Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 30;115:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. W...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research

Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 30;115:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. W...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research

Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 29:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. We al...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research

Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 29:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. We al...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research

Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 29:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. We al...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research

Full genome-based characterization of an Asian G3P[6] human rotavirus strain found in a diarrheic child in Japan: Evidence for porcine-to-human zoonotic transmission
Infect Genet Evol. 2023 Sep 25;115:105507. doi: 10.1016/j.meegid.2023.105507. Online ahead of print.ABSTRACTHuman rotavirus strains having the unconventional G3P[6] genotype have been sporadically detected in diarrheic patients in different parts of the world. However, the full genomes of only three human G3P[6] strains from Asian countries (China, Indonesia, and Vietnam) have been sequenced and characterized, and thus the exact origin and evolution of G3P[6] strains in Asia remain to be elucidated. Here, we sequenced and characterized the full genome of a G3P[6] strain (RVA/Human-wt/JPN/SO1199/2020/G3P[6]) found in a stoo...
Source: Infection, Genetics and Evolution - September 27, 2023 Category: Genetics & Stem Cells Authors: Yuki Akari Riona Hatazawa Haruo Kuroki Hiroaki Ito Manami Negoro Takaaki Tanaka Haruna Miwa Katsumi Sugiura Masakazu Umemoto Shigeki Tanaka Masahiro Ogawa Mitsue Ito Saori Fukuda Takayuki Murata Kiyosu Taniguchi Shigeru Suga Hajime Kamiya Takashi Nakano K Source Type: research

Spoligotyping of Mycobacterium tuberculosis - Comparing in vitro and in silico approaches
Infect Genet Evol. 2023 Sep 25:105508. doi: 10.1016/j.meegid.2023.105508. Online ahead of print.ABSTRACTSpoligotyping is one of the molecular typing methods widely used for exploring the genetic variety of Mycobacterium tuberculosis. The aim of this study was to compare the spoligoprofiles of M. tuberculosis clinical isolates, obtained using in vitro and in silico approaches. The study included 230 M. tuberculosis isolates, recovered from Poland and Lithuania between 2018 and 2021. Spoligotyping in vitro was performed with a commercially available kit. Whole genome sequencing (WGS) was done with Illumina NovaSeq 6000 seque...
Source: Infection, Genetics and Evolution - September 27, 2023 Category: Genetics & Stem Cells Authors: Zofia Baku ła Miko łaj Dziurzyński Przemys ław Decewicz Daiva Bakonyt ė Laima Vasiliauskait ė Birut ė Nakčerienė Rafa ł Krenke Petras Stak ėnas Tomasz Jagielski Source Type: research

Full genome-based characterization of an Asian G3P[6] human rotavirus strain found in a diarrheic child in Japan: Evidence for porcine-to-human zoonotic transmission
Infect Genet Evol. 2023 Sep 25:105507. doi: 10.1016/j.meegid.2023.105507. Online ahead of print.ABSTRACTHuman rotavirus strains having the unconventional G3P[6] genotype have been sporadically detected in diarrheic patients in different parts of the world. However, the full genomes of only three human G3P[6] strains from Asian countries (China, Indonesia, and Vietnam) have been sequenced and characterized, and thus the exact origin and evolution of G3P[6] strains in Asia remain to be elucidated. Here, we sequenced and characterized the full genome of a G3P[6] strain (RVA/Human-wt/JPN/SO1199/2020/G3P[6]) found in a stool sa...
Source: Infection, Genetics and Evolution - September 27, 2023 Category: Genetics & Stem Cells Authors: Yuki Akari Riona Hatazawa Haruo Kuroki Hiroaki Ito Manami Negoro Takaaki Tanaka Haruna Miwa Katsumi Sugiura Masakazu Umemoto Shigeki Tanaka Masahiro Ogawa Mitsue Ito Saori Fukuda Takayuki Murata Kiyosu Taniguchi Shigeru Suga Hajime Kamiya Takashi Nakano K Source Type: research

Spoligotyping of Mycobacterium tuberculosis - Comparing in vitro and in silico approaches
Infect Genet Evol. 2023 Sep 25:105508. doi: 10.1016/j.meegid.2023.105508. Online ahead of print.ABSTRACTSpoligotyping is one of the molecular typing methods widely used for exploring the genetic variety of Mycobacterium tuberculosis. The aim of this study was to compare the spoligoprofiles of M. tuberculosis clinical isolates, obtained using in vitro and in silico approaches. The study included 230 M. tuberculosis isolates, recovered from Poland and Lithuania between 2018 and 2021. Spoligotyping in vitro was performed with a commercially available kit. Whole genome sequencing (WGS) was done with Illumina NovaSeq 6000 seque...
Source: Infection, Genetics and Evolution - September 27, 2023 Category: Genetics & Stem Cells Authors: Zofia Baku ła Miko łaj Dziurzyński Przemys ław Decewicz Daiva Bakonyt ė Laima Vasiliauskait ė Birut ė Nakčerienė Rafa ł Krenke Petras Stak ėnas Tomasz Jagielski Source Type: research

Full genome-based characterization of an Asian G3P[6] human rotavirus strain found in a diarrheic child in Japan: Evidence for porcine-to-human zoonotic transmission
Infect Genet Evol. 2023 Sep 25:105507. doi: 10.1016/j.meegid.2023.105507. Online ahead of print.ABSTRACTHuman rotavirus strains having the unconventional G3P[6] genotype have been sporadically detected in diarrheic patients in different parts of the world. However, the full genomes of only three human G3P[6] strains from Asian countries (China, Indonesia, and Vietnam) have been sequenced and characterized, and thus the exact origin and evolution of G3P[6] strains in Asia remain to be elucidated. Here, we sequenced and characterized the full genome of a G3P[6] strain (RVA/Human-wt/JPN/SO1199/2020/G3P[6]) found in a stool sa...
Source: Infection, Genetics and Evolution - September 27, 2023 Category: Genetics & Stem Cells Authors: Yuki Akari Riona Hatazawa Haruo Kuroki Hiroaki Ito Manami Negoro Takaaki Tanaka Haruna Miwa Katsumi Sugiura Masakazu Umemoto Shigeki Tanaka Masahiro Ogawa Mitsue Ito Saori Fukuda Takayuki Murata Kiyosu Taniguchi Shigeru Suga Hajime Kamiya Takashi Nakano K Source Type: research

Spoligotyping of Mycobacterium tuberculosis - Comparing in vitro and in silico approaches
Infect Genet Evol. 2023 Sep 25:105508. doi: 10.1016/j.meegid.2023.105508. Online ahead of print.ABSTRACTSpoligotyping is one of the molecular typing methods widely used for exploring the genetic variety of Mycobacterium tuberculosis. The aim of this study was to compare the spoligoprofiles of M. tuberculosis clinical isolates, obtained using in vitro and in silico approaches. The study included 230 M. tuberculosis isolates, recovered from Poland and Lithuania between 2018 and 2021. Spoligotyping in vitro was performed with a commercially available kit. Whole genome sequencing (WGS) was done with Illumina NovaSeq 6000 seque...
Source: Infection, Genetics and Evolution - September 27, 2023 Category: Genetics & Stem Cells Authors: Zofia Baku ła Miko łaj Dziurzyński Przemys ław Decewicz Daiva Bakonyt ė Laima Vasiliauskait ė Birut ė Nakčerienė Rafa ł Krenke Petras Stak ėnas Tomasz Jagielski Source Type: research

RNA Polymerase II evolution and adaptations: Insights from Plasmodium and other parasitic protists
In this study, we performed a comparative analysis of CTD in eukaryotic systems to understand why the parasites evolved in this particular manner. The Plasmodium falciparum RPB1 is exceptionally large and feature a gap between the first and second heptad repeats, resulting in fifteen canonical heptad repeats excluding the initial repeat. Analysis of this intervening sequence revealed sub motifs of heptads where two serine residues occupy the first and fourth positions (S1X2X3S4). These motifs lie in the intrinsically disordered region of RPB1, a characteristic feature of the CTD. Interestingly, the S1X2X3S4 sub-motif was a...
Source: Infection, Genetics and Evolution - September 25, 2023 Category: Genetics & Stem Cells Authors: Devatrisha Purkayastha Krishanpal Karmodiya Source Type: research

RNA Polymerase II evolution and adaptations: Insights from Plasmodium and other parasitic protists
In this study, we performed a comparative analysis of CTD in eukaryotic systems to understand why the parasites evolved in this particular manner. The Plasmodium falciparum RPB1 is exceptionally large and feature a gap between the first and second heptad repeats, resulting in fifteen canonical heptad repeats excluding the initial repeat. Analysis of this intervening sequence revealed sub motifs of heptads where two serine residues occupy the first and fourth positions (S1X2X3S4). These motifs lie in the intrinsically disordered region of RPB1, a characteristic feature of the CTD. Interestingly, the S1X2X3S4 sub-motif was a...
Source: Infection, Genetics and Evolution - September 25, 2023 Category: Genetics & Stem Cells Authors: Devatrisha Purkayastha Krishanpal Karmodiya Source Type: research

RNA Polymerase II evolution and adaptations: Insights from Plasmodium and other parasitic protists
In this study, we performed a comparative analysis of CTD in eukaryotic systems to understand why the parasites evolved in this particular manner. The Plasmodium falciparum RPB1 is exceptionally large and feature a gap between the first and second heptad repeats, resulting in fifteen canonical heptad repeats excluding the initial repeat. Analysis of this intervening sequence revealed sub motifs of heptads where two serine residues occupy the first and fourth positions (S1X2X3S4). These motifs lie in the intrinsically disordered region of RPB1, a characteristic feature of the CTD. Interestingly, the S1X2X3S4 sub-motif was a...
Source: Infection, Genetics and Evolution - September 25, 2023 Category: Genetics & Stem Cells Authors: Devatrisha Purkayastha Krishanpal Karmodiya Source Type: research

Molecular evidence of Rickettsia canadensis in ticks, Hebei, China
In this study, parasitic and questing ticks were recovered from two sampling sites in Hebei, China. Specific primers targeting outer membrane protein B (ompB) gene were designed to test the presence of Rickettsia canadensis by nested Polymerase Chain Reaction (PCR). As a result, a total of 428 ticks, including 232 ticks (including 230 Haemaphysalis longicornis and two H. japonica) from Laiyuan County and 196 (H. longicornis) from Luanping County, were collected. Sequencing of PCR products with the expected size and subsequently BLAST showed that 38H. longicornis ticks tested positive for R. canadensis, with an overall posi...
Source: Infection, Genetics and Evolution - September 24, 2023 Category: Genetics & Stem Cells Authors: Jing Xue Si-Si Chen Rui Jian Guo-Qing Chen Guangcheng Xie Luanying Du Wen-Ping Guo Source Type: research