Fasting Plasma Glucose Levels at the Time of Admission Predict 90-Day Mortality in Patients with Viral Pneumonia. A Prospective Study
Conclusions The higher the FPG level at admission in a patient with viral pneumonia, the higher the risk of all-cause mortality within 90 d. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 17, 2023 Category: Endocrinology Authors: Xu, Jie Zhao, Jianyu Wu, Liyuan Lu, Xinxin Tags: Article Source Type: research

Effects of Dietary Sodium and Protein Intake on Glomerular Filtration Rate in Subjects with Type 2 Diabetes Treated with Sodium-Glucose Cotransporter 2 Inhibitors
Conclusions The present study suggests that a higher dietary sodium and protein intake may amplify the extent of the early dip in GFR, as detected with measured CrCl, in diabetic patients undergoing SGLT2i treatment. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 17, 2023 Category: Endocrinology Authors: Gaudio, Costanza Seghieri, Marta Merciai, Chiara Colombi, Claudia Spatoliatore, Giuseppe Baggiore, Cristiana Maria Rosati, Alberto Tags: Article Source Type: research

Pituitary Surgery in Germany – Findings from the European Pituitary Adenoma Surgery Survey
Conclusions The data showed differences as well as similarities between centers and could help to discuss the standardization of methods and the formation of networks and certification to improve patient care. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 12, 2023 Category: Endocrinology Authors: Ottenhausen, Malte Conrad, Jens Kalasauskas, Darius Netuka, David Ringel, Florian Tags: Article Source Type: research

Improving Detection Rates for Primary Aldosteronism
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-2048-6213Primary aldosteronism (PA), once considered a rare disease, is being increasingly recognized as an important cause of hypertension. It is associated with higher rates of cardiovascular complications compared to blood pressure-matched essential hypertension. Targeted treatments are available which can mitigate the excess cardiovascular risks and, in some cases, cure hypertension. Making a timely diagnosis of PA is, therefore, highly beneficial for patients. Furthermore, numerous studies from different parts of th...
Source: Experimental and Clinical Endocrinology and Diabetes - May 9, 2023 Category: Endocrinology Authors: Libianto, Renata Stowasser, Michael Russell, Grant Fuller, Peter J Yang, Jun Tags: Review Source Type: research

The Prevalence of Primary Aldosteronism in Screening Populations: Is Hypokalaemia Important?
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-2075-0735 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - May 9, 2023 Category: Endocrinology Authors: Williams, David M Shaikh, Ayesha Williams, Ellen Maroof, Aiman Michael, Therese Boregowda, Kusuma Tags: Letter to the Editor Source Type: research

An Abbreviated History of Aldosterone Metabolism, Current and Future Challenges
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-2054-1062The initial isolation of adrenal steroids from large quantities of animal adrenals resulted in an amorphous fraction resistant to crystallization and identification and had potent effects on electrolyte transport. Aldosterone was eventually isolated and identified in the fraction and was soon shown to cause hypertension when in excess. The autonomous and excessive production of aldosterone, primary aldosteronism, is the most common cause of secondary hypertension. Aldosterone is metabolized in the liver and kidn...
Source: Experimental and Clinical Endocrinology and Diabetes - May 8, 2023 Category: Endocrinology Authors: Gomez-Sanchez, Celso E Gomez-Sanchez, Elise P Tags: Review Source Type: research

Prediction of Hypoglycemia in Diabetic Patients During Colonoscopy Preparation
Conclusion Diabetic patients are prone to develop mild to moderate hypoglycemia during colonoscopy preparation. This study proposes a predictive model that could provide a reference for identifying patients with a high risk of hypoglycemia during colonoscopy preparation. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 26, 2023 Category: Endocrinology Authors: Lu, Xiaohua Xie, Lingqiao Zhao, Wane Zhang, Chuangbiao Luo, Xixi Zhou, Yan Tags: Article Source Type: research

Increased Galactosidase Beta 1 Expression as a Senescent Key Factor in β-Cells Function Modulation at the Early Steps of Type 2 Diabetes
Conclusion The study findings indicate that senescence, as revealed by an increase in GLB1 expression, is a key factor in the initial stage of diabetes. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 18, 2023 Category: Endocrinology Authors: Maduro, Ana T. Pinto, Anabela Ferreira-Gomesb, Joana Costa, Raquel Soares, Raquel Lu ís, Carla Tags: Article Source Type: research

Effects of Growth Hormone on Muscle and Bone in Female Mice: Role of Follistatin
Exp Clin Endocrinol Diabetes 2023; 131: 228-235 DOI: 10.1055/a-2003-5704The interactions between muscle and bone are noted in the clinical relationships between sarcopenia and osteoporosis. Myokines secreted from the skeletal muscles play roles in muscle-bone interactions related to various physiological and pathophysiological states. Although numerous evidence suggests that growth hormone (GH) influences both muscle and bone, the effects of GH on the muscle-bone interactions have remained unknown. We, therefore, investigated the influences of GH administration fo...
Source: Experimental and Clinical Endocrinology and Diabetes - April 13, 2023 Category: Endocrinology Authors: Ohira, Takashi Kawao, Naoyuki Takafuji, Yoshimasa Mizukami, Yuya Kaji, Hiroshi Tags: Article Source Type: research

Screening Results for Diabetic Retinopathy in Germany in a Real-world Cohort in a Metropolitan Diabetes Care Center
Discussion Despite a high screening performance in a real-world setting, complete screening in compliance with German guidelines, including written reporting, was found in less than half of the cohort. The prevalence and incidence of DR are high. Even when referred according to the regulations, one-quarter of patients made a co-payment. Efficient solutions to current barriers can emerge with mutual time-saving information prior to examination and feedback about the implementation of findings into treatment. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 St...
Source: Experimental and Clinical Endocrinology and Diabetes - April 13, 2023 Category: Endocrinology Authors: Mertes, Bernardo Kuniss, Nadine Piorkowski, Michael Mertes, Linus Paul Hammes, Hans-Peter Tags: Article Source Type: research

Many Faces of Adrenal Lesions in a Large Patient Cohort: What Has Changed Over the Last Two Decades?
Conclusions Adrenal lesions are common in the adult population, and while it is important to avoid overtreatment, hormone secretion, and malignancy should not be overlooked. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 3, 2023 Category: Endocrinology Authors: Saydam, Basak Ozgen Baris, Mustafa Adiyaman, Suleyman Cem Demir, Tevfik Kocdor, Mehmet Ali Demir, Omer Secil, Mustafa Yener, Serkan Tags: Article Source Type: research

Mind the gap: Measured and Calculated Osmolarity are Not Interchangeable in Diabetic Hyperglycemic Emergencies
Conclusions The osmolar gap varies widely in diabetic ketoacidosis and the hyperosmolar hyperglycemic state and may be highly elevated, especially at admission. Clinicians should be aware that measured and calculated osmolarity values are not interchangeable in this population. These findings should be confirmed in a prospective study. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - April 3, 2023 Category: Endocrinology Authors: Blank, Sebastiaan Paul Blank, Ruth Miriam Tags: Article Source Type: research

Association of Aldosterone with Mortality in the General Population
Conclusions Aldosterone was associated with all-cause mortality in the population-based KORA F4 study, but the previously described associations of excess aldosterone with cardiovascular complications and biomarkers of subclinical inflammation could not be shown. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 20, 2023 Category: Endocrinology Authors: Then, Cornelia Herder, Christian Heier, Margit Meisinger, Christa Koenig, Wolfgang Rathmann, Wolfgang Sujana, Chaterina Roden, Michael Bidlingmaier, Martin Seissler, Jochen Thorand, Barbara Peters, Annette Reincke, Martin Tags: Article Source Type: research

E2F2 Promotes Wound Healing of Diabetic Foot Ulcer by Regulating CDCA7L Transcription
Conclusions E2F2 facilitated cell proliferation and migration and fostered wound healing in DFU cells through binding to the CDCA7L promoter. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Experimental and Clinical Endocrinology and Diabetes)
Source: Experimental and Clinical Endocrinology and Diabetes - March 9, 2023 Category: Endocrinology Authors: Xiao, Meimei Wang, Jiusong Chen, Yanming Tags: Article Source Type: research

Glucometabolic Perturbations in Type 2 Diabetes Mellitus and Coronavirus Disease 2019: Causes, Consequences, and How to Counter Them Using Novel Antidiabetic Drugs – The CAPISCO International Expert Panel
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-2019-1111The growing amount of evidence suggests the existence of a bidirectional relation between coronavirus disease 2019 (COVID-19) and type 2 diabetes mellitus (T2DM), as these two conditions exacerbate each other, causing a significant healthcare and socioeconomic burden. The alterations in innate and adaptive cellular immunity, adipose tissue, alveolar and endothelial dysfunction, hypercoagulation, the propensity to an increased viral load, and chronic diabetic complications are all associated with glucometabolic p...
Source: Experimental and Clinical Endocrinology and Diabetes - March 8, 2023 Category: Endocrinology Authors: Popovic, Djordje S. Papanas, Nikolaos Koufakis, Theocharis Kotsa, Kalliopi Mahmeed, Wael Al Al-Rasadi, Khalid Al-Alawi, Kamila Banach, Maciej Banerjee, Yajnavalka Ceriello, Antonio Cesur, Mustafa Cosentino, Francesco Firenze, Alberto Galia, Massimo Goh, S Tags: Review Source Type: research