Correction to: Effectiveness of second-look endoscopy after gastric endoscopic submucosal dissection in patients taking antithrombotic agents: a multicenter propensity score matching analysis
(Source: Gastric Cancer)
Source: Gastric Cancer - July 30, 2022 Category: Gastroenterology Source Type: research
Heterogeneity and evolution of tumour immune microenvironment in metastatic gastroesophageal adenocarcinoma
ConclusionsOur findings revealed immune heterogeneity and co-evolution in GEA, which may inform immunotherapy decision-making. (Source: Gastric Cancer)
Source: Gastric Cancer - July 29, 2022 Category: Gastroenterology Source Type: research
The feasibility and safety of endoscopic submucosal dissection of gastric lesions larger than 5 cm
ConclusionsAbout two-thirds of curative resections were obtained with ESD for early gastric lesions larger than 5 cm, but delayed complications should be noted (Number: UMIN000047725). (Source: Gastric Cancer)
Source: Gastric Cancer - July 25, 2022 Category: Gastroenterology Source Type: research
Open versus laparoscopic gastrectomy for advanced gastric cancer: a propensity score matching analysis of survival in a western population —on behalf of the Italian Research Group for Gastric Cancer
ConclusionsLaparoscopic gastrectomy for advanced gastric cancer offers similar rates of survival when compared to open gastrectomy, with higher rates of return to intended oncologic treatment. ASA score, age-adjusted Charlson Comorbidity Index, lymph node ratio, return to intended oncologic treatment and p/ypTNM Stage, but not surgical approach, are prognostic factors for survival. (Source: Gastric Cancer)
Source: Gastric Cancer - July 21, 2022 Category: Gastroenterology Source Type: research
International Delphi consensus guidelines for follow-up after prophylactic total gastrectomy: the Life after Prophylactic Total Gastrectomy (LAP-TG) study
ConclusionWhile the evidence supporting the guidelines is limited, expert consensus provides a framework to best manage people following PTG, and could support the collection of information on the long-term effects of PTG. (Source: Gastric Cancer)
Source: Gastric Cancer - July 13, 2022 Category: Gastroenterology Source Type: research
Marked improvement of severe reflux esophagitis following proximal gastrectomy with esophagogastrostomy by the right gastroepiploic vessels-preserving antrectomy and Roux-en-Y biliary diversion
AbstractDuodenogastroesophageal reflux (DGER) following esophagectomy or gastrectomy can cause severe esophagitis, which impairs patients ’ quality of life and increases the risk of esophageal carcinogenesis. It is sometimes resistant to medical treatment, and surgical treatment is considered effective in such cases. However, an optimal operative procedure for medical treatment-resistant reflux esophagitis (RE) after proximal gastre ctomy (PG) with esophagogastrostomy (EG) has not yet been established. We performed the right gastroepiploic vessels-preserving antrectomy and Roux-en-Y biliary diversion in a 70-year-old man...
Source: Gastric Cancer - July 7, 2022 Category: Gastroenterology Source Type: research
A retrospective 5-year survival analysis of surgically resected gastric cancer cases from the Japanese Gastric Cancer Association nationwide registry (2001 –2013)
ConclusionOur detailed analysis highlights the historical changes in outcomes of surgically treated gastric malignancies in Japan, and provides robust dataset for future analysis. (Source: Gastric Cancer)
Source: Gastric Cancer - July 5, 2022 Category: Gastroenterology Source Type: research
The combination of gene hyperamplification and PD-L1 expression as a biomarker for the clinical benefit of tislelizumab in gastric/gastroesophageal junction adenocarcinoma
ConclusionsIn GEA, PD-L1 positivity, IFNγ-related gene signature and TMB-high status were positively associated with tislelizumab clinical benefit, whereas HA was associated with worse clinical outcomes. Combining PD-L1 positivity and HA − may help identify patients more likely to benefit from PD-1 blockade. (Source: Gastric Cancer)
Source: Gastric Cancer - July 2, 2022 Category: Gastroenterology Source Type: research
