Assessment of pheniramine in alternative biological matrices by liquid chromatography tandem mass spectrometry
In this study, pheniramine was quantified in both conventional and alternative specimens of twenty chronic drug abusers, aged 16 –50 years, who were positive for pheniramine in comprehensive toxicological screening for drugs by gas chromatography with mass spectral detection in positive electron impact mode. Pheniramine was extracted from biological specimens using solid phase extraction and liquid chromatography tandem ma ss spectrometry was employed for quantification. Chromatographic separation was carried out on a Poroshell120EC-18 (2.1 mm × 50 mm × 2.7 µm) column using water-acetonitrile in formic acid (0...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research

Effects of antibiotics ceftriaxone and levofloxacin on the growth of Protophormia terraenovae (Diptera: Calliphoridae)
In this study the effects of different concentrations of antibiotics levofloxacin and ceftriaxone on maggot development, weight, length, and mortality were examined. The maggot length and weight were significantly increased by therapeutical doses of levofloxacin and ceftriaxone. The maggot development time was significantly decreased in every levofloxacin treatment compared to the control. The time to start pupation was significantly increased in the control compared to the antibiotic treatments. Levofloxacin significantly increased the survivability of the maggots. Every levofloxacin treatment significantly improved the r...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research

Commentary on: Management of unidentified and unclaimed bodies: a comparison of model from four countries in the Asia Pacific Region
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research

Assessment of pheniramine in alternative biological matrices by liquid chromatography tandem mass spectrometry
In this study, pheniramine was quantified in both conventional and alternative specimens of twenty chronic drug abusers, aged 16 –50 years, who were positive for pheniramine in comprehensive toxicological screening for drugs by gas chromatography with mass spectral detection in positive electron impact mode. Pheniramine was extracted from biological specimens using solid phase extraction and liquid chromatography tandem ma ss spectrometry was employed for quantification. Chromatographic separation was carried out on a Poroshell120EC-18 (2.1 mm × 50 mm × 2.7 µm) column using water-acetonitrile in formic acid (0...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research

Effects of antibiotics ceftriaxone and levofloxacin on the growth of Protophormia terraenovae (Diptera: Calliphoridae)
In this study the effects of different concentrations of antibiotics levofloxacin and ceftriaxone on maggot development, weight, length, and mortality were examined. The maggot length and weight were significantly increased by therapeutical doses of levofloxacin and ceftriaxone. The maggot development time was significantly decreased in every levofloxacin treatment compared to the control. The time to start pupation was significantly increased in the control compared to the antibiotic treatments. Levofloxacin significantly increased the survivability of the maggots. Every levofloxacin treatment significantly improved the r...
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research

Commentary on: Management of unidentified and unclaimed bodies: a comparison of model from four countries in the Asia Pacific Region
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - March 26, 2024 Category: Forensic Medicine Source Type: research

The micro CT evaluation of crown and root pulp volume versus dentin thickness in teeth in postmortem interval (PMI)
AbstractDetermining the postmortem interval (PMI) is one of the main study subjects of forensic sciences. The main purpose of this prospective in vitro study that was the Micro-CT evaluation of teeth crown and root pulp volume versus dentin thickness in terms of PMI determination. The study involved 60 female Wistar rats, with weights ranging from 270 to 320  g. These rats were grouped into six different post-mortem period categories. Following the animals’ sacrifice, they were subjected to a natural putrefaction period, with a control group, in the grounds of a sheltered garden. Hemi-mandible samples were then extracte...
Source: Forensic Science, Medicine, and Pathology - March 21, 2024 Category: Forensic Medicine Source Type: research

Corpse or not? Two peculiar cases of misidentification
SummaryIrrespective of whether they are intended for collectors or for the fetish market, dolls are being produced to look more and more realistic with such a degree of life-like detail that they can be mistaken for a real person. This paper reports two cases of misidentification due to this increasing similarity: In the first case, a sex doll was mistaken for a corpse; in the second case, a corpse was mistaken for a doll. While in the latter case, only medical laypersons were at the discovery site, in the first case, an emergency doctor had issued a medical certificate of death for the purported corpse. The medicolegal ex...
Source: Forensic Science, Medicine, and Pathology - March 15, 2024 Category: Forensic Medicine Source Type: research

Sustainable and economical alternatives to fragment capture materials in explosive and ballistic trials
AbstractStrawboard has been utilised as a fragmentation capture material since the 1960s, mainly employed to capture fragments from explosives and explosive devices from arena trials of munitions. As this material has historically been calibrated to a known standard, it has a proven record of allowing research establishments to ascertain the velocity of a fragment based on the depth of penetration of the strawboard. During the time of calibration, strawboard was used as a common building material which was both widely available and relatively affordable; however, due to the recent economic crisis and geopolitical supply is...
Source: Forensic Science, Medicine, and Pathology - March 12, 2024 Category: Forensic Medicine Source Type: research

Comparative analysis of post-mortem drug concentrations in cerebrospinal fluid and blood
This study aimed to compare the concentration of various xenobiotics in both cerebrospinal fluid (CSF) and blood. We examined 175 autopsy cases covering a wide range of ages, causes of death, and drug ingestion histories, with cerebrospinal fluid and blood samples available for toxicological testing. Analytes studied included opioids, benzodiazepines, antidepressants, antipsychotics, and illicit substances such as cannabinoids, stimulants and new psychoactive substances, including synthetic cathinones and synthetic cannabinoids. We found that concentrations in CSF were generally lower than in blood. A significant correlati...
Source: Forensic Science, Medicine, and Pathology - March 12, 2024 Category: Forensic Medicine Source Type: research

Sustainable and economical alternatives to fragment capture materials in explosive and ballistic trials
AbstractStrawboard has been utilised as a fragmentation capture material since the 1960s, mainly employed to capture fragments from explosives and explosive devices from arena trials of munitions. As this material has historically been calibrated to a known standard, it has a proven record of allowing research establishments to ascertain the velocity of a fragment based on the depth of penetration of the strawboard. During the time of calibration, strawboard was used as a common building material which was both widely available and relatively affordable; however, due to the recent economic crisis and geopolitical supply is...
Source: Forensic Science, Medicine, and Pathology - March 12, 2024 Category: Forensic Medicine Source Type: research

Comparative analysis of post-mortem drug concentrations in cerebrospinal fluid and blood
This study aimed to compare the concentration of various xenobiotics in both cerebrospinal fluid (CSF) and blood. We examined 175 autopsy cases covering a wide range of ages, causes of death, and drug ingestion histories, with cerebrospinal fluid and blood samples available for toxicological testing. Analytes studied included opioids, benzodiazepines, antidepressants, antipsychotics, and illicit substances such as cannabinoids, stimulants and new psychoactive substances, including synthetic cathinones and synthetic cannabinoids. We found that concentrations in CSF were generally lower than in blood. A significant correlati...
Source: Forensic Science, Medicine, and Pathology - March 12, 2024 Category: Forensic Medicine Source Type: research