Forensic Science, Medicine, and Pathology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Under-reporting of forensic findings: craniocervical emergency imaging in cases of survived hanging
Abstract To determine the diagnostic bias between clinical and forensic radiology in cases of nonfatal hanging and determine and describe typical underreported imaging findings. In a retrospective, single-center study, all patients admitted for attempted suicide with near-hanging or fatal hanging between January 2008 and December 2020 who received CT or MRI of head and neck were reviewed and missed findings in the original report were documented. A binary regression with disagreement as dependent variable was fitted for the imaging modality, fatality, age, and sex. A total of 123 hanging incidents were retrospectively a...
Source: Forensic Science, Medicine, and Pathology - June 20, 2023 Category: Forensic Medicine Source Type: research

Diagnostic challenges and forensic implications in a case of infantile fatal myocarditis
We present the case of a 23-month-old child who died less than 24  h after the onset of cardiac symptoms, despite being admitted to the hospital 72 h earlier. Autopsy revealed no significant macroscopic changes, and histologic examination revealed focal lymphocytic myocarditis with myocyte disruption, diffuse alveolar damage in the exudative phase, and generaliz ed lymphocytic immune activation in other organs. Ante-mortem and post-mortem microbiological exams did not clearly prove a causative role of infectious agents. The peculiarity of this case was characterized by the contrast between the severe clinical features a...
Source: Forensic Science, Medicine, and Pathology - June 19, 2023 Category: Forensic Medicine Source Type: research

Sphenoid sinuses ’ volume and area analysis of Brazilian individuals’ CBCTs, related to sex, age, skin color, and nutritional status using DDS-Pro™ software
AbstractThe purpose of this study was to analyze the volume and area of sphenoid sinuses of Brazilian individuals ’ cone-beam computed tomography (CBCT) images using the beta version of the DDS-Pro™ 2.14.2_2022 software (DPP Systems, Czestochowa, Poland), to assess a potential correlation to sex, age, skin color, and nutritional status, and to evaluate differences between the right and left sides. Three-dim ensional volume and area measurements were made with the software using CBCT images of 113 living Brazilian individuals of both sexes (67 females and 46 males). TEM, rTEM, andR were used to assess the reproducibilit...
Source: Forensic Science, Medicine, and Pathology - June 17, 2023 Category: Forensic Medicine Source Type: research

A harmful MYH11 variant detected in a family with thoracic aortic dissection and patent ductus arteriosus
We present this familial case to stress the necessity of postmortem genetic testing in such cases among forensic practices. Identifying those culprit gene variants can direct effective genetic counseling and personalized health management in family members (especially first-degree relatives) with high-risk genotypes. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - June 12, 2023 Category: Forensic Medicine Source Type: research

Acknowledgements
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - June 9, 2023 Category: Forensic Medicine Source Type: research

Multiorgan immunohistochemical endothelial expression of E-selectin in a forensic case of sepsis
This report describes the gross pathological findings obtained from the autopsy of a 48-year-old woman with Crohn ’s disease after surgical intervention. Macroscopically, we found intestinal perforation and signs of peritonitis. Histologically, the pulmonary/bronchial arteries were lined with E-selectin (CD 62E)-positive endothelial cells, which are an established postmortem histological marker of sepsis. We extended our investigations to the cerebral cortex and subcortical medullary layer. The endothelium of the cortical vessels and those in the cerebral medullary layer were likewise immunopositive for E-selectin. Furth...
Source: Forensic Science, Medicine, and Pathology - June 8, 2023 Category: Forensic Medicine Source Type: research

Prediction of exophthalmos by body mass index for craniofacial reconstruction: consequences for cold cases
The objective of this study was to evaluate a non-population-dependent method of determining exophthalmos. The protrusion of the eyeball is known to vary with the contents of the orbital cavity based on bony orbital resorption or increased or decreased fat contents, as well as according to relative eyeball size. Of use are available statistics on body mass index, and this is discussed within the context of eyeball protrusion. A weak positive correlation (0.3263) between the body mass index of the country where the study originated, and the degree of exophthalmos was found. The results suggest that eyeball protrusion rates ...
Source: Forensic Science, Medicine, and Pathology - June 7, 2023 Category: Forensic Medicine Source Type: research

Age estimation from iliac auricular surface using Bayesian inference and principal component analysis: a CT-based study in an Indian population
AbstractAge estimation constitutes one of the pillars of human identification. The auricular surface of the ilium presents as a durable and robust structure within the human skeletal framework, capable of enabling accurate age estimation in older adults. Amongst different documented auricular age estimation methods, the Buckberry-Chamberlain method offers greater objectivity through its component-based approach. The present study aimed to test the applicability of the Buckberry-Chamberlain method in an Indian population through a CT-based examination of the auricular surface. CT scans of 435 participants undergoing CT exam...
Source: Forensic Science, Medicine, and Pathology - June 6, 2023 Category: Forensic Medicine Source Type: research

A pilot study investigating early postmortem interval of rats based on ambient temperature and postmortem interval-related metabolites in blood
In this study, gas chromatography –mass spectrometry (GC‒MS)‒based metabolomics was adopted to explore the changes in metabolites in the cardiac blood of suffocated rats at various ambient temperatures (5 °C, 15 °C, 25 °C, and 35 °C) from 0 to 24 h after death. Isoleucine, alanine, proline, valine, glycerol, glycerol phosphate, xanthine, and hypoxanthine were found to contribute to PMI in all temperature groups. Hypoxanthine and isoleucine were chosen to establish estimation models (equations) with an interpolation function using PMI as the dependent variable (f(x, y)), relative intensity as the independent ...
Source: Forensic Science, Medicine, and Pathology - June 2, 2023 Category: Forensic Medicine Source Type: research