experimental investigations are essential to validate the efficacy and safety of these compounds, with the ultimate goal of advancing toward clinical applications in HIV management.PMID:37850462 | DOI:10.1177/03946320231207514

Source: International Journal of Immunopathology and Pharmacology - October 18, 2023 Category: Allergy & Immunology Authors: Azzeddine Annan Noureddine Raiss El Harti Elmir Abdelkarim Filali-Maltouf Leila Medraoui Hicham Oumzil Source Type: research