International Journal of Clinical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

HDL subfractions determined by microfluidic chip electrophoresis predict the vulnerability of intracranial plaque: A HRMRI study
CONCLUSIONS: Our data showed that serum HDL-2b levels may serve as a biomarker for predicting vulnerability in intracranial atherosclerotic plaques.PMID:38104956 | DOI:10.1016/j.cca.2023.117713 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - December 17, 2023 Category: Chemistry Authors: Deng Zhezhi Zheng Zhihui Zhang Shifeng Li Minping Xu Xue Qi Weiwei Guo Junjie Zhou Dongxiao Ma Qian Qiu Yuemin David Xingfei Deng Huang Haiwei Source Type: research

Thrombin generation and all-cause mortality in the brazilian longitudinal study of adult health (ELSA-Brasil)
CONCLUSIONS: Delayed thrombin generation was associated with higher risk of all-cause mortality.PMID:38103851 | DOI:10.1016/j.cca.2023.117712 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - December 16, 2023 Category: Chemistry Authors: Let ícia Gonçalves Resende Ferreira Sandhi Maria Barreto Chams Bicalho Maluf Ant ônio Luiz Pinho Ribeiro Maria das Gra ças Carvalho Roberta Carvalho Figueiredo Danyelle Romana Alves Rios Source Type: research

An ultra performance liquid chromatography method for transthyretin variants screening and heart failure assisting diagnosis
CONCLUSIONS: UPLC method has sufficient accuracy to eliminate the necessity of sequencing for certain types of TTR mutations and allows for facile initial screening of ATTR amyloidosis patients, carriers, and healthy individuals for time-saving and economical purposes. TTR tetramer may serve as a diagnostic biomarker to evaluate the risk of HF diseases.PMID:38103852 | DOI:10.1016/j.cca.2023.117709 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - December 16, 2023 Category: Chemistry Authors: Shuang Wang Liping Guan Yang Sun Li Cui Shigang Guo Mengdie Wang Yu Liu Xueting Cui Furong Zhao Yanjie Zhang Yunfeng Cao Source Type: research

Detection of lenalidomide metabolites in urine to discover drug-resistant compounds
Clin Chim Acta. 2023 Dec 14:117707. doi: 10.1016/j.cca.2023.117707. Online ahead of print.ABSTRACTLenalidomide is the first-line drug for the clinical treatment of multiple myeloma. However, its efficacy differs significantly among patients. Clinically, after lenalidomide treatment, few patients' conditions worsened, whereas others remained stable or improved. To clarify the reasons for this difference in efficacy, 20 patients with multiple myeloma who received maintenance treatment with lenalidomide were retrospectively included in this study. Lenalidomide metabolic compounds were detected in patient urine using mass spec...
Source: International Journal of Clinical Chemistry - December 16, 2023 Category: Chemistry Authors: Xiaokai Zhan Xikun Liu Li Rang Man Shen Jiajia Zhang Ran Tang Sibin Fan Fengyi Zhao Xin Li Xiaoying Zhang Zhongxia Huang Sen Zhang Source Type: research

Interference against a newly labeled substance with ruthenium sulfonate complexes showing discrepant thyroid function test results
We report here two patients exhibiting a combination of falsely elevated serum levels of free thyroxine (FT4), free triiodothyronine (FT3), and thyrotropin receptor antibodies (TRAb), measured using Elecsys assay kits (Roche Diagnostics GmbH). The first patient was a 74-year-old man misdiagnosed with Graves' disease and treated with methimazole. The second patient was a 48-year-old woman whose serum FT4 and FT3 concentrations were found to be high during a blood test. These patients denied taking biotin or any other supplements. Further detailed examination, including a heterophilic blocking tube test, revealed the presenc...
Source: International Journal of Clinical Chemistry - December 15, 2023 Category: Chemistry Authors: Sawako Takahashi Mitsushige Nishikawa Eijun Nishihara Hanna Deguchi Kazuyoshi Kohsaka Hiroyuki Yamaoka Mako Hisakado Shuji Fukata Mitsuru Ito Akira Miyauchi Takashi Akamizu Source Type: research