Examination of basic motor skills in children and adolescents
Conclusion: According to the study results, age is an essential factor for balance skills. As the age increased, the overall scores of the KTK increased. It was determined that girls’ KTK backward balancing scores were higher than boys. According to BMI results, the balance performances of obese children were found to be lower than the other groups. This difference can be explained by the negative effect of obesity in this age group. According to these results, it may be recommended to observe and improve the balance performances of obese children. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 28, 2024 Category: Physiology Source Type: research
Editorial: Training and performance in canoe slalom
(Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 27, 2024 Category: Physiology Source Type: research
Passive heating-induced changes in muscle contractile function are not further augmented by prolonged exposure in young males experiencing moderate thermal stress
Conclusion: PH induces changes in muscle contractile function which are not augmented by prolonged exposure when thermal stress is moderate. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 27, 2024 Category: Physiology Source Type: research
Editorial: The physiological effects of vibration therapy in health and disease
(Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 27, 2024 Category: Physiology Source Type: research
Microglial reactivity in brainstem chemosensory nuclei in response to hypercapnia
Microglia, the resident immune cells of the CNS, surveil, detect, and respond to various extracellular signals. Depending on the nature of these signals, an integrative microglial response can be triggered, resulting in a phenotypic transformation. Here, we evaluate whether hypercapnia modifies microglia phenotype in brainstem respiratory-related nuclei. Adult C57BL/6 inbred mice were exposed to 10% CO2 enriched air (hypercapnia), or pure air (control), for 10 or 30 min and immediately processed for immunohistochemistry to detect the ubiquitous microglia marker, ionized calcium binding adaptor molecule 1 (Iba1). Hypercapn...
Source: Frontiers in Physiology - February 27, 2024 Category: Physiology Source Type: research
Photoplethysmogram beat detection using Symmetric Projection Attractor Reconstruction
We present a novel method which uses the Symmetric Projection Attractor Reconstruction (SPAR) method to generate an attractor in a two dimensional phase space from the PPG signal. We can then define a line through the origin of this phase space to be a Poincaré section, as is commonly used in dynamical systems. Beats are detected when the attractor trajectory crosses the Poincaré section. By considering baseline drift, we define an optimal Poincaré section to use. The performance of this method was assessed using the WESAD dataset, achieving median F1 scores of 74.3% in the Baseline phase, 63.0% during Stress, 93.6% dur...
Source: Frontiers in Physiology - February 26, 2024 Category: Physiology Source Type: research
Effects of accumulated exercise on the stiffness and hemodynamics of the common carotid artery
Conclusion: There is no significant difference in the acute effects of continuous exercise and accumulated exercise on the arterial stiffness and diameter of the carotid artery. Compared with continuous exercise, accumulated exercise with an increased number of bouts is more effective in increasing cerebral blood supply and blood pressure regulation, and its oscillatory shear index recovers faster. However, the improvement of blood flow resistance in continuous exercise was better than that in accumulated exercise. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 26, 2024 Category: Physiology Source Type: research
The interactions between ineffective erythropoiesis and ferroptosis in β-thalassemia
In Guangxi, Hainan, and Fujian Province in southern China, β-thalassemia is a frequent monogenic hereditary disorder that is primarily defined by hemolytic anemia brought on by inefficient erythropoiesis. It has been found that ineffective erythropoiesis in β-thalassemia is closely associated with a high accumulation of Reactive oxygen species, a product of oxidative stress, in erythroid cells. During recent years, ferroptosis is an iron-dependent lipid peroxidation that involves abnormalities in lipid and iron metabolism as well as reactive oxygen species homeostasis. It is a recently identified kind of programmed cell ...
Source: Frontiers in Physiology - February 26, 2024 Category: Physiology Source Type: research
In silico models of the macromolecular NaV1.5-KIR2.1 complex
In this study, we present in silico 3D models of NaV1.5-KIR2.1, generated by rigid-body protein-protein docking programs and deep learning-based AlphaFold-Multimer software. Modeling revealed that the two channels could physically interact with each other along the entire transmembrane region. Structural mapping of disease-associated mutations revealed a hotspot at this interface with several trafficking-deficient variants in close proximity. Thus, examining the role of disease-causing variants is important not only in isolated channels but also in the context of macromolecular complexes. These findings may contribute to a...
Source: Frontiers in Physiology - February 26, 2024 Category: Physiology Source Type: research
Swimming behavior indicates stress and adaptations to exercise
Discussion: These results suggest that swimming behavior during training indicates individualized adaptations to long-term exercise, and highlight a biological significance of swimming behavior monitoring in animal studies. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 26, 2024 Category: Physiology Source Type: research
Editorial: Male fertility: lessons learnt from the SARS-CoV-2 pandemic
(Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 26, 2024 Category: Physiology Source Type: research
Editorial: Pathophysiology of bone and mineral metabolism
(Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 23, 2024 Category: Physiology Source Type: research
Serum cytokine profile of neonatal broiler chickens infected with Salmonella Typhimurium
The objective of this experiment was to evaluate 12 cytokines. Day of hatch male chicks were randomly allocated into a control or ST challenged group. At day three of age, sterile diluent or 5.0 × 108 CFU of ST was given orally to each chick. Blood was obtained 24 h post challenge and serum separated for later analysis (n = 30 chicks/treatment). Significant (p ≤ 0.05) increases in pro-inflammatory cytokines-interleukin-6 (IL-6), IL-16, and IL-21; anti-inflammatory cytokines- IL-10; chemokines-regulated on activation, normal T cell expressed and secreted (RANTES), macrophage inflammatory protein-1β (MIP-1β), and MIP-...
Source: Frontiers in Physiology - February 23, 2024 Category: Physiology Source Type: research
Myofibroblasts impair myocardial impulse propagation by heterocellular connexin43 gap-junctional coupling through micropores
Conclusion: Heterocellular Cx43 gap junction coupling of CMs with MFs alters the spatiotemporal patterns of myocardial impulse propagation, even in the absence of spatially interjacent and mechanosensitive modulations by MFs. Moreover, MFs can promote pro-arrhythmogenic impulse propagation when in face-to-face contact with the myocardium that arises in the healing infarct border zone. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 23, 2024 Category: Physiology Source Type: research
Insights into the unique roles of dermal white adipose tissue (dWAT) in wound healing
Dermal white adipose tissue (dWAT) is a newly recognized layer of adipocytes within the reticular dermis of the skin. In many mammals, this layer is clearly separated by panniculus carnosus from subcutaneous adipose tissue (sWAT). While, they concentrated around the hair shaft and follicle, sebaceous gland, and arrector pili muscle, and forms a very specific cone geometry in human. Both the anatomy and the histology indicate that dWAT has distinct development and functions. Different from sWAT, the developmental origin of dWAT shares a common precursor with dermal fibroblasts during embryogenesis. Therefore, when skin inju...
Source: Frontiers in Physiology - February 23, 2024 Category: Physiology Source Type: research
