Effects of unilateral, bilateral, and combined unilateral+bilateral complex resistance training on bench press and squat strength in adolescent boxers
Discussion: UNI and UNI + BI training led to significantly higher output power values in bench press and squat exercises at 30% 1RM compared to the BI training group. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 4, 2024 Category: Physiology Source Type: research
Functionality, muscular strength and cardiorespiratory capacity in the elderly: relationships between functional and physical tests according to sex and age
Discussion: There were sex and age differences in functional, strength, and cardiorespiratory tests. The execution of quick and low-cost tests such as the CMJ and TUG could provide information on overall physical fitness in older adults. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 1, 2024 Category: Physiology Source Type: research
Quadriceps muscle atrophy after non-invasive anterior cruciate ligament injury: evidence linking to autophagy and mitophagy
Conclusion: These data highlight the complexity of muscle recovery after ACL injury and underscore the overlooked but crucial role of autophagy and mitophagy in promoting the recovery process. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 1, 2024 Category: Physiology Source Type: research
Biocontrol efficacy of cajeput oil against Anopheles stephensi L. mosquito and its effect on non-target species
In this study, we assessed the phytochemical, biochemical, and insecticidal properties of the chemical constituents of cajeput oil. Results show that Melaleuca cajuputi essential oil may exhibit mosquito larvicidal properties against Anopheles stephensi larvae (second-fourth instar) at 24 h post-treatment. At 24 h post-exposure, the essential oil resulted in a significant decrease in detoxifying enzymes. All of these findings indicate that cajeput oil infects An. stephensi larvae directly affect the immune system, leading to decreased immune function. Cajeput oil significantly affects the second, third, and fourth instar...
Source: Frontiers in Physiology - March 1, 2024 Category: Physiology Source Type: research
Deficits in proprioception and strength may contribute to the impaired postural stability among individuals with functional ankle instability
Conclusion: Individuals with FAI have worse postural stability and proprioception and less strength. Their proprioception and strength decreased to a point where they could not provide sufficient functional assistance to the ML postural stability. Improvements in proprioception and strength may be keys to prevent recurrent ankle sprains among individuals with FAI. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - March 1, 2024 Category: Physiology Source Type: research
Bone and bone derived factors in kidney disease
Purpose of review: Mineral and bone disorder (MBD) is a prevalent complication in chronic kidney disease (CKD), significantly impacting overall health with multifaceted implications including fractures, cardiovascular events, and mortality. Despite its pervasive nature, effective treatments for CKD-MBD are lacking, emphasizing the urgency to advance understanding and therapeutic interventions. Bone metabolism intricacies, influenced by factors like 1,25 dihydroxy vitamin D, parathyroid hormone (PTH), and fibroblast growth factor 23 (FGF23), along with intrinsic osseous mechanisms, play pivotal roles in CKD. Skeletal abnorm...
Source: Frontiers in Physiology - March 1, 2024 Category: Physiology Source Type: research
Bringing into focus the central domains C3-C6 of myosin binding protein C
Myosin binding protein C (MyBPC) is a multi-domain protein with each region having a distinct functional role in muscle contraction. The central domains of MyBPC have often been overlooked due to their unclear roles. However, recent research shows promise in understanding their potential structural and regulatory functions. Understanding the central region of MyBPC is important because it may have specialized function that can be used as drug targets or for disease-specific therapies. In this review, we provide a brief overview of the evolution of our understanding of the central domains of MyBPC in regard to its domain st...
Source: Frontiers in Physiology - February 29, 2024 Category: Physiology Source Type: research
Uridine and its role in metabolic diseases, tumors, and neurodegenerative diseases
This article summarizes the latest findings about the metabolic effects of uridine and the potential of uridine metabolism as therapeutic target in treatment of metabolic disorders. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 29, 2024 Category: Physiology Source Type: research
The prognostic value of preoperative D-dimer to albumin ratio for overall survival and progression-free survival in colorectal cancer
Conclusion: Preoperative DAR is a promising biomarker for predicting PFS and OS among patients with CRC. The DAR-based prognostic prediction nomogram may serve as an effective tool for the comprehensive assessment of prognosis in patients with CRC. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 29, 2024 Category: Physiology Source Type: research
Evaluation of the photoprotective and antioxidant potential of an avobenzone derivative
This study demonstrated that structural modifications of avobenzone can lead to the development of a broad spectrum (absorbing UVB and UVA II radiation, as well as a portion of the UVA I radiation), non-phototoxic, non-photoreactive and photostable derivative for sunscreen and anti-aging formulations. This derivative enhances protection against oxidative stress induced by UV radiation and improves the effectiveness of sun protection. In addition to the monolayer model, the use of a standardized in-house RHS model was highly relevant for evaluating the effects of UV radiation and skin aging. This model closely mimics human ...
Source: Frontiers in Physiology - February 29, 2024 Category: Physiology Source Type: research
Translational frontiers: insight from lymphatics in skin regeneration
The remarkable regenerative ability of the skin, governed by complex molecular mechanisms, offers profound insights into the skin repair processes and the pathogenesis of various dermatological conditions. This understanding, derived from studies in human skin and various model systems, has not only deepened our knowledge of skin regeneration but also facilitated the development of skin substitutes in clinical practice. Recent research highlights the crucial role of lymphatic vessels in skin regeneration. Traditionally associated with fluid dynamics and immune modulation, these vessels are now recognized for interacting wi...
Source: Frontiers in Physiology - February 29, 2024 Category: Physiology Source Type: research
miR-146a is a critical target associated with multiple biological pathways of skin aging
Conclusion: miR-146a interacts with multiple biological pathways related to skin aging, including circadian rhythm machinery, cell-to-cell communication, cell damage repair, cell proliferation, and collagen production and represents a promising target to fight skin aging. Adansonia digitata extract can promote miR-146a expression and therefore support skin cells’ health. (Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 29, 2024 Category: Physiology Source Type: research
TRP channels: a provocative rationalization for local Ca2+ control in arterial tone development
Arterial networks are controlled by the consolidated output of stimuli that set “how much” (magnitude) and “where” (distribution) blood flow is delivered. While notable changes in magnitude are tied to network wide responses, altered distribution often arises from focal changes in tone, whose mechanistic foundation remains unclear. We propose herein a framework of focal vasomotor contractility being controlled by pharmacomechanical coupling and the generation of Ca2+ waves via the sarcoplasmic reticulum. We argue the latter is sustained by receptor operated, transient receptor potential (TRP) channels through direc...
Source: Frontiers in Physiology - February 28, 2024 Category: Physiology Source Type: research
Mechanisms of endometrial aging: lessons from natural conceptions and assisted reproductive technology cycles
Until recently, the study of age-related decline in fertility has focused primarily on the ovary; depletion of the finite pool of oocytes and increases in meiotic errors leading to oocyte aneuploidy are well-established mechanisms by which fertility declines with advancing age. Comparatively little is known about the impact of age on endometrial function. The endometrium is a complex tissue comprised of many cell types, including epithelial, stromal, vascular, immune and stem cells. The capacity of this tissue for rapid, cyclic regeneration is unique to this tissue, undergoing repeated cycles of growth and shedding (in the...
Source: Frontiers in Physiology - February 28, 2024 Category: Physiology Source Type: research
Editorial: Calcium regulation and Mechano-transduction in vascular diseases: obligatory role of transient receptor potential and Piezo channels
(Source: Frontiers in Physiology)
Source: Frontiers in Physiology - February 28, 2024 Category: Physiology Source Type: research
