International Journal of Clinical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Clinical implications of inaccurate potassium determination in hemolyzed pediatric blood specimens
CONCLUSIONS: The use of whole blood analysis brings with it significant risk for error in potassium measurement. Better tools to detect hemolysis in these types of specimens are indicated.PMID:38460583 | DOI:10.1016/j.cca.2024.117862 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - March 9, 2024 Category: Chemistry Authors: Dennis J Dietzen Ronald Jackups Mark A Zaydmanon Source Type: research

Breast cancer stem cells as novel biomarkers
Clin Chim Acta. 2024 Mar 5:117855. doi: 10.1016/j.cca.2024.117855. Online ahead of print.ABSTRACTBreast cancer is the most common cancer and the leading cause of mortality worldwide. Despite advancements in detection and treatment, it remains a major cause of cancer-related deaths in women. Breast cancer stem cells (BCSCs) are a crucial group of cells responsible for carcinogenesis, metastasis, medication resistance, and tumor recurrence. Identifying and understanding their molecular pathways is essential for developing effective breast cancer therapy. BCSCs are responsible for tumor genesis, development, metastasis, treat...
Source: International Journal of Clinical Chemistry - March 7, 2024 Category: Chemistry Authors: Suman Kumar Ray Sukhes Mukherjee Source Type: research

Machine learning reveals serum myristic acid, palmitic acid and heptanoylcarnitine as biomarkers of coronary artery disease risk in patients with type 2 diabetes mellitus
CONCLUSION: Altogether, these findings suggest that myristic acid, palmitic acid and heptanoylcarnitine have a good prospect for the warning of CHD complications in T2DM patients, and are superior to traditional lipid, blood glucose and blood pressure indicators.PMID:38438006 | DOI:10.1016/j.cca.2024.117852 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - March 4, 2024 Category: Chemistry Authors: Ting Hu Wen Zhang Feifei Han Rui Zhao Hongchuan Liu Zhuoling An Source Type: research

Globotriaosylsphingosine improves risk stratification of kidney progression in Fabry disease patients
CONCLUSIONS: Lyso-Gb3 improves the prediction of kidney outcomes in FD patients with a low risk of progression, suggesting that these patients may benefit from early intervention to assist in clinical management. These findings need to be externally validated.PMID:38438007 | DOI:10.1016/j.cca.2024.117851 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - March 4, 2024 Category: Chemistry Authors: Yan Ouyang Wei Zhang Zhanzheng Zhao Chaohui Wang Hong Ren Jingyuan Xie Xiao Li Pingyan Shen Hao Shi Jing Xu Yaowen Xu Weiming Wang Li Yang Xialian Yu Weihong Chen YaWen Zhao Zheng Wang YiFan Wu Nan Chen XiaoXia Pan Source Type: research

Metabolomics of male infertility
Clin Chim Acta. 2024 Feb 29:117850. doi: 10.1016/j.cca.2024.117850. Online ahead of print.ABSTRACTThis review explores the use of metabolomics in male infertility. Metabolomics, an evolving omics technology that targets the products of cellular metabolism, is valuable for elucidating underlying pathophysiology of many disorders including male infertility. The identification of reliable biomarkers is essential for accurate diagnosis and for developing precision therapeutics for those afflicted by reproductive dysfunction. Unfortunately, despite significant progress to date, the intricate relationships between these metaboli...
Source: International Journal of Clinical Chemistry - March 2, 2024 Category: Chemistry Authors: Amos Victor Oluwaloseyi Odeyemi Aduragbemi Noah Ajayi Lydia Oluwatoyin Yusuff Gaffar Olotu Moses Akano Oyedayo Phillips Moyinoluwa Comfort Onaolapo Bolade Sylvester Olateju Adelakun Ademola Ayodele Oyowvi Mega Obukohwo Ajayi Ayodeji Folorunsho Source Type: research

Rapid serum tubes reduce transport hemolysis and false positive rates for high-sensitivity troponin T
CONCLUSION: We suggest that proper tube filling during sample collection and use of RST tubes can significantly reduce the effects of hemolysis. In addition, laboratories should be aware that PST tubes have a non-trivial rate of false positives when hs-cTnT < 50 ng/l.PMID:38420909 | DOI:10.1016/j.cca.2023.117630 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - February 29, 2024 Category: Chemistry Authors: Hind Malaeb Michael A Vera Rohit B Sangal Arjun K Venkatesh Stephen Possick Lisa Maciejak Erica Oberle Joe M El-Khoury Source Type: research

Corrigendum to "Diagnosis of invasive non-functional pituitary adenomas using exosomal biomarkers" [Clinica Chimica Acta. 529 (2022) 25-33/(PMID: 35085587)]
Clin Chim Acta. 2024 Feb 28:117846. doi: 10.1016/j.cca.2024.117846. Online ahead of print.NO ABSTRACTPMID:38423932 | DOI:10.1016/j.cca.2024.117846 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - February 29, 2024 Category: Chemistry Authors: Yuan Ren Ying Wang Xinjie Bao Ming Feng Bing Xing Wei Lian Yong Yao Renzhi Wang Source Type: research