Thromboembolic events in patients who received adjuvant chemotherapy for gastric cancer: a single-center retrospective study
ConclusionsTEEs occurred in fewer patients with GC who had been treated with AC than patients who had received palliative chemotherapy in previous reports. However, elderly GC patients who are undergoing AC require more careful surveillance for possible TEEs, considering relatively higher incidence of them. (Source: Gastric Cancer)
Source: Gastric Cancer - August 30, 2023 Category: Gastroenterology Source Type: research

Multicenter phase II study of capecitabine plus oxaliplatin in older patients with advanced gastric cancer: the Tokyo Cooperative Oncology Group (TCOG) GI-1601 study
ConclusionsThese findings demonstrate CapeOX's efficacy and safety in older AGC patients. (Source: Gastric Cancer)
Source: Gastric Cancer - August 23, 2023 Category: Gastroenterology Source Type: research

Prognostic value of post-operative serum procalcitonin in gastric adenocarcinoma patients undergoing radical gastrectomy: propensity score matching analysis of extended cohort from a prospective bi-center study
ConclusionsPCT concentration  ≥ 0.39 ng/mL at POD 5 was a reliable predictor for poorer prognosis in GA patients undergoing radical gastrectomy. (Source: Gastric Cancer)
Source: Gastric Cancer - August 14, 2023 Category: Gastroenterology Source Type: research

PPAR δ dysregulation of CCL20/CCR6 axis promotes gastric adenocarcinoma carcinogenesis by remodeling gastric tumor microenvironment
ConclusionsPPAR δ dysregulation of Ccl20/Ccr6 axis promotes GAC carcinogenesis by remodeling gastric tumor microenvironment. CCL20 might be a potential biomarker for the early detection and progression of GAC. (Source: Gastric Cancer)
Source: Gastric Cancer - August 12, 2023 Category: Gastroenterology Source Type: research

Numerous lesions of gastric adenocarcinoma of fundic-gland and fundic gland-mucosa type in a patient
AbstractA man in his 60  s underwent upper gastrointestinal endoscopy at our hospital, which revealed a 30-mm elevated lesion in the upper stomach (main lesion). There were several discolored, flat mucosal lesions and slightly elevated, reddish, subepithelial mass-like lesions (multiple secondary lesions) in the gastric f ornix and body. Histopathological examination of several biopsied secondary lesions revealed gastric adenocarcinoma of fundic-gland type (GA-FG) or gastric adenocarcinoma of fundic gland-mucosa type (GA-FGM). The main lesion was suspected to be GA-FGM on magnifying endoscopy with narrow-band imaging . It...
Source: Gastric Cancer - August 11, 2023 Category: Gastroenterology Source Type: research

Addition of docetaxel to S-1 results in significantly superior 5-year survival outcomes in Stage III gastric cancer: a final report of the JACCRO GC-07 study
ConclusionThe survival benefit of postoperative chemotherapy with S-1 and docetaxel in terms of 5-year overall survival rate was confirmed for patients with pathologically Stage III gastric cancer, although late recurrences were not prevented. (Source: Gastric Cancer)
Source: Gastric Cancer - August 7, 2023 Category: Gastroenterology Source Type: research

Collagen-related gene expression level predicts the prognosis and immune therapy response
ConclusionCS was verified as an independent prognostic factor and potentially reflected the therapeutic effect of immunotherapy. The CS could provide a new way to evaluate the clinical prognosis and response information helping develop the collagen-targeted treatment. (Source: Gastric Cancer)
Source: Gastric Cancer - August 6, 2023 Category: Gastroenterology Source Type: research

Endoscopic differential diagnosis between foveolar-type gastric adenoma and gastric hyperplastic polyps in Helicobacter pylori-na ïve patients
ConclusionsComposite diagnostic index contributes to the reproducible, accurate, preoperative differential diagnosis of FGA and HpN-GHP. (Source: Gastric Cancer)
Source: Gastric Cancer - August 6, 2023 Category: Gastroenterology Source Type: research

Collagen-related gene expression level predicts the prognosis and immune therapy response
ConclusionCS was verified as an independent prognostic factor and potentially reflected the therapeutic effect of immunotherapy. The CS could provide a new way to evaluate the clinical prognosis and response information helping develop the collagen-targeted treatment. (Source: Gastric Cancer)
Source: Gastric Cancer - August 6, 2023 Category: Gastroenterology Source Type: research

Endoscopic differential diagnosis between foveolar-type gastric adenoma and gastric hyperplastic polyps in Helicobacter pylori-na ïve patients
ConclusionsComposite diagnostic index contributes to the reproducible, accurate, preoperative differential diagnosis of FGA and HpN-GHP. (Source: Gastric Cancer)
Source: Gastric Cancer - August 6, 2023 Category: Gastroenterology Source Type: research