Highly diverse dynamics of Pseudomonas aeruginosa colonization from initial detection in cystic fibrosis patients: A 7-year longitudinal genetic diversity study
Infect Genet Evol. 2023 Oct 11:105513. doi: 10.1016/j.meegid.2023.105513. Online ahead of print.ABSTRACTIn cystic fibrosis (CF), Pseudomonas aeruginosa (Pa) is a major pathogen that can persistently colonize patients. Genetic studies showed a high diversity of Pa, the success of widespread or 'international' clones and described epidemic clones in CF and Epidemic High-Risk (ERH) clones. Here, we characterized Pa genetic diversity over time after first colonization in CF patients, with the aim of accurately describing the dynamics of colonization in a context of scarce longitudinal studies. Results represent the first genot...
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Chlo é Dupont Fabien Aujoulat Massilia Benaoudia Estelle Jumas-Bilak Rapha ël Chiron H élène Marchandin Source Type: research
HIV-1 subtypes maintain distinctive physicochemical signatures in Nef domains associated with immunoregulation
CONCLUSIONS: Recent studies have focused on HIV Nef as a driver of immunoregulatory disease in those HIV infected and on ART. Nef acts through a complex mixture of interactions that are directly linked to the key features of the subtype-specific domains we identified with the ENN. The study supports the hypothesis that varied Nef subtypes contribute to subtype-specific disease progression.PMID:37832752 | DOI:10.1016/j.meegid.2023.105514 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Susanna L Lamers Gary B Fogel Enoch S Liu David J Nolan Rebecca Rose Michael S McGrath Source Type: research
Highly diverse dynamics of Pseudomonas aeruginosa colonization from initial detection in cystic fibrosis patients: A 7-year longitudinal genetic diversity study
Infect Genet Evol. 2023 Oct 11:105513. doi: 10.1016/j.meegid.2023.105513. Online ahead of print.ABSTRACTIn cystic fibrosis (CF), Pseudomonas aeruginosa (Pa) is a major pathogen that can persistently colonize patients. Genetic studies showed a high diversity of Pa, the success of widespread or 'international' clones and described epidemic clones in CF and Epidemic High-Risk (ERH) clones. Here, we characterized Pa genetic diversity over time after first colonization in CF patients, with the aim of accurately describing the dynamics of colonization in a context of scarce longitudinal studies. Results represent the first genot...
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Chlo é Dupont Fabien Aujoulat Massilia Benaoudia Estelle Jumas-Bilak Rapha ël Chiron H élène Marchandin Source Type: research
HIV-1 subtypes maintain distinctive physicochemical signatures in Nef domains associated with immunoregulation
CONCLUSIONS: Recent studies have focused on HIV Nef as a driver of immunoregulatory disease in those HIV infected and on ART. Nef acts through a complex mixture of interactions that are directly linked to the key features of the subtype-specific domains we identified with the ENN. The study supports the hypothesis that varied Nef subtypes contribute to subtype-specific disease progression.PMID:37832752 | DOI:10.1016/j.meegid.2023.105514 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Susanna L Lamers Gary B Fogel Enoch S Liu David J Nolan Rebecca Rose Michael S McGrath Source Type: research
Highly diverse dynamics of Pseudomonas aeruginosa colonization from initial detection in cystic fibrosis patients: A 7-year longitudinal genetic diversity study
Infect Genet Evol. 2023 Oct 11:105513. doi: 10.1016/j.meegid.2023.105513. Online ahead of print.ABSTRACTIn cystic fibrosis (CF), Pseudomonas aeruginosa (Pa) is a major pathogen that can persistently colonize patients. Genetic studies showed a high diversity of Pa, the success of widespread or 'international' clones and described epidemic clones in CF and Epidemic High-Risk (ERH) clones. Here, we characterized Pa genetic diversity over time after first colonization in CF patients, with the aim of accurately describing the dynamics of colonization in a context of scarce longitudinal studies. Results represent the first genot...
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Chlo é Dupont Fabien Aujoulat Massilia Benaoudia Estelle Jumas-Bilak Rapha ël Chiron H élène Marchandin Source Type: research
HIV-1 subtypes maintain distinctive physicochemical signatures in Nef domains associated with immunoregulation
CONCLUSIONS: Recent studies have focused on HIV Nef as a driver of immunoregulatory disease in those HIV infected and on ART. Nef acts through a complex mixture of interactions that are directly linked to the key features of the subtype-specific domains we identified with the ENN. The study supports the hypothesis that varied Nef subtypes contribute to subtype-specific disease progression.PMID:37832752 | DOI:10.1016/j.meegid.2023.105514 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Susanna L Lamers Gary B Fogel Enoch S Liu David J Nolan Rebecca Rose Michael S McGrath Source Type: research
Highly diverse dynamics of Pseudomonas aeruginosa colonization from initial detection in cystic fibrosis patients: A 7-year longitudinal genetic diversity study
Infect Genet Evol. 2023 Oct 11:105513. doi: 10.1016/j.meegid.2023.105513. Online ahead of print.ABSTRACTIn cystic fibrosis (CF), Pseudomonas aeruginosa (Pa) is a major pathogen that can persistently colonize patients. Genetic studies showed a high diversity of Pa, the success of widespread or 'international' clones and described epidemic clones in CF and Epidemic High-Risk (ERH) clones. Here, we characterized Pa genetic diversity over time after first colonization in CF patients, with the aim of accurately describing the dynamics of colonization in a context of scarce longitudinal studies. Results represent the first genot...
Source: Infection, Genetics and Evolution - October 13, 2023 Category: Genetics & Stem Cells Authors: Chlo é Dupont Fabien Aujoulat Massilia Benaoudia Estelle Jumas-Bilak Rapha ël Chiron H élène Marchandin Source Type: research
Molecular epidemiology and recombination of enterovirus D68 in China
In this study, it was found that the dominant amino acid composition of the BC-loop and DE-loop continued to change with the epidemic of the virus; the amino acid composition also differed in different regions of the same genotypes. The ongoing genomic and molecular epidemiology of EV-D68 remains important for predicting emergence of new viruses and preventing major outbreaks of respiratory diseases.PMID:37827347 | DOI:10.1016/j.meegid.2023.105512 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 12, 2023 Category: Genetics & Stem Cells Authors: Yingying Shi Yongjuan Liu Yanli Wu Song Hu Binlian Sun Source Type: research
Molecular epidemiology and recombination of enterovirus D68 in China
In this study, it was found that the dominant amino acid composition of the BC-loop and DE-loop continued to change with the epidemic of the virus; the amino acid composition also differed in different regions of the same genotypes. The ongoing genomic and molecular epidemiology of EV-D68 remains important for predicting emergence of new viruses and preventing major outbreaks of respiratory diseases.PMID:37827347 | DOI:10.1016/j.meegid.2023.105512 (Source: Infection, Genetics and Evolution)
Source: Infection, Genetics and Evolution - October 12, 2023 Category: Genetics & Stem Cells Authors: Yingying Shi Yongjuan Liu Yanli Wu Song Hu Binlian Sun Source Type: research
Characterization of the bacterial microbiota of cattle ticks in northeastern Thailand through 16S rRNA amplicon sequencing
This study characterized the microbiota of the ticks infesting beef cattle in Thailand. Two species of ticks; Rhipicephalus microplus (n = 15) and Haemaphysalis bispinosa (n = 5), were collected in seven provinces in northeastern Thailand. Microbial community profile of ticks was examined based on sequences of the V3-V4 region of 16S rRNA gene. Proteobacteria (Pseudomonadota) was the most abundant phylum, followed by Firmicutes (Bacillota), and Actinobacteriota. Coxiella-like endosymbiont was the most abundant bacterial taxon overall (49% of sequence reads), followed by Anaplasma (8.5%), Corynebacterium (5.5%), Ehrlichia (...
Source: Infection, Genetics and Evolution - October 11, 2023 Category: Genetics & Stem Cells Authors: Tongjit Thanchomnang Rutchanee Rodpai Kanchana Thinnabut Patcharaporn Boonroumkaew Lakkhana Sadaow Ubon Tangkawanit Oranuch Sanpool Penchom Janwan Pewpan M Intapan Wanchai Maleewong Source Type: research
Characterization of the bacterial microbiota of cattle ticks in northeastern Thailand through 16S rRNA amplicon sequencing
This study characterized the microbiota of the ticks infesting beef cattle in Thailand. Two species of ticks; Rhipicephalus microplus (n = 15) and Haemaphysalis bispinosa (n = 5), were collected in seven provinces in northeastern Thailand. Microbial community profile of ticks was examined based on sequences of the V3-V4 region of 16S rRNA gene. Proteobacteria (Pseudomonadota) was the most abundant phylum, followed by Firmicutes (Bacillota), and Actinobacteriota. Coxiella-like endosymbiont was the most abundant bacterial taxon overall (49% of sequence reads), followed by Anaplasma (8.5%), Corynebacterium (5.5%), Ehrlichia (...
Source: Infection, Genetics and Evolution - October 11, 2023 Category: Genetics & Stem Cells Authors: Tongjit Thanchomnang Rutchanee Rodpai Kanchana Thinnabut Patcharaporn Boonroumkaew Lakkhana Sadaow Ubon Tangkawanit Oranuch Sanpool Penchom Janwan Pewpan M Intapan Wanchai Maleewong Source Type: research
Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 30;115:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. W...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research
Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 30;115:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. W...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research
Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 30;115:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. W...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research
Epidemiological and phylogenetic characteristics of emerging Anaplasma capra: A systematic review with modeling analysis
Infect Genet Evol. 2023 Sep 30;115:105510. doi: 10.1016/j.meegid.2023.105510. Online ahead of print.ABSTRACTAnaplasma capra, an emerging tick-borne pathogen, has caused a lot of concern since initially recognized in goats and patients in China in 2015, and has been reported in a wide range of domestic and wild animals as well as ticks worldwide, posing a threat to public health. In this systematic review, we established a comprehensive database to acquire the distribution and prevalence status of this pathogen, and collected all sequences of A. capra to summarize the details of genetic diversity by phylogenetic analysis. W...
Source: Infection, Genetics and Evolution - October 1, 2023 Category: Genetics & Stem Cells Authors: Zhe-Tao Lin Run-Ze Ye Jin-Yue Liu Xiao-Yang Wang Wen-Jie Zhu Yu-Yu Li Xiao-Ming Cui Wu-Chun Cao Source Type: research
