International Journal of Clinical Chemistry This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Molecular diagnosis is an important indicator for response to growth hormone therapy in children with short stature
CONCLUSIONS: This study highlights the utility of WES in identifying genetic etiology in children with short stature. Identifying likely causal mutations is an important factor in predicting rhGH response.PMID:38220134 | DOI:10.1016/j.cca.2024.117779 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 14, 2024 Category: Chemistry Authors: Qianqian Zhao Mei Zhang Yanying Li Chuanpeng Zhang Yanhong Zhang Qian Shao Wei Wei Wanling Yang Bo Ban Source Type: research

The association between plasma angiopoietin-like protein 4, glucose and lipid metabolism during pregnancy, placental function, and risk of delivering large-for-gestational-age neonates
CONCLUSIONS: Plasma ANGPTL4 is associated with glucose and lipid metabolism during pregnancy, plasma GH-V, and birth weight, and is an early biomarker for predicting the risk of LGA.PMID:38220135 | DOI:10.1016/j.cca.2024.117775 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 14, 2024 Category: Chemistry Authors: I-Weng Yen Shin-Yu Lin Ming-Wei Lin Chien-Nan Lee Chun-Heng Kuo Szu-Chieh Chen Yi-Yun Tai Ching-Hua Kuo Han-Chun Kuo Heng-Huei Lin Hsien-Chia Juan Chia-Hung Lin Kang-Chih Fan Chih-Yuan Wang Hung-Yuan Li Source Type: research

Correction of creatine-creatinine conversion during serum creatinine quantification by two-dimensional liquid chromatography and double-spike isotope dilution tandem mass spectrometry
CONCLUSIONS: The method provides adequate analytical figures of merit for serum creatinine determination according to CSLI guidelines. Negligible creatine-creatinine interconversion is promoted with the applied sample preparation procedure.PMID:38220136 | DOI:10.1016/j.cca.2024.117778 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 14, 2024 Category: Chemistry Authors: Daniela Pineda-Cevallos Mar ía Funes Menéndez Adriana Gonz ález-Gago Pablo Rodr íguez-González J Ignacio Garc ía Alonso Source Type: research

Exploring optimization algorithms for establishing patient-based real-time quality control models
CONCLUSION: More efficient optimization methods should be adopted when establishing PBRTQC or RARTQC models to save time and computing power that will enable the development of more complex models and increase the scalability of extensive PBRTQC applications.PMID:38220137 | DOI:10.1016/j.cca.2024.117774 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 14, 2024 Category: Chemistry Authors: Xincen Duan Chunyan Zhang Xiao Tan Baishen Pan Wei Guo Beili Wang Source Type: research

Altered bile metabolome and its diagnostic potential for biliopancreatic malignancies
CONCLUSIONS: This study found metabolic alterations in biliopancreatic malignancies based on bile samples, which may provide new insights for the clinical diagnosis and prognostic assessment of biliopancreatic malignancies.PMID:38220138 | DOI:10.1016/j.cca.2024.117777 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 14, 2024 Category: Chemistry Authors: Fusheng Liu Yingyi Liu Xingyuan Hao Bin Liu Xuyun Yan Anling Li Ping Jiang Weihua Huang Song-Mei Liu Yufeng Yuan Source Type: research

The role of irisin in kidney diseases
Clin Chim Acta. 2024 Feb 1;554:117756. doi: 10.1016/j.cca.2023.117756. Epub 2024 Jan 12.ABSTRACTIrisin is a hormone that is produced mainly by skeletal muscles in response to exercise. It has been found to have a close correlation with obesity and diabetes mellitus for its energy expenditure and metabolic properties. Recent research has revealed that irisin also possesses anti-inflammatory, anti-oxidative and anti-apoptotic properties, which make it associated with major chronic diseases, such as chronic kidney disease (CKD), liver diseases, osteoporosis, atherosclerosis and Alzheimer s disease. The identification of irisi...
Source: International Journal of Clinical Chemistry - January 13, 2024 Category: Chemistry Authors: Xiejia Li Bengt Lindholm Source Type: research

Machine learning in the prediction of in-hospital mortality in patients with first acute myocardial infarction
CONCLUSION: In order to improve the forecasting accuracy of the risk of AMI patients, guide clinical nursing practice, and lower AMI inpatient mortality, this study looked into significant indicators and the optimal models for predicting AMI inpatient mortality.PMID:38216028 | DOI:10.1016/j.cca.2024.117776 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 12, 2024 Category: Chemistry Authors: Xiaoli Zhu Bojian Xie Yijun Chen Hanqian Zeng Jinxi Hu Source Type: research

Accurate correction model of blood potassium concentration in hemolytic specimens
CONCLUSIONS: Both linear regression and curve fitting models of potassium correction had high accuracy, and can effectively correct the potassium concentration of hemolytic specimens, while the curve fitting model have superior accuracy.PMID:38211807 | DOI:10.1016/j.cca.2024.117762 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 11, 2024 Category: Chemistry Authors: Mulatijiang Maimaiti Boxin Yang Tong Xu Liyan Cui Shuo Yang Source Type: research

Exosomal miRNAs from neutrophils act as accurate biomarkers for gastric cancer diagnosis
CONCLUSION: The Dynabeads-based separation and detection system, assisted with ddPCR analysis, provides a promising platform to enrich Neu-Exo and analyze miRNA profile for gastric cancer liquid biopsy.PMID:38199579 | DOI:10.1016/j.cca.2024.117773 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 10, 2024 Category: Chemistry Authors: Dan Yu Jiahui Zhang Maoye Wang Runbi Ji Hui Qian Wenrong Xu Hongbo Zhang Jianmei Gu Xu Zhang Source Type: research

Anti-phosphatidyl-serine/prothrombin (aPS/PT) antibodies are superior predictors of LAC presence and APS diagnoses: A single Center Study
CONCLUSION: Anti-phosphatidyl-serine/prothrombin (aPS/PT) antibodies are superior predictors of LAC presence and APS diagnoses.PMID:38195020 | DOI:10.1016/j.cca.2024.117761 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 9, 2024 Category: Chemistry Authors: Abdulrahman Saadalla Vijayalakshmi Nandakumar Source Type: research

Evaluation of insulin secretion and insulin sensitivity in pregnant women: Application value of simple indices
This article reviews the progress in the application of simple indices to help clinicians better understand their potential application in detecting GDM.PMID:38185282 | DOI:10.1016/j.cca.2023.117753 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 7, 2024 Category: Chemistry Authors: Shuying Ren Dan Wu Ping Li Source Type: research

Pseudo-targeted Metabolic Profile Differences between Emergency Patients with Type 1 and Type 2 Myocardial Infarction Diagnosed by Optical Coherence Tomography
CONCLUSIONS: There are significant metabolic profile differences between T1MI and T2MI. Several candidate metabolic biomarkers can effectively distinguish the two groups.PMID:38185283 | DOI:10.1016/j.cca.2023.117745 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 7, 2024 Category: Chemistry Authors: Jifei Wang Zhaoying Li Guang Yang Chao Fang Yanwei Yin Zhilei Zheng Hongwei Wang Shaohong Fang Jiannan Dai Shanjie Wang Shuang Yang Bo Yu Source Type: research

Liquid chromatography-tandem mass spectrometry methods for quantification of total and free antibiotic concentrations in serum and exudate from patients with post-sternotomy deep sternal wound infection receiving negative pressure wound therapy
CONCLUSION: This method can accurately quantify the total and free concentrations of 16 antibiotics. Comparison of concentration ratios between serum and exudates allows for monitoring individual antibiotics' penetration capacity in patients receiving NPWT.PMID:38185284 | DOI:10.1016/j.cca.2023.117704 (Source: International Journal of Clinical Chemistry)
Source: International Journal of Clinical Chemistry - January 7, 2024 Category: Chemistry Authors: Hana Brozmanov á Pavel Šištík Jana Ďuricová Ivana Kac ířová Kl ára Kaňková Martin Kolek Source Type: research