Suicide by vaping the synthetic cannabinoid 4F-MDMB-BINACA: cannabinoid receptors and fluoride at the crossroads of toxicity?
AbstractA 22-year-old man was hospitalized after stating he would ‘commit suicide in a non-detectable way’. He was admitted with a severe necrotizing pancreatitis and acute kidney injury, evolving to multiple organ failure. His condition rapidly deteriorated, and he died 11 days after hospital admission. Postmortem histopathology confirmed fulminant necrotizi ng pancreatitis, acute tubular necrosis, cerebral edema, pericentral/midzonal hepatocellular necrosis and acute respiratory distress syndrome. Metabolites of 4F-MDMB-BINACA, a synthetic cannabinoid, were detected in urine and serum collected at hospit...
Source: Forensic Science, Medicine, and Pathology - September 20, 2021 Category: Forensic Medicine Source Type: research

Beyond the visible spectrum – applying 3D multispectral full-body imaging to the VirtoScan system
AbstractMultispectral photography offers a wide range of applications for forensic investigations. It is commonly used to detect latent evidence and to enhance the visibility of findings. Additionally, three-dimensional (3D) full-body documentation has become much easier and more affordable in recent years. However, the benefits of performing 3D imaging beyond the visible (VIS) spectrum are not well known, and the technique has not been widely used in forensic medical investigations. A multicamera setup was used to employ multispectral photogrammetry between 365 and 960  nm in postmortem investigations. The multicamer...
Source: Forensic Science, Medicine, and Pathology - September 17, 2021 Category: Forensic Medicine Source Type: research

Colorectal barotrauma following compressed air spray to the perineum
AbstractColorectal injuries caused by high-pressure air compressors are rare and reported especially among industrial workers. They may appear because of intended or accidental injury. In the present paper, we report a case of colorectal injuries due to air insufflation from a distance towards the anus with the clothes on, as a means of a practical joke. The patient presented one day after the trauma to the Emergency Department with complaints of severe abdominal pain and vomiting. On examination, he had signs of peritonitis. A computed tomography (CT) scan did not show any perforation. Emergency laparotomy was performed w...
Source: Forensic Science, Medicine, and Pathology - September 17, 2021 Category: Forensic Medicine Source Type: research

Regarding ‘traumatic herniation of intestine through ruptured skin at the ankle’
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - September 16, 2021 Category: Forensic Medicine Source Type: research

A study into the viability of Synbone ® as a proxy for Sus scrofa (domesticus) ribs for use with 7.62 × 51 mm Full Metal Jacket ammunition in ballistic testing
This study aims to determine if Synbone ® flat plates could be a viable proxy forSus scrofa (domesticus) ribs in ballistic testing with 7.62  × 51 mm Full Metal Jacket ammunition. 5 mm, 6 mm and 12 mm quartered Synbone® plates were embedded into 10% ballistic gelatin and shot using 7.62 mm ammunition. The models were then analysed to compare the Synbone® to a previousSus Scrofa (domesticus) rib study and focused on energy deposition, the number of fragments within the block, angle of deviation, onset of yaw, the temporary cavity, and the permanent wound channel. No s...
Source: Forensic Science, Medicine, and Pathology - September 8, 2021 Category: Forensic Medicine Source Type: research

Importance of dashboard camera (Dash Cam) analysis in fatal vehicle –pedestrian crash reconstruction
AbstractThe reconstruction of dynamic of traffic injuries remains a challenge in forensic pathology and is often based on circumstantial data. Dash Cams are digital video recorders which can be located inside a vehicle and continuously record the view through the windscreen, thus providing objective evidence.  Here we present the case of a traffic crash in which a pedestrian was hit by an articulated lorry. The analysis of a video recorded from a Dash Cam retrieved inside the vehicle during the death scene investigation (DSI) was crucial in the reconstruction of the manner of death. Indeed, the death, w hich was initi...
Source: Forensic Science, Medicine, and Pathology - September 1, 2021 Category: Forensic Medicine Source Type: research

Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major players IL-1 β, IL-6, IL-15 and TNF-α
This study involves the histological analysis of samples taken during autopsies in cases of COVID-19 related death to evaluate the inflammatory cytokine response and the tissue localization of the virus in various organs. In all the selected cases, SARS-CoV-2 RT-PCR on swabs collected from the upper (nasopharynx and oropharynx) and/or the lower respiratory (trachea and primary bronchi) tracts were positive. Tissue localization of SARS-CoV-2 was detected using antibodies against the nucleoprotein and the spike protein. Overall, we tested the hypothesis that the overexpression of proinflammatory cytokines plays an important ...
Source: Forensic Science, Medicine, and Pathology - August 31, 2021 Category: Forensic Medicine Source Type: research

Sudden death after being in a bounce house: a late complication of congenital diaphragmatic hernia
AbstractA 3-year-old white female with no significant past medical history was found unresponsive and apneic after several hours of vomiting. The patient had reportedly felt unwell since jumping in a bounce house at a festival earlier in the day. After one hour of attempted resuscitation by EMS and hospital staff, the patient was pronounced deceased. On autopsy there was a 3 cm opening in the left posterolateral hemidiaphragm with the spleen, the stomach, and portions of the small and large bowel displaced into the left chest cavity, resulting in compression of both lungs and the heart to the right side of the chest. The r...
Source: Forensic Science, Medicine, and Pathology - August 27, 2021 Category: Forensic Medicine Source Type: research

Recognition and confirmation of Fox sign
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - August 27, 2021 Category: Forensic Medicine Source Type: research

Mob justice fatalities in South Africa: a forensic mortuary study
The objectives were to describe the demographics of the victims of fatal mob justice, describe the trends of the number of fatalities and causes of death over time, assess hospitalization frequency , describe the nature and location of injuries sustained, and to report on ancillary investigations performed. A total of 354 cases were analyzed. All victims were Black (100%), with 99.4% of the sample group being male. The largest proportion was aged between 21–30 years (49.2%) with the majorit y having South African citizenship (68.9%). The majority of deaths were due to blunt force injuries (92.4%) with blunt forc...
Source: Forensic Science, Medicine, and Pathology - August 26, 2021 Category: Forensic Medicine Source Type: research

The potential side effects of herbal preparations in domestic animals
AbstractA recent series of deaths in previously healthy dogs in Victoria, Australia associated with the ingestion of raw meat contaminated by indospicine derived from native Australian plants of theIndigofera species draws attention to the potential that exists for herbal toxicity in domestic animals. Although the efficacy of herbal remedies generally remains unproven in domestic animals, herbal preparations are being increasingly used as supplements and treatments. Issues with incorrect ingredients, inadequate processing, faulty, incomplete or inaccurate product labelling, contamination with toxins, adulteration with unde...
Source: Forensic Science, Medicine, and Pathology - August 21, 2021 Category: Forensic Medicine Source Type: research

Sudden death due to leukostasis in a subject with undiagnosed chronic lymphocytic leukemia
We present a case of a 70-year-old man who died suddenly in the absence of symptoms. Autopsy and histology examinations revealed findings consistent with CLL and diffuse leukostasis involving the major organs ’ vessels.In the presence of gross and/or microscopic findings suggesting a potential hematologic malignancy, undiagnosed or relapsing hematologic malignancies should be considered in the differential diagnosis of sudden deaths. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - August 20, 2021 Category: Forensic Medicine Source Type: research

Organ transplantation in Arabian Gulf countries: ethical and legal practice and beyond
This article aims to cover the history of organ transpl antation, brain death diagnosis protocols, organ donation enrollment policies and conditions, as well as the issue of organ trafficking in Arabian Gulf countries. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - August 18, 2021 Category: Forensic Medicine Source Type: research

Comparison of superficial wound documentation using 2D forensic photography, 3D photogrammetry, Botscan © and VR with real-life examination
AbstractEvidence acquisition, interpretation and preservation are essential parts of forensic case work that make a standardized documentation process fundamental. The most commonly used method for the documentation and interpretation of superficial wounds is a combination of two modalities: two-dimensional (2D) photography for evidence preservation and real-life examination for wound analysis. As technologies continue to develop, 2D photography is being enhanced with three-dimensional (3D) documentation technology. In our study, we compared the real-life examination of superficial wounds using four different technical doc...
Source: Forensic Science, Medicine, and Pathology - August 18, 2021 Category: Forensic Medicine Source Type: research

Expression of Fc εRIα and tryptase in human lung tissue during drug-induced anaphylactic death
AbstractThe diagnosis of drug-induced anaphylactic death is an important component of forensic medicine. The purpose of this study was to explore the expression of Fc εRIα and tryptase in human lung tissue during drug-induced anaphylactic death and its value for forensic medicine. The expression of FcεRIα and tryptase in lung tissues of the drug-induced anaphylactic death group (n = 30) and control group (who died due to sudden cardiac death, falling from a height, or traffic accidents, n = 30) was detected by immunohistochemistry and immunofluorescence staining. The&...
Source: Forensic Science, Medicine, and Pathology - August 12, 2021 Category: Forensic Medicine Source Type: research

Medullary thyroid carcinoma with diabetic ketoacidosis: an autopsy case report and literature review
AbstractMedullary thyroid carcinoma (MTC) is a rare neuroendocrine tumor of parafollicular C cells. The majority of MTCs occur sporadically, but about 30% of the cases are associated with multiple endocrine neoplasia type 2 (MEN2) syndrome or familial MTC. Generally, MTCs have no clinical manifestation, but infrequently the patients develop symptoms of hypercortisolism by secreting adrenocorticotropic hormone (ACTH) or corticotropin-releasing hormone (CRH). Although ectopic Cushing syndrome is only found in 0.7% of MTC patients, it can lead to fatal consequences if left untreated. Over 50 cases of MTC-related Cushing syndr...
Source: Forensic Science, Medicine, and Pathology - August 12, 2021 Category: Forensic Medicine Source Type: research

Correction to: Rapid development of an iatrogenic aortic dissection following transcatheter aortic valve implantation
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - August 4, 2021 Category: Forensic Medicine Source Type: research

Cryptococcosis and unexpected death
AbstractCryptococcosis is a fungal disease caused predominantly byCryptococcus neoformans andCryptococcus gatti. It is most often found in immunocompromised individuals and has quite protean and chronic manifestations affecting all body systems. The unexpected death of a 22-year-old man with cryptococcal meningoencephalitis demonstrates, however, that it may have a fulminant course in previously well individuals. Also present at autopsy was a toruloma of the upper lobe of the right lung. Delays in clinical diagnoses, confusion with tuberculosis and precipitate clinical deterioration may mean that cases will be encountered ...
Source: Forensic Science, Medicine, and Pathology - July 29, 2021 Category: Forensic Medicine Source Type: research

Gastro-esophageal pharmacobezoar
AbstractA 35-year-old man with schizophrenia died from an overdose of propranolol (blood level  = 60 mg/L). Post mortem CT scanning showed marked distension of the esophagus by granular material with a bolus of similar material within the stomach. At autopsy 62 g of lime green pharmacobezoar was present within the esophagus with an additional 130gm mass of similar material within the st omach, both of which contained propranolol. The rest of the gastrointestinal tract was unremarkable. The mouth, pharynx, glottis, larynx, trachea and bronchi were all structurally normal with no obstructive material....
Source: Forensic Science, Medicine, and Pathology - July 29, 2021 Category: Forensic Medicine Source Type: research

The human intervertebral disc as a source of DNA for molecular identification
AbstractGenetic analyses such as STR-typing are routinely used for identification purposes in forensic casework. Although genotyping techniques only require a minimum amount of DNA to provide a genetic profile, DNA quality differs not only between but also within tissues during ongoing decomposition. Initiated by a recent case where, due to the constitution of the body, preferred tissue was not available or only resulted in a partial and not usable DNA profile, the analysis of intervertebral discs as a source of DNA was considered. As the analysis of this tissue resulted in a high quality DNA profile a further study was pe...
Source: Forensic Science, Medicine, and Pathology - July 22, 2021 Category: Forensic Medicine Source Type: research

Police reporting in cases of sexual assault – a 10-year study of reported cases, unreported cases, and cases with delayed reporting
AbstractThe aim of this study was to identify characteristics of reported, later-reported and unreported cases of sexual assault.  All cases with female complainants (> 15 years) of sexual assault, who had been examined at the Centre for Victims of Sexual Assault (CVSA) in the Region of Southern Denmark in a 10-year period, were included. Retrospective data were collected from medico-legal examination reports and police reports. Descriptive bivariate analysis and logistic analysis were performed.  Forensic pathologists examined 850 complainants of sexual assault in 2009-2018, of which 753 cases were included i...
Source: Forensic Science, Medicine, and Pathology - July 16, 2021 Category: Forensic Medicine Source Type: research

Academic Referencing – a dying art
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - July 16, 2021 Category: Forensic Medicine Source Type: research

Asphyxia caused by delayed subglottic stenosis after neck trauma
This report describes a rare condition in which slowly progressive intralaryngeal stenosis formation after external neck trauma could cause asphyxial death in a previously asymptomatic adult. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - July 14, 2021 Category: Forensic Medicine Source Type: research

Traumatic herniation of intestine through ruptured skin at the ankle
We report an interesting case of vehicular runover where the intestinal coils have come out of the body at the ankle. The authors describe the plausible mechanism and the route through which the intestine could have traversed. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - July 9, 2021 Category: Forensic Medicine Source Type: research

Factitious disorders in Germany –a detailed insight
AbstractFactitious disorders (FDs) are well known to a majority of physicians; however, the corresponding ICD-10 diagnosis F68.1 remains severely under assigned and often misdiagnosed. Based on a previously conducted nationwide survey in Germany, we extended the analyzed variables to further understand FD characteristics.The assignments regarding the following variables in the German diagnosis-related group statistics were analyzed: residence of the patient and location of the diagnosing institution, primary referral to the diagnosing institution, reason for admission and discharge, specialty department, total length of st...
Source: Forensic Science, Medicine, and Pathology - July 2, 2021 Category: Forensic Medicine Source Type: research

Explosion-related deaths: An overview on forensic evaluation and implications
ConclusionThe scenarios presented offer a useful instrument to avoid misinterpretations and evaluation errors. Procedural notes and technical aspects are provided to the readers, with an insight on collaboration with other forensic experts. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - July 1, 2021 Category: Forensic Medicine Source Type: research

Fox sign in a case of terminal stage pancreatic cancer and suggestions for diagnosis
AbstractSkin signs in acute pancreatitis are well-known and frequently discussed manifestations accompanied by unfavorable prognoses although they may rarely appear in clinical and forensic medicine. In 2018, the district attorney ’s office ordered a forensic autopsy for a 74-year-old man with terminal stage pancreatic cancer. The autopsy was ordered based on accusations of the deceased’s widow regarding alleged medical malpractice and poor hospital care. The widow filed a grievance about multiple unsuccessful attempts to draw blood from her husband in addition to a diaper dermatitis at the right groin. An auto...
Source: Forensic Science, Medicine, and Pathology - June 30, 2021 Category: Forensic Medicine Source Type: research

Post-mortem CT lung findings at a medicolegal institute in SARS-CoV-2 RT-PCR positive cases with autopsy correlation
AbstractCoVID-19 is a novel viral infection with now well-established clinical radiological findings. There is limited data on post-mortem imaging. We explore the proposition that PMCT could be used as screening test. In an 11-week period, 39 deceased persons were referred for medicolegal investigation with pre-existing or subsequent nasopharyngeal swabs showing positivity on SARS-CoV-2 RT-PCR testing. All 39 had routine whole-body CT scans on admission and 12 underwent medicolegal autopsy. These cases were contrasted with 4 others which were negative on nasopharyngeal swabs despite PMCT findings suggestive of CoVID-19 pne...
Source: Forensic Science, Medicine, and Pathology - June 23, 2021 Category: Forensic Medicine Source Type: research

Bile pulmonary embolism-related sudden death following an abdominal firearm injury: An autopsy case report and review of literature
This article reports a fatal BPE in a 12-year-old child who died 14  days following an abdominal firearm injury. The right lobe of the liver had a yellowish-green stained lacerated track along with bile collection. Both lungs were congested with peripheral dark areas in all lobes. Microscopically, many interstitial pulmonary arterioles were occluded by bile emboli along with the presence of hemorrhagic infarcts. Other than the present case, only 21 cases of BPE were published in the literature until the present day. The history of hepatic trauma and/or hepatobiliary disease in association with pulmonary manifestations...
Source: Forensic Science, Medicine, and Pathology - June 23, 2021 Category: Forensic Medicine Source Type: research

Clandestine mummified remains
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - June 16, 2021 Category: Forensic Medicine Source Type: research

The mysterious hole in the skull of Pope Celestin V
AbstractCelestine V is considered one of the most enigmatic Popes. He has been the subject of much speculation, with legends claiming he was murdered by order of his successor Boniface VIII.  Assassination rumors first started in medieval times, but they were renewed in 1630 by the discovery of a nail that fitted perfectly into a square opening in his skull. During the latest Canonical Recognition, the morphology of the lesion was examined by visual inspection, showing it could not hav e been produced during life. The legend that the nail was driven through the Pope’s head may finally be discredited. (Source: Fo...
Source: Forensic Science, Medicine, and Pathology - June 11, 2021 Category: Forensic Medicine Source Type: research

Autopsy case of fatal hypoglycemia following ingestion of a therapeutic dose of tramadol
AbstractAn 86-year-old female was found unconscious the day after taking a prescribed tablet containing a combination of tramadol and acetaminophen. At admission to the hospital, marked hypoglycemia (blood glucose: 4  mg/dL) was confirmed, but serum insulin and C-peptide were within the normal range, which suggested that neither endogenous hyperinsulinemia nor exogenous insulin administration was responsible for the hypoglycemia. Despite resuscitation efforts, the woman subsequently died. At autopsy, there was renal disorder, but any pathological abnormalities that could have caused hypoglycemia were not observed. Blo...
Source: Forensic Science, Medicine, and Pathology - June 9, 2021 Category: Forensic Medicine Source Type: research

Computerized delineation of the teeth and comparison with a smiling photograph: identification of a body skeletonized by cadaverous ichthyofauna  action
This report also highlights the ferocity ofCetopsis candiru (candiru cobra),Cetopsis coecutiens (candiru-a çu) andCalophysus macropterus (piracatinga). (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - June 9, 2021 Category: Forensic Medicine Source Type: research

Death caused by a domestic pig attack
We report the case of a 49-year-old male found dead in his farm's pigsty, where a sow and her piglets were present. At the postmortem examination, numerous, severe blunt force injuries were observed on the body, with special regard to the upper extremities where massive injuries involving soft tissues, bones, and regional vessels, tendons, and nerves were present. The death resulted from severe bleeding from massive upper extremities injuries due to a domestic pig attack. Domestic pigs are usually placid but they can become aggressive if disturbed and attack humans producing severe injuries due to trampling, kicking and bi...
Source: Forensic Science, Medicine, and Pathology - June 9, 2021 Category: Forensic Medicine Source Type: research

Cinematic rendering of a burst sagittal suture caused by an occipito-frontal gunshot wound
AbstractThe computed tomography (CT) scan of a 19-year-old man who died from an occipito-frontal gunshot wound presented an impressive radiating fracture line where the entire sagittal suture burst due to the high intracranial pressure that arose from a near-contact shot from a 9  mm bullet fired from a Glock 17 pistol. Photorealistic depictions of the radiating fracture lines along the cranial bones were created using three-dimensional reconstruction methods, such as the novel cinematic rendering technique that simulates the propagation and interaction of light when it pas ses through volumetric data. Since the brain...
Source: Forensic Science, Medicine, and Pathology - June 9, 2021 Category: Forensic Medicine Source Type: research

Train-related suicidal decapitation
AbstractSuicide by decapitation as a primary method of injury is not common. When decapitation does occur in association with suicide, it may be a secondary consequence of the primary method of suicide, for example massive blunt force trauma, or hanging with a significant drop; however, primary suicidal decapitation has been described specifically in the context of railway incidents wherein victims lie across railroad tracks in-front of oncoming trains. Herein we report the case of a 49-year-old male who was decapitated after lying-down with his neck atop a railroad track in a railroad stockyard. He was subsequently run ov...
Source: Forensic Science, Medicine, and Pathology - June 9, 2021 Category: Forensic Medicine Source Type: research

The handling of SARS-CoV-2 associated deaths  - infectivity of the body
In this study, we present the results of infectivity testing of the body and testing of mortuary staff for SARS-CoV-2. We performed real-time quantitative polymerase chain reaction (RT-qPCR) for SARS-CoV-2 on 33 decedents with ante mortem confirmed SARS-CoV-2 infection. Swabs of the body surface from five different body regions and from the body bag or coffin were examined. A subset of the swabs was brought into cell culture. In addition, screening of 25 Institute of Legal Medicine (ILM) personnel for ongoing or past SARS-CoV-2 infection was performed at two different time points during the pandemic. Swabs from all lo...
Source: Forensic Science, Medicine, and Pathology - June 2, 2021 Category: Forensic Medicine Source Type: research

Does listing of individual contributions in “Mega-Authorship” papers always follow best practice guidelines?
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - June 1, 2021 Category: Forensic Medicine Source Type: research

Ectopic right thoracic kidney associated with Bochdalek hernia as the cause of diagnostic confusion
AbstractA 61-year-old man who was a psychiatric patient and an alcoholic was admitted to hospital after a fall in his bathroom. He showed signs of hemorrhagic shock, and CT scans showed the presence of the right kidney and part of the right retroperitoneum in the right hemithorax, surrounded by liquid. Surgery showed that the right hemidiaphragm was intact and that no intraabdominal viscera prolapsed into thoracic cavity. The bleeding in the right retroperitoneum was evacuated. The surgical report also stated that “the right kidney and ureter were explored and no injuries or active bleeding were found”. The pat...
Source: Forensic Science, Medicine, and Pathology - June 1, 2021 Category: Forensic Medicine Source Type: research

Autopsy findings in drivers and passengers from fatal motor vehicle collisions: limited differences in injury patterns and toxicological test results
AbstractWe performed a retrospective study of the injuries and characteristics of occupant fatalities in motor vehicle collisions in southeast Norway. The goal was to provide updated knowledge of injuries sustained in modern vehicles and detect possible differences in injury pattern between drivers and passengers. Forensic autopsy reports, police, and collision investigation reports from 2000 to 2014 were studied, data extracted and analyzed.A total of 284 drivers, 80 front-seat passengers, and 37 rear-seat passengers were included, of which 67.3% died in front collisions, 13.7% in near-side impacts, 13.5% in rollovers and...
Source: Forensic Science, Medicine, and Pathology - May 13, 2021 Category: Forensic Medicine Source Type: research

An alarming rise in the prevalence of deaths with methamphetamine involved in Tehran, Iran 2011-2018
Abstract Methamphetamine is one of the most commonly abused illicit drugs in Iran. Despite this fact, there has been relatively little research on methamphetamine-associated deaths in Iran. The present study aimed to investigate the cause of death in methamphetamine positive cases based on forensic toxicology findings In this data base descriptive study, individuals with methamphetamine-associated deaths that were referred to the Legal Medicine Organization, Tehran, Iran (2011-2018) were assessed. Deaths including those from natural causes, toxicity, accident and suicides with positive forensic toxicology analyses for ...
Source: Forensic Science, Medicine, and Pathology - May 13, 2021 Category: Forensic Medicine Source Type: research

Heart of glass: fatal hematemesis caused by bronchiole-cardiac fistula
AbstractA 58-year old woman presented for autopsy after having been found unresponsive in a public bathroom surrounded by a pool of blood. During attempts at resuscitation, blood was noted in her airway. She had a past medical history that included surgical repair of Tetralogy of Fallot as a child. At autopsy, a shard of glass was identified projecting from the surface of the left lung, having formed densely fibrotic adhesions at the pleural surface. The glass also penetrated through a bronchiole lumen and into a previously surgically repaired bulging right ventricular outflow tract, forming a bronchiole-cardiac fistula, a...
Source: Forensic Science, Medicine, and Pathology - May 13, 2021 Category: Forensic Medicine Source Type: research

Post-mortem persistence of SARS-CoV-2: a preliminary study
AbstractSince the beginning of March 2020, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has been the cause of millions of deaths worldwide. The need to better define the pathogenesis of coronavirus disease 19 (Covid-19) as well as to provide the correct statistical records concerning deaths related to this virus, inevitably involves the role of forensic pathology and routine autopsy practice. Currently, some data on macroscopic and microscopic features in autopsies performed in suspected Covid-19 cases are reported in the literature. The persistence of SARS-CoV-2 in cadavers has not yet been el...
Source: Forensic Science, Medicine, and Pathology - May 8, 2021 Category: Forensic Medicine Source Type: research

An autopsy case of sodium nitrite-induced methemoglobinemia with various post-mortem analyses
This report details the case of a 28-year-old man; the man had posted on a social network service detailing his attempt at suicide at 13:45. In the posted article, he stated that he had ingested 84  g of sodium nitrite. A post-mortem (PM) inspection was performed at 21:00, and peripheral blood (PB) was collected. An autopsy was performed approximately 44 h after death. The victim’s face was dark brown in color, but the color of his oral mucosa was bright red. Toxicological analyses reveale d 33% and 26% methemoglobinemia in the PB collected during PM inspection and autopsy, respectively. The concentration o...
Source: Forensic Science, Medicine, and Pathology - May 7, 2021 Category: Forensic Medicine Source Type: research

A rare case of sudden death due to aortogastric fistula after endovascular aortic repair of the descending aorta
We report the case of a 77-year-old woman who was admitted to the hospital due to severe mid-thoracic chest pain and was diagnosed with upper gastrointestinal bleeding. Her medical history included an aneurysm of the descending thoracic aorta, which was treated using the Thoracic Endovascular Repair (TEVAR) method several months prior. The patient died a few hours later amid hemorrhagic shock. The autopsy confirmed the upper gastrointestinal bleeding and revealed a fistula between the descending thoracic aorta and stomach, which were in anatomic contact because of a sliding hiatus hernia. (Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - May 5, 2021 Category: Forensic Medicine Source Type: research

Various fatal complications of urolithiasis
This article describes two cases of fatal complications of urolithiasis. The first case discusses the development of fatal urosepsis in a patient with a known mental health issue. The patient had self-introduced a thermometer into her bladder, which led to stone formation around the thermometer and consequently to fatal urosepsis. The second case deals with a motor vehicle accident in which a passenger with pre-existing hydronephrosis suffered a kidney injury leading to fatal bleeding into the surrounding adipose tissue. To provide a wider context, the paper also discusses the fatal complications and origin of urolithiasis...
Source: Forensic Science, Medicine, and Pathology - May 5, 2021 Category: Forensic Medicine Source Type: research

Regarding “The ongoing loss of historical material from institutions“
(Source: Forensic Science, Medicine, and Pathology)
Source: Forensic Science, Medicine, and Pathology - May 5, 2021 Category: Forensic Medicine Source Type: research

Postmortem diagnostics of assumed suicidal food anaphylaxis in prison: a unique case of anaphylactic death due to peach ingestion
AbstractSuicidal ingestion of food which the victim is aware they are allergic to is an exceptional occurrence in the forensic field. To the best of our knowledge, no cases of suicidal food anaphylaxis have been reported to date. Therefore we present the first case described in the literature. A 30-year-old prisoner was found dead inside his cell with the remains of a peach remains next to his body, and a handwritten farewell note in his pocket.  The autopsy revealed only non-specific findings, while laboratory investigations (serological, toxicological, histological, and immunohistochemical) played a pivotal role in ...
Source: Forensic Science, Medicine, and Pathology - May 3, 2021 Category: Forensic Medicine Source Type: research

The banding phenomenon: injury or hypostasis?
We describe a case of a 30-year-old man who was found dead in a hotel courtyard, facedown. The window of his hotel room on the 5th floor was wide open. Police investigation revealed that he was a gambler with many debts, leading them to suspect foul play. The body was transported for a forensic autopsy in a supine position. External examination showed multiple lacerations and contusions of the face and limbs, without signs of external neck injuries. Layer-by-layer neck dissection was unremarkable. Upon opening the pharynx and esophagus, dark purple discoloration of the pharyngeal mucosa could be seen, with a clearly define...
Source: Forensic Science, Medicine, and Pathology - May 3, 2021 Category: Forensic Medicine Source Type: research

Autopsy assessment of pediatric head injury: a proposal for aerosol mitigation during the COVID-19 pandemic
AbstractDuring the Corona Virus Disease-19 (COVID-19) pandemic, there is still a requirement for post-mortems to continue, including those examinations performed in the context of medico-legal investigations. Currently, very little is known about how long this coronavirus can survive in deceased human bodies or whether un-embalmed human cadavers can be contagious to people who handle them. Therefore, it would appear to be prudent to consider implementation of additional safety measures for all necessary post-mortem procedures. During the post-mortem examination of babies and young children, it is important to open the calv...
Source: Forensic Science, Medicine, and Pathology - May 3, 2021 Category: Forensic Medicine Source Type: research